Phenominer Database Results (111 results)

 

Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 241.17 uV 16.89 41.37 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108517 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 57.63 uV 8.8 21.56 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108520 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 11.45 uV 3.56 9.42 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108537 3123
Hsd:SD scotopic A wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 173.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic a-wave ERG 108654 3128
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 34 days 8 20.0 uV 20.0 56.57 electroretinography cornea 0.0 subretinal injection 14 days adenovirus a-wave amplitude ERG 108375 3121
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 8.81 uV 1.84 4.51 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108392 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 25.3 uV 2.85 6.98 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108399 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 161.92 uV 30.48 74.66 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108401 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 94.57 uV 13.87 33.97 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108424 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 243.17 uV 24.11 59.06 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108427 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 201.67 uV 18.19 44.56 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108444 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 26.68 uV 7.67 18.79 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108447 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 190.83 uV 21.76 53.3 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108450 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 87.05 uV 8.87 29.42 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108472 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 206.0 uV 11.62 28.46 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108499 3123
Hsd:SD scotopic A wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 154.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic a-wave ERG 108648 3128
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 5.86 uV 0.76 2.01 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108536 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 27.22 uV 4.74 12.54 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108539 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 33.73 uV 9.28 24.55 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108540 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 15.31 uV 2.98 7.88 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108549 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 16.12 uV 3.84 9.41 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108512 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 96.3 uV 10.3 23.03 electroretinography cornea 0.0 plasmid delivery 37 days pVAX2-rGDNF scotopic a-wave ERG 108725 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 29.7 uV 11.3 25.27 electroretinography cornea 0.0 plasmid delivery 59 days pVAX2-rGDNF scotopic a-wave ERG 108729 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 78.43 uV 13.51 33.09 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108394 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 118.43 uV 17.52 42.92 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108396 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 9.73 uV 2.39 5.85 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108398 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 109.52 uV 22.74 55.7 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108400 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 23.02 uV 5.24 12.84 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108417 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 6.38 uV 1.4 3.43 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108440 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 155.28 uV 13.68 33.51 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108443 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 8.38 uV 1.81 4.43 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108446 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 78.77 uV 13.41 32.85 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108448 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 146.78 uV 16.49 40.39 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108449 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 12.43 uV 2.29 7.6 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108470 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 18.46 uV 3.3 10.94 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108471 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 144.39 uV 13.24 43.91 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108473 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 80.6 uV 11.3 27.68 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108490 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 62 days 5 9.7 uV 9.9 22.14 electroretinography cornea 0.0 subretinal injection 42 days adenovirus a-wave amplitude ERG 108387 3121
RCS/N scotopic A wave amplitude of ERG waveform lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. rod electrophysiology trait not specified 60 days 3 18.3 uV 4.79 8.3 electroretinography cornea 0.0 lens puncture 30 days scotopic a-wave ERG 108566 3124
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 31.22 uV 8.16 21.59 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108551 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 24.5 uV 4.9 10.96 electroretinography cornea 0.0 plasmid delivery 71 days scotopic a-wave ERG 108734 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 19.36 uV 3.48 8.52 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108513 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 16.61 uV 4.28 10.48 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108518 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 89.88 uV 11.06 27.09 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108521 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 124.83 uV 7.26 17.78 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108522 3123
Hsd:SD scotopic A wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 203.0 uV electroretinography cornea 0.0 0 scotopic a-wave ERG 108655 3128
RCS/N scotopic A wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 16.0 uV 6.94 17.0 electroretinography cornea 0.0 AAV8 injection 60 days contralateral control eye scotopic a-wave amplitude ERG 108681 3129
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) and gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 23.8 uV 1.9 3.29 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic a-wave ERG 108746 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 11.22 uV 1.07 2.62 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108416 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 95.25 uV 7.15 17.51 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108418 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 240.67 uV 14.84 36.35 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108421 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 25.21 uV 4.23 10.36 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108441 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 11.68 uV 2.42 8.03 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108465 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 104.17 uV 12.63 41.89 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108467 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 118.51 uV 12.59 41.76 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108468 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 24.73 uV 6.11 14.97 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108489 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 119.33 uV 19.43 47.59 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108491 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 13.98 uV 3.06 7.5 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108494 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 145.83 uV 14.32 35.08 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108497 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 34 days 8 13.0 uV 13.0 36.77 electroretinography 0.0 0 untreated control electrical activity measurement of retina (CMO:0003653)/A wave 108374 3121
