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# of AnimalsPhenotypeStrainSexValueUnitsConditionsRecord IDCondition 1aCondition 1bCondition 1cCondition 2aCondition 2bCondition 2cCondition 3Condition 4Condition 5
10logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.4controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84641controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
6logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.2controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84642controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
6logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.2controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84643controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.2controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours) then acetylcholine (0.001-9.5 umol/l) 84644controlled carbohydrate content diet (53 %) (for 91 days)controlled fat content diet (14 %) (for 91 days)controlled protein content diet (33 %) (for 91 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) (for 0.2 hours)acetylcholine (0.001-9.5 umol/l)
8logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.3controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (0.001-9.5 umol/l) 84645controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (0.001-9.5 umol/l)
6logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.6controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (0.001-9.5 umol/l) 84646controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (0.001-9.5 umol/l)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.7controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (2 umol/l) then NG-nitroarginine methyl ester (100 umol/l) then acetylcholine (0.001-9.5 umol/l) 84647controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (2 umol/l) NG-nitroarginine methyl ester (100 umol/l) acetylcholine (0.001-9.5 umol/l)
4logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-7.1controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then phenylephrine (2 umol/l) then acetylcholine (0.001-9.5 umol/l) 84640controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)phenylephrine (2 umol/l) acetylcholine (0.001-9.5 umol/l)
4logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.31controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then phenylephrine (1 umol/l) then acetylcholine (0-95 umol/l) 84664controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)phenylephrine (1 umol/l) acetylcholine (0-95 umol/l)
7logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.33controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (0-95 umol/l) 84665controlled carbohydrate content diet (53 %) (for 63 days)controlled fat content diet (14 %) (for 63 days)controlled protein content diet (33 %) (for 63 days)controlled carbohydrate content diet (69 %) (for 28 days)controlled fat content diet (12 %) (for 28 days)controlled protein content diet (19 %) (for 28 days)phenylephrine (1 umol/l) acetylcholine (0-95 umol/l)
4logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.49controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) then phenylephrine (1 umol/l) then acetylcholine (0-95 umol/l) 84666controlled carbohydrate content diet (69 %) (for 91 days)controlled fat content diet (12 %) (for 91 days)controlled protein content diet (19 %) (for 91 days)phenylephrine (1 umol/l) acetylcholine (0-95 umol/l)
5logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)SS/HsdMcwiCrlmale-6.49controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) then phenylephrine (1 umol/l) then acetylcholine (0.001-95 umol/l) 84667controlled carbohydrate content diet (69 %) (for 63 days)controlled fat content diet (12 %) (for 63 days)controlled protein content diet (19 %) (for 63 days)controlled carbohydrate content diet (53 %) (for 28 days)controlled fat content diet (14 %) (for 28 days)controlled protein content diet (33 %) (for 28 days)phenylephrine (1 umol/l) acetylcholine (0.001-95 umol/l)