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Rat Strains

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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1Condition 2Condition 3Condition 4Condition 5
5systolic blood pressureWKYmale97.8mmHgsham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100315sham surgical control condition (for 224 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
16systolic blood pressureWKYmale79.5mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100316left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
32systolic blood pressureWKYmale75.1mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100317left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ramipril (1 mg/kg/d) (for 182 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
5diastolic blood pressureWKYmale63.3mmHgsham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100318sham surgical control condition (for 224 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
16diastolic blood pressureWKYmale53mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100319left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
32diastolic blood pressureWKYmale47.6mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100320left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ramipril (1 mg/kg/d) (for 182 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
5left ventricular end-systolic blood pressureWKYmale93mmHgsham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100321sham surgical control condition (for 224 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
16left ventricular end-systolic blood pressureWKYmale73.5mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100322left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
32left ventricular end-systolic blood pressureWKYmale67.5mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100323left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ramipril (1 mg/kg/d) (for 182 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
5left ventricular end-diastolic blood pressureWKYmale5.5mmHgsham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100324sham surgical control condition (for 224 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
16left ventricular end-diastolic blood pressureWKYmale9.36mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100325left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
32left ventricular end-diastolic blood pressureWKYmale5.96mmHgleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100326left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ramipril (1 mg/kg/d) (for 182 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
5maximum rate of positive change in left ventricular blood pressureWKYmale4225mmHg/ssham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100327sham surgical control condition (for 224 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
16maximum rate of positive change in left ventricular blood pressureWKYmale2912mmHg/sleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100328left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ketamine (80 mg/kg) xylazine (10 mg/kg)
32maximum rate of positive change in left ventricular blood pressureWKYmale2882mmHg/sleft anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) 100329left anterior descending coronary artery occlusion (for 224 days)furosemide (10 mg/kg/d) (for 161 days)ramipril (1 mg/kg/d) (for 182 days)ketamine (80 mg/kg) xylazine (10 mg/kg)