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Study IDStudyExperiment NameExperiment NotesStrain Ont IDStrainSexAge# of AnimalsSample NotesClinical Measurement Ont IDPhenotypeFormulaClinical Measurement NotesAverage TypeValueUnitsSEMSDMethod Ont IDMethodMethod SiteMethod DurationMethod NotesPost Insult TypePost Insult Time ValuePost Insult Time UnitConditionsRecord ID
1498NBRP Hematology & Blood Biochemistry datablood albumin amountRS:0000482GK/Slcmale70 days6CMO:0000056plasma albumin level0.42g/l0.00820.02MMO:0000351automated plasma albumin analysisHitachi, model 7170 fasting (for 16 hours)78380fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood triglyceride amountRS:0000482GK/Slcmale70 days6CMO:0000548plasma triglyceride level0.6667mmol/l0.07380.1808MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78386fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood hemoglobin amountRS:0000482GK/Slcmale70 days6CMO:0000026blood hemoglobin level16.6g/dl0.20410.5MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78367fasting (for 16 hours)
41NBRP Organ Weight datalung massRS:0000482GK/Slcmale70 days6CMO:0000097lung wet weight0.978g0.03020.074MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72229specific pathogen-free condition
41NBRP Organ Weight dataspleen massRS:0000482GK/Slcmale70 days6CMO:0000149spleen weight to body weight ratio0.215%0.00610.015MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72238specific pathogen-free condition
1498NBRP Hematology & Blood Biochemistry dataerythrocyte size traitRS:0000482GK/Slcmale70 days6CMO:0000038mean corpuscular volume61.5fl0.73481.8MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78369fasting (for 16 hours)
22NBRP Body Temperature databody temperature traitRS:0000482GK/Slcmale70 days to 56 days6CMO:0000015body temperatureserial mean37.9degrees C0.12250.3MMO:0000034digital rectal thermometryspecific pathogen-free condition75065specific pathogen-free condition
41NBRP Organ Weight datakidney massRS:0000482GK/Slcmale70 days6CMO:0000140both kidneys wet weight as percentage of body weight0.752%0.03140.077MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72234specific pathogen-free condition
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood LDL cholesterol amountRS:0000482GK/Slcmale105 daysN/ACMO:0000053blood low density lipoprotein cholesterol leveln=4-629mg/dl2.1MMO:0000279blood low-density lipoprotein-cholesterol measurement test0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102901controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood LDL cholesterol amountRS:0000482GK/Slcmale105 daysN/ACMO:0000053blood low density lipoprotein cholesterol leveln=4-624.3mg/dl1.8MMO:0000279blood low-density lipoprotein-cholesterol measurement test0.0vehicle control condition102900vehicle control condition
1498NBRP Hematology & Blood Biochemistry dataerythrocyte quantityRS:0000482GK/Slcmale70 days6CMO:0000037hematocrit55%0.6941.7MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78368fasting (for 16 hours)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood cholesterol amountRS:0000482GK/Slcmale105 daysN/ACMO:0000051blood total cholesterol leveln=4-678.8mg/dl3.8MMO:0000491blood cholesterol analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102893controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood cholesterol amountRS:0000482GK/Slcmale105 daysN/ACMO:0000051blood total cholesterol leveln=4-677.8mg/dl5.2MMO:0000491blood cholesterol analysis0.0vehicle control condition102892vehicle control condition
41NBRP Organ Weight databrain massRS:0000482GK/Slcmale70 days6CMO:0000139brain weight to body weight ratio0.673%0.01510.037MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72226specific pathogen-free condition
41NBRP Organ Weight dataliver massRS:0000482GK/Slcmale70 days6CMO:0000141liver weight as percentage of body weight3.131%0.12860.315MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72232specific pathogen-free condition
14NBRP Blood Pressure and Heart Rate dataarterial blood pressure traitRS:0000482GK/Slcmale70 days to 56 days6CMO:0000004systolic blood pressureserial mean130mmHg4.490711.0MMO:0000052tail cuff photoplethysmographyNP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japanspecific pathogen-free condition75063specific pathogen-free condition
41NBRP Organ Weight datalung massRS:0000482GK/Slcmale70 days6CMO:0000156lung weight to body weight ratio0.352%0.00940.023MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72230specific pathogen-free condition
41NBRP Organ Weight dataliver massRS:0000482GK/Slcmale70 days6CMO:0000158liver wet weight8.699g0.27150.665MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72231specific pathogen-free condition
