Study ID,Study,Experiment Name,Experiment Notes,Strain Ont ID,Strain,Sex,Age,# of Animals,Sample Notes,Clinical Measurement Ont ID,Phenotype,Formula,Clinical Measurement Notes,Average Type,Value,Units,SEM,SD,Method Ont ID,Method,Method Site,Method Duration,Method Notes,Post Insult Type,Post Insult Time Value,Post Insult Time Unit,Conditions,Record ID, 1498,NBRP Hematology & Blood Biochemistry data,blood albumin amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000056,plasma albumin level,,,,0.42,g/l,0.0082,0.02,MMO:0000351,automated plasma albumin analysis,,,"Hitachi, model 7170 ",,,,fasting (for 16 hours),78380,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood triglyceride amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000548,plasma triglyceride level,,,,0.6667,mmol/l,0.0738,0.1808,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78386,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood hemoglobin amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000026,blood hemoglobin level,,,,16.6,g/dl,0.2041,0.5,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78367,fasting (for 16 hours) 41,NBRP Organ Weight data,lung mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000097,lung wet weight,,,,0.978,g,0.0302,0.074,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72229,specific pathogen-free condition 41,NBRP Organ Weight data,spleen mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000149,spleen weight to body weight ratio,,,,0.215,%,0.0061,0.015,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72238,specific pathogen-free condition 1498,NBRP Hematology & Blood Biochemistry data,erythrocyte size trait,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000038,mean corpuscular volume,,,,61.5,fl,0.7348,1.8,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78369,fasting (for 16 hours) 22,NBRP Body Temperature data,body temperature trait,,RS:0000482,GK/Slc,male,70 days to 56 days,6,,CMO:0000015,body temperature,,,serial mean,37.9,degrees C,0.1225,0.3,MMO:0000034,digital rectal thermometry,,,,,,,specific pathogen-free condition,75065,specific pathogen-free condition 41,NBRP Organ Weight data,kidney mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000140,both kidneys wet weight as percentage of body weight,,,,0.752,%,0.0314,0.077,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72234,specific pathogen-free condition 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood LDL cholesterol amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000053,blood low density lipoprotein cholesterol level,,n=4-6,,29,mg/dl,2.1,,MMO:0000279,blood low-density lipoprotein-cholesterol measurement test,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102901,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood LDL cholesterol amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000053,blood low density lipoprotein cholesterol level,,n=4-6,,24.3,mg/dl,1.8,,MMO:0000279,blood low-density lipoprotein-cholesterol measurement test,,0.0,,,,,vehicle control condition,102900,vehicle control condition 1498,NBRP Hematology & Blood Biochemistry data,erythrocyte quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000037,hematocrit,,,,55,%,0.694,1.7,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78368,fasting (for 16 hours) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood cholesterol amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000051,blood total cholesterol level,,n=4-6,,78.8,mg/dl,3.8,,MMO:0000491,blood cholesterol analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102893,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood cholesterol amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000051,blood total cholesterol level,,n=4-6,,77.8,mg/dl,5.2,,MMO:0000491,blood cholesterol analysis,,0.0,,,,,vehicle control condition,102892,vehicle control condition 41,NBRP Organ Weight data,brain mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000139,brain weight to body weight ratio,,,,0.673,%,0.0151,0.037,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72226,specific pathogen-free condition 41,NBRP Organ Weight data,liver mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000141,liver weight as percentage of body weight,,,,3.131,%,0.1286,0.315,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72232,specific pathogen-free condition 14,NBRP Blood Pressure and Heart Rate data,arterial blood pressure trait,,RS:0000482,GK/Slc,male,70 days to 56 days,6,,CMO:0000004,systolic blood pressure,,,serial mean,130,mmHg,4.4907,11.0,MMO:0000052,tail cuff photoplethysmography,,,"NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan",,,,specific pathogen-free condition,75063,specific pathogen-free condition 41,NBRP Organ Weight data,lung mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000156,lung weight to body weight ratio,,,,0.352,%,0.0094,0.023,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72230,specific pathogen-free condition 41,NBRP Organ Weight data,liver mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000158,liver wet weight,,,,8.699,g,0.2715,0.665,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72231,specific pathogen-free condition 1498,NBRP