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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1aCondition 1bCondition 1cCondition 2aCondition 2bCondition 3
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87arterial blood pressure traitRS:0000817SS/Jrmale57 days to 56 days6CMO:0000004systolic blood pressureserial mean168mmHg5.112.4924MMO:0000031tail cuff plethysmographytailbetween 7 am and 12 pmnaive control condition11584naive control condition
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87arterial blood pressure traitRS:0000817SS/Jrmale183 days to 182 days6CMO:0000004systolic blood pressureserial mean208mmHg4.611.2677MMO:0000031tail cuff plethysmographytail2 days between 7 am and 12 pmnaive control condition11596naive control condition
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23heart mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days46CMO:0000069heart wet weight1.233g0.01090.0739MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 24 and 27 days)64743controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23heart mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days20CMO:0000069heart wet weight1.206g0.01550.0693MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 24 and 27 days)64762controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23heart mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days19CMO:0000069heart wet weight1.211g0.01710.0745MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 24 and 27 days)64764controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23heart mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days40CMO:0000073calculated heart weightregression of heart weight on body weight1.178g0.00930.0588MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 24 and 27 days)64766controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23heart mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days19CMO:0000073calculated heart weightregression of heart weight on body weight1.197g0.01410.0615MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 24 and 27 days)64768controlled sodium content diet (2 %) (between 24 and 27 days)
226Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161heart right ventricle massRS:0000817SS/Jrmale98 days16CMO:0000914heart right ventricle weight to body weight ratio0.69mg/g0.020.08MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 35 and 98 days)64893controlled sodium content diet (2 %) (between 35 and 98 days)
226Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161heart left ventricle massRS:0000817SS/Jrmale98 days16CMO:0000530heart left ventricle weight to body weight ratio3.41mg/g0.090.36MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 35 and 98 days)64892controlled sodium content diet (2 %) (between 35 and 98 days)
145Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6.arterial blood pressure traitRS:0000817SS/Jrmale65 days to 61 days20CMO:0000004systolic blood pressureaverage of 12 readings from 4 sessions serial mean202.7mmHg3.716.5469MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (between 24 and 28 days)11775controlled sodium content diet (0.2 %) (for 7 days)controlled sodium content diet (2 %) (between 24 and 28 days)
145Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6.heart massRS:0000817SS/Jrmale65 days20CMO:0000069heart wet weight1.289g0.0170.076MMO:0000005post excision weight measurementcontrolled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 28 days)11777controlled sodium content diet (0.2 %) (for 7 days)controlled sodium content diet (2 %) (for 28 days)
146Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.arterial blood pressure traitRS:0000817SS/Jrmale100 days21CMO:0000004systolic blood pressureserial mean244mmHg6.228.412MMO:0000031tail cuff plethysmographycontrolled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days)11781controlled sodium content diet (1 %) (for 30 days)controlled sodium content diet (0.2 %) (for 40 days)
146Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.arterial blood pressure traitRS:0000817SS/Jrmale61 days20CMO:0000004systolic blood pressureserial mean199.3mmHg7.533.541MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 24 days)11787controlled sodium content diet (0.2 %) (for 7 days)controlled sodium content diet (2 %) (for 24 days)
146Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.arterial blood pressure traitRS:0000817SS/Jrmale79 days20CMO:0000004systolic blood pressureserial mean231.4mmHg7.232.1994MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 42 days)11789controlled sodium content diet (0.2 %) (for 7 days)controlled sodium content diet (2 %) (for 42 days)
146Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.arterial blood pressure traitRS:0000817SS/Jrmale61 days22CMO:0000004systolic blood pressureserial mean264mmHg5.525.7973MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days)11791controlled sodium content diet (0.2 %) (for 7 days)controlled sodium content diet (4 %) (for 24 days)
146Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.arterial blood pressure traitRS:0000817SS/Jrfemale61 days24CMO:0000004systolic blood pressureserial mean250.1mmHg4.924.005MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days)11792controlled sodium content diet (0.2 %) (for 7 days)controlled sodium content diet (4 %) (for 24 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days20CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean224.9mmHg4.821.4663MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11795controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days20CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean243.4mmHg4.017.8885MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11801controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days20CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean230.6mmHg4.721.019MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11807controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days20CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean235.1mmHg4.620.5718MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11813controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days20CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean232.7mmHg3.214.3108MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11819controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days19CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean221.8mmHg2.912.6408MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11825controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
148Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.arterial blood pressure traitRS:0000817SS/Jrnot specified68 days to 64 days18CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean217mmHg4.016.9706MMO:0000031tail cuff plethysmographycontrolled sodium content diet (2 %) (between 25 and 28 days)11831controlled sodium content diet (2 %) (between 25 and 28 days)
148Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.arterial blood pressure traitRS:0000817SS/Jrnot specified68 days to 64 days20CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean205mmHg2.912.9692MMO:0000031tail cuff plethysmographycontrolled sodium content diet (2 %) (between 25 and 28 days)11837controlled sodium content diet (2 %) (between 25 and 28 days)
148Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.arterial blood pressure traitRS:0000817SS/Jrnot specified68 days to 64 days41CMO:0000004systolic blood pressureaverage of 12 readings from 4 daily sessions serial mean205mmHg2.616.6481MMO:0000031tail cuff plethysmographycontrolled sodium content diet (2 %) (between 25 and 28 days)11841controlled sodium content diet (2 %) (between 25 and 28 days)
150Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5.arterial blood pressure traitRS:0000817SS/Jrmale76 days to 70 days24CMO:0000004systolic blood pressureserial mean217mmHg3.416.6565MMO:0000031tail cuff plethysmographycontrolled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days)11845controlled sodium content diet (0.2 %) (between 15 and 18 days)controlled sodium content diet (2 %) (between 25 and 28 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.221g0.01710.0765MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11797controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight298.2g4.218.783MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11799controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
146Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.heart massRS:0000817SS/Jrmale100 days21CMO:0000069heart wet weight1.284g0.0240.11MMO:0000005post excision weight measurementcontrolled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days)11783controlled sodium content diet (1 %) (for 30 days)controlled sodium content diet (0.2 %) (for 40 days)
146Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902.body massRS:0000817SS/Jrmale100 days21CMO:0000012body weight350g7.333.4528MMO:0000016body weighing methodcontrolled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days)11785controlled sodium content diet (1 %) (for 30 days)controlled sodium content diet (0.2 %) (for 40 days)
148Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.heart massRS:0000817SS/Jrnot specified68 days to 64 days41CMO:0000074heart weight to body weight ratio4.06g/kg0.040.2561MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 25 and 28 days)11843controlled sodium content diet (2 %) (between 25 and 28 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.heart massRS:0000817SS/Jrmale70 days to 68 days19CMO:0000069heart wet weight1.289g0.0180.0785MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11827controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.body massRS:0000817SS/Jrmale70 days to 68 days19CMO:0000012body weight302.3g3.515.2561MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11829controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87arterial blood pressure traitRS:0000817SS/Jrmale141 days to 140 days6CMO:0000004systolic blood pressureserial mean193mmHg10.525.7196MMO:0000031tail cuff plethysmographytail2 days between 7 am and 12 pmnaive control condition11592naive control condition
148Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.heart massRS:0000817SS/Jrnot specified68 days to 64 days20CMO:0000074heart weight to body weight ratio3.95g/kg0.050.2236MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 25 and 28 days)11839controlled sodium content diet (2 %) (between 25 and 28 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.243g0.01480.0662MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11821controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight297.7g2.511.1803MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11823controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87arterial blood pressure traitRS:0000817SS/Jrmale85 days to 84 days6CMO:0000004systolic blood pressureserial mean182mmHg4.110.0429MMO:0000031tail cuff plethysmographytail2 days between 7 am and 12 pmnaive control condition11588naive control condition
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.271g0.02840.127MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11815controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight289.8g3.214.3108MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11817controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
148Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35.heart massRS:0000817SS/Jrnot specified68 days to 64 days18CMO:0000074heart weight to body weight ratio4.3g/kg0.060.2546MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 25 and 28 days)11834controlled sodium content diet (2 %) (between 25 and 28 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.253g0.02050.0917MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11809controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight297.1g2.310.2859MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11811controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.279g0.01610.072MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11803controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
147Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight289.4g2.08.9443MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days)11805controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 27 days)
145Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6.body massRS:0000817SS/Jrmale65 days20CMO:0000012body weight306.8g4.620.5718MMO:0000016body weighing method0controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 28 days)11779controlled sodium content diet (0.2 %) (for 7 days)controlled sodium content diet (2 %) (for 28 days)
205Saad Y, et al., Hypertension. 2007arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days0CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days197mmHg3.74MMO:0000031tail cuff plethysmographywarm up to 28 Ccontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11907controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days0CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days204mmHg3.72MMO:0000031tail cuff plethysmographywarm up to 28 Ccontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11911controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days0CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days198mmHg3.62MMO:0000031tail cuff plethysmographywarm up to 28 Ccontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11912controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days0CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days221mmHg3.95MMO:0000031tail cuff plethysmographywarm up to 28 Ccontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11913controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.161g/kg0.0460.2057MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11914controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.265g/kg0.0320.1431MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11931controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.048g/kg0.0340.1521MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11932controlled sodium content diet (2 %) (between 24 and 27 days)
226Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161arterial blood pressure traitRS:0000817SS/Jrmale98 days to 68 days16CMO:0000009mean arterial blood pressure177mmHg5.020.0MMO:0000015radiotelemetry30controlled sodium content diet (2 %) (between 35 and 98 days)11970controlled sodium content diet (2 %) (between 35 and 98 days)
