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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord IDCondition 1aCondition 1bCondition 2Condition 3aCondition 3b
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood insulin amountRS:0000695Crl:SDmale77 days to 63 days9CMO:0000342plasma insulin levelF51mU/l7.021.0MMO:0000073radioimmunoassay0.0controlled fructose content diet (66 %) (between 14 and 28 days)75847controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood insulin amountRS:0000695Crl:SDmale77 days to 63 days8CMO:0000342plasma insulin levelC33mU/l2.05.6569MMO:0000073radioimmunoassay0.0control condition75848control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood insulin amountRS:0000695Crl:SDmale77 days to 63 days10CMO:0000342plasma insulin levelFT32mU/l4.012.6491MMO:0000073radioimmunoassay0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75849controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood insulin amountRS:0000695Crl:SDmale77 days to 63 days8CMO:0000342plasma insulin levelCT26mU/l2.05.6569MMO:0000073radioimmunoassay0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75850controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood insulin amountRS:0000695Crl:SDmale0 daysN/ACMO:0000342plasma insulin levelF53mU/l7.0MMO:0000073radioimmunoassay0.0controlled fructose content diet (66 %) (between 14 and 28 days)75879controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood insulin amountRS:0000695Crl:SDmale0 days8CMO:0000342plasma insulin levelFT68mU/l3.08.4853MMO:0000073radioimmunoassay0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75880controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002177food calorie intake ratefood energy intake28.9kcal/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (between 7 and 70 days)76105controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002177food calorie intake ratefood energy intake24.6kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)76106controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002177food calorie intake ratefood energy intake24.1kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)76107controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002177food calorie intake ratefood energy intake23.5kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)76108controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002177food calorie intake ratefood energy intake24.6kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)76109controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.visceral adipose massRS:0000695Crl:SDfemale105 days12CMO:0002183whole body visceral fat volumetotal body fat volume, cm313.9ml0.4331.5MMO:0000019magnetic resonance imaging0.0controlled ethanol content drinking water (1 %) (for 70 days)75822controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.visceral adipose massRS:0000695Crl:SDfemale105 days12CMO:0002183whole body visceral fat volumetotal body fat volume, cm314.3ml0.8663.0MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75823controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.visceral adipose massRS:0000695Crl:SDfemale105 days12CMO:0002183whole body visceral fat volumetotal body fat volume, cm313.9ml0.69282.4MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75824controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.visceral adipose massRS:0000695Crl:SDfemale105 days12CMO:0002183whole body visceral fat volumetotal body fat volume, cm313.8ml0.75062.6MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75825controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.visceral adipose massRS:0000695Crl:SDfemale105 days12CMO:0002183whole body visceral fat volumetotal body fat volume, cm315.3ml0.80832.8MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75826controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.subcutaneous adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002182whole body subcutaneous fat volumetotal body fat volume, cm314.4ml0.57742.0MMO:0000019magnetic resonance imaging0.0controlled ethanol content drinking water (1 %) (for 70 days)75817controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.subcutaneous adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002182whole body subcutaneous fat volumetotal body fat volume, cm315.4ml0.80832.8MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75818controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.subcutaneous adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002182whole body subcutaneous fat volumetotal body fat volume, cm315.6ml0.75062.6MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75819controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.subcutaneous adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002182whole body subcutaneous fat volumetotal body fat volume, cm315.1ml0.83722.9MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75820controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.subcutaneous adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002182whole body subcutaneous fat volumetotal body fat volume, cm316.4ml0.6642.3MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75821controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days12CMO:0002198fructose drink intake rateweek one32g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75726controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002198fructose drink intake rateweek one28.3g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)75730controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale42 days12CMO:0002198fructose drink intake rateweek one20.8g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled ethanol content drinking water (1 %) (for 7 days)75722controlled fructose content drinking water (5 %) (for 7 days)controlled ethanol content drinking water (1 %) (for 7 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale77 days to 63 days10CMO:0002431metformin drink intake ratemetformin drink intake rate35ml/d0.41.2649MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75865controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale77 days to 63 days8CMO:0002431metformin drink intake ratemetformin drink intake rate37ml/d0.51.4142MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75866controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale42 days10CMO:0002431metformin drink intake ratemetformin drink intake rate33ml/d0.61.8974MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) 75869controlled metformin content drinking water (350-500 mg/kg/d) controlled fructose content diet (66 %)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale42 days8CMO:0002431metformin drink intake ratemetformin drink intake rate31ml/d0.30.8485MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) 75870controlled metformin content drinking water (350-500 mg/kg/d)
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.body massRS:0000695Crl:SDmale95 days to 89 days11CMO:0001400maximum body weight loss to initial body weight ratio3.3%0.61.99MMO:0000016body weighing method0.0arterial catheter implantation1daysarterial catheter implantation (for 1 days)107186arterial catheter implantation (for 1 days)