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 48 days 5 17.0 uV 5.0 11.18 electroretinography 0.0 0 untreated control a-wave amplitude ERG 108380 3121
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the lin-28 homolog B gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 34 days 8 34.0 uV 26.0 73.54 electroretinography cornea 0.0 subretinal injection 14 days adenovirus a-wave amplitude ERG 108376 3121
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the lin-28 homolog B gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 48 days 5 27.0 uV 22.0 49.19 electroretinography cornea 0.0 subretinal injection 28 days adenovirus a-wave amplitude ERG 108382 3121
Hsd:SD scotopic A wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 195.0 uV electroretinography cornea 0.0 0 scotopic a-wave ERG 108649 3128
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 172.6 uV 20.12 49.28 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108515 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 19.05 uV 3.75 9.92 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108550 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 17.1 uV 3.2 7.16 electroretinography cornea 0.0 plasmid delivery 71 days pVAX2-rGDNF scotopic a-wave ERG 108733 3131
Hsd:SD scotopic A wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 142.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic a-wave ERG 108642 3128
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 60.2 uV 8.5 19.01 electroretinography cornea 0.0 plasmid delivery 37 days scotopic a-wave ERG 108726 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 26.7 uV 2.7 4.68 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic a-wave ERG 108747 3131
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 20.9 uV 3.7 6.41 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic a-wave ERG 108748 3131
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 138.93 uV 9.28 22.73 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108523 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 48 days 5 17.0 uV 18.0 40.25 electroretinography cornea 0.0 subretinal injection 28 days adenovirus a-wave amplitude ERG 108381 3121
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 62 days 5 8.9 uV 9.9 22.14 electroretinography 0.0 0 untreated control a-wave amplitude ERG 108386 3121
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 15.03 uV 4.72 11.56 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108393 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 108.63 uV 17.19 42.11 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108395 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 143.17 uV 20.27 49.65 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108397 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 224.32 uV 34.64 84.85 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108403 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 162.07 uV 9.02 22.09 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108419 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 202.5 uV 12.47 30.55 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108420 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 27.7 uV 4.72 11.56 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108423 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 218.83 uV 22.09 54.11 electroretinography cornea 0.0 subretinal injection 30 min pbs a-wave amplitude ERG 108451 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 71.37 uV 8.23 27.3 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108466 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 170.91 uV 16.52 54.79 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108474 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 201.55 uV 19.9 66.0 electroretinography cornea 0.0 subretinal injection 2 days pbs a-wave amplitude ERG 108475 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 15.46 uV 4.1 10.04 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108488 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 188.33 uV 15.56 38.11 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108493 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 100.23 uV 12.78 31.3 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108496 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 178.0 uV 12.3 30.13 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108498 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 112.85 uV 11.14 27.29 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108514 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 3.13 uV 1.81 4.79 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108548 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 24.79 uV 7.82 20.69 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108552 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer of the lin-28 homolog B gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 62 days 5 11.0 uV 12.0 26.83 electroretinography cornea 0.0 subretinal injection 42 days adenovirus a-wave amplitude ERG 108388 3121
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 190.68 uV 32.08 78.58 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa a-wave amplitude ERG 108402 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 7.62 uV 1.56 3.82 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108422 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 149.83 uV 9.83 24.08 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108425 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 202.33 uV 17.65 43.23 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa a-wave amplitude ERG 108426 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 88.5 uV 12.52 30.67 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108442 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 216.67 uV 19.46 47.67 electroretinography cornea 0.0 subretinal injection 30 min CHPG a-wave amplitude ERG 108445 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 5.17 uV 1.18 3.91 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108464 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 137.5 uV 12.91 42.82 electroretinography cornea 0.0 subretinal injection 2 days CHPG a-wave amplitude ERG 108469 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 166.85 uV 19.57 47.94 electroretinography cornea 0.0 subretinal injection 10 days CHPG a-wave amplitude ERG 108492 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 30.66 uV 9.93 24.32 electroretinography cornea 0.0 subretinal injection 10 days pbs a wave amplitude ERG 108495 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 208.5 uV 14.36 35.17 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP a-wave amplitude ERG 108516 3123
RCS-rdy+ p+/LavRrrc scotopic A wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 16.11 uV 3.41 8.35 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs a-wave amplitude ERG 108519 3123
Hsd:SD scotopic A wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 202.0 uV electroretinography cornea 0.0 0 scotopic a-wave ERG 108643 3128
RCS/N scotopic A wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 175.0 uV 14.7 36.0 electroretinography cornea 0.0 AAV8 injection 60 days treated eye scotopic a-wave amplitude ERG 108680 3129
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 18.53 uV 4.77 12.63 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108538 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 36.49 uV 10.37 27.44 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108541 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 31.96 uV 9.73 25.74 electroretinography cornea 0.0 subretinal injection 4 days MPEP a-wave amplitude ERG 108553 3123
RCS-p+/LavRrrc scotopic A wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 23.1 uV 4.0 8.94 electroretinography cornea 0.0 plasmid delivery 59 days scotopic a-wave ERG 108730 3131