205Saad Y, et al., Hypertension. 2007body massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000012body weight331g2.08MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11975controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007body massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000012body weight337g2.36MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11973controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007body massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000012body weight302g5.58MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11974controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007body massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000012body weight310g2.38MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11976controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000069heart wet weight1.31g0.01MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)11982controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.386g/kg0.0540.2415MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11987controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.346g/kg0.0660.2952MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11988controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.26g/kg0.0670.2996MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11989controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.308g/kg0.0610.2728MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11990controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.105g/kg0.0430.1923MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11992controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.221g/kg0.0640.2862MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11993controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.086g/kg0.0310.1386MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11994controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.239g/kg0.0870.3891MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11995controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.162g/kg0.0370.1655MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11996controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.084g/kg0.0380.1699MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11998controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.297g/kg0.0940.4204MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)11999controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.418g/kg0.0610.2728MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)12001controlled sodium content diet (2 %) (between 24 and 27 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.241g/kg0.0330.1476MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)12003controlled sodium content diet (2 %) (between 24 and 27 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000069heart wet weight1.26g0.01MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12007controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000069heart wet weight1.36g0.01MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12010controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000069heart wet weight1.32g0.01MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12011controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000074heart weight to body weight ratio3.9g/kg0.04MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12039controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000074heart weight to body weight ratio4.2g/kg0.07MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12043controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000074heart weight to body weight ratio4.12g/kg0.04MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12045controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007heart massRS:0000817SS/Jrmale66 days to 64 days0CMO:0000074heart weight to body weight ratio4.27g/kg0.05MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12048controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
205Saad Y, et al., Hypertension. 2007arterial blood pressure traitRS:0000817SS/Jrmale84 days to 81 days9CMO:0000004systolic blood pressurerecorded every 5 minutes for 4 days213mmHg7.4722.41MMO:0000070intra-aortic abdominal radiotelemetryaorta345600.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 42 days)12072controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 42 days)
226Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161body massRS:0000817SS/Jrmale98 days16CMO:0000012body weight348g9.036.0MMO:0000016body weighing method0controlled sodium content diet (2 %) (between 35 and 98 days)12079controlled sodium content diet (2 %) (between 35 and 98 days)
231Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202heart massRS:0000817SS/Jrmale68 days24CMO:0000074heart weight to body weight ratio3.8g/kg0.0470.2303MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12084controlled sodium content diet (2 %) (for 28 days)
231Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202heart massRS:0000817SS/Jrmale68 days21CMO:0000074heart weight to body weight ratio4.23g/kg0.0540.2475MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12085controlled sodium content diet (2 %) (for 28 days)
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87heart massRS:0000817SS/Jrmale183 days6CMO:0000073calculated heart weightadjusted heart weight for differences in body weight by regression analysis using programs from SPSS1.675g0.0180.0441MMO:0000005post excision weight measurement0naive control condition65448naive control condition
589Ariyarajah A, et al., J Hypertens 2004 Aug;22(8):1495-502.arterial blood pressure traitRS:0000817SS/Jrmale74 days to 66 days16CMO:0000009mean arterial blood pressure172mmHg4.016.0MMO:0000015radiotelemetry0controlled sodium content diet (2 %) (between 31 and 38 days)65472controlled sodium content diet (2 %) (between 31 and 38 days)
610Moujahidine M, et al., Hypertens Res 2004 Mar;27(3):203-12.arterial blood pressure traitRS:0000817SS/Jrmale98 days16CMO:0000009mean arterial blood pressureaverage of 6hrserial mean171mmHg4.016.0MMO:0000015radiotelemetry120controlled sodium content diet (2 %) (for 63 days)65475controlled sodium content diet (2 %) (for 63 days)
272Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5.arterial blood pressure traitRS:0000817SS/Jrmale66 days to 63 days8CMO:0000009mean arterial blood pressure5 hr recording session - 1 min. averagesserial mean122mmHgMMO:0000015radiotelemetryfemoral arteryconnected to solid-state transducer (Argon Medical Technologies, Athens, TX)naive control condition12622naive control condition
272Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5.arterial blood pressure traitRS:0000817SS/Jrmale80 days8CMO:0000009mean arterial blood pressure5 hr recording session - 1 min. averages, averaged over 4 daysserial mean185mmHgMMO:0000015radiotelemetryfemoral arteryconnected to solid-state transducer (Argon Medical Technologies, Athens, TX)controlled sodium content diet (8 %) (for 14 days)12649controlled sodium content diet (8 %) (for 14 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.23g0.0180.0805MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12663controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale60 days to 42 days15CMO:0000004systolic blood pressure173.5mmHg4.015.4919MMO:0000052tail cuff photoplethysmography172800controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 17 and 18 days)12664controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 17 and 18 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale69 days to 42 days15CMO:0000004systolic blood pressure181.9mmHg4.115.8792MMO:0000052tail cuff photoplethysmography172800controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 26 and 27 days)12665controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 26 and 27 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.31g0.0150.0671MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12667controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.26g0.030.1342MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12669controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.25g0.010.0447MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12671controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.21g0.0070.0313MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12673controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.18g0.0130.0581MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12674controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.26g0.0470.2102MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12675controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days30CMO:0000069heart wet weight1.25g0.0130.0712MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12677controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight303g2.8612.7903MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12688controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight311g2.119.4362MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (for 30 days) then controlled sodium content diet (2 %) (for 28 days)12689controlled sodium content diet (0.3 %) (for 30 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight297g3.7516.7705MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12690controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight320g1.526.7976MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12691controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days44CMO:0000012body weight314g2.013.2665MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12692controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight307g3.2314.445MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12693controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight318g2.2510.0623MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12694controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.body massRS:0000817SS/Jrmale70 days to 68 days30CMO:0000012body weight303g1.9210.5163MMO:0000017whole body digital scale0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12695controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
221Garrett MR, et al., Hypertension 2001 Oct;38(4):779-85heart massRS:0000817SS/Jrmale69 days to 64 days20CMO:0000074heart weight to body weight ratio4.266g/kg0.0540.2415MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (between 24 and 27 days)12700controlled sodium content diet (2 %) (between 24 and 27 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.26g/kg0.0670.2996MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12707controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio3.96g/kg0.0530.237MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12708controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.26g/kg0.1630.729MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12709controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio3.9g/kg0.0240.1073MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12710controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days44CMO:0000074heart weight to body weight ratio3.88g/kg0.0290.1924MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12711controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio3.85g/kg0.0480.2147MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12712controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days30CMO:0000074heart weight to body weight ratio3.95g/kg0.0480.2629MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12713controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.heart massRS:0000817SS/Jrmale70 days to 68 days30CMO:0000074heart weight to body weight ratio4.15g/kg0.050.2739MMO:0000157digital scale post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12714controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
304Chauvet C, et al., J Hypertens. 2008 May;26(5):893-901.arterial blood pressure traitRS:0000817SS/Jrmale78 days to 66 days21CMO:0000009mean arterial blood pressureaverage of 24 hour averages over 12 daysserial mean177mmHg6.027.4955MMO:0000070intra-aortic abdominal radiotelemetryabdominal aorta1036800.0telemetry probe model PA-D70, Data Sciences, St. Paul, MNcontrolled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 50 days)12737controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (between 31 and 50 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days20CMO:0000004systolic blood pressureaverage of 2-3 readings/day over 4 days195mmHg3.2714.6239MMO:0000031tail cuff plethysmography4semi- automatic equipment from IITC, Woodland Hills, CAcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12807controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days20CMO:0000004systolic blood pressureaverage of 2-3 readings/day over 4 days194mmHg3.3815.1158MMO:0000031tail cuff plethysmography4semi- automatic equipment from IITC, Woodland Hills, CAcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12808controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000074heart weight to body weight ratio4.29g/kg0.10.4472MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12216controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000074heart weight to body weight ratio4.28g/kg0.030.1342MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12217controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000074heart weight to body weight ratio3.83g/kg0.040.1789MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12218controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000074heart weight to body weight ratio4.08g/kg0.050.2236MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12219controlled sodium content diet (2 %) (for 24 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.heart massRS:0000817SS/Jrmale72 days to 70 days40CMO:0000069heart wet weight1.134g0.0090.0569MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12254controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.heart massRS:0000817SS/Jrmale72 days to 70 days40CMO:0000069heart wet weight1.172g0.0170.1075MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12257controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.heart massRS:0000817SS/Jrmale72 days to 70 days20CMO:0000069heart wet weight1.209g0.0140.0626MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12260controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.heart massRS:0000817SS/Jrmale72 days to 70 days20CMO:0000069heart wet weight1.269g0.0150.0671MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12262controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.heart massRS:0000817SS/Jrmale72 days to 70 days20CMO:0000069heart wet weight1.119g0.0160.0716MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12275controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.heart massRS:0000817SS/Jrmale72 days to 70 days40CMO:0000069heart wet weight1.15g0.010.0632MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12279controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.body massRS:0000817SS/Jrmale72 days to 70 days40CMO:0000012body weight318.6g2.616.4438MMO:0000016body weighing methodcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12282controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.body massRS:0000817SS/Jrmale72 days to 70 days40CMO:0000012body weight298.6g2.012.6491MMO:0000016body weighing methodcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12285controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.body massRS:0000817SS/Jrmale72 days to 70 days20CMO:0000012body weight288.1g2.812.522MMO:0000016body weighing methodcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12287controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.body massRS:0000817SS/Jrmale72 days to 70 days20CMO:0000012body weight301.8g2.410.7331MMO:0000016body weighing methodcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12296controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.body massRS:0000817SS/Jrmale72 days to 70 days20CMO:0000012body weight304.7g2.19.3915MMO:0000016body weighing methodcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12299controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure231mmHg3.314.758MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12450controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure202mmHg1.727.6921MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12451controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure209mmHg2.9713.2822MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12452controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure222mmHg3.716.5469MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12453controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure221mmHg3.4415.3841MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12454controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure218mmHg3.8317.1283MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12455controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure235mmHg4.821.4663MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12456controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure209mmHg3.2614.5792MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12457controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressure191mmHg3.4815.563MMO:0000031tail cuff plethysmographyaverage of 3-4 consistent readingscontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12459controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight294g4.0217.978MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12483controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight318g3.5715.9655MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12484controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight309g3.4315.3394MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12485controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight314g1.727.6921MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12486controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight304g2.9513.1928MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12488controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight308g1.687.5132MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12489controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight302g3.2414.4897MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12490controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight305g4.0217.978MMO:0000016body weighing methodcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12492controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