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.blood campesterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001944plasma campesterol level1.3mg/dlMMO:0000160unspecified method0.0plasma campesterol measurement testcontrol condition70515control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.blood sitosterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001943plasma sitosterol level1.95mg/dlMMO:0000160unspecified method0.0control condition70532control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucagon amountRS:0000695Crl:SDmale0 days8CMO:0001296plasma glucagon levelFT353pmol/l27.076.3675MMO:0000073radioimmunoassay0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75923controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucagon amountRS:0000695Crl:SDmale0 days8CMO:0001296plasma glucagon levelFT402pmol/l32.090.5097MMO:0000073radioimmunoassay0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75924controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002181total body fat volumetotal body fat volume, cm328.2cm30.98153.4MMO:0000019magnetic resonance imaging0.0controlled ethanol content drinking water (1 %) (for 70 days)75812controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002181total body fat volumetotal body fat volume, cm329.8cm31.64545.7MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75813controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002181total body fat volumetotal body fat volume, cm329.6cm31.41454.9MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75814controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002181total body fat volumetotal body fat volume, cm328.9cm31.50115.2MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75815controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002181total body fat volumetotal body fat volume, cm331.7cm31.44345.0MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75816controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body lean massRS:0000695Crl:SDfemale105 days12CMO:0002186whole body lean tissue volumewhole body lean tissue volume cm395.5cm30.83722.9MMO:0000019magnetic resonance imaging0.0controlled ethanol content drinking water (1 %) (for 70 days)75827controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body lean massRS:0000695Crl:SDfemale105 days12CMO:0002186whole body lean tissue volumewhole body lean tissue volume cm395.2cm31.24134.3MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75828controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body lean massRS:0000695Crl:SDfemale105 days12CMO:0002186whole body lean tissue volumewhole body lean tissue volume cm396.6cm31.44345.0MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75829controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body lean massRS:0000695Crl:SDfemale105 days12CMO:0002186whole body lean tissue volumewhole body lean tissue volume cm395.4cm31.73216.0MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75830controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body lean massRS:0000695Crl:SDfemale105 days12CMO:0002186whole body lean tissue volumewhole body lean tissue volume cm396.1cm31.87646.5MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75831controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood creatinine amountplasma creatinineRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000537plasma creatinine level0.166628706mg/dl0.021MMO:0000354automated plasma creatinine analysiscontrol condition106867control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood creatinine amountplasma creatinineRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000537plasma creatinine level0.198868476mg/dl0.0MMO:0000354automated plasma creatinine analysiscontrol condition106868control condition
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood aspartate transaminase amountRS:0000695Crl:SDmale63 days5CMO:0000581serum aspartate aminotransferase activity level61.8U/l1.31932.95MMO:0000554automated serum analysis0.0control condition (for 63 days)105049control condition (for 63 days)
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood alkaline phosphatase amountRS:0000695Crl:SDmale63 days5CMO:0000577serum alkaline phosphatase activity level294.2U/l28.420463.55MMO:0000554automated serum analysis0.0control condition (for 63 days)105053control condition (for 63 days)
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.arterial blood pressure traitInitial MAPRS:0000695Crl:SDmale95 days to 89 days11CMO:0000009mean arterial blood pressure115mmHg3.09.9499MMO:0000013vascular fluid filled catheter300.05-second intervalsarterial catheter implantation (for 1 days)107340arterial catheter implantation (for 1 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days to 35 days12CMO:0000420body weight gainweek one80.1g2.59819.0MMO:0000016body weighing method0.0controlled ethanol content drinking water (1 %) (for 70 days)75757controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days to 35 days12CMO:0000420body weight gainweek one82.6g2.56928.9MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75760controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days to 35 days12CMO:0000420body weight gainweek one86.4g4.012613.9MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75761controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days to 35 days12CMO:0000420body weight gainweek one86.2g4.156914.4MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75758controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days to 35 days12CMO:0000420body weight gainweek one88.3g2.22287.7MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75759controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood urea nitrogen amountRS:0000695Crl:SDmale63 days5CMO:0000587serum urea nitrogen level12.4mg/dl0.2460.55MMO:0000554automated serum analysis0.0control condition (for 63 days)105059control condition (for 63 days)
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.kidney massRS:0000695Crl:SDmale63 days5CMO:0000340both kidneys wet weight to body weight ratio0.097g/kg0.00130.003MMO:0000005post excision weight measurement0.0control condition (for 63 days)105047control condition (for 63 days)
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.erythrocyte quantityinitial hematocrit, final hematocrit, change in hematocritRS:0000695Crl:SDmale95 days to 89 days11CMO:0000037hematocrit40.9%0.92.985MMO:0000215microhematocrit tube assay with visual assessment0.0arterial catheter implantation (for 1 days)107244arterial catheter implantation (for 1 days)
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.erythrocyte quantityinitial hematocrit, final hematocrit, change in hematocritRS:0000695Crl:SDmale95 days to 89 days11CMO:0000037hematocrit29.8%1.85.9699MMO:0000215microhematocrit tube assay with visual assessment0.0arterial catheter implantation (for 1 days) then controlled hemorrhage (between 1 and 6 hours)107260arterial catheter implantation (for 1 days)controlled hemorrhage (between 1 and 6 hours)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood chloride amountplasma chlorideRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000059plasma chloride level101.83mmol/l0.31MMO:0000821automated plasma chloride testcontrol condition106871control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood chloride amountplasma chlorideRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000059plasma chloride level101.6mmol/l0.67MMO:0000821automated plasma chloride testcontrol condition106872control condition
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood bilirubin amountRS:0000695Crl:SDmale63 days5CMO:0000376serum total bilirubin levelbelow lower limit0.1mg/dl0.00.0MMO:0000554automated serum analysis0.0control condition (for 63 days)105055control condition (for 63 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood glucose amountRS:0000695Crl:SDfemale98 days12CMO:0000046blood glucose levelweek one81mg/dl2.33838.1MMO:0000112blood glucose analysis0.0controlled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 63 days)75793controlled fructose content drinking water (5 %) (for 63 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 63 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood glucose amountRS:0000695Crl:SDfemale98 days12CMO:0000046blood glucose levelweek one79.2mg/dl1.87066.48MMO:0000112blood glucose analysis0.0controlled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 63 days)75794controlled fructose content drinking water (5 %) (for 63 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 63 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood glucose amountRS:0000695Crl:SDfemale98 days12CMO:0000046blood glucose levelweek one82.8mg/dl4.10514.22MMO:0000112blood glucose analysis0.0controlled ethanol content drinking water (1 %) (for 63 days)75791controlled ethanol content drinking water (1 %) (for 63 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood glucose amountRS:0000695Crl:SDfemale98 days12CMO:0000046blood glucose levelweek one81mg/dl2.7549.54MMO:0000112blood glucose analysis0.0controlled fructose content drinking water (5 %) (for 63 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 63 days)75795controlled fructose content drinking water (5 %) (for 63 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 63 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood glucose amountRS:0000695Crl:SDfemale98 days12CMO:0000046blood glucose levelweek one84.6mg/dl3.637312.6MMO:0000112blood glucose analysis0.0controlled fructose content drinking water (5 %) (for 63 days) and controlled ethanol content drinking water (1 %) (for 63 days)75792controlled fructose content drinking water (5 %) (for 63 days)controlled ethanol content drinking water (1 %) (for 63 days)
