Phenominer Database Results (125 results)

 

Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
Hsd:SD scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 456.0 uV electroretinography cornea 0.0 0 scotopic b-wave ERG 108641 3128
Hsd:SD scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 4 338.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic b-wave ERG 108640 3128
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 114.0 uV 16.1 36.0 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108703 3131
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 411.83 uV 43.52 106.6 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108408 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 62.22 uV 18.42 45.12 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108410 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 652.5 uV 65.65 160.81 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108415 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 373.83 uV 17.47 42.79 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108429 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 437.0 uV 33.32 81.62 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108431 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 594.5 uV 24.04 58.89 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108433 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 598.67 uV 39.64 97.1 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108463 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 270.09 uV 34.35 113.93 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108477 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 466.45 uV 51.69 171.44 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108484 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 518.55 uV 54.69 181.39 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108485 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 385.17 uV 61.99 151.84 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108501 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 429.5 uV 66.11 161.94 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108502 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 101.1 uV 20.75 50.83 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108506 3123
Hsd:SD scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (4 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 387.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic b-wave ERG 108646 3128
Hsd:SD scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 488.0 uV electroretinography cornea 0.0 0 scotopic b-wave ERG 108647 3128
RCS/LavRrrc scotopic B wave amplitude of ERG waveform human periodontal ligament-derived stem cells (0.2 x 10E6 cells) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 49 days 4 204.9 uV 52.13 104.26 electroretinography retina 0.0 hPDLSC transplant 28 days 109857 3157
RCS/LavRrrc scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 49 days 4 13.93 uV 1.49 2.98 electroretinography retina 0.0 untreated control 28 days 109858 3157
RCS/LavRrrc scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 49 days 4 29.44 uV 7.44 14.87 electroretinography retina 0.0 pbs vehicle injection 28 days 109859 3157
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108728 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 7.44 uV 1.43 3.78 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108542 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 251.29 uV 19.14 50.64 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108547 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 83.0 uV 7.0 15.65 electroretinography cornea 0.0 plasmid delivery 71 days pVAX2-rGDNF scotopic b-wave ERG 108735 3131
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 119.08 uV 22.02 53.94 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108524 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 739.67 uV 44.42 108.81 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108527 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 748.17 uV 64.77 158.65 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108528 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 419.0 uV 21.83 53.47 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108533 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 423.33 uV 25.5 62.46 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108534 3123
Hsd:SD scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (40 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 397.0 uV electroretinography cornea 0.0 subretinal injection 30 days scotopic b-wave ERG 108652 3128
RCS/N scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 61.0 uV 19.6 48.0 electroretinography cornea 0.0 AAV8 injection 60 days contralateral control eye scotopic b-wave amplitude ERG 108683 3129
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 24.7 uV 13.8 30.86 electroretinography cornea 0.0 59 days control for age matched plasmid injection scotopic b-wave ERG 108704 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) and gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 231.0 uV 5.0 8.66 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2 scotopic b-wave ERG 108749 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (15 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 199.0 uV 17.0 29.44 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic b-wave ERG 108750 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 62 days 5 13.0 uV 17.0 38.01 electroretinography 0.0 0 untreated control b-wave amplitude ERG 108389 3121
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 327.83 uV 16.41 40.2 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108405 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 532.5 uV 62.77 153.75 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108412 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 440.0 uV 43.67 106.97 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108454 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 579.0 uV 50.99 124.9 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108457 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 358.5 uV 35.71 87.47 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108459 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 584.5 uV 38.15 93.45 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108462 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 351.91 uV 47.74 158.34 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108479 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 389.91 uV 52.11 172.83 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108480 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 410.45 uV 48.4 160.52 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108483 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 71.98 uV 18.54 45.41 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108500 3123
Hsd:SD scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus (5 cd/m2) Conlon TJ, et al., Hum Gene Ther Clin Dev. 2013 Mar;24(1):23-8. doi: 10.1089/humc.2013.037. Epub 2013 Apr 3. rod electrophysiology trait both 0 days 9 491.0 uV electroretinography cornea 0.0 0 scotopic b-wave ERG 108653 3128
RCS/LavRrrc scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 35 days 4 95.22 uV 16.19 32.38 electroretinography retina 0.0 pbs vehicle injection 14 days 109856 3157
