SS/Jr |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days) |
Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
58.0 |
mmHg |
0.38 |
1.2 |
radiotelemetry |
|
345600 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
aveerage of 4-hour interval averages over 4 days |
12922 |
313 |
SS-Nppbem2Mcwi+/+ |
pulse pressure |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
168 days
| 5 |
|
45.0 |
mmHg |
8.0 |
17.89 |
intra-aortic abdominal radiotelemetry via abdominal aorta cannulation |
|
0.0 |
0 |
|
|
99539 |
2319 |
SS-Nppbem2Mcwi+/+ |
pulse pressure |
control condition (for 222 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
222 days
| 3 |
|
52.0 |
mmHg |
1.0 |
1.73 |
intra-aortic abdominal radiotelemetry via abdominal aorta cannulation |
|
0.0 |
0 |
|
|
99541 |
2319 |
SS-Nppbem2Mcwi-/- |
pulse pressure |
control condition (for 222 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
222 days
| 3 |
|
57.0 |
mmHg |
4.0 |
6.93 |
intra-aortic abdominal radiotelemetry via abdominal aorta cannulation |
|
0.0 |
0 |
|
|
99542 |
2319 |
SS.SHR-(D9Mco110-D9Mco124)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
7 |
serial mean |
42.2 |
mmHg |
0.22 |
0.58 |
radiotelemetry |
|
0.0 |
0 |
|
|
97967 |
1958 |
SS.LEW-(D1Mco55-D1Wox6)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) |
Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
48.0 |
mmHg |
2.0 |
6.32 |
radiotelemetry |
|
345600.0 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 24 hour |
96964 |
1778 |
SS/JrTol |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) |
Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
41.0 |
mmHg |
5.0 |
15.81 |
radiotelemetry |
|
345600.0 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 24 hour |
97026 |
1778 |
LH/Mav |
pulse pressure |
control condition |
Dubay C, et al., Nat Genet 1993 Apr;3(4):354-7 |
arterial blood pressure trait |
male |
203 days-217 days |
16 |
serial mean |
43.3 |
mmHg |
|
|
vascular indwelling catheter method |
abdominal aorta |
10800 |
0 |
|
|
11650 |
111 |
WKY/Gcrc |
pulse pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
124 days-128 days |
6 |
continuous mean |
50.0 |
mmHg |
1.76 |
4.3 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
0 |
|
|
11630 |
109 |
SS/JrHsd |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
male |
108 days-112 days |
8 |
|
57.1 |
mmHg |
0.4 |
1.13 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
0 |
|
|
70504 |
1458 |
SS.SR-(rs106870553-rs63922710)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
51.84 |
mmHg |
1.4 |
4.43 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
0 |
|
|
70569 |
1458 |
SS/JrTol |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) |
Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
58.0 |
mmHg |
4.0 |
12.65 |
radiotelemetry |
|
345600.0 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 24 hour |
97027 |
1778 |
SS.SHR-(D9Mco110-D9Got111)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
6 |
serial mean |
38.2 |
mmHg |
6.67 |
16.34 |
radiotelemetry |
|
0.0 |
0 |
|
|
97970 |
1958 |
SS.LEW-(D1Rat200-D1Mco136)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) |
Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
49.0 |
mmHg |
3.0 |
9.49 |
radiotelemetry |
|
345600.0 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 24 hour |
96962 |
1778 |
SS/Jr |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
6 |
serial mean |
53.4 |
mmHg |
1.9 |
4.65 |
radiotelemetry |
|
0.0 |
0 |
|
|
97994 |
1958 |
SS/Jr |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
6 |
serial mean |
53.4 |
mmHg |
1.9 |
4.65 |
radiotelemetry |
|
0.0 |
0 |
|
|
98196 |
1958 |
WKY/Gcrc |
pulse pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
124 days-128 days |
6 |
continuous mean |
42.6 |
mmHg |
1.1 |
2.7 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
0 |
|
|
11631 |
109 |
SS.LEW-(D1Rat211-D1Rat18)/Mco |
pulse pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
49.0 |
mmHg |
0.74 |
2.09 |
intra-aortic abdominal radiotelemetry |
|
10 |
0 |
|
average of 24 hr |
65500 |
611 |
SS.SR-(rs65785750-rs13452155)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
10 |
|
54.11 |
mmHg |
0.4 |
1.26 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
0 |
|
|
70361 |
1358 |
SS/JrTol |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) |
Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
58.0 |
mmHg |
4.0 |
12.65 |
radiotelemetry |
|
345600.0 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 24 hour |
96961 |
1778 |
SS.LEW-(D1Mco134-D1Wox6)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) |
Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
37.0 |
mmHg |
9.0 |
28.46 |
radiotelemetry |
|
345600.0 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
average of 24 hour |
96963 |
1778 |
SS/Jr |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
8 |
serial mean |
50.4 |
mmHg |
2.35 |
6.65 |
radiotelemetry |
|
0.0 |
0 |
|
|
97993 |
1958 |
SS-Nppbem2Mcwi+/+ |