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood cholesterol amountRS:0000695Crl:SDmale63 days5CMO:0000363serum total cholesterol level89.4mg/dl3.32737.44MMO:0000554automated serum analysis0.0control condition (for 63 days)105063control condition (for 63 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.arterial blood pressure traitRS:0000695Crl:SDmale77 days to 63 days9CMO:0000004systolic blood pressureF159mmHg2.06.0MMO:0000031tail cuff plethysmographytail0.0controlled fructose content diet (66 %) (between 14 and 28 days)75851controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.arterial blood pressure traitRS:0000695Crl:SDmale77 days to 63 days8CMO:0000004systolic blood pressureC141mmHg2.05.6569MMO:0000031tail cuff plethysmographytail0.0control condition75852control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.arterial blood pressure traitRS:0000695Crl:SDmale77 days to 63 days10CMO:0000004systolic blood pressureFT143mmHg2.06.3246MMO:0000031tail cuff plethysmographytail0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75853controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.arterial blood pressure traitRS:0000695Crl:SDmale77 days to 63 days8CMO:0000004systolic blood pressureCT142mmHg3.08.4853MMO:0000031tail cuff plethysmographytail0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75854controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.arterial blood pressure traitRS:0000695Crl:SDmale0 daysN/ACMO:0000004systolic blood pressureF160mmHg3.0MMO:0000031tail cuff plethysmographytail0.0controlled fructose content diet (66 %) (between 14 and 28 days)75925controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.arterial blood pressure traitRS:0000695Crl:SDmale0 days8CMO:0000004systolic blood pressureFT158mmHg3.08.4853MMO:0000031tail cuff plethysmographytail0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75926controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
3126Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6.arterial blood pressure traitRS:0000695Crl:SDmale660 days to 540 days9CMO:0000004systolic blood pressure168mmHg6.018.0MMO:0000031tail cuff plethysmographytail0.0controlled protein content diet (20 %) then water (for 120 days)108593controlled protein content diet (20 %) water (for 120 days)
3126Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6.arterial blood pressure traitRS:0000695Crl:SDmale660 days to 540 days8CMO:0000004systolic blood pressure130mmHg7.019.799MMO:0000031tail cuff plethysmographytail0.0controlled protein content diet (20 %) then perindopril (1 mg/kg/d) (for 120 days)108594controlled protein content diet (20 %) perindopril (1 mg/kg/d) (for 120 days)
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.blood cholesterol amountRS:0000695Crl:SDnot specified77 days2CMO:0000585plasma total cholesterol level54.6mg/dlMMO:0000160unspecified method0.0control condition70158control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood sodium amountplasma sodiumRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000060plasma sodium level139.6mmol/l0.42MMO:0000823automated plasma sodium testcontrol condition106851control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood sodium amountplasma sodiumRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000060plasma sodium level141.8mmol/l0.58MMO:0000823automated plasma sodium testcontrol condition106852control condition
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood alanine transaminase amountRS:0000695Crl:SDmale63 days5CMO:0000575serum alanine aminotransferase activity level54.8U/l0.97052.17MMO:0000554automated serum analysis0.0control condition (for 63 days)105051control condition (for 63 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale77 days to 63 days9CMO:0000741water drink intake rateF39ml/d0.72.1MMO:0000160unspecified method0.0controlled fructose content diet (66 %) (between 14 and 28 days)75863controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale77 days to 63 days8CMO:0000741water drink intake rateC43ml/d1.74.8083MMO:0000160unspecified method0.0control condition75864control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale42 days9CMO:0000741water drink intake rateF34ml/d0.30.9MMO:0000160unspecified method0.0controlled fructose content diet (66 %) 75867controlled fructose content diet (66 %)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.drinking behavior traitRS:0000695Crl:SDmale42 days8CMO:0000741water drink intake rateC35ml/d0.71.9799MMO:0000160unspecified method0.0control condition75868control condition
3126Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6.total urine protein amountRS:0000695Crl:SDmale540 days to 420 days9CMO:0000756urine total protein excretion rate54mg/d5.015.0MMO:0000426Bradford protein assay0.0controlled protein content diet (20 %) 108595controlled protein content diet (20 %)
3126Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6.total urine protein amountRS:0000695Crl:SDmale660 days to 540 days9CMO:0000756urine total protein excretion rate57mg/d5.015.0MMO:0000426Bradford protein assay0.0controlled protein content diet (20 %) then water (for 120 days)108596controlled protein content diet (20 %) water (for 120 days)
3126Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6.total urine protein amountRS:0000695Crl:SDmale660 days to 540 days8CMO:0000756urine total protein excretion rate32mg/d9.025.4558MMO:0000426Bradford protein assay0.0controlled protein content diet (20 %) then perindopril (1 mg/kg/d) (for 120 days)108597controlled protein content diet (20 %) perindopril (1 mg/kg/d) (for 120 days)
3126Zoja C, etal., Am J Med. 1992 Apr 27;92(4B):60S-63S. doi: 10.1016/0002-9343(92)90149-6.total urine protein amountRS:0000695Crl:SDmale540 days to 420 days8CMO:0000756urine total protein excretion rate61mg/d11.031.1127MMO:0000426Bradford protein assay0.0controlled protein content diet (20 %) 108598controlled protein content diet (20 %)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale77 days to 63 days9CMO:0000042plasma glucose levelF117mg/dl3.610.8MMO:0000329liquid phase colorimetry0.0controlled fructose content diet (66 %) (between 14 and 28 days)75855controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale77 days to 63 days8CMO:0000042plasma glucose levelC111.6mg/dl1.85.0912MMO:0000329liquid phase colorimetry0.0control condition75856control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale77 days to 63 days10CMO:0000042plasma glucose levelFT111.6mg/dl1.85.6921MMO:0000329liquid phase colorimetry0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75857controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale77 days to 63 days8CMO:0000042plasma glucose levelCT111.6mg/dl5.415.2735MMO:0000329liquid phase colorimetry0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75858controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale42 days9CMO:0000042plasma glucose levelF108mg/dl1.85.4MMO:0000329liquid phase colorimetry0.0controlled fructose content diet (66 %) 75859controlled fructose content diet (66 %)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale42 days8CMO:0000042plasma glucose levelC118.8mg/dl5.415.2735MMO:0000329liquid phase colorimetry0.0control condition75860control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale42 days10CMO:0000042plasma glucose levelFT104.4mg/dl9.028.4605MMO:0000329liquid phase colorimetry0.0controlled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) 