| SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71.0 days-85.0 days |
6 |
|
3.65 |
g |
0.12 |
0.29 |
post excision weight measurement |
0.0 |
|
|
|
|
85194 |
1602 |
| SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
85.0 days-99.0 days |
6 |
|
3.51 |
g |
0.13 |
0.31 |
post excision weight measurement |
0.0 |
|
|
|
|
85205 |
1602 |
| SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71.0 days-85.0 days |
6 |
|
0.22 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85242 |
1602 |
| SD |
heart wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71.0 days-85.0 days |
6 |
|
0.42 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
|
|
|
85238 |
1602 |
| SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71.0 days-85.0 days |
6 |
|
0.24 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
|
|
|
85248 |
1602 |
| SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
85.0 days-99.0 days |
6 |
|
0.21 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
|
|
|
85247 |
1602 |
| SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
85.0 days-99.0 days |
6 |
|
0.24 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
|
|
|
85251 |
1602 |
| SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
85.0 days-99.0 days |
6 |
|
0.23 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
|
|
|
85253 |
1602 |
| SD |
brain wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71.0 days-85.0 days |
6 |
|
0.74 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
|
|
|
85256 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71.0 days-85.0 days |
6 |
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85268 |
1602 |
| SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71.0 days-85.0 days |
6 |
|
1.17 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
|
|
|
85263 |
1602 |
| SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
85.0 days-99.0 days |
6 |
|
1.09 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
|
|
|
85265 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
85.0 days-99.0 days |
6 |
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85271 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71.0 days-85.0 days |
6 |
|
0.04 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
|
|
|
85274 |
1602 |
| SD |
testis wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71.0 days-85.0 days |
6 |
|
1.19 |
g |
0.08 |
0.19 |
post excision weight measurement |
0.0 |
|
|
|
|
85279 |
1602 |
| SD |
testis wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71.0 days-85.0 days |
6 |
|
1.17 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
|
|
|
85280 |
1602 |
| SD |
testis wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
85.0 days-99.0 days |
6 |
|
1.01 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
|
|
|
85283 |
1602 |
| SD |
uterus wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71.0 days-85.0 days |
6 |
|
0.35 |
g |
0.06 |
0.15 |
post excision weight measurement |
0.0 |
|
|
|
|
85284 |
1602 |
| SD |
uterus wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
85.0 days-99.0 days |
6 |
|
0.35 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
|
|
|
85288 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71.0 days-85.0 days |
6 |
|
0.73 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
|
|
|
85227 |
1602 |
| SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
85.0 days-99.0 days |
6 |
|
0.79 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
|
|
|
85228 |
1602 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
720 |
min |
|
98787 |
2160 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.2 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
98790 |
2160 |
| SD |
left kidney wet weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 5 |
|
1.16 |
g |
0.11 |
0.25 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
remnant kidney |
101545 |
2602 |
| SD |
left kidney wet weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 5 |
|
1.49 |
g |
0.1 |
0.23 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
remnant kidney |
101546 |
2602 |
| SD |
heart wet weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
days
| 6 |
|
1.03 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
sham unx |
28 |
days |
|
101587 |
2602 |
| SD |
heart wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
days
| 7 |
|
0.88 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101589 |
2602 |
| SD |
heart wet weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
days
| 8 |
|
1.21 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101620 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 8 |
|
73.0 |
mg |
2.83 |
8.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101628 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 7 |
|
57.0 |
mg |
1.51 |
4.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101601 |
2602 |
| SD |
heart weight to body weight ratio |
sham surgical control condition (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
3.3 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
360 |
min |
|
98778 |
2160 |
| SD |
heart weight |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175.0 days
| 10 |
|
1.26 |
g |
0.03 |
0.09 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