pulse pressure |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
84 days
| 2 |
|
36.0 |
mmHg |
1.0 |
1.41 |
intra-aortic abdominal radiotelemetry via abdominal aorta cannulation |
|
0.0 |
0 |
|
|
99537 |
2319 |
SS/Jr |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
6 |
serial mean |
53.4 |
mmHg |
1.9 |
4.65 |
radiotelemetry |
|
0.0 |
0 |
|
|
98195 |
1958 |
SS.SR-(rs65785750-rs106808193)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
8 |
|
52.03 |
mmHg |
1.4 |
3.96 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
0 |
|
|
70362 |
1358 |
SHRSP/Gcrc |
pulse pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
124 days-128 days |
6 |
continuous mean |
57.1 |
mmHg |
1.55 |
3.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
0 |
|
|
11629 |
109 |
WKY/Gcrc |
pulse pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
137 days-140 days |
6 |
continuous mean |
52.9 |
mmHg |
1.51 |
3.7 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
0 |
|
|
11639 |
109 |
WKY/Gcrc |
pulse pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
continuous mean |
45.9 |
mmHg |
1.14 |
2.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
0 |
|
|
11640 |
109 |
SS/Jr |
pulse pressure |
controlled sodium content diet (2 %) (between 34 and 38 days) |
Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. |
arterial blood pressure trait |
male |
73 days-80 days |
8 |
|
52.0 |
mmHg |
3.4 |
9.62 |
intra-aortic abdominal radiotelemetry |
|
10 |
0 |
|
average of 24 hr |
65495 |
611 |
SHRSP/Gcrc |
pulse pressure |
control condition |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
male |
124 days-128 days |
7 |
continuous mean |
69.6 |
mmHg |
1.06 |
2.8 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
0 |
|
|
11628 |
109 |
SS.LEW-(D1Mco36-D1Mco101)/Mco |
pulse pressure |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days) |
Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. |
arterial blood pressure trait |
male |
73 days-75 days |
10 |
|
48.0 |
mmHg |
0.23 |
0.73 |
radiotelemetry |
|
345600 |
0 |
C-40 transmitter (Data Sciences International, St. Paul, MN) |
aveerage of 4-hour interval averages over 4 days |
12923 |
313 |
SS/JrHsd |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. |
arterial blood pressure trait |
female |
108 days-112 days |
9 |
|
54.74 |
mmHg |
0.8 |
2.4 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
0 |
|
|
70360 |
1358 |
SS/Jr |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
7 |
serial mean |
59.3 |
mmHg |
0.55 |
1.46 |
radiotelemetry |
|
0.0 |
0 |
|
|
97992 |
1958 |
LN/Mav |
pulse pressure |
control condition |
Dubay C, et al., Nat Genet 1993 Apr;3(4):354-7 |
arterial blood pressure trait |
male |
203 days-217 days |
14 |
serial mean |
55.6 |
mmHg |
|
|
vascular indwelling catheter method |
abdominal aorta |
10800 |
0 |
|
|
11649 |
111 |
SS.SR-(D2Rat352-rs63922710)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
female |
108 days-112 days |
6 |
|
50.0 |
mmHg |
1.0 |
2.45 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
0 |
|
|
70561 |
1458 |
SS.SHR-(D9Mco115-D9Mco124)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
6 |
serial mean |
40.3 |
mmHg |
7.06 |
17.29 |
radiotelemetry |
|
0.0 |
0 |
|
|
97971 |
1958 |
SS.SHR-(D9Mco110-D9Mco121)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
8 |
serial mean |
44.1 |
mmHg |
2.47 |
6.99 |
radiotelemetry |
|
0.0 |
0 |
|
|
97968 |
1958 |
SHRSP/Gcrc |
pulse pressure |
controlled sodium content drinking water (1 %) (between 9 and 12 days) |
Clark JS, et al., Hypertension 1996 Nov;28(5):898-906 |
arterial blood pressure trait |
female |
137 days-140 days |
6 |
continuous mean |
63.8 |
mmHg |
1.63 |
4.0 |
intra-aortic abdominal radiotelemetry |
abdominal aorta |
|
0 |
|
|
11638 |
109 |
SS.SR-(D2Rat352-rs63922710)/Opaz |
pulse pressure |
controlled sodium content diet (8 %) (between 24 and 28 days) |
Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. |
arterial blood pressure trait |
male |
108 days-112 days |
6 |
|
51.8 |
mmHg |
2.3 |
5.63 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
0 |
|
|
70565 |
1458 |
SS-Nppbem2Mcwi-/- |
pulse pressure |
control condition (for 84 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
84 days
| 2 |
|
392.0 |
mmHg |
9.0 |
12.73 |
intra-aortic abdominal radiotelemetry via abdominal aorta cannulation |
|
0.0 |
0 |
|
|
99538 |
2319 |
SS-Nppbem2Mcwi-/- |
pulse pressure |
control condition (for 168 days) |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
168 days
| 3 |
|
42.0 |
mmHg |
5.0 |
8.66 |
intra-aortic abdominal radiotelemetry via abdominal aorta cannulation |
|
0.0 |
0 |
|
|
99540 |
2319 |
SS.SHR-(D9Mco113-D9Mco124)/Bj |
pulse pressure |
controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) |
Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. |
arterial blood pressure trait |
male |
68 days-70 days |
6 |
serial mean |
38.3 |
mmHg |
4.21 |
10.31 |
radiotelemetry |
|
0.0 |
0 |
|
|
97969 |
1958 |