75861controlled metformin content drinking water (350-500 mg/kg/d) controlled fructose content diet (66 %)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale42 days8CMO:0000042plasma glucose levelCT106.2mg/dl9.025.4558MMO:0000329liquid phase colorimetry0.0controlled metformin content drinking water (350-500 mg/kg/d) 75862controlled metformin content drinking water (350-500 mg/kg/d)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale0 days8CMO:0000042plasma glucose levelFT102.6mg/dl3.610.1823MMO:0000329liquid phase colorimetry0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75921controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.blood glucose amountRS:0000695Crl:SDmale0 days8CMO:0000042plasma glucose levelFT82.8mg/dl7.220.3647MMO:0000329liquid phase colorimetry0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) then insulin (2 U/kg/d) (for 14 days)75922controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)insulin (2 U/kg/d) (for 14 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood glucose amountplasma glucoseRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000042plasma glucose level180mg/dl7.56MMO:0000735automated plasma glucose analysiscontrol condition106859control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood glucose amountplasma glucoseRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000042plasma glucose level160.02mg/dl4.32MMO:0000735automated plasma glucose analysiscontrol condition106860control condition
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood glucose amountRS:0000695Crl:SDmale63 days5CMO:0000543serum glucose level132.6mg/dl2.52235.64MMO:0000554automated serum analysis0.0control condition (for 63 days)105065control condition (for 63 days)
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.blood creatinine amountRS:0000695Crl:SDmale63 days5CMO:0000057serum creatinine level0.23mg/dl0.00450.01MMO:0000554automated serum analysis0.0control condition (for 63 days)105061control condition (for 63 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood urea nitrogen amountplasma urea nitrogenRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000586plasma urea nitrogen level6.01mmol/l0.56MMO:0000818automated plasma urea analysiscontrol condition106839control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood urea nitrogen amountplasma urea nitrogenRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000586plasma urea nitrogen level5.21mmol/l0.43MMO:0000818automated plasma urea analysiscontrol condition106840control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood triglyceride amountRS:0000695Crl:SDfemale105 days12CMO:0000548plasma triglyceride levelweek one1.7mmol/l0.1790.62MMO:0000234plasma triglyceride analysis0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75788controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood triglyceride amountRS:0000695Crl:SDfemale105 days12CMO:0000548plasma triglyceride levelweek one1.3mmol/l0.10390.36MMO:0000234plasma triglyceride analysis0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75787controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood triglyceride amountRS:0000695Crl:SDfemale105 days11CMO:0000548plasma triglyceride levelweek one1.7mmol/l0.23820.79MMO:0000234plasma triglyceride analysis0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75789controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood triglyceride amountRS:0000695Crl:SDfemale105 days12CMO:0000548plasma triglyceride levelweek one1.6mmol/l0.23960.83MMO:0000234plasma triglyceride analysis0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75790controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood triglyceride amountRS:0000695Crl:SDfemale105 days12CMO:0000548plasma triglyceride levelweek one0.88mmol/l0.06350.22MMO:0000234plasma triglyceride analysis0.0controlled ethanol content drinking water (1 %) (for 70 days)75786controlled ethanol content drinking water (1 %) (for 70 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood triglyceride amountplasma triglycerideRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000548plasma triglyceride level0.83mmol/l0.22MMO:0000734automated plasma triglyceride analysiscontrol condition106843control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood triglyceride amountplasma triglycerideRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000548plasma triglyceride level0.77mmol/l0.09MMO:0000734automated plasma triglyceride analysiscontrol condition106844control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000092liver weightweek one, liver weight4.8g0.08370.29MMO:0000005post excision weight measurement0.0controlled ethanol content drinking water (1 %) (for 70 days)75771controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000092liver weightliver weight5.1g0.05770.2MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75772controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000092liver weightliver weight5.6g0.19630.68MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75774controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000092liver weightliver weight5.4g0.12410.43MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75775controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000092liver weightliver weight5.6g0.24830.86MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75773controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood potassium amountplasma potassiumRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000061plasma potassium level4.33mmol/l0.15MMO:0000822automated plasma potassium testcontrol condition106855control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood potassium amountplasma potassiumRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000061plasma potassium level3.74mmol/l0.08MMO:0000822automated plasma potassium testcontrol condition106856control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood albumin amountplasma albumin levelRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000056plasma albumin level25.8g/l0.4MMO:0000351automated plasma albumin analysiscontrol condition106831control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood albumin amountplasma albumin levelRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000056plasma albumin level28.2g/l1.3MMO:0000351automated plasma albumin analysiscontrol condition106832control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale42 days12CMO:0000427food intake rateweek one9.6g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)75720controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days12CMO:0000427food intake rateweek one8.3g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75734controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale42 days12CMO:0000427food intake rateweek one10.8g/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (for 7 days)75717controlled ethanol content drinking water (1 %) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale42 days12CMO:0000427food intake rateweek one10g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)75719controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0000427food intake rateweek one8.7g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)75741controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0000427food intake rateweek one10.2g/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (between 7 and 70 days)75737controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days12CMO:0000427food intake rateweek one7.9g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75735controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0000427food intake rateweek one8.7g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)75738controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0000427food intake rateweek one8.5g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)75739controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale42 days12CMO:0000427food intake rateweek one10.1g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled ethanol content drinking water (1 %) (for 7 days)75718controlled fructose content drinking water (5 %) (for 7 days)controlled ethanol content drinking water (1 %) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days12CMO:0000427food intake rateweek one10g/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (for 70 days)75733controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days12CMO:0000427food intake rateweek one7.8g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75736controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days12CMO:0000427food intake rateweek one8.3g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75743controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0000427food intake rateweek one8.3g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)75740controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.eating behavior traitRS:0000695Crl:SDfemale42 days12CMO:0000427food intake rateweek one9.3g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)75742controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale77 days to 63 days9CMO:0000427food intake rateF26g/d1.75.1MMO:0000160unspecified method0.0controlled fructose content diet (66 %) (between 14 and 28 days)75871controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale77 days to 63 days8CMO:0000427food intake rateC28g/d0.92.5456MMO:0000160unspecified method0.0control condition75872control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale77 days to 63 days10CMO:0000427food intake rateFT24g/d0.41.2649MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days)75873controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)controlled fructose content diet (66 %) (between 14 and 28 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale77 days to 63 days8CMO:0000427food intake rateCT24g/d0.10.2828MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)75874controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale42 days9CMO:0000427food intake rateF19g/d0.30.9MMO:0000160unspecified method0.0controlled fructose content diet (66 %) 75875controlled fructose content diet (66 %)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale42 days8CMO:0000427food intake rateC18g/d0.30.8485MMO:0000160unspecified method0.0control condition75876control condition
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale42 days10CMO:0000427food intake rateFT18g/d0.30.9487MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) 75877controlled metformin content drinking water (350-500 mg/kg/d) controlled fructose content diet (66 %)
1540Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7.eating behavior traitRS:0000695Crl:SDmale42 days8CMO:0000427food intake rateCT17g/d0.20.5657MMO:0000160unspecified method0.0controlled metformin content drinking water (350-500 mg/kg/d) 75878controlled metformin content drinking water (350-500 mg/kg/d)
3010Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011.liver massRS:0000695Crl:SDmale63 days5CMO:0000633liver weight to body weight ratio0.46g/kg0.01340.03MMO:0000005post excision weight measurement0.0control condition (for 63 days)105045control condition (for 63 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one175.1g2.36718.2MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75756controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale35 days12CMO:0000012body weightweek one87.8g3.92613.6MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) and controlled ethanol content drinking water (1 %) 75748controlled fructose content drinking water (5 %) controlled ethanol content drinking water (1 %)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale35 days12CMO:0000012body weightweek one88.7g2.973410.3MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) and controlled bisphenol A content drinking water (0.25 mg/l) 75750controlled fructose content drinking water (5 %) controlled bisphenol A content drinking water (0.25 mg/l)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale35 days12CMO:0000012body weightweek one88.3g3.377511.7MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) and controlled bisphenol A content drinking water (2.5 mg/l) 75751controlled fructose content drinking water (5 %) controlled bisphenol A content drinking water (2.5 mg/l)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one171.7g2.07857.2MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75753controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one172.9g3.406411.8MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75755controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale35 days12CMO:0000012body weightweek one92.6g3.031110.5MMO:0000016body weighing method0.0controlled ethanol content drinking water (1 %) 75747controlled ethanol content drinking water (1 %)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days11CMO:0000012body weightweek one172.3g1.62825.4MMO:0000016body weighing method0.0controlled ethanol content drinking water (1 %) (for 70 days)75752controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one173.7g2.85799.9MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75754controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale35 days12CMO:0000012body weightweek one84.7g3.204311.1MMO:0000016body weighing method0.0controlled fructose content drinking water (5 %) and controlled bisphenol A content drinking water (0.025 mg/l) 75749controlled fructose content drinking water (5 %) controlled bisphenol A content drinking water (0.025 mg/l)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one148.4g1.35684.7MMO:0000019magnetic resonance imaging0.0controlled ethanol content drinking water (1 %) (for 70 days)75796controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one149.1g1.70325.9MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75797controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one151.5g2.65589.2MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75798controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one149.6g2.74249.5MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75799controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.body massRS:0000695Crl:SDfemale105 days12CMO:0000012body weightweek one153.1g2.30948.0MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75800controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.body massRS:0000695Crl:SDmale94 days to 88 days11CMO:0000012body weight448g8.026.533MMO:0000016body weighing method0.0control condition107351control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale42 days12CMO:0001407ethanol drink intake rateweek one11.6g/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (for 7 days)75721controlled ethanol content drinking water (1 %) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0001407ethanol drink intake rateweek one11.5g/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) 75729controlled ethanol content drinking water (1 %)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days12CMO:0001407ethanol drink intake rateweek one10.8g/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (for 70 days)75725controlled ethanol content drinking water (1 %) (for 70 days)