Hematology & Blood Biochemistry data,blood creatinine amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000537,plasma creatinine level,,,,0.2,mg/dl,0.0082,0.02,MMO:0000354,automated plasma creatinine analysis,,,"Hitachi, model 7170 ",,,,fasting (for 16 hours),78389,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood cholesterol amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000585,plasma total cholesterol level,,,,99,mg/dl,2.0412,5.0,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78383,fasting (for 16 hours) 41,NBRP Organ Weight data,adrenal gland mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000164,both adrenal glands wet weight,,,,36.3,mg,2.5311,6.2,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72235,specific pathogen-free condition 1498,NBRP Hematology & Blood Biochemistry data,blood glucose amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000042,plasma glucose level,,,,250,mg/dl,8.165,20.0,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78382,fasting (for 16 hours) 14,NBRP Blood Pressure and Heart Rate data,heart pumping trait,,RS:0000482,GK/Slc,male,70 days to 56 days,6,,CMO:0000002,heart rate,,,serial mean,446,beats/min,15.5134,38.0,MMO:0000052,tail cuff photoplethysmography,,,"NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan",,,,specific pathogen-free condition,75064,specific pathogen-free condition 41,NBRP Organ Weight data,brain mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000155,brain wet weight,,,,1.871,g,0.0184,0.045,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72225,specific pathogen-free condition 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood HDL cholesterol amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000052,blood high density lipoprotein cholesterol level,,n=4-6,,7,mg/dl,0.7,,MMO:0000278,blood high-density lipoprotein-cholesterol measurement test,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102897,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood HDL cholesterol amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000052,blood high density lipoprotein cholesterol level,,n=4-6,,9,mg/dl,0.9,,MMO:0000278,blood high-density lipoprotein-cholesterol measurement test,,0.0,,,,,vehicle control condition,102896,vehicle control condition 1498,NBRP Hematology & Blood Biochemistry data,blood hemoglobin amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000291,mean corpuscular hemoglobin concentration,,,,30.2,g/dl,0.1633,0.4,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78371,fasting (for 16 hours) 41,NBRP Organ Weight data,heart mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000069,heart wet weight,,,,0.966,g,0.0192,0.047,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72227,specific pathogen-free condition 41,NBRP Organ Weight data,kidney mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000085,both kidneys wet weight,,,,2.089,g,0.0612,0.15,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72233,specific pathogen-free condition 1498,NBRP Hematology & Blood Biochemistry data,blood hemoglobin amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000290,mean corpuscular hemoglobin level,,,,18.6,pg,0.1225,0.3,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78370,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood HDL cholesterol amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000646,plasma high density lipoprotein cholesterol level,,,,66.8,mg/dl,0.4491,1.1,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78384,fasting (for 16 hours) 41,NBRP Organ Weight data,testis mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000175,both testes wet weight,,,,2.551,g,0.0416,0.102,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72239,specific pathogen-free condition 1498,NBRP Hematology & Blood Biochemistry data,blood LDL cholesterol amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000647,plasma low density lipoprotein cholesterol level,,,,11,mg/dl,0.8165,2.0,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78385,fasting (for 16 hours) 41,NBRP Organ Weight data,testis mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000901,both testes wet weight to body weight ratio,,,,0.918,%,0.0249,0.061,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72240,specific pathogen-free condition 41,NBRP Organ Weight data,spleen mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000171,spleen wet weight,,,,0.599,g,0.0171,0.042,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72237,specific pathogen-free condition 41,NBRP Organ Weight data,adrenal gland mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000621,both adrenal glands weight to body weight ratio,,,,13.1,mg/100g,0.8981,2.2,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72236,specific pathogen-free condition 21,NBRP Body Weight data,body mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000012,body weight,,,,245,g,3.8784,9.5,MMO:0000017,whole body digital scale,,,,,,,specific pathogen-free condition,70810,specific pathogen-free condition 21,NBRP Body Weight data,body mass,,RS:0000482,GK/Slc,male,42 days,6,,CMO:0000012,body weight,,,,171.7,g,1.9596,4.8,MMO:0000017,whole body digital scale,,,,,,,specific