261Grondin M, et al., Physiol Genomics 2005 Mar 21;21(1):112-6. Epub 2005 Jan 4.arterial blood pressure traitRS:0000817SS/Jrmale92 days to 88 days19CMO:0000009mean arterial blood pressuremeasure every 2 min for 24 hrs169mmHg4.017.4356MMO:0000070intra-aortic abdominal radiotelemetrycontrolled sodium content diet (2 %) (between 43 and 47 days)12422controlled sodium content diet (2 %) (between 43 and 47 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight304g2.611.6276MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12510controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.273g0.01450.065MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12511controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weightregression of heart weight on body weight1.206g0.02310.1033MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12515controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weightregression of heart weight on body weight1.312g0.01620.0726MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12516controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.251g0.01520.0681MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12517controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.278g0.01590.0713MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12518controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weightregression of heart weight on body weight1.208g0.01020.0456MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12519controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weightregression of heart weight on body weight1.291g0.0420.1878MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12521controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weightregression of heart weight on body weight1.291g0.01690.0754MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12522controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weightregression of heart weight on body weight1.1g0.01860.0832MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12523controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.334g/kg0.0420.1878MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12542controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio3.834g/kg0.0370.1655MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12543controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
269Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.arterial blood pressure traitRS:0000817SS/Jrmale56 days10CMO:0000009mean arterial blood pressure175mmHg4.012.6491MMO:0000070intra-aortic abdominal radiotelemetryaortacontrolled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days)12544controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 21 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.324g/kg0.0570.2549MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12545controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio3.985g/kg0.0420.1878MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12546controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.208g/kg0.0610.2728MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12547controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4g/kg0.0370.1655MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12549controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.346g/kg0.050.2236MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12553controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.223g/kg0.0580.2594MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12554controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
266Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio3.847g/kg0.0580.2594MMO:0000005post excision weight measurementcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days)12555controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)
231Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202arterial blood pressure traitRS:0000817SS/Jrmale68 days to 65 days24CMO:0000004systolic blood pressure205.8mmHg3.9119.155MMO:0000052tail cuff photoplethysmographytailaverage of 4 days, 3 to 4 consistent readings each day, IITCcontrolled sodium content diet (2 %) (between 25 and 28 days)12093controlled sodium content diet (2 %) (between 25 and 28 days)
231Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202arterial blood pressure traitRS:0000817SS/Jrmale68 days to 65 days21CMO:0000004systolic blood pressure209.8mmHg4.1118.8344MMO:0000052tail cuff photoplethysmographytailaverage of 4 days, 3 to 4 consistent readings each day, IITCcontrolled sodium content diet (2 %) (between 25 and 28 days)12099controlled sodium content diet (2 %) (between 25 and 28 days)
226Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161heart massRS:0000817SS/Jrmale98 days16CMO:0000074heart weight to body weight ratio4.1g/kg0.10.4MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 35 and 98 days)12124controlled sodium content diet (2 %) (between 35 and 98 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4arterial blood pressure traitRS:0000817SS/Jrmale68 days to 64 days20CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days204mmHg2.8412.7009MMO:0000031tail cuff plethysmographytail345600warm up to 28 Ccontrolled sodium content diet (2 %) (for 24 days)12127controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4arterial blood pressure traitRS:0000817SS/Jrmale68 days to 64 days20CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days209mmHg3.5115.6972MMO:0000031tail cuff plethysmographytail345600warm up to 28 Ccontrolled sodium content diet (2 %) (for 24 days)12128controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4arterial blood pressure traitRS:0000817SS/Jrmale68 days to 64 days20CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days195mmHg3.3514.9817MMO:0000031tail cuff plethysmographytail345600warm up to 28 Ccontrolled sodium content diet (2 %) (for 24 days)12129controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4arterial blood pressure traitRS:0000817SS/Jrmale68 days to 64 days20CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days210mmHg4.620.5718MMO:0000031tail cuff plethysmographytail345600warm up to 28 Ccontrolled sodium content diet (2 %) (for 24 days)12130controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4arterial blood pressure traitRS:0000817SS/Jrmale68 days to 64 days20CMO:0000004systolic blood pressureAverage of 3-4 consistent measurements taken each day over 4 consecutive days198mmHg3.9617.7097MMO:0000031tail cuff plethysmographytail345600warm up to 28 Ccontrolled sodium content diet (2 %) (for 24 days)12131controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4body massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000012body weight340g5.2623.5234MMO:0000016body weighing method0controlled sodium content diet (2 %) (for 24 days)12141controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4body massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000012body weight308g1.285.7243MMO:0000016body weighing method0controlled sodium content diet (2 %) (for 24 days)12142controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4body massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000012body weight312g3.2214.4003MMO:0000016body weighing method0controlled sodium content diet (2 %) (for 24 days)12143controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4body massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000012body weight306g3.0913.8189MMO:0000016body weighing method0controlled sodium content diet (2 %) (for 24 days)12144controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4body massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000012body weight307g2.029.0337MMO:0000016body weighing method0controlled sodium content diet (2 %) (for 24 days)12145controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000069heart wet weight1.45g0.040.1789MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12153controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000069heart wet weight1.31g0.010.0447MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12154controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000069heart wet weight1.18g0.010.0447MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12155controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000069heart wet weight1.25g0.010.0447MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12156controlled sodium content diet (2 %) (for 24 days)
232Saad Y, et al., Mamm Genome. 2008 Jan 4heart massRS:0000817SS/Jrmale68 days to 64 days20CMO:0000069heart wet weight1.17g0.010.0447MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)12157controlled sodium content diet (2 %) (for 24 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.body massRS:0000817SS/Jrmale72 days to 70 days41CMO:0000012body weight326.2g2.113.4466MMO:0000016body weighing methodcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12305controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.kidney massRS:0000817SS/Jrmale72 days to 70 days40CMO:0000085both kidneys wet weight3.081g0.0360.2277MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12312controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.kidney massRS:0000817SS/Jrmale72 days to 70 days40CMO:0000085both kidneys wet weight3.03g0.060.3795MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12314controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.kidney massRS:0000817SS/Jrmale72 days to 70 days20CMO:0000085both kidneys wet weight2.899g0.0510.2281MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12316controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.kidney massRS:0000817SS/Jrmale72 days to 70 days41CMO:0000085both kidneys wet weight3.037g0.030.1921MMO:0000005post excision weight measurementcontrolled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)12318controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
242Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 56 days10CMO:0000009mean arterial blood pressure170mmHg5.015.8114MMO:0000070intra-aortic abdominal radiotelemetrycontrolled sodium content diet (2 %) (between 21 and 37 days)12322controlled sodium content diet (2 %) (between 21 and 37 days)
246Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.body massRS:0000817SS/Jrmale84 days12CMO:0000012body weight375g6.020.7846MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) 12331controlled sodium content diet (0.3 %)
246Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.kidney massRS:0000817SS/Jrmale84 days12CMO:0000085both kidneys wet weight3.12g0.0490.1697MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) 12338controlled sodium content diet (0.3 %)
246Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.heart massRS:0000817SS/Jrmale84 days12CMO:0000069heart wet weight1.22g0.0190.0658MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) 12346controlled sodium content diet (0.3 %)
242Dutil J, et al., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 56 days18CMO:0000009mean arterial blood pressure170mmHg4.016.9706MMO:0000070intra-aortic abdominal radiotelemetrycontrolled sodium content diet (2 %) (between 21 and 37 days)12354controlled sodium content diet (2 %) (between 21 and 37 days)
246Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.blood triglyceride amountRS:0000817SS/Jrmale84 days to 28 days8CMO:0000360serum triglyceride level66mg/dl4.111.5966MMO:0000179automated blood analysiscontrolled sodium content diet (0.3 %) 12399controlled sodium content diet (0.3 %)
269Charron S, et al., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.arterial blood pressure traitRS:0000817SS/Jrmale56 days16CMO:0000009mean arterial blood pressure184mmHg4.016.0MMO:0000070intra-aortic abdominal radiotelemetryaortacontrolled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 21 days)12595controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 21 days)
272Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5.arterial blood pressure traitRS:0000817SS/Jrmale86 days to 82 days69CMO:0000009mean arterial blood pressure5 hr recording session - 1 min. averages, averaged over 4 daysserial mean187mmHgMMO:0000013vascular fluid filled catheterfemoral artery345600connected to solid-state transducer (Argon Medical Technologies, Athens, TX)controlled sodium content diet (8 %) (between 21 and 25 days)12613controlled sodium content diet (8 %) (between 21 and 25 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000069heart wet weight1.25g0.0080.0358MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12843controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000069heart wet weight1.2g0.0060.0268MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12844controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000069heart wet weight1.35g0.0090.0402MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12845controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days30CMO:0000069heart wet weight1.3g0.0130.0712MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12846controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000069heart wet weight1.25g0.1520.6798MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12848controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.body massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000012body weight314g2.239.9729MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12863controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.body massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000012body weight309g2.5311.3145MMO:0000016body weighing method0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12864controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.body massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000012body weight345g1.657.379MMO:0000016body weighing method0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12865controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.body massRS:0000817SS/Jrmale66 days to 64 days30CMO:0000012body weight328g2.6114.2956MMO:0000016body weighing method0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12866controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000074heart weight to body weight ratio4.04g/kg0.0290.1297MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12883controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000074heart weight to body weight ratio3.89g/kg0.0230.1029MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12884controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days20CMO:0000074heart weight to body weight ratio3.95g/kg0.0290.1297MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12885controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart massRS:0000817SS/Jrmale66 days to 64 days30CMO:0000074heart weight to body weight ratio3.98g/kg0.030.1643MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12886controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.arterial blood pressure traitRS:0000817SS/Jrmale75 days to 73 days10CMO:0000004systolic blood pressureaveerage of 4-hour interval averages over 4 days211mmHg2.056.4827MMO:0000015radiotelemetry345600C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days)12915controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 33 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.arterial blood pressure traitRS:0000817SS/Jrmale75 days to 73 days10CMO:0000005diastolic blood pressureaveerage of 4-hour interval averages over 4 days162mmHg1.675.281MMO:0000015radiotelemetry345600C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days)12920controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 33 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.arterial blood pressure traitRS:0000817SS/Jrmale75 days to 73 days10CMO:0000292pulse pressureaveerage of 4-hour interval averages over 4 days58mmHg0.381.2017MMO:0000015radiotelemetry345600C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days)12922controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 33 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.heart pumping traitRS:0000817SS/Jrmale75 days to 73 days10CMO:0000002heart rateaveerage of 4-hour interval averages over 4 daysserial mean407beats/min4.012.6491MMO:0000015radiotelemetry345600C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days)12925controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 33 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days20CMO:0000004systolic blood pressureaverage of 2-3 readings/day over 4 days203mmHg2.9813.327MMO:0000031tail cuff plethysmography4semi- automatic equipment from IITC, Woodland Hills, CAcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12809controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
313Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7.arterial blood pressure traitRS:0000817SS/Jrmale66 days to 64 days30CMO:0000004systolic blood pressureaverage of 2-3 readings/day over 4 days198mmHg1.789.7495MMO:0000031tail cuff plethysmography4semi- automatic equipment from IITC, Woodland Hills, CAcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)12810controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000005diastolic blood pressureaverage of 12 4-hour averages over 48 hours using 5 or 6 ratsserial mean130mmHg1.573.5106MMO:0000070intra-aortic abdominal radiotelemetrylower abdominal aorta172800C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (2 %) (between 35 and 37 days)13031controlled sodium content diet (2 %) (between 35 and 37 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000009mean arterial blood pressureaverage of 12 4-hour averages over 48 hours using 5 or 6 ratsserial mean158mmHg1.763.9355MMO:0000070intra-aortic abdominal radiotelemetrylower abdominal aorta172800C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (2 %) (between 35 and 37 days)13035controlled sodium content diet (2 %) (between 35 and 37 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.total urine protein amountRS:0000817SS/Jrmale73 days to 71 days20CMO:0000756urine total protein excretion rate91.29mg/d6.0527.0564MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout86400controlled sodium content diet (2 %) (between 31 and 32 days)64992controlled sodium content diet (2 %) (between 31 and 32 days)
328Moujahidine M, et al., Mamm Genome 2002 Mar;13(3):153-6.arterial blood pressure traitRS:0000817SS/Jrmale71 days to 56 days11CMO:0000009mean arterial blood pressureaverage of 6 measurements taken every 4 hrsserial mean184mmHg5.016.5831MMO:0000070intra-aortic abdominal radiotelemetryaorta0controlled sodium content diet (2 %) (between 21 and 36 days)13078controlled sodium content diet (2 %) (between 21 and 36 days)
335Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16.urine albumin amountRS:0000817SS/Jrnot specified28 days12CMO:0000757urine albumin excretion rate4.7mg/dMMO:0000075enzyme linked immunosorbent assayurine0.0rat albumin ELISAcontrolled sodium content diet (0.2 %) 13281controlled sodium content diet (0.2 %)
335Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16.urine albumin amountRS:0000817SS/Jrnot specified196 days12CMO:0000757urine albumin excretion rate148.47mg/dMMO:0000075enzyme linked immunosorbent assayurine0.0rat albumin ELISAcontrolled sodium content diet (0.2 %) 13283controlled sodium content diet (0.2 %)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight316g3.9317.5755MMO:0000016body weighing methodcontrolled sodium content diet (2 %) (for 28 days)12942controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight311g1.637.2896MMO:0000016body weighing methodcontrolled sodium content diet (2 %) (for 28 days)12944controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight339g3.013.4164MMO:0000016body weighing methodcontrolled sodium content diet (2 %) (for 28 days)12945controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight318g2.099.3468MMO:0000016body weighing methodcontrolled sodium content diet (2 %) (for 28 days)12947controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight343g5.223.2551MMO:0000016body weighing methodcontrolled sodium content diet (2 %) (for 28 days)12948controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.body massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000012body weight316g2.8312.6561MMO:0000016body weighing methodcontrolled sodium content diet (2 %) (for 28 days)12950controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.31g0.0170.076MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12958controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.3g0.0120.0537MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12960controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days3CMO:0000069heart wet weight1.48g0.0670.116MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12961controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days16CMO:0000069heart wet weight1.33g0.0230.092MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12963controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days6CMO:0000069heart wet weight1.39g0.0330.0808MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12964controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000069heart wet weight1.4g0.0260.1163MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12966controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.17g/kg0.0630.2817MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12974controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.19g/kg0.0440.1968MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12978controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days3CMO:0000074heart weight to body weight ratio4.32g/kg0.240.4157MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12984controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days16CMO:0000074heart weight to body weight ratio4.18g/kg0.0670.268MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12987controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days6CMO:0000074heart weight to body weight ratio4.04g/kg0.080.196MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12989controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart massRS:0000817SS/Jrmale70 days to 68 days20CMO:0000074heart weight to body weight ratio4.44g/kg0.0920.4114MMO:0000005post excision weight measurementcontrolled sodium content diet (2 %) (for 28 days)12991controlled sodium content diet (2 %) (for 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 3 averaged readings per day over 4 daysserial mean207mmHg4.118.3358MMO:0000052tail cuff photoplethysmographytail34560028 degrees Ccontrolled sodium content diet (2 %) (between 24 and 28 days)13000controlled sodium content diet (2 %) (between 24 and 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 3 averaged readings per day over 4 daysserial mean213mmHg4.8521.6899MMO:0000052tail cuff photoplethysmographytail34560028 degrees Ccontrolled sodium content diet (2 %) (between 24 and 28 days)13011controlled sodium content diet (2 %) (between 24 and 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 3 averaged readings per day over 4 daysserial mean213mmHg4.6320.706MMO:0000052tail cuff photoplethysmographytail34560028 degrees Ccontrolled sodium content diet (2 %) (between 24 and 28 days)13013controlled sodium content diet (2 %) (between 24 and 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days16CMO:0000004systolic blood pressureaverage of 3 averaged readings per day over 4 daysserial mean205mmHg4.9119.64MMO:0000052tail cuff photoplethysmographytail34560028 degrees Ccontrolled sodium content diet (2 %) (between 24 and 28 days)13015controlled sodium content diet (2 %) (between 24 and 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 3 averaged readings per day over 4 daysserial mean203mmHg4.1118.3805MMO:0000052tail cuff photoplethysmographytail34560028 degrees Ccontrolled sodium content diet (2 %) (between 24 and 28 days)13016controlled sodium content diet (2 %) (between 24 and 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 3 averaged readings per day over 4 daysserial mean214mmHg5.6125.0887MMO:0000052tail cuff photoplethysmographytail34560028 degrees Ccontrolled sodium content diet (2 %) (between 24 and 28 days)13018controlled sodium content diet (2 %) (between 24 and 28 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.arterial blood pressure traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000004systolic blood pressureaverage of 12 4-hour averages over 48 hours using 5 or 6 ratsserial mean185mmHg1.974.4051MMO:0000070intra-aortic abdominal radiotelemetrylower abdominal aorta172800C-40 transmitter (Data Sciences International, St. Paul, MN)controlled sodium content diet (2 %) (between 35 and 37 days)13026controlled sodium content diet (2 %) (between 35 and 37 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean242mmHg3.716.5469MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)13082controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean218mmHg3.113.8636MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)13083controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean215mmHg3.7216.6363MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)13084controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean191mmHg1.587.066MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)13085controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days44CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean190mmHg1.6110.6795MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days)13116controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 24 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean189mmHg2.9213.0586MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)13117controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean196mmHg2.5311.3145MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)13119controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
282Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days30CMO:0000004systolic blood pressureaverage of 4 daily averages of 3-4 measurements/dayserial mean206mmHg2.2312.2142MMO:0000052tail cuff photoplethysmographytail345600controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)13125controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
335Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16.urine albumin amountRS:0000817SS/Jrnot specified98 days6CMO:0000757urine albumin excretion rate253.07mg/dMMO:0000075enzyme linked immunosorbent assayurine0.0rat albumin ELISAcontrolled sodium content diet (0.2 %) 13278controlled sodium content diet (0.2 %)
344Huang BS, et al., Hypertension. 2007 Apr 9;.body massRS:0000817SS/Jrmale52 days to 43 days12CMO:0000420body weight gain51g2.06.9282MMO:0000016body weighing methodcontrolled sodium content diet (8 %) (between 8 and 10 days)13318controlled sodium content diet (8 %) (between 8 and 10 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.blood sodium amountRS:0000817SS/Jrmale52 days to 43 days12CMO:0000060plasma sodium level147mmol/l2.06.9282MMO:0000452sodium ion-selective electrode methodsodium ion-selective electrodecontrolled sodium content diet (8 %) (between 8 and 10 days)13322controlled sodium content diet (8 %) (between 8 and 10 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.blood potassium amountRS:0000817SS/Jrmale52 days to 43 days12CMO:0000061plasma potassium level5.1mmol/l0.31.0392MMO:0000453potassium ion-selective electrode methodpotassium ion-selective electrodecontrolled sodium content diet (8 %) (between 8 and 10 days)13326controlled sodium content diet (8 %) (between 8 and 10 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.blood chloride amountRS:0000817SS/Jrmale52 days to 43 days12CMO:0000059plasma chloride level105mmol/l2.06.9282MMO:0000451chloride ion-selective electrode methodchloride ion-selective electrodecontrolled sodium content diet (8 %) (between 8 and 10 days)13330controlled sodium content diet (8 %) (between 8 and 10 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.erythrocyte quantityRS:0000817SS/Jrmale52 days to 43 days12CMO:0000037hematocrit40%3.010.3923MMO:0000032automated standard complete blood count (CBC) test0.0controlled sodium content diet (8 %) (between 8 and 10 days)13334controlled sodium content diet (8 %) (between 8 and 10 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days20CMO:0000004systolic blood pressure222mmHg5.0122.4054MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67311controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 63 days20CMO:0000004systolic blood pressureaverage of 4days210mmHg3.314.758MMO:0000031tail cuff plethysmography0controlled sodium content diet (2 %) (between 24 and 28 days)65479controlled sodium content diet (2 %) (between 24 and 28 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 63 days20CMO:0000004systolic blood pressureaverage of 4days216mmHg5.122.8079MMO:0000031tail cuff plethysmography0controlled sodium content diet (2 %) (between 24 and 28 days)65480controlled sodium content diet (2 %) (between 24 and 28 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 63 days20CMO:0000004systolic blood pressureaverage of 4days191mmHg3.515.6525MMO:0000031tail cuff plethysmography0controlled sodium content diet (2 %) (between 24 and 28 days)65481controlled sodium content diet (2 %) (between 24 and 28 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 63 days20CMO:0000004systolic blood pressureaverage of 4days206mmHg4.218.783MMO:0000031tail cuff plethysmography0controlled sodium content diet (2 %) (between 24 and 28 days)65482controlled sodium content diet (2 %) (between 24 and 28 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 63 days20CMO:0000004systolic blood pressureaverage of 4days202mmHg4.118.3358MMO:0000031tail cuff plethysmography0controlled sodium content diet (2 %) (between 24 and 28 days)65483controlled sodium content diet (2 %) (between 24 and 28 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.heart pumping traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000002heart ratediurnal difference390beats/min4.111.5966MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65503controlled sodium content diet (2 %) (between 34 and 38 days)
691Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.body massRS:0000817SS/Jrmale53 days10CMO:0000012body weight222g5.116.1276MMO:0000016body weighing method0controlled sodium content diet66105controlled sodium content diet
691Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.body massRS:0000817SS/Jrmale67 days to 53 days10CMO:0000012body weight297g5.015.8114MMO:0000016body weighing method0controlled sodium content diet (4 %) (for 14 days)66107controlled sodium content diet (4 %) (for 14 days)
691Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.body massRS:0000817SS/Jrmale81 days to 53 days10CMO:0000012body weight344g5.116.1276MMO:0000016body weighing method0controlled sodium content diet (4 %) (for 28 days)66109controlled sodium content diet (4 %) (for 28 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23body mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days46CMO:0000012body weight302g1.812.2082MMO:0000016body weighing method0controlled sodium content diet (2 %) (between 24 and 27 days)64713controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23body mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days40CMO:0000012body weight304g1.610.1193MMO:0000016body weighing method0controlled sodium content diet (2 %) (between 24 and 27 days)64716controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23body mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days20CMO:0000012body weight290g1.98.4971MMO:0000016body weighing method0controlled sodium content diet (2 %) (between 24 and 27 days)64718controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23body mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days19CMO:0000012body weight299g4.017.4356MMO:0000016body weighing method0controlled sodium content diet (2 %) (between 24 and 27 days)64727controlled sodium content diet (2 %) (between 24 and 27 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.heart left ventricle wall thicknessRS:0000817SS/Jrmale112 days to 109 days4CMO:0000988heart left ventricle relative wall thickness(SWT+PWT)/LVDd67%1.02.0MMO:0000002transthoracic echocardiography0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)65758controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 29 days)controlled sodium content diet (4 %) (between 40 and 41 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale69 days to 67 days5CMO:0000004systolic blood pressure181mmHg3.68.0498MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days)65041controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 27 and 28 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale78 days to 76 days5CMO:0000004systolic blood pressure217.9mmHg2.14.6957MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days)65044controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 9 and 10 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale109 days to 107 days3CMO:0000004systolic blood pressure228.2mmHg2.64.5033MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days)65047controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 39 and 40 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale116 days to 114 days3CMO:0000004systolic blood pressure219.3mmHg4.27.2746MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days)65050controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 47 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale149 days to 147 days1CMO:0000004systolic blood pressure219.7mmHg1.71.7MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days)65053controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 79 and 80 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale69 days to 67 days5CMO:0000005diastolic blood pressure125.2mmHg3.06.7082MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days)65057controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 27 and 28 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale78 days to 76 days4CMO:0000005diastolic blood pressure153mmHg1.63.2MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days)65060controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 9 and 10 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale109 days to 107 days3CMO:0000005diastolic blood pressure164.9mmHg2.33.9837MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days)65063controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 39 and 40 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale116 days to 114 days3CMO:0000005diastolic blood pressure158.2mmHg3.96.755MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days)65066controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 47 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale149 days to 147 days1CMO:0000005diastolic blood pressure152.5mmHg1.71.7MMO:0000070intra-aortic abdominal radiotelemetry86400controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days)65069controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 79 and 80 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.arterial blood pressure traitRS:0000817SS/Jrmale87 days to 85 days19CMO:0000004systolic blood pressure257.2mmHg5.122.2304MMO:0000052tail cuff photoplethysmography172800controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 17 and 18 days)65072controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 17 and 18 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.blood urea nitrogen amountRS:0000817SS/Jrmale118 days to 114 days4CMO:0000586plasma urea nitrogen level9.9mmol/l2.14.2MMO:0000307plasma urea nitrogen analysis0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days)65088controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 48 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.blood glucose amountRS:0000817SS/Jrmale118 days to 114 days4CMO:0000042plasma glucose level142.2mg/dl19.839.6MMO:0000112blood glucose analysis0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days)65092controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 48 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.body massRS:0000817SS/Jrmale118 days to 114 days4CMO:0000012body weight357g26.052.0MMO:0000016body weighing method0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days)65096controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 48 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.kidney massRS:0000817SS/Jrmale118 days to 114 days4CMO:0000340both kidneys wet weight to body weight ratio11.87g/kg0.921.84MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days)65100controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 48 days)
565Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 64 days20CMO:0000004systolic blood pressureserial mean207mmHg4.721.019MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65305controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days0CMO:0000004systolic blood pressure194mmHg7.36MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67509controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days0CMO:0000004systolic blood pressure197mmHg3.53MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67511controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000005diastolic blood pressureaverage of 24 hr147mmHg5.515.5563MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65494controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000292pulse pressureaverage of 24 hr52mmHg3.49.6167MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65495controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000004systolic blood pressureaverage of 24 hr199mmHg5.014.1421MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65493controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000009mean arterial blood pressureaverage of 24 hr172mmHg5.014.1421MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days)65496controlled sodium content diet (2 %) (between 34 and 38 days)
611Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84.arterial blood pressure traitRS:0000817SS/Jrmale80 days to 73 days8CMO:0000607absolute change in systolic blood pressurediurnal difference22.6mmHg1.052.9698MMO:0000070intra-aortic abdominal radiotelemetry10controlled sodium content diet (2 %) (between 34 and 38 days) then controlled exposure to darkness then controlled exposure to ambient light65497controlled sodium content diet (2 %) (between 34 and 38 days)controlled exposure to darknesscontrolled exposure to ambient light
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days0CMO:0000004systolic blood pressure197mmHg3.85MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67513controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days0CMO:0000004systolic blood pressure214mmHg5.26MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67515controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days0CMO:0000004systolic blood pressure263mmHg5.6MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67517controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days0CMO:0000004systolic blood pressure200mmHg4.22MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67521controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.arterial blood pressure traitRS:0000817SS/Jrnot specified70 days to 65 days0CMO:0000004systolic blood pressure213mmHg5.14MMO:0000031tail cuff plethysmography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67524controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.body massRS:0000817SS/Jrnot specified0 days0CMO:0000012body weight307g4.93MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67527controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.body massRS:0000817SS/Jrnot specified0 days0CMO:0000012body weight312g2.8MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67529controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.body massRS:0000817SS/Jrnot specified0 days0CMO:0000012body weight334g5.6MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67531controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.body massRS:0000817SS/Jrnot specified0 days0CMO:0000012body weight296g14.72MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67533controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.body massRS:0000817SS/Jrnot specified0 days0CMO:0000012body weight353g6.24MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67537controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.body massRS:0000817SS/Jrnot specified0 days0CMO:0000012body weight367g6.23MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days)67540controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 25 and 28 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000069heart wet weight1.28g0.018MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67543controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000069heart wet weight1.27g0.02MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67546controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000069heart wet weight1.38g0.016MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67550controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000069heart wet weight1.68g0.058MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67552controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000069heart wet weight1.53g0.019MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67556controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000069heart wet weight1.55g0.019MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67559controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000074heart weight to body weight ratio4.19g/kg0.081MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67562controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000074heart weight to body weight ratio4.09g/kg0.079MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67564controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000074heart weight to body weight ratio4.16g/kg0.065MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67566controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000074heart weight to body weight ratio5.82g/kg0.423MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67568controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000074heart weight to body weight ratio4.36g/kg0.073MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67572controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart massRS:0000817SS/Jrnot specified0 days0CMO:0000074heart weight to body weight ratio4.24g/kg0.098MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 67575controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
246Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.blood cholesterol amountRS:0000817SS/Jrmale84 days8CMO:0000363serum total cholesterol level119mg/dl5.314.9907MMO:0000179automated blood analysis0controlled sodium content diet (0.3 %) 64814controlled sodium content diet (0.3 %)
246Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.blood albumin amountRS:0000817SS/Jrmale84 days8CMO:0000550serum albumin level2.9g/dl0.060.1697MMO:0000179automated blood analysis0controlled sodium content diet (0.3 %) 64820controlled sodium content diet (0.3 %)
246Packard M, et al., Am J Physiol Renal Physiol. 2009 Apr;296(4):F839-46. Epub 2009 Jan 28.blood uric acid amountRS:0000817SS/Jrmale84 days8CMO:0000501blood uric acid level2.8mg/dl0.110.3111MMO:0000179automated blood analysis0controlled sodium content diet (0.3 %) 65784controlled sodium content diet (0.3 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.total urine protein amountRS:0000817SS/Jrnot specified83 days to 78 days0CMO:0000756urine total protein excretion rate78mg/d13.86MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout0.0controlled sodium content diet (2 %) (between 30 and 33 days)67578controlled sodium content diet (2 %) (between 30 and 33 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.total urine protein amountRS:0000817SS/Jrnot specified83 days to 78 days0CMO:0000756urine total protein excretion rate102mg/d6.81MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout0.0controlled sodium content diet (2 %) (between 30 and 33 days)67580controlled sodium content diet (2 %) (between 30 and 33 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.total urine protein amountRS:0000817SS/Jrnot specified83 days to 78 days0CMO:0000756urine total protein excretion rate127mg/d10.32MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout0.0controlled sodium content diet (2 %) (between 30 and 33 days)67582controlled sodium content diet (2 %) (between 30 and 33 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.total urine protein amountRS:0000817SS/Jrnot specified83 days to 78 days0CMO:0000756urine total protein excretion rate94mg/d7.54MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout0.0controlled sodium content diet (2 %) (between 30 and 33 days)67584controlled sodium content diet (2 %) (between 30 and 33 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.total urine protein amountRS:0000817SS/Jrnot specified83 days to 78 days0CMO:0000756urine total protein excretion rate253mg/d20.37MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout0.0controlled sodium content diet (2 %) (between 30 and 33 days)67586controlled sodium content diet (2 %) (between 30 and 33 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.total urine protein amountRS:0000817SS/Jrnot specified83 days to 78 days0CMO:0000756urine total protein excretion rate102mg/d6.81MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout0.0controlled sodium content diet (2 %) (between 30 and 33 days)67588controlled sodium content diet (2 %) (between 30 and 33 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.total urine protein amountRS:0000817SS/Jrnot specified83 days to 78 days0CMO:0000756urine total protein excretion rate160mg/d6.78MMO:0000332pyrogallol red-molybdate complex-based urine total protein analysis with spectrophotometric readout0.0controlled sodium content diet (2 %) (between 30 and 33 days)67590controlled sodium content diet (2 %) (between 30 and 33 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.artery morphology traitRS:0000817SS/Jrmale118 days to 114 days3CMO:0000979artery wall thickness to artery inner diameter ratio54%7.012.1244MMO:0000111ex vivo light microscopy0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days)65738controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 48 days)
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87kidney massRS:0000817SS/Jrmale183 days6CMO:0000160calculated kidney weightadjusted organ weight for differences in body weight by regression analysis using programs from SPSS3.306g0.140.3429MMO:0000005post excision weight measurement0naive control condition65450naive control condition
226Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161kidney massRS:0000817SS/Jrmale98 days16CMO:0000340both kidneys wet weight to body weight ratio12.1g/kg0.31.2MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 35 and 98 days)64772controlled sodium content diet (2 %) (between 35 and 98 days)
565Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 66 days20CMO:0000004systolic blood pressureserial mean190mmHg5.424.1495MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 36 and 40 days)65309controlled sodium content diet (0.4 %) (between 36 and 40 days)
565Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.heart massRS:0000817SS/Jrmale70 days to 66 days20CMO:0000069heart wet weightserial mean1.276g0.01730.0771MMO:0000005post excision weight measurement345600/controlled sodium content diet (0.4 %) (between 36 and 40 days)65313controlled sodium content diet (0.4 %) (between 36 and 40 days)
565Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7.heart massRS:0000817SS/Jrmale70 days to 64 days20CMO:0000069heart wet weightserial mean1.321g0.01250.0561MMO:0000005post excision weight measurement345600controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65314controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.heart left ventricle diameterRS:0000817SS/Jrmale112 days to 109 days6CMO:0000982heart left ventricular end-diastolic diameter7.4mm0.40.9798MMO:0000002transthoracic echocardiography0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)65741controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 29 days)controlled sodium content diet (4 %) (between 40 and 41 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.heart left ventricle diameterRS:0000817SS/Jrmale112 days to 109 days6CMO:0000983heart left ventricle end-systolic diameter4.2mm0.40.9798MMO:0000002transthoracic echocardiography0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)65745controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 29 days)controlled sodium content diet (4 %) (between 40 and 41 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.heart left ventricle diameterRS:0000817SS/Jrmale112 days to 109 days6CMO:0000985heart left ventricle fractional shortening44%4.09.798MMO:0000002transthoracic echocardiography0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)65749controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 29 days)controlled sodium content diet (4 %) (between 40 and 41 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.heart muscle contractility traitRS:0000817SS/Jrmale112 days to 109 days6CMO:0000994velocity of circumferential fiber shortening548%/s59.0144.5199MMO:0000002transthoracic echocardiography0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days)65753controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 29 days)controlled sodium content diet (4 %) (between 40 and 41 days)
615Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8.arterial blood pressure traitRS:0000817SS/Jrmale77 days to 66 days15CMO:0000004systolic blood pressuremeasurement taken every 4 hours during a 24-hour periodserial mean203mmHg4.015.4919MMO:0000015radiotelemetry86400.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days)65536controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 42 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.body massRS:0000817SS/Jrmale42 days to 40 days20CMO:0000012body weight161g2.19.3915MMO:0000016body weighing method0controlled sodium content diet (0.3 %) (between 10 and 12 days)65024controlled sodium content diet (0.3 %) (between 10 and 12 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left ventricle posterior wall thicknessRS:0000817SS/Jrmale77 days40CMO:0000239heart left ventricle posterior wall thickness0.185mm0.00320.02MMO:0000002transthoracic echocardiography0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)65115controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.kidney massRS:0000817SS/Jrmale118 days to 114 days4CMO:0000085both kidneys wet weight4.17g0.140.28MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days)65122controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (for 28 days)controlled sodium content diet (4 %) (between 46 and 48 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.heart massRS:0000817SS/Jrmale118 days to 114 days4CMO:0000069heart wet weight1.67g0.070.14MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 0 and 672 hours) then controlled sodium content diet (4 %) (between 46 and 48 days)65129controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 0 and 672 hours)controlled sodium content diet (4 %) (between 46 and 48 days)
283Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2.heart massRS:0000817SS/Jrmale118 days to 114 days4CMO:0000074heart weight to body weight ratio4.76g/kg0.460.92MMO:0000005post excision weight measurement0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 0 and 672 hours) then controlled sodium content diet (4 %) (between 46 and 48 days)65133controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 0 and 672 hours)controlled sodium content diet (4 %) (between 46 and 48 days)
563Crespo K, et al., J Hypertens. 2011 Mar;29(3):460-5.arterial blood pressure traitRS:0000817SS/Jrmale73 days to 66 days14CMO:0000009mean arterial blood pressure178mmHg4.014.9666MMO:0000070intra-aortic abdominal radiotelemetry0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (between 31 and 49 days)65147controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (between 31 and 49 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23arterial blood pressure traitRS:0000817SS/Jrnot specified71 days to 64 days40CMO:0000004systolic blood pressureserial mean216mmHg2.415.1789MMO:0000031tail cuff plethysmographytail0controlled sodium content diet (2 %) (between 24 and 27 days)64736controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23arterial blood pressure traitRS:0000817SS/Jrnot specified71 days to 64 days46CMO:0000004systolic blood pressureserial mean207mmHg2.214.9211MMO:0000031tail cuff plethysmographytail0controlled sodium content diet (2 %) (between 24 and 27 days)64733controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23heart mass4 rats per cage, 2 SR/Jr 2 LEW/NCrlRS:0000817SS/Jrnot specified71 days to 64 days40CMO:0000069heart wet weight1.235g0.00790.05MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (between 24 and 27 days)64747controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23arterial blood pressure traitRS:0000817SS/Jrnot specified71 days to 64 days20CMO:0000004systolic blood pressureserial mean219mmHg3.415.2053MMO:0000031tail cuff plethysmographytail0controlled sodium content diet (2 %) (between 24 and 27 days)64738controlled sodium content diet (2 %) (between 24 and 27 days)
222Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23arterial blood pressure traitRS:0000817SS/Jrnot specified71 days to 64 days19CMO:0000004systolic blood pressureserial mean205mmHg5.925.7175MMO:0000031tail cuff plethysmographytail0controlled sodium content diet (2 %) (between 24 and 27 days)64741controlled sodium content diet (2 %) (between 24 and 27 days)
305Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41.heart pumping traitRS:0000817SS/Jrmale79 days to 75 days5CMO:0000002heart rate378beats/min9.1820.5271MMO:0000070intra-aortic abdominal radiotelemetry172800controlled sodium content diet (2 %) (for 37 days)64986controlled sodium content diet (2 %) (for 37 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.arterial blood pressure traitRS:0000817SS/Jrmale60 days to 56 days12CMO:0000009mean arterial blood pressuretwo 24 hours widely separated periods, data represent averages of all readings over the 24-h measurements178mmHg1.15474.0MMO:0000015radiotelemetry86400controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 23 days)65002controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 23 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.body massRS:0000817SS/Jrmale77 days40CMO:0000012body weight305.6g4.379827.7MMO:0000016body weighing method0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)65005controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart pumping traitRS:0000817SS/Jrmale77 days40CMO:0000002heart rate414beats/min4.269127.0MMO:0000002transthoracic echocardiography0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)65013controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left ventricle massRS:0000817SS/Jrmale77 days40CMO:0000071heart left ventricle wet weight0.907g0.01420.09MMO:0000005post excision weight measurement0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)65028controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
615Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8.arterial blood pressure traitRS:0000817SS/Jrmale77 days to 66 days15CMO:0000005diastolic blood pressuremeasurement taken every 4 hours during a 24-hour periodserial mean150mmHg4.015.4919MMO:0000015radiotelemetry86400.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days)65553controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 42 days)
615Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8.arterial blood pressure traitRS:0000817SS/Jrmale77 days to 66 days15CMO:0000009mean arterial blood pressuremeasurement taken every 4 hours during a 24-hour periodserial mean175mmHg3.011.619MMO:0000015radiotelemetry86400.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days)65559controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 42 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days40CMO:0000004systolic blood pressureserial mean213mmHg2.515.8114MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65790controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days40CMO:0000004systolic blood pressureserial mean218.3mmHg2.616.4438MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65791controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days20CMO:0000004systolic blood pressureserial mean210.6mmHg3.415.2053MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65792controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days20CMO:0000004systolic blood pressureserial mean206.6mmHg2.410.7331MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65793controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days20CMO:0000004systolic blood pressureserial mean203.6mmHg4.218.783MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65794controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days41CMO:0000004systolic blood pressureserial mean204.7mmHg2.113.4466MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65795controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days19CMO:0000004systolic blood pressureserial mean190.9mmHg3.615.692MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65800controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
237Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13.arterial blood pressure traitRS:0000817SS/Jrmale72 days to 64 days39CMO:0000004systolic blood pressureserial mean191.8mmHg2.616.237MMO:0000031tail cuff plethysmography345600Rats warmed to 28 degrees C for measurement.controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days)65801controlled sodium content diet (0.4 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 24 and 28 days)
633Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6arterial blood pressure traitRS:0000817SS/Jrmale62 days20CMO:0000004systolic blood pressureonly mentioned blood pressure195mmHg2.712.0748MMO:0000031tail cuff plethysmography0controlled sodium content diet (2 %) (for 24 days)65829controlled sodium content diet (2 %) (for 24 days)
633Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6body massRS:0000817SS/Jrmale62 days20CMO:0000012body weight324g2.511.1803MMO:0000016body weighing method0controlled sodium content diet (2 %) (for 24 days)65831controlled sodium content diet (2 %) (for 24 days)
633Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6heart massRS:0000817SS/Jrmale62 days20CMO:0000069heart wet weight1.364g0.01370.0613MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)65834controlled sodium content diet (2 %) (for 24 days)
633Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6heart massRS:0000817SS/Jrmale62 days20CMO:0000073calculated heart weightheart weight adjusted for differences in body weight1.348g0.01320.059MMO:0000005post excision weight measurement0controlled sodium content diet (2 %) (for 24 days)65836controlled sodium content diet (2 %) (for 24 days)
650Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41arterial blood pressure traitRS:0000817SS/Jrboth134 days to 131 days21CMO:0000004systolic blood pressuredata obtained at three consistent sessions per dayserial mean244mmHgMMO:0000031tail cuff plethysmography345600controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (between 41 and 44 days)65963controlled sodium content diet (1 %) (for 60 days)controlled sodium content diet (0.2 %) (between 41 and 44 days)
650Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41heart massRS:0000817SS/Jrmale134 days21CMO:0000074heart weight to body weight ratio3.68g/kgMMO:0000005post excision weight measurement0controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (for 40 days)65965controlled sodium content diet (1 %) (for 60 days)controlled sodium content diet (0.2 %) (for 40 days)
650Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41arterial blood pressure traitRS:0000817SS/Jrboth68 days to 65 days20CMO:0000004systolic blood pressuredata obtained at three consistent sessions per dayserial mean199mmHgMMO:0000031tail cuff plethysmography345600controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 25 and 28 days)65967controlled sodium content diet (0.2 %) (for 10 days)controlled sodium content diet (2 %) (between 25 and 28 days)
650Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41arterial blood pressure traitRS:0000817SS/Jrmale84 days to 81 days20CMO:0000004systolic blood pressuredata obtained at three consistent sessions per dayserial mean231mmHgMMO:0000031tail cuff plethysmography345600controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 41 and 44 days)65971controlled sodium content diet (0.2 %) (for 10 days)controlled sodium content diet (2 %) (between 41 and 44 days)
650Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41arterial blood pressure traitRS:0000817SS/Jrboth68 days to 65 days38CMO:0000004systolic blood pressuredata obtained at three consistent sessions per dayserial mean260mmHgMMO:0000031tail cuff plethysmography345600controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (4 %) (between 24 and 28 days)65974controlled sodium content diet (0.2 %) (for 10 days)controlled sodium content diet (4 %) (between 24 and 28 days)
650Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41arterial blood pressure traitRS:0000817SS/Jrnot specified68 days to 65 days27CMO:0000004systolic blood pressuredata obtained at three consistent sessions per dayserial mean211mmHgMMO:0000031tail cuff plethysmography345600controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days)66028controlled sodium content diet (0.2 %) (for 24 days)controlled sodium content diet (4 %) (for 24 days)
650Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41heart massRS:0000817SS/Jrnot specified68 days27CMO:0000074heart weight to body weight ratio4.05g/kgMMO:0000005post excision weight measurement0controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (for 24 days)66031controlled sodium content diet (0.2 %) (for 10 days)controlled sodium content diet (2 %) (for 24 days)
691Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.arterial blood pressure traitRS:0000817SS/Jrmale53 days10CMO:0000004systolic blood pressure151mmHg5.116.1276MMO:0000031tail cuff plethysmography0controlled sodium content diet66115controlled sodium content diet
691Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.arterial blood pressure traitRS:0000817SS/Jrmale67 days10CMO:0000004systolic blood pressure218mmHg7.824.6658MMO:0000031tail cuff plethysmography0controlled sodium content diet (4 %) (for 14 days)66117controlled sodium content diet (4 %) (for 14 days)
691Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8.arterial blood pressure traitRS:0000817SS/Jrmale81 days10CMO:0000004systolic blood pressure238mmHg7.022.1359MMO:0000031tail cuff plethysmography0controlled sodium content diet (4 %) (for 28 days)66119controlled sodium content diet (4 %) (for 28 days)
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87body massRS:0000817SS/Jrmale57 days to 56 days6CMO:0000012body weight293g9.824.005MMO:0000016body weighing method0naive control condition65440naive control condition
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87body massRS:0000817SS/Jrmale85 days to 84 days6CMO:0000012body weight384g8.921.8005MMO:0000016body weighing method0naive control condition65442naive control condition
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87body massRS:0000817SS/Jrmale141 days to 140 days6CMO:0000012body weight451g18.545.3156MMO:0000016body weighing method0naive control condition65444naive control condition
104Garrett MR, et al., J Am Soc Nephrol 2003 May;14(5):1175-87body massRS:0000817SS/Jrmale183 days to 182 days6CMO:0000012body weight485g11.929.1489MMO:0000016body weighing method0naive control condition65446naive control condition
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left ventricle massRS:0000817SS/Jrmale77 days40CMO:0000530heart left ventricle weight to body weight ratio2.99mg/g0.06010.38MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68258controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left ventricle diameterRS:0000817SS/Jrmale77 days40CMO:0000982heart left ventricular end-diastolic diameter7.18mm0.09010.57MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68266controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left ventricle diameterRS:0000817SS/Jrmale77 days40CMO:0000983heart left ventricle end-systolic diameter3.55mm0.08850.56MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68274controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left ventricle diameterRS:0000817SS/Jrmale77 days40CMO:0000985heart left ventricle fractional shortening(LVDdLVDs)/LVDd x 10050.7%0.83015.25MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68282controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart pumping traitRS:0000817SS/Jrmale77 days40CMO:0000180ejection fractionpeak aortic velocity86%0.65464.14MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68290controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart left ventricle size traitRS:0000817SS/Jrnot specified0 days6CMO:0001191heart left ventricle end-diastolic area0.62cm20.110.2694MMO:0000337echocardiography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 69596controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
344Huang BS, et al., Hypertension. 2007 Apr 9;.cerebrospinal fluid mineral amountRS:0000817SS/Jrmale52 days to 43 days0CMO:0001243cerebrospinal fluid chloride level123mmol/l1.0MMO:0000451chloride ion-selective electrode method0.0controlled sodium content diet (8 %) (between 8 and 10 days)69691controlled sodium content diet (8 %) (between 8 and 10 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale50 days to 43 days0CMO:0000534absolute change in heart rate54beats/min6.0MMO:0000070intra-aortic abdominal radiotelemetry0.0sodium ion solution (800 mmol/l) (for 14 days)69698sodium ion solution (800 mmol/l) (for 14 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale50 days to 43 days0CMO:0000742percent change in heart rate10%1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0sodium ion solution (800 mmol/l) (for 14 days)69702sodium ion solution (800 mmol/l) (for 14 days)
335Poyan Mehr A, et al., Physiol Genomics 2003 Aug 15;14(3):209-16.urine albumin amountRS:0000817SS/Jrnot specified56 days12CMO:0000757urine albumin excretion rate69.96mg/dMMO:0000075enzyme linked immunosorbent assayurine0.0rat albumin ELISAcontrolled sodium content diet (0.2 %) 67824controlled sodium content diet (0.2 %)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000533absolute change in mean arterial blood pressure23mmHg1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69729sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0002035percent change in mean arterial blood pressure% change map17%1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69733sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000534absolute change in heart rate45beats/min3.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69737sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000742percent change in heart rate10%0.3MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then air-jet exposure (2 lb/in2) (for 0 hours)69741sodium ion solution (800 mmol/l) (for 4 days)air-jet exposure (2 lb/in2) (for 0 hours)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0002037maximum change in heart rate to change in mean arterial blood pressure ratioMaximum slope, bpm/mm Hg-1.8beats/min/mmHg0.2MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5~50 ug/min) then sodium nitroprusside (10~100 ug/min) 69745sodium ion solution (800 mmol/l) (for 4 days)phenylephrine (5~50 ug/min) sodium nitroprusside (10~100 ug/min)
344Huang BS, et al., Hypertension. 2007 Apr 9;.heart pumping traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0002036change in heart rate to change in mean arterial blood pressure ratioaverage slope, bpm/mm Hg-1.6beats/min/mmHg0.2MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days) then phenylephrine (5~50 ug/min) then sodium nitroprusside (10~100 ug/min) 69749sodium ion solution (800 mmol/l) (for 4 days)phenylephrine (5~50 ug/min) sodium nitroprusside (10~100 ug/min)
830Charron S, et al., Hypertension. 2005 Dec;46(6):1300-8. Epub 2005 Nov 14.arterial blood pressure traitRS:0000817SS/Jrmale59 days to 56 days16CMO:0000009mean arterial blood pressure177mmHgMMO:0000070intra-aortic abdominal radiotelemetry86400.0controlled sodium content diet (2 %) (for 21 days)68086controlled sodium content diet (2 %) (for 21 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left atrium diameterRS:0000817SS/Jrmale77 days40CMO:0001485heart left atrium end-systolic diameter4.99mm0.0870.55MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68299controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left atrium diameterRS:0000817SS/Jrmale77 days40CMO:0001486heart left atrium end-diastolic diameter3.43mm0.08220.52MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68307controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart pumping traitRS:0000817SS/Jrmale77 days40CMO:0001482heart isovolumetric relaxation timeisovolumetric relaxation time20.1ms0.40642.57MMO:0000199continuous wave doppler ultrasound0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68314controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left atrium diameterRS:0000817SS/Jrmale77 days40CMO:0001488heart left atrium fractional shortening(LADs - LADd)/ LADs x 100heart left atrium fractional shortening31.4%0.94555.98MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68322controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0001656receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio34.85%2.9410.1845MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then angiotensin II (0.3~300 umol/l) 69065Kreb's solution perfusateangiotensin II (0.3~300 umol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0001658logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50)-8.220.260.9007MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then angiotensin II (0.3~300 umol/l) 69067Kreb's solution perfusateangiotensin II (0.3~300 umol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.heart right ventricle DNA amountRS:0000817SS/Jrmale98 days11CMO:0001652heart right ventricle deoxyribonucleic acid content to body weight ratio1.1ug/g0.10.3317MMO:0000173spectrophotometry0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)69044controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 63 days)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0000716blood vessel contractile force measurement1.59g0.110.3811MMO:0000207tissue force analysis utilizing a force transducer0.0Kreb's solution perfusate then potassium chloride solution (40 mmol/l) 69048Kreb's solution perfusatepotassium chloride solution (40 mmol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.arterial blood pressure traitRS:0000817SS/Jrmale98 days to 68 days10CMO:0000009mean arterial blood pressure170mmHgMMO:0000015radiotelemetry0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)69025controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 63 days)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.blood vessel smooth muscle cell quantityRS:0000817SS/Jrmale98 days10CMO:0001646aorta smooth muscle cell count per unit vessel length/um - calculated aortic smooth muscle cell count90/um4.012.6491MMO:0000220ex vivo light microscopy with digital image analysis0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)69034controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 63 days)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.heart left ventricle DNA amountRS:0000817SS/Jrmale98 days11CMO:0001649heart left ventricle deoxyribonucleic acid content to body weight ratio5.8ug/g0.61.99MMO:0000173spectrophotometry0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 63 days)69039controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 63 days)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0000716blood vessel contractile force measurement1.39g0.060.2078MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then potassium chloride solution (40 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) 69050Kreb's solution perfusatepotassium chloride solution (40 mmol/l) NG-nitroarginine methyl ester (100 umol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0001656receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio104.06%4.716.2813MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then phenylephrine (1~100 mmol/l) 69052Kreb's solution perfusatephenylephrine (1~100 mmol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0000722logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)EC50 value is probably moles/liter-7.260.060.2078MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then phenylephrine (1~100 mmol/l) 69054Kreb's solution perfusatephenylephrine (1~100 mmol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0001656receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio141.72%7.7326.7775MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then phenylephrine (1~100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) 69056Kreb's solution perfusatephenylephrine (1~100 mmol/l) NG-nitroarginine methyl ester (100 umol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0000722logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)EC50 value is probably moles/liter-7.60.050.1732MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then phenylephrine (1~100 mmol/l) and NG-nitroarginine methyl ester (100 umol/l) 69058Kreb's solution perfusatephenylephrine (1~100 mmol/l) NG-nitroarginine methyl ester (100 umol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0001656receptor-dependent blood vessel maximum contractile force to receptor-independent blood vessel maximum contractile force ratio50.61%5.2918.3251MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then angiotensin II (0.3~300 umol/l) and NG-nitroarginine methyl ester (100 umol/l) 69069Kreb's solution perfusateangiotensin II (0.3~300 umol/l) NG-nitroarginine methyl ester (100 umol/l)
1096Dutil J, et al., Physiol Genomics 2005 Mar 1;.vasoconstriction traitRS:0000817SS/Jrmale98 days12CMO:0001658logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50)-7.920.361.2471MMO:0000207tissue force analysis utilizing a force transducer0.0isometric force transducerKreb's solution perfusate then angiotensin II (0.3~300 umol/l) then NG-nitroarginine methyl ester (100 umol/l) 69071Kreb's solution perfusateangiotensin II (0.3~300 umol/l) NG-nitroarginine methyl ester (100 umol/l)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale51 days to 43 days0CMO:0000533absolute change in mean arterial blood pressure1min measurement per 30min, 24 hr average17mmHg2.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 4 days)68138sodium ion solution (800 mmol/l) (for 4 days)
344Huang BS, et al., Hypertension. 2007 Apr 9;.arterial blood pressure traitRS:0000817SS/Jrmale61 days to 53 days0CMO:0000533absolute change in mean arterial blood pressure1min measurement per 30min, 24 hr average13mmHg1.0MMO:0000070intra-aortic abdominal radiotelemetry0.0blood pressure measured after infusionsodium ion solution (800 mmol/l) (for 14 days)68142sodium ion solution (800 mmol/l) (for 14 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.aorta blood flow traitRS:0000817SS/Jrmale77 days40CMO:0001481peak aortic velocitypeak aortic velocity110.5cm/s2.593116.4MMO:0000200pulsed wave doppler ultrasound0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68242controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
542Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943.heart left ventricle anterior wall thicknessRS:0000817SS/Jrmale77 days40CMO:0000986heart left ventricle anterior wall thickness0.186mm0.00320.02MMO:0000002transthoracic echocardiography0.0controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days)68250controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 35 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart left ventricle size traitRS:0000817SS/Jrnot specified0 days6CMO:0001192heart left ventricle end-systolic area0.25cm20.070.1715MMO:0000337echocardiography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 69602controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart left ventricle posterior wall thicknessRS:0000817SS/Jrnot specified0 days6CMO:0000239heart left ventricle posterior wall thickness2.9mm0.30.7348MMO:0000337echocardiography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 69604controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart left ventricle wall thicknessRS:0000817SS/Jrnot specified0 days6CMO:0000987heart ventricle septal wall thickness0.26cm0.020.049MMO:0000337echocardiography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 69606controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.life span traitRS:0000817SS/Jrnot specified0 days8CMO:0001193age at time of deathmedian108dMMO:0000344necropsy0.0visual observationcontrolled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 66 and 68 days)69608controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %) (between 66 and 68 days)
749Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4.heart left ventricle wall thicknessRS:0000817SS/Jrnot specified0 days6CMO:0000988heart left ventricle relative wall thickness107%34.083.2827MMO:0000337echocardiography0.0controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) 69611controlled sodium content diet (0.3 %) (between 10 and 12 days)controlled sodium content diet (2 %)