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.liver cholesterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001597liver cholesterol level1.72mg/gMMO:0000160unspecified method0.0tissue total cholesterol analysiscontrol condition70163control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002197left renal fat pad weight to body weight ratiototal body fat volume, cm30.43%0.02310.08MMO:0000005post excision weight measurement0.0controlled ethanol content drinking water (1 %) (for 70 days)75842controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days11CMO:0002197left renal fat pad weight to body weight ratiototal body fat volume, cm30.5%0.03320.11MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75843controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002197left renal fat pad weight to body weight ratiototal body fat volume, cm30.44%0.02020.07MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75844controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002197left renal fat pad weight to body weight ratiototal body fat volume, cm30.44%0.02310.08MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75845controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002197left renal fat pad weight to body weight ratiototal body fat volume, cm30.5%0.03750.13MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75846controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.blood phytosterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001945plasma phytosterol level3.3mg/dlMMO:0000160unspecified method0.0control condition70545control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002190liver fat volume to total liver volume ratiototal body fat volume, cm35.5%0.28871.0MMO:0000019magnetic resonance imaging0.0controlled ethanol content drinking water (1 %) (for 70 days)75832controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver adipose amountRS:0000695Crl:SDfemale105 days11CMO:0002190liver fat volume to total liver volume ratiototal body fat volume, cm35.6%0.25930.86MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75833controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002190liver fat volume to total liver volume ratiototal body fat volume, cm36.4%0.34641.2MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75834controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002190liver fat volume to total liver volume ratiototal body fat volume, cm37%0.49071.7MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75835controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver adipose amountRS:0000695Crl:SDfemale105 days12CMO:0002190liver fat volume to total liver volume ratiototal body fat volume, cm36.9%0.21070.73MMO:0000019magnetic resonance imaging0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75836controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002195left renal fat pad weighttotal body fat volume, cm30.74g0.04330.15MMO:0000005post excision weight measurement0.0controlled ethanol content drinking water (1 %) (for 70 days)75837controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002195left renal fat pad weighttotal body fat volume, cm30.86g0.06060.21MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75838controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002195left renal fat pad weighttotal body fat volume, cm30.77g0.04040.14MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75839controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002195left renal fat pad weighttotal body fat volume, cm30.76g0.04040.14MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75840controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.renal fat pad massRS:0000695Crl:SDfemale105 days12CMO:0002195left renal fat pad weighttotal body fat volume, cm30.88g0.07220.25MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75841controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002251fructose drink calorie intake rate0kcal/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (between 7 and 70 days)76100controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002251fructose drink calorie intake ratefructose energy intake5.7kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days)76101controlled fructose content drinking water (5 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002251fructose drink calorie intake ratefructose energy intake5.6kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)76102controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002251fructose drink calorie intake ratefructose energy intake6kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)76103controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002251fructose drink calorie intake ratefructose energy intake4.9kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)76104controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.consumption behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002253total calorie intake ratetotal energy intake28.9kcal/dMMO:0000160unspecified method0.0controlled ethanol content drinking water (1 %) (between 7 and 70 days)76110controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.consumption behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002253total calorie intake ratetotal energy intake30.3kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days)76111controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled ethanol content drinking water (1 %) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.consumption behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002253total calorie intake ratetotal energy intake29.7kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)76112controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.consumption behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002253total calorie intake ratetotal energy intake29.5kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)76113controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.consumption behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002253total calorie intake ratetotal energy intake29.5kcal/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)76114controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood alanine transaminase amountplasma ALTRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000044plasma alanine aminotransferase activity level51.16U/l5.41MMO:0000808automated plasma alanine aminotransferase activity assayautomated plasma alanine aminotransferase activity assay (MMO:0000808)control condition106879control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood alanine transaminase amountplasma ALTRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000044plasma alanine aminotransferase activity level41U/l4.32MMO:0000808automated plasma alanine aminotransferase activity assayautomated plasma alanine aminotransferase activity assay (MMO:0000808)control condition106880control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.brain cholesterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001935brain cholesterol level10.95mg/gMMO:0000160unspecified method0.0tissue lipid analysiscontrol condition70524control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.brain phytosterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001936brain phytosterol level0.03mg/gMMO:0000160unspecified method0.0tissue lipid analysiscontrol condition70554control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.brain campesterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001937brain campesterol level0.02mg/gMMO:0000160unspecified method0.0tissue campesterol measurement testcontrol condition70528control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.brain sitosterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001938brain sitosterol level0.02mg/gMMO:0000160unspecified method0.0tissue lipid analysiscontrol condition70541control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.liver sitosterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001940liver sitosterol level0.03mg/gMMO:0000160unspecified method0.0tissue lipid analysiscontrol condition70537control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.liver campesterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001941liver campesterol level0.03mg/gMMO:0000160unspecified method0.0tissue campesterol measurement testcontrol condition70520control condition