99197 |
2278 |
| SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98.0 days
| 8 |
|
4.4 |
g/kg |
0.2 |
0.57 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
99200 |
2278 |
| SD |
heart right ventricle weight to body weight ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
98.0 days
| 8 |
|
0.5 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
99207 |
2278 |
| SD |
lung weight |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
98.0 days
| 8 |
|
1.84 |
g |
0.08 |
0.23 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
99212 |
2278 |
| SD |
both kidneys wet weight as percentage of body weight |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
kidney mass |
male |
60.0 days
| 3 |
|
0.72 |
% |
0.03 |
0.06 |
post excision weight measurement |
0.0 |
|
|
|
|
100192 |
2439 |
| SD |
left kidney wet weight |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
days
| 8 |
|
1.83 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
|
|
|
99919 |
2358 |
| SD |
liver wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71.0 days-85.0 days |
6 |
|
4.31 |
g |
0.14 |
0.35 |
post excision weight measurement |
0.0 |
|
|
|
|
85192 |
1602 |
| SD |
liver wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71.0 days-85.0 days |
6 |
|
4.31 |
g |
0.1 |
0.24 |
post excision weight measurement |
0.0 |
|
|
|
|
85193 |
1602 |
| SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
85.0 days-99.0 days |
6 |
|
0.76 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
|
|
|
|
85210 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71.0 days-85.0 days |
6 |
|
0.88 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
|
|
|
85209 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
85.0 days-99.0 days |
6 |
|
0.84 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
|
|
|
85211 |
1602 |
| SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
85.0 days-99.0 days |
6 |
|
0.36 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
|
|
|
85235 |
1602 |
| SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
85.0 days-99.0 days |
6 |
|
0.44 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85240 |
1602 |
| SD |
brain wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71.0 days-85.0 days |
6 |
|
0.72 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
|
|
|
85255 |
1602 |
| SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71.0 days-85.0 days |
6 |
|
0.75 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
|
|
|
|
85257 |
1602 |
| SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71.0 days-85.0 days |
6 |
|
0.04 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
|
|
|
85272 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71.0 days-85.0 days |
6 |
|
0.04 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85275 |
1602 |
| SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71.0 days-85.0 days |
6 |
|
3.64 |
g |
0.12 |
0.3 |
post excision weight measurement |
0.0 |
|
|
|
|
85200 |
1602 |
| SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
85.0 days-99.0 days |
6 |
|
3.56 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
|
|
|
|
85196 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71.0 days-85.0 days |
6 |
|
0.85 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
|
|
|
85213 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71.0 days-85.0 days |
6 |
|
0.88 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
|
|
|
85214 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71.0 days-85.0 days |
6 |
|
0.68 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
|
|
|
|
85220 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71.0 days-85.0 days |
6 |
|
0.77 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
|
|
|
85221 |
1602 |
| SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71.0 days-85.0 days |
6 |
|
0.39 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85230 |
1602 |
| SD |
uterus wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71.0 days-85.0 days |
6 |
|
0.45 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
|
|
|
|
85286 |
1602 |
| SD |
uterus wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
85.0 days-99.0 days |
6 |
|
0.27 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
|
|
|
85289 |
1602 |
| SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
85.0 days-99.0 days |
6 |
|
3.18 |
g |
0.13 |
0.31 |
post excision weight measurement |
0.0 |
|
|
|
|
85195 |
1602 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 5 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.7 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
5 |
days |
|
98791 |
2160 |
| SD |
left kidney wet weight |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 11 |
|
1.37 |
g |
0.07 |
0.23 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
remnant kidney |
101544 |
2602 |
| SD |
left kidney wet weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 6 |
|
1.19 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
sham unx |
28 |
days |
remnant kidney |
101579 |
2602 |
| SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 7 |
|
1.47 |
g |
0.07 |
0.18 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
remnant kidney |
101581 |
