Phenominer Database Results (61 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Clinical Measurement Notes Record ID Study ID
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 0.04 nl/(s x mmHg) 0.0 0.01 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg kf 100590 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 1.24 ml/min 0.07 0.16 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 100598 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 67.0 nl/min 13.0 29.07 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg sngfr 100608 2479
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 0.06 nl/(s x mmHg) 0.02 0.04 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg kf 100616 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 6 17.0 nl/min 2.0 4.9 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days sngfr 100518 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 50.0 nl/min 3.0 9.0 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg sngfr 100520 2479
WKY single nephron glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 8 61.0 nl/min 3.0 8.49 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 100521 2479
WKY afferent arteriolar plasma flow rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male  days 8 191.0 nl/min 16.0 45.25 inulin analysis by liquid phase colorimetry 0.0 afferent arteriolar plasma flow rate 100529 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male  days 9 169.0 nl/min 14.0 42.0 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg afferent arteriolar plasma flow rate 100530 2479
WKY glomerular capillary hydraulic pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male  days 6 50.0 mmHg 3.0 7.35 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days pgc 100533 2479
WKY glomerular capillary hydraulic pressure 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male  days 8 47.0 mmHg 2.0 5.66 inulin analysis by liquid phase colorimetry 0.0 pgc 100534 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 8 0.54 ml/min/100g 0.02 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99948 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 8 0.23 null 0.14 0.4 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99958 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 11 0.52 ml/min/100g 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99980 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 17 0.69 ml/min/100g 0.03 0.13 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99982 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 11 0.23 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99985 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 16 0.22 null 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99988 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 16 0.21 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99989 2378
WKY glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 8 1.34 ml/min 0.06 0.17 inulin analysis by liquid phase colorimetry 0.0 100457 2479
WKY glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 497 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 1.43 ml/min 0.09 0.27 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 490 days 100462 2479
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 17 0.21 null 0.01 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99987 2378
WKY glomerular capillary ultrafiltration coefficient 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 0.07 nl/(s x mmHg) 0.01 0.04 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 kf 100587 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 1.22 ml/min 0.03 0.07 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 100596 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 57.0 nl/min 8.0 17.89 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg sngfr 100611 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 8 1.14 ml/min 0.13 0.37 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 490 days 100461 2479
WKY glomerular capillary hydraulic pressure puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male  days 9 68.0 mmHg 2.0 6.0 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg pgc 100535 2479
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 8 0.26 null 0.01 0.04 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99956 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 8 0.23 null 0.12 0.34 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99957 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) and bosentan (100 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 16 0.67 ml/min/100g 0.02 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99984 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 17 0.29 null 0.01 0.05 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99986 2378
WKY glomerular capillary ultrafiltration coefficient controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 8 0.11 nl/(s x mmHg) 0.03 0.07 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg kf 100591 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 7 0.31 ml/min 0.05 0.13 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days 100455 2479
WKY glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 1.51 ml/min 0.12 0.36 inulin analysis by liquid phase colorimetry 0.0 100460 2479
WKY glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 8 1.25 ml/min 0.09 0.25 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 100459 2479
WKY glomerular capillary hydraulic pressure 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male  days 9 49.0 mmHg 1.0 3.0 inulin analysis by liquid phase colorimetry 0.0 pgc 100532 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male  days 6 186.0 nl/min 17.0 41.64 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days afferent arteriolar plasma flow rate 100528 2479
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 6 0.21 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99959 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 154 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 16 0.66 ml/min/100g 0.02 0.09 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99983 2378
WKY glomerular capillary ultrafiltration coefficient 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 8 0.09 nl/(s x mmHg) 0.01 0.03 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 kf 100589 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 1.49 ml/min 0.09 0.2 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 100597 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 82.0 nl/min 10.0 22.36 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg sngfr 100609 2479
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) then saralasin (0.3 mg/kg/hr) (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 0.16 nl/(s x mmHg) 0.05 0.1 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg kf 100617 2479
WKY glomerular filtration rate controlled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 0.38 ml/min 0.08 0.18 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 15 days 100456 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 1.28 ml/min 0.06 0.18 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 100458 2479
WKY afferent arteriolar plasma flow rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male  days 9 165.0 nl/min 17.0 51.0 inulin analysis by liquid phase colorimetry 0.0 afferent arteriolar plasma flow rate 100527 2479
WKY glomerular capillary hydraulic pressure controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. blood molecular composition trait male  days 8 46.0 mmHg 2.0 5.66 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg pgc 100536 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 8 0.79 ml/min/100g 0.03 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99946 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 8 0.52 ml/min/100g 0.03 0.07 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99947 2378
WKY glomerular capillary ultrafiltration coefficient puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 6 0.02 nl/(s x mmHg) 0.0 0.01 inulin analysis by liquid phase colorimetry glomerular capillary 0.0 PA IV 50mg/kg 15 days kf 100588 2479
WKY glomerular filtration rate puromycin aminonucleoside (50 mg/kg) then 0.9% sodium chloride solution (for 0.5 hours) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 1.19 ml/min 0.08 0.18 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg 100599 2479
WKY single nephron glomerular filtration rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 5 65.0 nl/min 9.0 20.12 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg sngfr 100610 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male  days 5 270.0 nl/min 44.0 98.39 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg qa 100612 2479
WKY afferent arteriolar plasma flow rate puromycin aminonucleoside (50 mg/kg) (for 0.5 hours) then saralasin (0.3 mg/kg/hr) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male  days 5 314.0 nl/min 34.0 76.03 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg qa 100613 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 17 0.5 ml/min/100g 0.03 0.12 inulin analysis by liquid phase colorimetry 0.0 unx 168 days 99981 2378
WKY glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 1.17 ml/min 0.05 0.15 inulin analysis by liquid phase colorimetry 0.0 100454 2479
WKY single nephron glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 9 44.4 nl/min 4.0 12.0 inulin analysis by liquid phase colorimetry 0.0 sngfr 100517 2479
WKY single nephron glomerular filtration rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. glomerular filtration trait male  days 8 52.0 nl/min 3.0 8.49 inulin analysis by liquid phase colorimetry 0.0 sngfr 100519 2479
WKY afferent arteriolar plasma flow rate controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. kidney plasma flow trait male  days 8 244.0 nl/min 21.0 59.4 inulin analysis by liquid phase colorimetry 0.0 PA IV 50mg/kg afferent arteriolar plasma flow rate 100531 2479
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 7 0.49 ml/min/100g 0.03 0.08 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99945 2378
WKY glomerular filtration rate to body weight ratio unilateral nephrectomy (for 28 days) then streptozotocin (35 mg/kg) then enalapril (10 mg/kg/d) (for 14 days) and bosentan (100 mg/kg/d) (for 14 days) Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 6 0.5 ml/min/100g 0.02 0.06 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99949 2378
WKY renal filtration fraction unilateral nephrectomy (for 28 days) then vehicle control condition Ding SS, et al., J Cardiovasc Pharmacol. 2003 Jul;42(1):48-54. glomerular filtration trait male  days 7 0.23 null 0.01 0.03 inulin analysis by liquid phase colorimetry 0.0 unx 28 days 99955 2378