1300Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4.liver phytosterol amountRS:0000695Crl:SDnot specified77 days2CMO:0001942liver phytosterol level0.05mg/gMMO:0000160unspecified method0.0tissue lipid analysiscontrol condition70550control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale42 days12CMO:0002199bisphenol A in fructose drink intake rateweek one21.8g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)75724controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale42 days12CMO:0002199bisphenol A in fructose drink intake rateweek one20.4g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)75723controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days12CMO:0002199bisphenol A in fructose drink intake rateweek one36.8g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75728controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002199bisphenol A in fructose drink intake rateweek one28.1g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)75731controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days12CMO:0002199bisphenol A in fructose drink intake rateweek one29.4g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75745controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002199bisphenol A in fructose drink intake rateweek one24.7g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)75746controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days to 42 days12CMO:0002199bisphenol A in fructose drink intake rateweek one30.1g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)75732controlled fructose content drinking water (5 %) (between 7 and 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale42 days12CMO:0002199bisphenol A in fructose drink intake rateweek one19.8g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)75744controlled fructose content drinking water (5 %) (for 7 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.drinking behavior traitRS:0000695Crl:SDfemale105 days12CMO:0002199bisphenol A in fructose drink intake rateweek one33g/dMMO:0000160unspecified method0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75727controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.eating behavior traitFood consumed (g) postsurgery per 100 g BWRS:0000695Crl:SDmale95 days to 89 days11CMO:0002214food intake weight to body weight ratio5.5g/d/100g0.30.995MMO:0000620food intake measuring method0.0arterial catheter implantation1daysarterial catheter implantation (for 1 days)107149arterial catheter implantation (for 1 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood cholesterol amountRS:0000695Crl:SDfemale105 days12CMO:0000585plasma total cholesterol levelweek one115.83mg/dl1.89486.5637MMO:0000284plasma total cholesterol measurement test0.0controlled ethanol content drinking water (1 %) (for 70 days)75781controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood cholesterol amountRS:0000695Crl:SDfemale105 days12CMO:0000585plasma total cholesterol levelweek one119.691mg/dl2.56358.8803MMO:0000284plasma total cholesterol measurement test0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75782controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood cholesterol amountRS:0000695Crl:SDfemale105 days12CMO:0000585plasma total cholesterol levelweek one123.552mg/dl1.78336.1776MMO:0000284plasma total cholesterol measurement test0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75783controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood cholesterol amountRS:0000695Crl:SDfemale105 days11CMO:0000585plasma total cholesterol levelweek one119.691mg/dl2.32837.722MMO:0000284plasma total cholesterol measurement test0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75784controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.blood cholesterol amountRS:0000695Crl:SDfemale105 days12CMO:0000585plasma total cholesterol levelweek one127.413mg/dl2.22917.722MMO:0000284plasma total cholesterol measurement test0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75785controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood cholesterol amountplasma total cholesterolRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000585plasma total cholesterol level66.7953mg/dl8.4942MMO:0000691automated plasma total cholesterol analysiscontrol condition106847control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood cholesterol amountplasma total cholesterolRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000585plasma total cholesterol level71.0424mg/dl6.1776MMO:0000691automated plasma total cholesterol analysiscontrol condition106848control condition
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale364 days6CMO:0002247kidney glomerulus volume3.14x 10E6 um30.190.4654MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz308daysstreptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)100772streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale364 days6CMO:0002247kidney glomerulus volume2.18x 10E6 um30.110.2694MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz308daysstreptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)100773streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale364 days6CMO:0002247kidney glomerulus volume2.06x 10E6 um30.140.3429MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz308daysstreptozotocin (60 mg/kg/d) then insulin (for 308 days) then enalapril (15 mg/l) (for 175 days)100774streptozotocin (60 mg/kg/d) insulin (for 308 days)enalapril (15 mg/l) (for 175 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale364 days5CMO:0002247kidney glomerulus volume2.36x 10E6 um30.160.3578MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0dayscontrol condition100775control condition
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale427 days6CMO:0002247kidney glomerulus volume3.14x 10E6 um30.190.4654MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)100784streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale427 days6CMO:0002247kidney glomerulus volume2.44x 10E6 um30.210.5144MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100785streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale427 days6CMO:0002247kidney glomerulus volume2.4x 10E6 um30.110.2694MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days)100786streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale427 days6CMO:0002247kidney glomerulus volume2.37x 10E6 um30.150.3674MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days) and anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100787streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.kidney glomerulus morphology traitRS:0000695Crl:SDmale427 days6CMO:0002247kidney glomerulus volume2.36x 10E6 um30.240.5879MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0control condition100788control condition
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale364 days6CMO:0002954number of podocytes per kidney glomerulus158.594.5811.2187MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz308daysstreptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)100776streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 175 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale364 days6CMO:0002954number of podocytes per kidney glomerulus182.1213.4432.9211MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz308daysstreptozotocin (60 mg/kg/d) then insulin (for 308 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)100777streptozotocin (60 mg/kg/d) insulin (for 308 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 175 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale364 days6CMO:0002954number of podocytes per kidney glomerulus201.0815.036.7423MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz308daysstreptozotocin (60 mg/kg/d) then insulin (for 308 days) then enalapril (15 mg/l) (for 175 days)100778streptozotocin (60 mg/kg/d) insulin (for 308 days)enalapril (15 mg/l) (for 175 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale364 days5CMO:0002954number of podocytes per kidney glomerulus212.5911.4125.5135MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0dayscontrol condition100779control condition
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale427 days6CMO:0002954number of podocytes per kidney glomerulus158.334.5911.2432MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)100789streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-Shiga toxin 1 beta monoclonal antibody 13C4 (0.5 mg/kg/d) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale427 days6CMO:0002954number of podocytes per kidney glomerulus178.5322.4755.04MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100790streptozotocin (60 mg/kg/d) insulin (for 371 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale427 days6CMO:0002954number of podocytes per kidney glomerulus179.662.476.0502MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days)100791streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale427 days6CMO:0002954number of podocytes per kidney glomerulus201.8411.3427.7772MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0stz371daysstreptozotocin (60 mg/kg/d) then insulin (for 371 days) then enalapril (15 mg/l) (for 63 days) and anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)100792streptozotocin (60 mg/kg/d) insulin (for 371 days)enalapril (15 mg/l) (for 63 days)anti-transforming growth factor beta antibody (0.5 mg/kg/d) (for 63 days)