1498NBRP Hematology & Blood Biochemistry datablood creatinine amountRS:0000482GK/Slcmale70 days6CMO:0000537plasma creatinine level0.2mg/dl0.00820.02MMO:0000354automated plasma creatinine analysisHitachi, model 7170 fasting (for 16 hours)78389fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood cholesterol amountRS:0000482GK/Slcmale70 days6CMO:0000585plasma total cholesterol level99mg/dl2.04125.0MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78383fasting (for 16 hours)
41NBRP Organ Weight dataadrenal gland massRS:0000482GK/Slcmale70 days6CMO:0000164both adrenal glands wet weight36.3mg2.53116.2MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72235specific pathogen-free condition
1498NBRP Hematology & Blood Biochemistry datablood glucose amountRS:0000482GK/Slcmale70 days6CMO:0000042plasma glucose level250mg/dl8.16520.0MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78382fasting (for 16 hours)
14NBRP Blood Pressure and Heart Rate dataheart pumping traitRS:0000482GK/Slcmale70 days to 56 days6CMO:0000002heart rateserial mean446beats/min15.513438.0MMO:0000052tail cuff photoplethysmographyNP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japanspecific pathogen-free condition75064specific pathogen-free condition
41NBRP Organ Weight databrain massRS:0000482GK/Slcmale70 days6CMO:0000155brain wet weight1.871g0.01840.045MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72225specific pathogen-free condition
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood HDL cholesterol amountRS:0000482GK/Slcmale105 daysN/ACMO:0000052blood high density lipoprotein cholesterol leveln=4-67mg/dl0.7MMO:0000278blood high-density lipoprotein-cholesterol measurement test0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102897controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood HDL cholesterol amountRS:0000482GK/Slcmale105 daysN/ACMO:0000052blood high density lipoprotein cholesterol leveln=4-69mg/dl0.9MMO:0000278blood high-density lipoprotein-cholesterol measurement test0.0vehicle control condition102896vehicle control condition
1498NBRP Hematology & Blood Biochemistry datablood hemoglobin amountRS:0000482GK/Slcmale70 days6CMO:0000291mean corpuscular hemoglobin concentration30.2g/dl0.16330.4MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78371fasting (for 16 hours)
41NBRP Organ Weight dataheart massRS:0000482GK/Slcmale70 days6CMO:0000069heart wet weight0.966g0.01920.047MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72227specific pathogen-free condition
41NBRP Organ Weight datakidney massRS:0000482GK/Slcmale70 days6CMO:0000085both kidneys wet weight2.089g0.06120.15MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72233specific pathogen-free condition
1498NBRP Hematology & Blood Biochemistry datablood hemoglobin amountRS:0000482GK/Slcmale70 days6CMO:0000290mean corpuscular hemoglobin level18.6pg0.12250.3MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78370fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood HDL cholesterol amountRS:0000482GK/Slcmale70 days6CMO:0000646plasma high density lipoprotein cholesterol level66.8mg/dl0.44911.1MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78384fasting (for 16 hours)
41NBRP Organ Weight datatestis massRS:0000482GK/Slcmale70 days6CMO:0000175both testes wet weight2.551g0.04160.102MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72239specific pathogen-free condition
1498NBRP Hematology & Blood Biochemistry datablood LDL cholesterol amountRS:0000482GK/Slcmale70 days6CMO:0000647plasma low density lipoprotein cholesterol level11mg/dl0.81652.0MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78385fasting (for 16 hours)
41NBRP Organ Weight datatestis massRS:0000482GK/Slcmale70 days6CMO:0000901both testes wet weight to body weight ratio0.918%0.02490.061MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72240specific pathogen-free condition
41NBRP Organ Weight dataspleen massRS:0000482GK/Slcmale70 days6CMO:0000171spleen wet weight0.599g0.01710.042MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72237specific pathogen-free condition
41NBRP Organ Weight dataadrenal gland massRS:0000482GK/Slcmale70 days6CMO:0000621both adrenal glands weight to body weight ratio13.1mg/100g0.89812.2MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72236specific pathogen-free condition
21NBRP Body Weight databody massRS:0000482GK/Slcmale70 days6CMO:0000012body weight245g3.87849.5MMO:0000017whole body digital scalespecific pathogen-free condition70810specific pathogen-free condition
21NBRP Body Weight databody massRS:0000482GK/Slcmale42 days6CMO:0000012body weight171.7g1.95964.8MMO:0000017whole body digital scalespecific pathogen-free condition70811specific pathogen-free condition