2602 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
98875 |
2160 |
| SD |
heart weight to body weight ratio |
sham surgical control condition (between 120 and 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
3.4 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
5 |
days |
|
98784 |
2160 |
| SD |
left kidney wet weight |
control condition |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
days
| 8 |
|
1.66 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
|
|
|
99895 |
2358 |
| SD |
left kidney wet weight |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney mass |
male |
420.0 days-450.0 days |
9 |
|
1.8 |
g |
0.12 |
0.36 |
post excision weight measurement |
0.0 |
|
|
|
|
101217 |
2582 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
175.0 days
| 10 |
|
1.9 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
99205 |
2278 |
| SD |
heart right ventricle weight to body weight ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
98.0 days
| 8 |
|
0.9 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
99208 |
2278 |
| SD |
heart right ventricle weight to body weight ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
175.0 days
| 10 |
|
0.5 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
99209 |
2278 |
| SD |
both kidneys wet weight as percentage of body weight |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
kidney mass |
male |
120.0 days
| 3 |
|
0.55 |
% |
0.03 |
0.06 |
post excision weight measurement |
0.0 |
|
|
|
|
100194 |
2439 |
| SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
days
| 8 |
|
2.18 |
g |
0.05 |
0.14 |
post excision weight measurement |
0.0 |
stz |
224 |
days |
|
99917 |
2358 |
| SD |
spleen wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
85.0 days-99.0 days |
6 |
|
0.17 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
|
|
|
85246 |
1602 |
| SD |
spleen wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71.0 days-85.0 days |
6 |
|
0.2 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
|
|
|
85244 |
1602 |
| SD |
spleen wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71.0 days-85.0 days |
6 |
|
0.26 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
|
|
|
85250 |
1602 |
| SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71.0 days-85.0 days |
6 |
|
0.24 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85252 |
1602 |
| SD |
brain wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
85.0 days-99.0 days |
6 |
|
0.68 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85259 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71.0 days-85.0 days |
6 |
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85267 |
1602 |
| SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
85.0 days-99.0 days |
6 |
|
1.09 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85264 |
1602 |
| SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
85.0 days-99.0 days |
6 |
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85270 |
1602 |
| SD |
testis wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71.0 days-85.0 days |
6 |
|
1.17 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
|
|
|
85278 |
1602 |
| SD |
testis wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
85.0 days-99.0 days |
6 |
|
1.0 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
|
|
|
85282 |
1602 |
| SD |
liver wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71.0 days-85.0 days |
6 |
|
3.7 |
g |
0.11 |
0.28 |
post excision weight measurement |
0.0 |
|
|
|
|
85203 |
1602 |
| SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71.0 days-85.0 days |
6 |
|
0.73 |
g |
0.09 |
0.23 |
post excision weight measurement |
0.0 |
|
|
|
|
85218 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
71.0 days-85.0 days |
6 |
|
0.72 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
|
|
|
85219 |
1602 |
| SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
85.0 days-99.0 days |
6 |
|
0.66 |
g |
0.06 |
0.14 |
post excision weight measurement |
0.0 |
|
|
|
|
85222 |
1602 |
| SD |
heart wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71.0 days-85.0 days |
6 |
|
0.37 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
|
|
|
85231 |
1602 |
| SD |
testis wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
testis mass |
male |
71.0 days-85.0 days |
6 |
|
1.03 |
g |
0.15 |
0.37 |
post excision weight measurement |
0.0 |
|
|
|
|
85281 |
1602 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.2 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
360 |
min |
|
98785 |
2160 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
720 |
min |
|
98788 |
2160 |
| SD |
left kidney wet weight |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 6 |
|
1.11 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
sham unx |
13 |
days |
remnant kidney |
101543 |
2602 |
| SD |
heart wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
days
| 8 |
|
1.33 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101619 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 7 |
|
69.0 |
mg |
3.4 |
9.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101600 |
2602 |
| SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
3.5 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