RCS/LavRrrc scotopic B wave amplitude of ERG waveform vehicle control condition (2 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 77 days 4 13.01 uV 1.85 3.69 electroretinography retina 0.0 pbs vehicle injection 56 days 109862 3157
RCS/N scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (2.5 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 62 days 6 500.0 uV 61.24 150.0 electroretinography cornea 0.0 AAV8 injection 60 days treated eye scotopic b-wave amplitude ERG 108682 3129
RCS/N scotopic B wave amplitude of ERG waveform lensotomy then controlled exposure to darkness (for 1 days) then visible light stimulus (100 cd x s/m2) Heiduschka P, et al., ISRN Ophthalmol. 2013 Sep 19;2013:814814. doi: 10.1155/2013/814814. eCollection 2013. rod electrophysiology trait not specified 60 days 3 30.5 uV 7.51 13.0 electroretinography cornea 0.0 lens puncture 30 days scotopic b-wave ERG 108567 3124
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 192.0 uV 14.42 38.15 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108545 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 94.13 uV 15.33 40.56 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108556 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 179.49 uV 20.75 54.9 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108559 3123
RCS/LavRrrc scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 77 days 4 12.57 uV 1.42 2.84 electroretinography retina 0.0 untreated control 56 days 109861 3157
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 47.53 uV 9.4 23.03 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108530 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 65.42 uV 13.87 33.97 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108428 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 382.17 uV 30.52 74.76 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108430 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 519.33 uV 29.94 73.34 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108432 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 570.67 uV 21.08 51.64 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108438 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 621.67 uV 35.23 86.3 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108439 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 514.67 uV 47.85 117.21 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108455 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 49.97 uV 12.07 29.57 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108458 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 438.83 uV 24.27 59.45 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108460 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 334.55 uV 43.36 143.81 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108478 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 410.09 uV 45.37 150.48 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108481 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 605.83 uV 62.69 153.56 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108505 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 393.0 uV 65.49 160.42 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108507 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 34 days 8 45.0 uV 42.0 118.79 electroretinography 0.0 0 untreated control b-wave amplitude ERG 108377 3121
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 62 days 5 14.0 uV 17.0 38.01 electroretinography cornea 0.0 subretinal injection 42 days adenovirus b-wave amplitude ERG 108390 3121
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the lin-28 homolog B gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 62 days 5 34.0 uV 27.0 60.37 electroretinography cornea 0.0 subretinal injection 42 days adenovirus b-wave amplitude ERG 108391 3121
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 51.68 uV 12.61 30.89 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108404 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 475.0 uV 41.0 91.68 electroretinography cornea 0.0 plasmid delivery 37 days pVAX2-rGDNF scotopic b-wave ERG 108727 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 135.0 uV 38.0 84.97 electroretinography cornea 0.0 plasmid delivery 59 days pVAX2-rGDNF scotopic b-wave ERG 108731 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 159.83 uV 21.35 56.49 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108558 3123
RCS/LavRrrc scotopic B wave amplitude of ERG waveform controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 35 days 4 61.63 uV 15.09 30.17 electroretinography retina 0.0 untreated control 14 days 109855 3157
RCS/LavRrrc scotopic B wave amplitude of ERG waveform human periodontal ligament-derived stem cells (0.2 x 10E6 cells) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 77 days 4 45.89 uV 3.23 6.45 electroretinography retina 0.0 hPDLSC transplant 56 days 109860 3157
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 455.17 uV 35.54 87.05 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108535 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 87 days 5 110.0 uV 14.0 31.3 electroretinography cornea 0.0 plasmid delivery 71 days scotopic b-wave ERG 108736 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) and gene transfer of the rat GDNF gene using the plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 70 days 3 144.0 uV 29.0 50.23 electroretinography cornea 0.0 plasmid delivery 54 days pVAX2-rGDNF scotopic b-wave ERG 108751 3131
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 570.67 uV 53.5 131.05 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108510 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 625.0 uV 55.4 135.7 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108511 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 584.5 uV 55.51 135.97 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108525 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 644.33 uV 50.52 123.75 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108526 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 354.0 uV 16.81 41.18 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108531 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 371.67 uV 28.82 70.59 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108406 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 391.5 uV 33.43 81.89 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108407 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 42.97 uV 8.99 22.02 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108434 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 399.83 uV 37.74 92.44 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108436 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 56.16 uV 17.2 42.13 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108452 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 381.17 uV 37.99 93.06 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108453 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 587.83 uV 53.2 130.31 electroretinography cornea 0.0 subretinal injection 30 min CHPG b-wave amplitude ERG 108456 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 607.73 uV 58.9 195.35 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108487 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 485.67 uV 73.15 179.18 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108503 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 511.83 uV 65.06 159.36 electroretinography cornea 0.0 subretinal injection 10 days CHPG b-wave amplitude ERG 108504 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 587.17 uV 49.54 121.35 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108509 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the lin-28 homolog B gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 48 days 5 110.0 uV 40.0 89.44 electroretinography cornea 0.0 subretinal injection 28 days adenovirus b-wave amplitude ERG 108385 3121