21NBRP Body Weight databody massRS:0000482GK/Slcmale35 days6CMO:0000012body weight112.9g0.9392.3MMO:0000017whole body digital scalespecific pathogen-free condition70809specific pathogen-free condition
1498NBRP Hematology & Blood Biochemistry datablood urea nitrogen amountRS:0000482GK/Slcmale70 days6CMO:0000586plasma urea nitrogen level4.8909mmol/l0.39350.9639MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78388fasting (for 16 hours)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine outputRS:0000482GK/Slcmale105 daysN/ACMO:0000260timed urine volumen=4-629.3ml/d3.6MMO:0000147urine analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102925controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine outputRS:0000482GK/Slcmale105 daysN/ACMO:0000260timed urine volumen=4-69.6ml/d0.7MMO:0000147urine analysis0.0vehicle control condition102924vehicle control condition
1498NBRP Hematology & Blood Biochemistry datablood total protein amountRS:0000482GK/Slcmale70 days6CMO:0000054plasma total protein level64mg/ml0.40821.0MMO:0000356automated plasma total protein analysisHitachi, model 7170 fasting (for 16 hours)78379fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry databasophil quantityRS:0000482GK/Slcmale70 days6CMO:0000368blood basophil count to total leukocyte count ratio0%0.00.0MMO:0000145automated differential white blood cell count testMay-Giemsa stainingfasting (for 16 hours)78395fasting (for 16 hours)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood urea nitrogen amountRS:0000482GK/Slcmale105 daysN/ACMO:0000049blood urea nitrogen leveln=4-616.1mg/dl1.0MMO:0000253blood urea nitrogen analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102905controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood urea nitrogen amountRS:0000482GK/Slcmale105 daysN/ACMO:0000049blood urea nitrogen leveln=4-615.7mg/dl1.2MMO:0000253blood urea nitrogen analysis0.0vehicle control condition102904vehicle control condition
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood creatinine amountRS:0000482GK/Slcmale105 daysN/ACMO:0000538blood creatinine leveln=4-60.24mg/dl0.0MMO:0000270blood creatinine analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102909controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood creatinine amountRS:0000482GK/Slcmale105 daysN/ACMO:0000538blood creatinine leveln=4-60.26mg/dl0.02MMO:0000270blood creatinine analysis0.0vehicle control condition102908vehicle control condition
1498NBRP Hematology & Blood Biochemistry datablood phosphate amountRS:0000482GK/Slcmale70 days6CMO:0000058plasma phosphate level6.5mg/dl0.20410.5MMO:0000037automated blood electrolyte analysisHitachi, model 7170 fasting (for 16 hours)78390fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood coagulation traitRS:0000482GK/Slcmale70 days6CMO:0000210activated partial thromboplastin time14.5s0.57151.4MMO:0000178automated coagulometer methodSysmex, CA-3000 typefasting (for 16 hours)78375fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood coagulation traitRS:0000482GK/Slcmale70 days6CMO:0000211prothrombin time13.7s0.16330.4MMO:0000178automated coagulometer methodSysmex, CA-3000 typefasting (for 16 hours)78374fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry dataeosinophil quantityRS:0000482GK/Slcmale70 days6CMO:0000369blood eosinophil count to total leukocyte count ratio1%0.40821.0MMO:0000145automated differential white blood cell count testMay-Giemsa stainingfasting (for 16 hours)78396fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry dataeffector T cell quantityRS:0000482GK/Slcmale70 days6CMO:0000371blood lymphocyte count to total leukocyte count ratio87%1.22473.0MMO:0000145automated differential white blood cell count testMay-Giemsa stainingfasting (for 16 hours)78399fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datamonocyte quantityRS:0000482GK/Slcmale70 days6CMO:0000374blood monocyte count to total leukocyte count ratio0%0.00.0MMO:0000145automated differential white blood cell count testMay-Giemsa stainingfasting (for 16 hours)78400fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood calcium amountRS:0000482GK/Slcmale70 days6CMO:0000378total plasma calcium level10mg/dl0.08160.2MMO:0000037automated blood electrolyte analysisHitachi, model 7170 fasting (for 16 hours)78391fasting (for 16 hours)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood triglyceride amountRS:0000482GK/Slcmale105 daysN/ACMO:0000118blood triglyceride leveln=4-631mg/dl3.9MMO:0000233blood triglyceride analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102889controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood triglyceride amountRS:0000482GK/Slcmale105 daysN/ACMO:0000118blood triglyceride leveln=4-652.3mg/dl7.4MMO:0000233blood triglyceride analysis0.0vehicle control condition102888vehicle control condition