pathogen-free condition,70811,specific pathogen-free condition 21,NBRP Body Weight data,body mass,,RS:0000482,GK/Slc,male,35 days,6,,CMO:0000012,body weight,,,,112.9,g,0.939,2.3,MMO:0000017,whole body digital scale,,,,,,,specific pathogen-free condition,70809,specific pathogen-free condition 1498,NBRP Hematology & Blood Biochemistry data,blood urea nitrogen amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000586,plasma urea nitrogen level,,,,4.8909,mmol/l,0.3935,0.9639,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78388,fasting (for 16 hours) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine output,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000260,timed urine volume,,n=4-6,,29.3,ml/d,3.6,,MMO:0000147,urine analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102925,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine output,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000260,timed urine volume,,n=4-6,,9.6,ml/d,0.7,,MMO:0000147,urine analysis,,0.0,,,,,vehicle control condition,102924,vehicle control condition 1498,NBRP Hematology & Blood Biochemistry data,blood total protein amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000054,plasma total protein level,,,,64,mg/ml,0.4082,1.0,MMO:0000356,automated plasma total protein analysis,,,"Hitachi, model 7170 ",,,,fasting (for 16 hours),78379,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,basophil quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000368,blood basophil count to total leukocyte count ratio,,,,0,%,0.0,0.0,MMO:0000145,automated differential white blood cell count test,,,May-Giemsa staining,,,,fasting (for 16 hours),78395,fasting (for 16 hours) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood urea nitrogen amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000049,blood urea nitrogen level,,n=4-6,,16.1,mg/dl,1.0,,MMO:0000253,blood urea nitrogen analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102905,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood urea nitrogen amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000049,blood urea nitrogen level,,n=4-6,,15.7,mg/dl,1.2,,MMO:0000253,blood urea nitrogen analysis,,0.0,,,,,vehicle control condition,102904,vehicle control condition 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood creatinine amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000538,blood creatinine level,,n=4-6,,0.24,mg/dl,0.0,,MMO:0000270,blood creatinine analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102909,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood creatinine amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000538,blood creatinine level,,n=4-6,,0.26,mg/dl,0.02,,MMO:0000270,blood creatinine analysis,,0.0,,,,,vehicle control condition,102908,vehicle control condition 1498,NBRP Hematology & Blood Biochemistry data,blood phosphate amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000058,plasma phosphate level,,,,6.5,mg/dl,0.2041,0.5,MMO:0000037,automated blood electrolyte analysis,,,"Hitachi, model 7170 ",,,,fasting (for 16 hours),78390,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood coagulation trait,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000210,activated partial thromboplastin time,,,,14.5,s,0.5715,1.4,MMO:0000178,automated coagulometer method,,,"Sysmex, CA-3000 type",,,,fasting (for 16 hours),78375,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood coagulation trait,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000211,prothrombin time,,,,13.7,s,0.1633,0.4,MMO:0000178,automated coagulometer method,,,"Sysmex, CA-3000 type",,,,fasting (for 16 hours),78374,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,eosinophil quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000369,blood eosinophil count to total leukocyte count ratio,,,,1,%,0.4082,1.0,MMO:0000145,automated differential white blood cell count test,,,May-Giemsa staining,,,,fasting (for 16 hours),78396,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,effector T cell quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000371,blood lymphocyte count to total leukocyte count ratio,,,,87,%,1.2247,3.0,MMO:0000145,automated differential white blood cell count test,,,May-Giemsa staining,,,,fasting (for 16 hours),78399,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,monocyte quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000374,blood monocyte count to total leukocyte count ratio,,,,0,%,0.0,0.0,MMO:0000145,automated differential white blood cell count test,,,May-Giemsa staining,,,,fasting (for 16 hours),78400,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood calcium amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000378,total plasma calcium level,,,,10,mg/dl,0.0816,0.2,MMO:0000037,automated blood electrolyte analysis,,,"Hitachi, model 7170 ",,,,fasting (for 16 hours),78391,fasting (for 16 hours) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood triglyceride amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000118,blood triglyceride level,,n=4-6,,31,mg/dl,3.9,,MMO:0000233,blood triglyceride analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102889,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood triglyceride amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000118,blood triglyceride level,,n=4-6,,52.3,mg/dl,7.4,,MMO:0000233,blood triglyceride analysis,,0.0,,,,,vehicle control condition,102888,vehicle control condition 1498,NBRP Hematology & Blood Biochemistry data,blood alkaline phosphatase amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000045,plasma alkaline phosphatase activity level,,,,453,IU/l,9.3897,23.0,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78378,fasting (for 16 hours) 1662,NBRP Urine Volume and Urine Electrolyte data,urine chloride amount,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0000382,urine chloride level,,,,142,mEq/L,6.9402,17.0,MMO:0000177,automated urine analysis,,,,,,,0.9% sodium chloride solution (25 ml/kg) ,95210,0.9% sodium chloride solution (25 ml/kg) 1662,NBRP Urine Volume and Urine Electrolyte data,urine potassium amount,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0002159,urine potassium excretion rate to body weight ratio,,,,182,uEq/100g/6 hrs,5.7155,14.0,MMO:0000177,automated urine analysis,,,"Analytical intruments, PVA alpha II",,,,0.9% sodium chloride solution (25 ml/kg) ,95209,0.9% sodium chloride solution (25 ml/kg) 1662,NBRP Urine Volume and Urine Electrolyte data,urine chloride amount,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0002158,urine chloride excretion rate to body weight ratio,,,,377,uEq/100g/6 hrs,15.9217,39.0,MMO:0000177,automated urine analysis,,,,,,,0.9% sodium chloride solution (25 ml/kg) ,95211,0.9% sodium chloride solution (25 ml/kg) 1498,NBRP Hematology & Blood Biochemistry data,erythrocyte quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000025,red blood cell count,,,,0.895,x 10E6 cells/ul,0.0155,0.038,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78366,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,leukocyte quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000027,white blood cell count,,,,6.1,x 1000 cells/ul,0.3266,0.8,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78372,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,platelet quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000029,platelet count,,,,709,x 1000 cells/ul,27.3526,67.0,MMO:0000225,automated cell/particle size/count analysis method,,,"Sysmex, F-800 type",,,,fasting (for 16 hours),78373,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood bilirubin amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0002334,total plasma bilirubin level,,total plasma bilirubin level,,0.08,mg/dl,0.0041,0.01,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78387,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood sodium amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000060,plasma sodium level,,,,144.7,mmol/l,0.6124,1.5,MMO:0000037,automated blood electrolyte analysis,,,"Analytical intruments, PVA alpha II",,,,fasting (for 16 hours),78392,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood potassium amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000061,plasma potassium level,,,,4.11,mmol/l,0.3062,0.75,MMO:0000037,automated blood electrolyte analysis,,,"Analytical intruments, PVA alpha II",,,,fasting (for 16 hours),78393,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood chloride amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000059,plasma chloride level,,,,105,mmol/l,0.4082,1.0,MMO:0000037,automated blood electrolyte analysis,,,"Analytical intruments, PVA alpha II",,,,fasting (for 16 hours),78394,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood aspartate transaminase amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000043,plasma aspartate aminotransferase activity level,,,,65,U/l,5.7155,14.0,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78376,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood alanine transaminase amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000044,plasma alanine aminotransferase activity level,,,,44,U/l,7.3485,18.0,MMO:0000553,automated plasma analysis,,,PMID:15591307,,,,fasting (for 16 hours),78377,fasting (for 16 hours) 1662,NBRP Urine Volume and Urine Electrolyte data,urine potassium amount,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0000128,urine potassium level,,,,68.6,mmol/l,3.8375,9.4,MMO:0000177,automated urine analysis,,,"Analytical intruments, PVA alpha II",,,,0.9% sodium chloride solution (25 ml/kg) ,95208,0.9% sodium chloride solution (25 ml/kg) 1662,NBRP Urine Volume and Urine Electrolyte data,urine sodium amount,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0000129,urine sodium level,,,,139.1,mmol/l,4.654,11.4,MMO:0000177,automated urine analysis,,,"Analytical intruments, PVA alpha II",,,,0.9% sodium chloride solution (25 ml/kg) ,95206,0.9% sodium chloride solution (25 ml/kg) 1662,NBRP Urine Volume and Urine Electrolyte data,urine output,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0000260,timed urine volume,,,,30.68,ml/d,2.1556,5.28,MMO:0000511,metabolic cage urine volume measurement method,,,,,,,0.9% sodium chloride solution (25 ml/kg) ,95204,0.9% sodium chloride solution (25 ml/kg) 1662,NBRP Urine Volume and Urine Electrolyte data,urine sodium amount,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0001855,urine