1663Chauvet C, et al., J Hypertens. 2011 Jul;29(7):1320-6. doi: 10.1097/HJH.0b013e32834705e4.arterial blood pressure traithas records that will be duplicated if entered need to add multiple refs once the functionality is inRS:0000817SS/Jrmale68 days16CMO:0000009mean arterial blood pressureaveraged over 12 daysserial mean184mmHg4.016.0MMO:0000015radiotelemetryabdominal aorta1036800.0telemetry probecontrolled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 12 days)96566controlled sodium content diet (0.2 %) (for 14 days)controlled sodium content diet (2 %) (for 12 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.heart pumping traitRS:0000817SS/Jrmale70 days to 68 days7CMO:0000002heart rateserial mean395beats/min6.2116.4301MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97978controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.heart pumping traitRS:0000817SS/Jrmale70 days to 68 days8CMO:0000002heart rateserial mean397beats/min9.0125.4841MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 28 days)97979controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 28 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.heart pumping traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000002heart rateserial mean394beats/min5.9714.6235MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 28 days)97980controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 28 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.heart pumping traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000002heart rateserial mean394beats/min5.9714.6235MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97981controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days8CMO:0000004systolic blood pressureserial mean201mmHg7.420.9304MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97983controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days8CMO:0000005diastolic blood pressureserial mean152mmHg6.4918.3565MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97987controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0001715tibia midshaft total cross-sectional area8.319mm20.08MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98011controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002710bone section structure model index2.520.103MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98111controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002711bone section connectivity density35.128/mm36.934MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98112controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002713bone section trabecular thickness0.071mm0.003MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98117controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002714bone section trabecular separation0.503mm0.069MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98119controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002706bone section mineralized tissue surface area5.296mm20.169MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98121controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002732tibia midshaft cortical thicknesscortical thickness0.544mm0.018MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98123controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.heart pumping traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000002heart rateserial mean394beats/min5.9714.6235MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)98193controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000009mean arterial blood pressureserial mean175mmHg3.759.1856MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)98194controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000292pulse pressureserial mean53.4mmHg1.94.654MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)98195controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000292pulse pressureserial mean53.4mmHg1.94.654MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)98196controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002708bone section surface densitymg HA/ccm1007.935mg/cm35.026MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98016controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002704bone section total volumetotal volume44.078mm30.974MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98017controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002705bone section mineralized tissue volumebone volume4.915mm30.879MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98019controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0002707bone section volume fractionBV/TVbone volume fraction - BV/TV0.1110.017MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98021controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days7CMO:0000005diastolic blood pressureserial mean154mmHg1.594.2067MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97986controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days7CMO:0000009mean arterial blood pressureserial mean174mmHg1.744.6036MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97989controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days8CMO:0000009mean arterial blood pressureserial mean175mmHg6.819.2333MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97990controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000009mean arterial blood pressureserial mean175mmHg3.759.1856MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97991controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days7CMO:0000292pulse pressureserial mean59.3mmHg0.551.4552MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97992controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days8CMO:0000292pulse pressureserial mean50.4mmHg2.356.6468MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97993controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000292pulse pressureserial mean53.4mmHg1.94.654MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97994controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.cancellous bone morphology traitRS:0000817SS/Jrmale70 days to 66 days0CMO:0001716tibia midshaft endosteal cross-sectional area3.023mm20.09MMO:0000570micro-computed tomography0.0controlled sodium content diet (2 %) (between 38 and 42 days)98013controlled sodium content diet (2 %) (between 38 and 42 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000004systolic blood pressureserial mean203mmHg4.1710.2144MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97984controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days7CMO:0000004systolic blood pressureserial mean213mmHg2.055.4238MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97982controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days20CMO:0000004systolic blood pressureserial mean195mmHg4.7221.1085MMO:0000054tail cuff volume pressure recording0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97985controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
1958Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25.arterial blood pressure traitRS:0000817SS/Jrmale70 days to 68 days6CMO:0000005diastolic blood pressureserial mean149mmHg3.558.6957MMO:0000015radiotelemetry0.0controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days)97988controlled sodium content diet (0.3 %) (for 12 days)controlled sodium content diet (2 %) (for 24 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days10CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean139mmHg2.78.5381MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 0 hours)102290controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 0 hours)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days11CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean139mmHg1.44.6433MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 0 hours)102291controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 0 hours)
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.heart massRS:0000817SS/Jrmale63 days10CMO:0000074heart weight to body weight ratio3.1g/kg0.060.1897MMO:0000005post excision weight measurement0.0controlled sodium content diet (8 %) (for 35 days)103241controlled sodium content diet (8 %) (for 35 days)
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.kidney massRS:0000817SS/Jrmale63 days15CMO:0000340both kidneys wet weight to body weight ratio6.39g/kg0.130.5035MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (for 35 days)103244controlled sodium content diet (0.3 %) (for 35 days)
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.kidney massRS:0000817SS/Jrmale63 days10CMO:0000340both kidneys wet weight to body weight ratio8.65g/kg0.170.5376MMO:0000005post excision weight measurement0.0controlled sodium content diet (8 %) (for 35 days)103245controlled sodium content diet (8 %) (for 35 days)
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.arterial blood pressure traitRS:0000817SS/Jrmale63 days15CMO:0000004systolic blood pressure159mmHg3.011.619MMO:0000014vascular transducer tipped catheter0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103248controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.arterial blood pressure traitRS:0000817SS/Jrmale63 days15CMO:0000004systolic blood pressure189mmHg6.023.2379MMO:0000014vascular transducer tipped catheter0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103249controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.arterial blood pressure traitRS:0000817SS/Jrmale63 days15CMO:0000009mean arterial blood pressure131mmHg3.011.619MMO:0000014vascular transducer tipped catheter0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103252controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.arterial blood pressure traitRS:0000817SS/Jrmale63 days10CMO:0000009mean arterial blood pressure153mmHg7.022.1359MMO:0000014vascular transducer tipped catheter0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103253controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.arterial blood pressure traitRS:0000817SS/Jrmale63 days15CMO:0000005diastolic blood pressure108mmHg3.011.619MMO:0000014vascular transducer tipped catheter0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103256controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.arterial blood pressure traitRS:0000817SS/Jrmale63 days10CMO:0000005diastolic blood pressure124mmHg6.018.9737MMO:0000014vascular transducer tipped catheter0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103257controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood triglyceride amountRS:0000817SS/Jrmale63 days15CMO:0000548plasma triglyceride level1.2mmol/l0.160.6197MMO:0000234plasma triglyceride analysis0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103260controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood triglyceride amountRS:0000817SS/Jrmale63 days10CMO:0000548plasma triglyceride level1.49mmol/l0.290.9171MMO:0000234plasma triglyceride analysis0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103261controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood cholesterol amountRS:0000817SS/Jrmale63 days15CMO:0000585plasma total cholesterol level79.1505mg/dl4.633217.9443MMO:0000284plasma total cholesterol measurement test0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103264controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood cholesterol amountRS:0000817SS/Jrmale63 days10CMO:0000585plasma total cholesterol level111.969mg/dl13.513542.7334MMO:0000284plasma total cholesterol measurement test0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103265controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.erythrocyte quantityRS:0000817SS/Jrmale63 days15CMO:0000037hematocrit48.8%0.51.9365MMO:0000214hematocrit analysis0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103268controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.erythrocyte quantityRS:0000817SS/Jrmale63 days10CMO:0000037hematocrit47%2.26.957MMO:0000214hematocrit analysis0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103269controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood hemoglobin amountRS:0000817SS/Jrmale63 days15CMO:0000506hemoglobin concentration4.94mmol/l0.040.1549MMO:0000295blood hemoglobin analysis0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103272controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood hemoglobin amountRS:0000817SS/Jrmale63 days10CMO:0000506hemoglobin concentration4.84mmol/l0.120.3795MMO:0000295blood hemoglobin analysis0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103273controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood sodium amountRS:0000817SS/Jrmale63 days15CMO:0001357red blood cell Na+/K+ ATPase activity3.5mmol/l0.050.1936MMO:0000441bioassay0.0controlled sodium content diet (0.3 %) (for 35 days) then anesthetic/analgesic103276controlled sodium content diet (0.3 %) (for 35 days)anesthetic/analgesic
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.blood sodium amountRS:0000817SS/Jrmale63 days10CMO:0001357red blood cell Na+/K+ ATPase activity3.77mmol/l0.040.1265MMO:0000441bioassay0.0controlled sodium content diet (8 %) (for 35 days) then anesthetic/analgesic103277controlled sodium content diet (8 %) (for 35 days)anesthetic/analgesic
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days10CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean140mmHg2.78.5381MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 3 days)102294controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 3 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days11CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean146mmHg2.16.9649MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 3 days)102295controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 3 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days10CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean152mmHg4.413.914MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 10 days)102298controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 10 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days11CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean160mmHg2.78.9549MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 10 days)102299controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 10 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days10CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean164mmHg4.915.4952MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 17 days)102302controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 17 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days11CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean179mmHg5.518.2414MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 17 days)102303controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 17 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days10CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean168mmHg5.316.7601MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 20 days)102306controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 20 days)
2661Mell B, et al., Physiol Genomics. 2015 Jun;47(6):187-97. doi: 10.1152/physiolgenomics.00136.2014. Epub 2015 Mar 31.arterial blood pressure traitRS:0000817SS/Jrmale0 days11CMO:0000004systolic blood pressuremean of 3 samples of undefined duration between 7am and 12pmserial mean180mmHg5.718.9048MMO:0000580intra-aortic abdominal radiotelemetry via femoral cannulation0.0controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days) and controlled meropenem content drinking water (50 mg/kg/d) (for 3 days) and controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days) then controlled cecal material content oral gavage (2 ml) (for 20 days)102307controlled vancomycin content drinking water (50 mg/kg/d) (for 3 days)controlled meropenem content drinking water (50 mg/kg/d) (for 3 days)controlled omeprazole content oral gavage (50 ml/kg/d) (for 3 days)controlled cecal material content oral gavage (2 ml) (for 20 days)
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.body massRS:0000817SS/Jrmale63 days15CMO:0000012body weight271g10.038.7298MMO:0000016body weighing method0.0controlled sodium content diet (0.3 %) (for 35 days)103236controlled sodium content diet (0.3 %) (for 35 days)
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.body massRS:0000817SS/Jrmale63 days10CMO:0000012body weight201g20.063.2456MMO:0000016body weighing method0.0controlled sodium content diet (8 %) (for 35 days)103237controlled sodium content diet (8 %) (for 35 days)
2802Vokurkov? M, et al., Hypertens Res. 2003 May;26(5):397-404.heart massRS:0000817SS/Jrmale63 days15CMO:0000074heart weight to body weight ratio2.59g/kg0.040.1549MMO:0000005post excision weight measurement0.0controlled sodium content diet (0.3 %) (for 35 days)103240controlled sodium content diet (0.3 %) (for 35 days)