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 75 days 5 114.0 uV 16.0 35.78 electroretinography cornea 0.0 plasmid delivery 59 days scotopic b-wave ERG 108732 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 145.24 uV 12.56 33.23 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108544 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 32.75 uV 13.42 35.51 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108555 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 131.7 uV 16.13 42.68 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108557 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 48 days 5 51.0 uV 33.0 73.79 electroretinography cornea 0.0 subretinal injection 28 days adenovirus b-wave amplitude ERG 108384 3121
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 430.17 uV 45.59 111.67 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108409 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 460.67 uV 47.48 116.3 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108411 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 592.83 uV 68.9 168.77 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108413 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 638.33 uV 68.2 167.06 electroretinography cornea 0.0 subretinal injection 7 days dl-aaa b-wave amplitude ERG 108414 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 356.17 uV 23.35 57.2 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108435 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 497.33 uV 42.65 104.47 electroretinography cornea 0.0 subretinal injection 10 days dl-aaa b-wave amplitude ERG 108437 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.02 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 516.5 uV 29.8 72.99 electroretinography cornea 0.0 subretinal injection 30 min pbs b-wave amplitude ERG 108461 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-Chloro-5-hydroxyphenylglycine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 44.02 uV 13.47 44.67 electroretinography cornea 0.0 subretinal injection 2 days CHPG b-wave amplitude ERG 108476 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 56.72 uV 16.42 54.46 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108482 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 11 567.73 uV 56.78 188.32 electroretinography cornea 0.0 subretinal injection 2 days pbs b wave amplitude ERG 108486 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 533.17 uV 67.99 166.54 electroretinography cornea 0.0 subretinal injection 10 days pbs b wave amplitude ERG 108508 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (1 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 800.0 uV 67.71 165.85 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + MPEP b-wave amplitude ERG 108529 3123
RCS-rdy+ p+/LavRrrc scotopic B wave amplitude of ERG waveform DL-α-aminoadipate (70 ug/ul) and phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 0 days 6 382.33 uV 22.98 56.29 electroretinography cornea 0.0 subretinal injection 2 days dl-aaa + pbs b-wave amplitude ERG 108532 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer using empty plasmid vector pVAX2 (30 ug) then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 352.0 uV 26.0 58.14 electroretinography cornea 0.0 plasmid delivery 37 days scotopic b-wave ERG 108701 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 1 days) then visible light stimulus (3 cd x s/m2) Touchard E, et al., Gene Ther. 2012 Sep;19(9):886-98. doi: 10.1038/gt.2011.154. Epub 2011 Oct 13. rod electrophysiology trait both 53 days 5 186.0 uV 23.8 53.22 electroretinography cornea 0.0 37 days control for age matched plasmid injection scotopic b-wave ERG 108702 3131
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the enhanced green fluorescent protein gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 34 days 8 39.0 uV 23.0 65.05 electroretinography cornea 0.0 subretinal injection 14 days adenovirus b-wave amplitude ERG 108378 3121
RCS/N scotopic B wave amplitude of ERG waveform gene transfer of the rat MER proto-oncogene, tyrosine kinase gene using an adenovirus vector (21.6 x 10E8 vg) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.01 cd x s/m2) Deng WT, et al., Invest Ophthalmol Vis Sci. 2012 Apr 6;53(4):1895-904. doi: 10.1167/iovs.11-8831. rod electrophysiology trait not specified 242 days 4 223.0 uV 28.0 56.0 electroretinography cornea 0.0 AAV8 injection 240 days treated eye scotopic b-wave amplitude ERG 108684 3129
RCS/LavRrrc scotopic B wave amplitude of ERG waveform human periodontal ligament-derived stem cells (0.2 x 10E6 cells) then controlled exposure to darkness (for 12 hours) then visible light stimulus Huang L, et al., Stem Cell Res Ther. 2017 Dec 22;8(1):290. doi: 10.1186/s13287-017-0731-y. rod electrophysiology trait not specified 35 days 4 143.41 uV 12.18 24.35 electroretinography retina 0.0 hPDLSC transplant 14 days 109854 3157
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform gene transfer of the lin-28 homolog B gene using an adenovirus vector (5250000 PFU) then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 34 days 8 79.0 uV 43.0 121.62 electroretinography cornea 0.0 subretinal injection 14 days adenovirus b-wave amplitude ERG 108379 3121
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform control condition then controlled exposure to darkness (for 12 hours) Tao Z, et al., Oncotarget. 2016 Aug 2;7(31):49368-49383. doi: 10.18632/oncotarget.10343. rod electrophysiology trait both 48 days 5 48.0 uV 26.0 58.14 electroretinography 0.0 0 untreated control b-wave amplitude ERG 108383 3121
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-2.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 83.4 uV 14.8 39.16 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108543 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform 2-methyl-6-(phenylethynyl)pyridine (200 umol) then controlled exposure to darkness (for 12 hours) then visible light stimulus (0.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 233.29 uV 18.61 49.24 electroretinography cornea 0.0 subretinal injection 4 days pbs a wave amplitude ERG 108546 3123
RCS-p+/LavRrrc scotopic B wave amplitude of ERG waveform phosphate buffered saline (4 ul) then controlled exposure to darkness (for 12 hours) then visible light stimulus (-4.5 log(cd x m/s2)) Dai J, et al., Sci Rep. 2017 Jun 14;7(1):3546. doi: 10.1038/s41598-017-03702-z. rod electrophysiology trait both 39 days 7 10.28 uV 1.69 4.47 electroretinography cornea 0.0 subretinal injection 4 days pbs b-wave amplitude ERG 108554 3123