720 |
min |
|
98779 |
2160 |
| SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
days
| 8 |
|
1.94 |
g |
0.02 |
0.07 |
post excision weight measurement |
0.0 |
stz |
154 |
days |
|
99893 |
2358 |
| SD |
heart weight |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98.0 days
| 8 |
|
0.98 |
g |
0.05 |
0.14 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
99195 |
2278 |
| SD |
heart weight to body weight ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98.0 days
| 8 |
|
2.7 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
99199 |
2278 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
175.0 days
| 10 |
|
3.1 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
99206 |
2278 |
| SD |
lung weight |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
175.0 days
| 10 |
|
1.97 |
g |
0.06 |
0.19 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
99213 |
2278 |
| SD |
both kidneys wet weight as percentage of body weight |
control condition |
Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. |
kidney mass |
male |
180.0 days
| 5 |
|
0.6 |
% |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
|
|
|
100196 |
2439 |
| SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
days
| 8 |
|
2.14 |
g |
0.04 |
0.12 |
post excision weight measurement |
0.0 |
stz |
224 |
days |
|
99918 |
2358 |
| SD |
liver wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71.0 days-85.0 days |
6 |
|
4.06 |
g |
0.16 |
0.39 |
post excision weight measurement |
0.0 |
|
|
|
|
85201 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71.0 days-85.0 days |
6 |
|
0.85 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
|
|
|
85208 |
1602 |
| SD |
heart wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71.0 days-85.0 days |
6 |
|
0.37 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
|
|
|
85232 |
1602 |
| SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71.0 days-85.0 days |
6 |
|
0.4 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85236 |
1602 |
| SD |
heart wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71.0 days-85.0 days |
6 |
|
0.41 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
|
|
|
85237 |
1602 |
| SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
85.0 days-99.0 days |
6 |
|
0.41 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
|
|
|
85241 |
1602 |
| SD |
spleen wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
female |
71.0 days-85.0 days |
6 |
|
0.24 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85249 |
1602 |
| SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
85.0 days-99.0 days |
6 |
|
0.67 |
g |
0.01 |
0.03 |
post excision weight measurement |
0.0 |
|
|
|
|
85258 |
1602 |
| SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71.0 days-85.0 days |
6 |
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85266 |
1602 |
| SD |
brain wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71.0 days-85.0 days |
6 |
|
1.11 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
|
|
|
|
85262 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
male |
71.0 days-85.0 days |
6 |
|
0.02 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85269 |
1602 |
| SD |
adrenal gland wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
85.0 days-99.0 days |
6 |
|
0.04 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85276 |
1602 |
| SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
male |
71.0 days-85.0 days |
6 |
|
3.81 |
g |
0.09 |
0.21 |
post excision weight measurement |
0.0 |
|
|
|
|
85191 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
85.0 days-99.0 days |
6 |
|
0.88 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
|
|
|
85217 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
85.0 days-99.0 days |
6 |
|
0.74 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
|
|
|
85229 |
1602 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.6 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
98789 |
2160 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (between 120 and 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.3 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
5 |
days |
|
98792 |
2160 |
| SD |
adrenal gland weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 5 |
|
56.0 |
mg |
1.79 |
4.0 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
101561 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 5 |
|
60.0 |
mg |
3.13 |
7.0 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
|
101562 |
2602 |
| SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 7 |
|
1.91 |
g |
0.21 |
0.55 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
remnant kidney |
101580 |
2602 |
| SD |
heart wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
days
| 7 |
|
1.33 |
g |
0.07 |
0.19 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101588 |
2602 |
| SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 8 |
|
1.96 |
g |
0.16 |
0.44 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101613 |
2602 |
| SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 8 |
|
1.79 |
g |
0.12 |
0.35 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101614 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 8 |
|
71.0 |
mg |
1.41 |
