Phenominer Database Results (28 results)

 

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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Sample Notes Experiment Notes Record ID Study ID
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 1.61 ng/ml/h 0.88 2.33 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52919 482
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data blood creatinine amount female 80.0 days-99.0 days 15 0.35 mg/dl 0.02 0.08 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52236 482
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 1.01 ng/ml/h 0.15 0.43 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52480 482
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data blood creatinine amount male 87.0 days-120.0 days 3 0.29 mg/dl 0.0 0.01 radioimmunoassay Moms and pups used in studies were fed Teklad 51321 481
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data blood creatinine amount male 87.0 days-120.0 days 3 0.28 mg/dl 0.03 0.05 radioimmunoassay Moms and pups used in studies were fed Teklad 51655 481
BN/NHsdMcwi serum triiodothyronine level controlled ethanol content drinking water used as vehicle (0.1 %) (for 70 days) Wagner VA, etal., Toxicol Sci. 2023 Jun 28;194(1):84-100. doi: 10.1093/toxsci/kfad046. blood triiodothyronine amount male 91.0 days 8 70.24 µg/dL 4.85 13.71 radioimmunoassay RIA; RRID:AB_2940789 Serum total T3 Changed sex from M to male to standardize across records, 7-30-2024 139039 3292
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 3 2.06 ng/ml/h 0.69 1.19 radioimmunoassay Moms and pups used in studies were fed Teklad 51844 481
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data blood creatinine amount male 80.0 days-99.0 days 8 0.24 mg/dl 0.03 0.07 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52283 482
BN/NHsdMcwi urine albumin excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine albumin amount male 80.0 days-99.0 days 10 4.05 mg/d 1.24 3.93 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52625 482
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data blood creatinine amount female 87.0 days-120.0 days 2 0.26 mg/dl 0.06 0.08 radioimmunoassay Moms and pups used in studies were fed Dyets 51179 481
BN/NHsdMcwi serum thyroxine level controlled ethanol content drinking water used as vehicle (0.1 %) (for 70 days) Wagner VA, etal., Toxicol Sci. 2023 Jun 28;194(1):84-100. doi: 10.1093/toxsci/kfad046. blood thyroxine amount male 91.0 days 8 4.19 ng/dL 0.21 0.6 radioimmunoassay RIA; RRID:AB_2940788 Serum total T4 Changed sex from M to male to standardize across records, 7-30-2024 139040 3292
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data blood creatinine amount female 87.0 days-120.0 days 2 0.27 mg/dl 0.04 0.06 radioimmunoassay Moms and pups used in studies were fed Dyets 52043 481
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 0.26 ng/ml/h 0.03 0.08 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52918 482
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data blood creatinine amount male 80.0 days-99.0 days 8 0.41 mg/dl 0.02 0.06 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52235 482
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 3 7.64 ng/ml/h 1.68 2.91 radioimmunoassay Moms and pups used in studies were fed Teklad 51015 481
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 1 8.99 ng/ml/h radioimmunoassay Moms and pups used in studies were fed Teklad 51014 481
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data blood creatinine amount female 87.0 days-120.0 days 6 0.28 mg/dl 0.0 0.01 radioimmunoassay Moms and pups used in studies were fed Teklad 51656 481
BN/NHsdMcwi serum triiodothyronine level controlled ethanol content drinking water used as vehicle (0.1 %) (for 70 days) Wagner VA, etal., Toxicol Sci. 2023 Jun 28;194(1):84-100. doi: 10.1093/toxsci/kfad046. blood triiodothyronine amount female 91.0 days 7 77.7 µg/dL 3.4 9.0 radioimmunoassay RIA; RRID:AB_2940789 Serum total T3 Changed sex from F to female to standardize across records, 7-30-2024 138923 3292
BN/NHsdMcwi plasma insulin level controlled sodium chloride content drinking water (1 %) (for 7 days) then controlled sodium chloride content drinking water (2 %) (for 7 days) then controlled sodium chloride content drinking water (1 %) (for 9 days) then water (for 12 days) Gilibert S, et al., J Hypertens. 2009 Jun;27(6):1186-93. blood insulin amount male 175.0 days 10 20.37 mU/l 0.91 2.88 radioimmunoassay 0.0 102092 2645
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 1.48 ng/ml/h 0.33 0.74 radioimmunoassay Moms and pups used in studies were fed Teklad 51845 481
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data blood creatinine amount female 87.0 days-120.0 days 3 0.3 mg/dl 0.02 0.04 radioimmunoassay Moms and pups used in studies were fed Teklad 51322 481
BN/NHsdMcwi serum thyroxine level controlled ethanol content drinking water used as vehicle (0.1 %) (for 70 days) Wagner VA, etal., Toxicol Sci. 2023 Jun 28;194(1):84-100. doi: 10.1093/toxsci/kfad046. blood thyroxine amount female 91.0 days 7 3.47 ng/dL 0.19 0.51 radioimmunoassay RIA; RRID:AB_2940788 Serum total T4 Changed sex from F to female to standardize across records, 7-30-2024 138924 3292
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data blood creatinine amount female 80.0 days-99.0 days 7 0.33 mg/dl 0.03 0.08 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52284 482
BN/NHsdMcwi urine albumin excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine albumin amount male 80.0 days-99.0 days 8 5.41 mg/d 1.01 2.85 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52426 482
BN/NHsdMcwi urine albumin excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine albumin amount female 80.0 days-99.0 days 11 7.16 mg/d 2.64 8.76 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52427 482
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 15 4.4 ng/ml/h 1.26 4.87 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52481 482
BN/NHsdMcwi urine albumin excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine albumin amount female 80.0 days-99.0 days 21 2.16 mg/d 0.38 1.73 radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52626 482
BN/NHsdMcwi plasma insulin level to plasma glucose level ratio controlled sodium chloride content drinking water (1 %) (for 7 days) then controlled sodium chloride content drinking water (2 %) (for 7 days) then controlled sodium chloride content drinking water (1 %) (for 9 days) then water (for 12 days) Gilibert S, et al., J Hypertens. 2009 Jun;27(6):1186-93. blood insulin amount male 175.0 days 10 2.76 mU/mmol 0.13 0.41 radioimmunoassay 0.0 mU/mmol plasma insulin level to plasma glucose level ratio (CMO:0003555) 102096 2645