2522Benigni A, et al., Nephron Exp Nephrol. 2006;104(4):e158-68. Epub 2006 Aug 10.podocyte morphology traitRS:0000695Crl:SDmale427 days6CMO:0002954number of podocytes per kidney glomerulus212.5918.0544.2133MMO:0000422ex vivo light microscopy with immunohistochemistry and digital image analysis0.0control condition100793control condition
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.drinking behavior traitWater consumed (g) postsurgery per 100 g BWRS:0000695Crl:SDmale95 days to 89 days11CMO:0002859water intake drink rate to body weight ratio0.49ml/d/kg0.050.1658MMO:0000619drink intake measuring method0.0arterial catheter implantation1daysarterial catheter implantation (for 1 days)107165arterial catheter implantation (for 1 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood phosphate amountplasma PORS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000058plasma phosphate level7.33464mg/dl0.2806MMO:0000795automated plasma phosphate testautomated plasma phosphate analysis (MMO:0000795)control condition110144control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood phosphate amountplasma PORS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000058plasma phosphate level6.17232mg/dl0.3206MMO:0000795automated plasma phosphate testautomated plasma phosphate analysis (MMO:0000795)control condition110145control condition
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.blood amountRS:0000695Crl:SDmale95 days to 89 days11CMO:0003663volume of blood removed to total prehemorrhagic blood volume ratio5.83 mL/100 g of body weightvolume of blood removed to total prehemorrhagic blood volume ratio (CMO:0003663)56.8%0.20.6633MMO:0000016body weighing methodarterial catheter implantation (for 1 days) then controlled hemorrhage (between 1 and 6 hours)109134arterial catheter implantation (for 1 days)controlled hemorrhage (between 1 and 6 hours)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood calcium amountplasma calciumRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000065plasma calcium level2.38mmol/l0.02MMO:0000804automated plasma calcium testautomated plasma calcium test (MMO:0000804)control condition110148control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood calcium amountplasma calciumRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000065plasma calcium level2.38mmol/l0.04MMO:0000804automated plasma calcium test0.0automated plasma calcium test (MMO:0000804)control condition110149control condition
3077Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53.erythrocyte quantityinitial hematocrit, final hematocrit, change in hematocritRS:0000695Crl:SDmale95 days to 89 days11CMO:0002538absolute change in hematocrit11.1%1.96.3016MMO:0000215microhematocrit tube assay with visual assessment0.0arterial catheter implantation (for 1 days) then controlled hemorrhage (between 1 and 6 hours)107276arterial catheter implantation (for 1 days)controlled hemorrhage (between 1 and 6 hours)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood globulin amountplasma globulinRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0002401plasma globulin level31.16g/l0.54MMO:0000806automated plasma globulin analysisautomated plasma globulin analysis (MMO:0000806)control condition106835control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood globulin amountplasma globulinRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0002401plasma globulin level31.8g/l0.4MMO:0000806automated plasma globulin analysisautomated plasma globulin analysis (MMO:0000806)control condition106836control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood gamma-glutamyltransferase amountplasma GGT activityRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0002240plasma gamma-glutamyltransferase activity level0.6U/l0.33MMO:0000831automated plasma gamma-glutamyltransferase activity assay0.0automated plasma gamma-glutamyltransferase activity assay (MMO:0000831)control condition106863control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood gamma-glutamyltransferase amountplasma GGT activityRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0002240plasma gamma-glutamyltransferase activity level0U/l0.0MMO:0000831automated plasma gamma-glutamyltransferase activity assayautomated plasma gamma-glutamyltransferase activity assay (MMO:0000831)control condition106864control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood alkaline phosphatase amountplasma APRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0000045plasma alkaline phosphatase activity level279.8IU/l45.35MMO:0000815automated plasma alkaline phosphatase activity assaycontrol condition106875control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood alkaline phosphatase amountplasma APRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0000045plasma alkaline phosphatase activity level160.4IU/l30.09MMO:0000815automated plasma alkaline phosphatase activity assaycontrol condition106876control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood homeostasis traitcalculated plasma osmolality - mmol/kg body weightRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0002923plasma osmolality284.6umol/g0.33MMO:0000170osmometry0.0control condition111470control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood homeostasis traitcalculated plasma osmolality - mmol/kg body weightRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0002923plasma osmolality284.8umol/g1.02MMO:0000170osmometry0.0control condition111471control condition
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000633liver weight to body weight ratioweek one30g/kg0.28871.0MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days)75777controlled fructose content drinking water (5 %) (for 70 days)controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000633liver weight to body weight ratioweek one32g/kg0.98153.4MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)75779controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000633liver weight to body weight ratioweek one28g/kg0.46191.6MMO:0000005post excision weight measurement0.0controlled ethanol content drinking water (1 %) (for 70 days)75776controlled ethanol content drinking water (1 %) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000633liver weight to body weight ratioweek one32g/kg0.92383.2MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)75778controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days)
1538Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8.liver massRS:0000695Crl:SDfemale105 days12CMO:0000633liver weight to body weight ratioweek one31g/kg0.49071.7MMO:0000005post excision weight measurement0.0controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)75780controlled fructose content drinking water (5 %) (for 70 days)controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days)
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood bilirubin amounttotal plasma bilirubinRS:0000695Crl:SDfemale154 days to 91 daysN/ACMO:0002334plasma total bilirubin level0.13862mg/dl0.0244MMO:0000824automated plasma total bilirubin analysis0.0automated plasma total bilirubin analysis (MMO:0000824)control condition111467control condition
3067Demireva EY, etal., Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.blood bilirubin amounttotal plasma bilirubinRS:0000695Crl:SDmale154 days to 91 daysN/ACMO:0002334plasma total bilirubin level0.13224mg/dl0.0331MMO:0000824automated plasma total bilirubin analysis0.0automated plasma total bilirubin analysis (MMO:0000824)control condition111466control condition

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