4.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101627 |
2602 |
| SD |
adrenal gland weight |
sham surgical control condition (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 6 |
|
46.0 |
mg |
0.82 |
2.0 |
post excision weight measurement |
0.0 |
sham unx |
28 |
days |
|
101599 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 6 |
|
60.0 |
mg |
3.27 |
8.0 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101602 |
2602 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.5 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
98877 |
2160 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.8 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
98876 |
2160 |
| SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
3.3 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
360 |
min |
|
98777 |
2160 |
| SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
3.9 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
98781 |
2160 |
| SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 5 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
4.2 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
5 |
days |
|
98783 |
2160 |
| SD |
left kidney wet weight |
control condition |
Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. |
kidney mass |
male |
90.0 days
| 9 |
|
1.22 |
g |
0.05 |
0.15 |
post excision weight measurement |
0.0 |
|
|
|
|
101216 |
2582 |
| SD |
heart weight |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
98.0 days
| 8 |
|
1.55 |
g |
0.06 |
0.17 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
99196 |
2278 |
| SD |
heart weight |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175.0 days
| 10 |
|
2.23 |
g |
0.11 |
0.35 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
99198 |
2278 |
| SD |
heart weight to body weight ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175.0 days
| 10 |
|
4.8 |
g/kg |
0.3 |
0.95 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
99202 |
2278 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
98.0 days
| 8 |
|
2.1 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
99203 |
2278 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart left ventricle mass |
male |
98.0 days
| 8 |
|
3.1 |
mg/g |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
ACF |
28 |
days |
|
99204 |
2278 |
| SD |
heart right ventricle weight to body weight ratio |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart right ventricle mass |
male |
175.0 days
| 10 |
|
1.0 |
mg/g |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
99210 |
2278 |
| SD |
lung weight |
sham surgical control condition (for 28 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
98.0 days
| 8 |
|
1.46 |
g |
0.09 |
0.25 |
post excision weight measurement |
0.0 |
sham ACF |
28 |
days |
|
99211 |
2278 |
| SD |
liver weight as percentage of body weight |
2,3,7,8-tetrachlorodibenzo-p-dioxin (1000 ng/kg/d) (for 28 days) |
Harrill JA, et al., J Appl Toxicol. 2016 Jun;36(6):802-14. doi: 10.1002/jat.3211. Epub 2015 Aug 17. |
liver mass |
female |
84.0 days
| 10 |
|
5.07 |
% |
0.23 |
0.72 |
post excision weight measurement |
0.0 |
|
|
|
|
105725 |
3021 |
| SD |
liver wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
71.0 days-85.0 days |
6 |
|
4.2 |
g |
0.12 |
0.3 |
post excision weight measurement |
0.0 |
|
|
|
|
85202 |
1602 |
| SD |
liver wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
liver mass |
female |
85.0 days-99.0 days |
6 |
|
3.69 |
g |
0.16 |
0.38 |
post excision weight measurement |
0.0 |
|
|
|
|
85204 |
1602 |
| SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71.0 days-85.0 days |
6 |
|
0.89 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
|
|
|
85206 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
male |
71.0 days-85.0 days |
6 |
|
0.88 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
|
|
|
|
85207 |
1602 |
| SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71.0 days-85.0 days |
6 |
|
0.94 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
|
|
|
85212 |
1602 |
| SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
71.0 days-85.0 days |
6 |
|
0.37 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
|
|
|
85233 |
1602 |
| SD |
heart wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
male |
85.0 days-99.0 days |
6 |
|
0.33 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
|
|
|
85234 |
1602 |
| SD |
heart wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
heart mass |
female |
71.0 days-85.0 days |
6 |
|
0.42 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
|
|
|
85239 |
1602 |
| SD |
spleen wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71.0 days-85.0 days |
6 |
|
0.29 |
g |
0.08 |
0.19 |
post excision weight measurement |
0.0 |
|
|
|
|
85243 |
1602 |
| SD |
spleen wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
spleen mass |
male |
71.0 days-85.0 days |
6 |
|
0.21 |
g |
0.01 |
0.02 |
post excision weight measurement |
0.0 |
|
|
|
|
85245 |
1602 |
| SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
male |
71.0 days-85.0 days |
6 |
|
0.77 |
g |
0.02 |
0.05 |
post excision weight measurement |
0.0 |
|
|
|
|
85254 |
1602 |
| SD |
brain wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71.0 days-85.0 days |