sodium excretion rate to body weight ratio,,,,0.010416,uEq/min/g,5.0E-4,0.0013,MMO:0000177,automated urine analysis,,,"Analytical intruments, PVA alpha II",,,,0.9% sodium chloride solution (25 ml/kg) ,95207,0.9% sodium chloride solution (25 ml/kg) 1662,NBRP Urine Volume and Urine Electrolyte data,urine output,,RS:0000482,GK/Slc,male,63 days,6,,CMO:0001968,timed urine volume to body weight ratio,,,,0.0756,ul/min/g,0.0057,0.014,MMO:0000511,metabolic cage urine volume measurement method,,,,,,,0.9% sodium chloride solution (25 ml/kg) ,95205,0.9% sodium chloride solution (25 ml/kg) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood hemoglobin amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002786,blood hemoglobin A1c level,,HbA1c n=4-6,,5.465,%,0.03,,MMO:0000169,standard blood chemistry panel,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102881,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood hemoglobin amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002786,blood hemoglobin A1c level,,HbA1c n=4-6,,5.21,%,0.12,,MMO:0000169,standard blood chemistry panel,,0.0,,,,,vehicle control condition,102880,vehicle control condition 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine glucose amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000383,urine glucose level,,n=4-6,,9401,mg/dl,1647.7,,MMO:0000147,urine analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102929,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine glucose amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0000383,urine glucose level,,n=4-6,,588.3,mg/dl,349.4,,MMO:0000147,urine analysis,,0.0,,,,,vehicle control condition,102928,vehicle control condition 1498,NBRP Hematology & Blood Biochemistry data,neutrophil quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0002337,blood segmented neutrophil count to total leukocyte count ratio,,segmented neutrophil %,,12,%,1.2247,3.0,MMO:0000145,automated differential white blood cell count test,,,May-Giemsa staining,,,,fasting (for 16 hours),78398,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,blood albumin amount,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0002342,plasma albumin to plasma total protein ratio,,plasma albumin to plasma total protein ratio,,1.82,,0.0612,0.15,MMO:0000352,automated plasma protein analysis,,,"Hitachi, model 7170 ",,,,fasting (for 16 hours),78381,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,leukocyte quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0002339,non-specified leukocyte count to total leukocyte count ratio,,unidentified differential wbc,,0,%,0.0,0.0,MMO:0000145,automated differential white blood cell count test,,,May-Giemsa staining,,,,fasting (for 16 hours),78401,fasting (for 16 hours) 1498,NBRP Hematology & Blood Biochemistry data,neutrophil quantity,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0002338,blood band neutrophil count to total leukocyte count ratio,,band neutrophil %,,0,%,0.0,0.0,MMO:0000145,automated differential white blood cell count test,,,May-Giemsa staining,,,,fasting (for 16 hours),78397,fasting (for 16 hours) 41,NBRP Organ Weight data,heart mass,,RS:0000482,GK/Slc,male,70 days,6,,CMO:0000074,heart weight to body weight ratio,,,,3.48,g/kg,0.1021,0.25,MMO:0000006,Shimadzu electronic balance post excision weight measurement,,,,,,,specific pathogen-free condition,72228,specific pathogen-free condition 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine ketone body amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002897,urine acetoacetone level,,n=4-6,,321.5,umol/l,74.8,,MMO:0000147,urine analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102917,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine ketone body amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002897,urine acetoacetone level,,n=4-6,,91.5,umol/l,39.9,,MMO:0000147,urine analysis,,0.0,,,,,vehicle control condition,102916,vehicle control condition 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood albumin amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002898,blood glycated albumin level,,glycated albumin n=4-6,,1.9,%,0.09,,MMO:0000169,standard blood chemistry panel,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102877,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",blood albumin amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002898,blood glycated albumin level,,glycated albumin n=4-6,,2.3,%,0.07,,MMO:0000169,standard blood chemistry panel,,0.0,,,,,vehicle control condition,102876,vehicle control condition 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine ketone body amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002896,urine 3-hydroxybutyrate level,,n=4-6,,1161.8,umol/l,301.9,,MMO:0000147,urine analysis,,0.0,,,,,controlled ipragliflozin content diet (0.008 %) (for 21 days),102921,controlled ipragliflozin content diet (0.008 %) (for 21 days) 2781,"Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.",urine ketone body amount,,RS:0000482,GK/Slc,male,105 days,N/A,,CMO:0002896,urine 3-hydroxybutyrate level,,n=4-6,,323.3,umol/l,92.7,,MMO:0000147,urine analysis,,0.0,,,,,vehicle control condition,102920,vehicle control condition