1498NBRP Hematology & Blood Biochemistry datablood alkaline phosphatase amountRS:0000482GK/Slcmale70 days6CMO:0000045plasma alkaline phosphatase activity level453IU/l9.389723.0MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78378fasting (for 16 hours)
1662NBRP Urine Volume and Urine Electrolyte dataurine chloride amountRS:0000482GK/Slcmale63 days6CMO:0000382urine chloride level142mEq/L6.940217.0MMO:0000177automated urine analysis0.9% sodium chloride solution (25 ml/kg) 952100.9% sodium chloride solution (25 ml/kg)
1662NBRP Urine Volume and Urine Electrolyte dataurine potassium amountRS:0000482GK/Slcmale63 days6CMO:0002159urine potassium excretion rate to body weight ratio182uEq/100g/6 hrs5.715514.0MMO:0000177automated urine analysisAnalytical intruments, PVA alpha II0.9% sodium chloride solution (25 ml/kg) 952090.9% sodium chloride solution (25 ml/kg)
1662NBRP Urine Volume and Urine Electrolyte dataurine chloride amountRS:0000482GK/Slcmale63 days6CMO:0002158urine chloride excretion rate to body weight ratio377uEq/100g/6 hrs15.921739.0MMO:0000177automated urine analysis0.9% sodium chloride solution (25 ml/kg) 952110.9% sodium chloride solution (25 ml/kg)
1498NBRP Hematology & Blood Biochemistry dataerythrocyte quantityRS:0000482GK/Slcmale70 days6CMO:0000025red blood cell count0.895x 10E6 cells/ul0.01550.038MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78366fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry dataleukocyte quantityRS:0000482GK/Slcmale70 days6CMO:0000027white blood cell count6.1x 1000 cells/ul0.32660.8MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78372fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry dataplatelet quantityRS:0000482GK/Slcmale70 days6CMO:0000029platelet count709x 1000 cells/ul27.352667.0MMO:0000225automated cell/particle size/count analysis methodSysmex, F-800 typefasting (for 16 hours)78373fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood bilirubin amountRS:0000482GK/Slcmale70 days6CMO:0002334total plasma bilirubin leveltotal plasma bilirubin level0.08mg/dl0.00410.01MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78387fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood sodium amountRS:0000482GK/Slcmale70 days6CMO:0000060plasma sodium level144.7mmol/l0.61241.5MMO:0000037automated blood electrolyte analysisAnalytical intruments, PVA alpha IIfasting (for 16 hours)78392fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood potassium amountRS:0000482GK/Slcmale70 days6CMO:0000061plasma potassium level4.11mmol/l0.30620.75MMO:0000037automated blood electrolyte analysisAnalytical intruments, PVA alpha IIfasting (for 16 hours)78393fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood chloride amountRS:0000482GK/Slcmale70 days6CMO:0000059plasma chloride level105mmol/l0.40821.0MMO:0000037automated blood electrolyte analysisAnalytical intruments, PVA alpha IIfasting (for 16 hours)78394fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood aspartate transaminase amountRS:0000482GK/Slcmale70 days6CMO:0000043plasma aspartate aminotransferase activity level65U/l5.715514.0MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78376fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood alanine transaminase amountRS:0000482GK/Slcmale70 days6CMO:0000044plasma alanine aminotransferase activity level44U/l7.348518.0MMO:0000553automated plasma analysisPMID:15591307fasting (for 16 hours)78377fasting (for 16 hours)
1662NBRP Urine Volume and Urine Electrolyte dataurine potassium amountRS:0000482GK/Slcmale63 days6CMO:0000128urine potassium level68.6mmol/l3.83759.4MMO:0000177automated urine analysisAnalytical intruments, PVA alpha II0.9% sodium chloride solution (25 ml/kg) 952080.9% sodium chloride solution (25 ml/kg)
1662NBRP Urine Volume and Urine Electrolyte dataurine sodium amountRS:0000482GK/Slcmale63 days6CMO:0000129urine sodium level139.1mmol/l4.65411.4MMO:0000177automated urine analysisAnalytical intruments, PVA alpha II0.9% sodium chloride solution (25 ml/kg) 952060.9% sodium chloride solution (25 ml/kg)
1662NBRP Urine Volume and Urine Electrolyte dataurine outputRS:0000482GK/Slcmale63 days6CMO:0000260timed urine volume30.68ml/d2.15565.28MMO:0000511metabolic cage urine volume measurement method0.9% sodium chloride solution (25 ml/kg) 952040.9% sodium chloride solution (25 ml/kg)