6 |
|
1.1 |
g |
0.02 |
0.04 |
post excision weight measurement |
0.0 |
|
|
|
|
85260 |
1602 |
| SD |
brain wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
brain mass |
female |
71.0 days-85.0 days |
6 |
|
1.03 |
g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
|
|
|
85261 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
71.0 days-85.0 days |
6 |
|
0.04 |
g |
0.0 |
0.0 |
post excision weight measurement |
0.0 |
|
|
|
|
85273 |
1602 |
| SD |
adrenal gland wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
adrenal gland mass |
female |
85.0 days-99.0 days |
6 |
|
0.04 |
g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
|
|
|
85277 |
1602 |
| SD |
uterus wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71.0 days-85.0 days |
6 |
|
0.38 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
|
|
|
|
85287 |
1602 |
| SD |
both kidneys wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
71.0 days-85.0 days |
6 |
|
0.92 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
|
|
|
85215 |
1602 |
| SD |
both kidneys wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
kidney mass |
female |
85.0 days-99.0 days |
6 |
|
0.87 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
|
|
|
85216 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
male |
85.0 days-99.0 days |
6 |
|
0.64 |
g |
0.04 |
0.09 |
post excision weight measurement |
0.0 |
|
|
|
|
85223 |
1602 |
| SD |
both lungs wet weight |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71.0 days-85.0 days |
6 |
|
0.81 |
g |
0.05 |
0.13 |
post excision weight measurement |
0.0 |
|
|
|
|
85224 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71.0 days-85.0 days |
6 |
|
0.76 |
g |
0.02 |
0.06 |
post excision weight measurement |
0.0 |
|
|
|
|
85225 |
1602 |
| SD |
both lungs wet weight |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
lung mass |
female |
71.0 days-85.0 days |
6 |
|
0.8 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
|
|
|
85226 |
1602 |
| SD |
uterus wet weight |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
uterus mass |
female |
71.0 days-85.0 days |
6 |
|
0.28 |
g |
0.03 |
0.07 |
post excision weight measurement |
0.0 |
|
|
|
|
85285 |
1602 |
| SD |
heart left ventricle weight to body weight ratio |
sham surgical control condition (for 6 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.2 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
360 |
min |
|
98786 |
2160 |
| SD |
adrenal gland weight |
sham surgical control condition (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 6 |
|
51.0 |
mg |
1.63 |
4.0 |
post excision weight measurement |
0.0 |
sham unx |
13 |
days |
|
101559 |
2602 |
| SD |
adrenal gland weight |
unilateral nephrectomy (between 12 and 14 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
adrenal gland mass |
male |
days
| 11 |
|
63.0 |
mg |
1.21 |
4.0 |
post excision weight measurement |
0.0 |
unx |
13 |
days |
- |
101560 |
2602 |
| SD |
left kidney wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
kidney mass |
male |
days
| 6 |
|
2.03 |
g |
0.2 |
0.48 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
remnant kidney |
101582 |
2602 |
| SD |
heart wet weight |
unilateral nephrectomy (for 28 days) then enalapril (50 mg/l) (for 28 days) and losartan (180 mg/l) (for 28 days) and aldosterone (35 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
heart mass |
male |
days
| 6 |
|
1.28 |
g |
0.05 |
0.12 |
post excision weight measurement |
0.0 |
unx |
28 |
days |
|
101590 |
2602 |
| SD |
heart left ventricle weight to body weight ratio |
artificial aortocaval fistula (for 2 days) then vehicle control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart left ventricle mass |
male |
days
| 6 |
g/g*103 |
2.6 |
mg/g |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
ACF |
2 |
days |
|
98874 |
2160 |
| SD |
heart weight to body weight ratio |
sham surgical control condition (for 2 days) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
3.3 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
2 |
days |
|
98782 |
2160 |
| SD |
heart weight to body weight ratio |
sham surgical control condition (for 12 hours) |
Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. |
heart mass |
male |
days
| 6 |
g/g*103 |
3.4 |
g/kg |
0.1 |
0.24 |
post excision weight measurement |
1.0 |
sham ACF |
720 |
min |
|
98780 |
2160 |
| SD |
left kidney wet weight |
streptozotocin (60 mg/kg) then insulin then Moexipril (30-35 mg/kg/d) (for 112 days) |
Perico N, et al., J Am Soc Nephrol. 1994 Oct;5(4):1139-46. |
kidney mass |
male |
days
| 8 |
|
1.9 |
g |
0.04 |
0.1 |
post excision weight measurement |
0.0 |
stz |
154 |
days |
|
99894 |
2358 |
| SD |
heart weight to body weight ratio |
sham surgical control condition (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
heart mass |
male |
175.0 days
| 10 |
|
2.7 |
g/kg |
0.1 |
0.32 |
post excision weight measurement |
0.0 |
sham ACF |
105 |
days |
|
99201 |
2278 |
| SD |
lung weight |
artificial aortocaval fistula (for 105 days) |
Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. |
lung mass |
male |
175.0 days
| 10 |
|
2.44 |
g |
0.11 |
0.35 |
post excision weight measurement |
0.0 |
ACF |
105 |
days |
|
99214 |
2278 |