1662NBRP Urine Volume and Urine Electrolyte dataurine sodium amountRS:0000482GK/Slcmale63 days6CMO:0001855urine sodium excretion rate to body weight ratio0.010416uEq/min/g5.0E-40.0013MMO:0000177automated urine analysisAnalytical intruments, PVA alpha II0.9% sodium chloride solution (25 ml/kg) 952070.9% sodium chloride solution (25 ml/kg)
1662NBRP Urine Volume and Urine Electrolyte dataurine outputRS:0000482GK/Slcmale63 days6CMO:0001968timed urine volume to body weight ratio0.0756ul/min/g0.00570.014MMO:0000511metabolic cage urine volume measurement method0.9% sodium chloride solution (25 ml/kg) 952050.9% sodium chloride solution (25 ml/kg)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood hemoglobin amountRS:0000482GK/Slcmale105 daysN/ACMO:0002786blood hemoglobin A1c levelHbA1c n=4-65.465%0.03MMO:0000169standard blood chemistry panel0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102881controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood hemoglobin amountRS:0000482GK/Slcmale105 daysN/ACMO:0002786blood hemoglobin A1c levelHbA1c n=4-65.21%0.12MMO:0000169standard blood chemistry panel0.0vehicle control condition102880vehicle control condition
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine glucose amountRS:0000482GK/Slcmale105 daysN/ACMO:0000383urine glucose leveln=4-69401mg/dl1647.7MMO:0000147urine analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102929controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine glucose amountRS:0000482GK/Slcmale105 daysN/ACMO:0000383urine glucose leveln=4-6588.3mg/dl349.4MMO:0000147urine analysis0.0vehicle control condition102928vehicle control condition
1498NBRP Hematology & Blood Biochemistry dataneutrophil quantityRS:0000482GK/Slcmale70 days6CMO:0002337blood segmented neutrophil count to total leukocyte count ratiosegmented neutrophil %12%1.22473.0MMO:0000145automated differential white blood cell count testMay-Giemsa stainingfasting (for 16 hours)78398fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry datablood albumin amountRS:0000482GK/Slcmale70 days6CMO:0002342plasma albumin to plasma total protein ratioplasma albumin to plasma total protein ratio1.820.06120.15MMO:0000352automated plasma protein analysisHitachi, model 7170 fasting (for 16 hours)78381fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry dataleukocyte quantityRS:0000482GK/Slcmale70 days6CMO:0002339non-specified leukocyte count to total leukocyte count ratiounidentified differential wbc0%0.00.0MMO:0000145automated differential white blood cell count testMay-Giemsa stainingfasting (for 16 hours)78401fasting (for 16 hours)
1498NBRP Hematology & Blood Biochemistry dataneutrophil quantityRS:0000482GK/Slcmale70 days6CMO:0002338blood band neutrophil count to total leukocyte count ratioband neutrophil %0%0.00.0MMO:0000145automated differential white blood cell count testMay-Giemsa stainingfasting (for 16 hours)78397fasting (for 16 hours)
41NBRP Organ Weight dataheart massRS:0000482GK/Slcmale70 days6CMO:0000074heart weight to body weight ratio3.48g/kg0.10210.25MMO:0000006Shimadzu electronic balance post excision weight measurementspecific pathogen-free condition72228specific pathogen-free condition
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine ketone body amountRS:0000482GK/Slcmale105 daysN/ACMO:0002897urine acetoacetone leveln=4-6321.5umol/l74.8MMO:0000147urine analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102917controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine ketone body amountRS:0000482GK/Slcmale105 daysN/ACMO:0002897urine acetoacetone leveln=4-691.5umol/l39.9MMO:0000147urine analysis0.0vehicle control condition102916vehicle control condition
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood albumin amountRS:0000482GK/Slcmale105 daysN/ACMO:0002898blood glycated albumin levelglycated albumin n=4-61.9%0.09MMO:0000169standard blood chemistry panel0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102877controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.blood albumin amountRS:0000482GK/Slcmale105 daysN/ACMO:0002898blood glycated albumin levelglycated albumin n=4-62.3%0.07MMO:0000169standard blood chemistry panel0.0vehicle control condition102876vehicle control condition
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine ketone body amountRS:0000482GK/Slcmale105 daysN/ACMO:0002896urine 3-hydroxybutyrate leveln=4-61161.8umol/l301.9MMO:0000147urine analysis0.0controlled ipragliflozin content diet (0.008 %) (for 21 days)102921controlled ipragliflozin content diet (0.008 %) (for 21 days)
2781Iuchi H, et al., Sci Rep. 2017 Sep 19;7(1):11906. doi: 10.1038/s41598-017-12106-y.urine ketone body amountRS:0000482GK/Slcmale105 daysN/ACMO:0002896urine 3-hydroxybutyrate leveln=4-6323.3umol/l92.7MMO:0000147urine analysis0.0vehicle control condition102920vehicle control condition