Study ID,Study,Experiment Name,Experiment Notes,Strain Ont ID,Strain,Sex,Age,# of Animals,Sample Notes,Clinical Measurement Ont ID,Phenotype,Formula,Clinical Measurement Notes,Average Type,Value,Units,SEM,SD,Method Ont ID,Method,Method Site,Method Duration,Method Notes,Post Insult Type,Post Insult Time Value,Post Insult Time Unit,Conditions,Record ID,Condition 1a,Condition 1b,Condition 1c,Condition 2a,Condition 2b,Condition 3a,Condition 3b,Condition 4 331,"Shull JD, et al., Mamm Genome. 2007 Sep 18;.",pituitary gland mass,,RS:0000032,ACI/SegHsd,female,266 days to 252 days,10,,CMO:0000853,pituitary gland wet weight,,,,0.0089,g,4.0E-4,0.0012,MMO:0000005,post excision weight measurement,pituitary gland,0,,,,,sham surgical control condition (between 193 and 199 days),13090,sham surgical control condition (between 193 and 199 days),,,,,,, 331,"Shull JD, et al., Mamm Genome. 2007 Sep 18;.",pituitary gland mass,,RS:0000155,BN/SsNHsd,female,266 days to 252 days,10,,CMO:0000853,pituitary gland wet weight,,,,0.0075,g,4.0E-4,0.0013,MMO:0000005,post excision weight measurement,pituitary gland,0,,,,,sham surgical control condition (between 193 and 199 days),13099,sham surgical control condition (between 193 and 199 days),,,,,,, 331,"Shull JD, et al., Mamm Genome. 2007 Sep 18;.",pituitary gland mass,,RS:0000155,BN/SsNHsd,female,266 days to 252 days,10,,CMO:0002168,binary logarithm of pituitary gland wet weight,,logarithm of pituitary wet weight,,2.89,,0.0759,0.24,MMO:0000005,post excision weight measurement,pituitary gland,0,,,,,sham surgical control condition (between 193 and 199 days),65769,sham surgical control condition (between 193 and 199 days),,,,,,, 331,"Shull JD, et al., Mamm Genome. 2007 Sep 18;.",pituitary gland mass,,RS:0000032,ACI/SegHsd,female,266 days to 252 days,10,,CMO:0002168,binary logarithm of pituitary gland wet weight,,logarithm of pituitary wet weight,,3.13,,0.0601,0.19,MMO:0000005,post excision weight measurement,pituitary gland,0,,,,,sham surgical control condition (between 193 and 199 days),65771,sham surgical control condition (between 193 and 199 days),,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,female,154 days to 84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,1.99,mmHg,0.42,0.9391,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68857,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,male,154 days to 84 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,125.3,mmHg,4.1,9.1679,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68861,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,male,154 days to 84 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,126,mmHg,5.17,11.5605,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68863,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,male,154 days to 84 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,139.9,mmHg,4.8,10.7331,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68865,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,female,154 days to 84 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,129.7,mmHg,0.8,1.7889,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68867,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,female,154 days to 84 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,131,mmHg,5.0,11.1803,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68869,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,female,154 days to 84 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,120.3,mmHg,2.4,5.3666,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68872,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,male,154 days to 84 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,9127,mmHg/s,286.0,639.5154,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68892,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,male,154 days to 84 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,10888,mmHg/s,484.0,1082.2569,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68894,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,female,154 days to 84 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,10672,mmHg/s,343.0,766.9713,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68896,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,female,154 days to 84 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,10484,mmHg/s,492.0,1100.1454,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68898,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,female,154 days to 84 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,9210,mmHg/s,296.0,661.8761,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68900,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,male,154 days to 84 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,"rate of maximum negative change in left ventricular blood pressure" mmHg/s,,6808,mmHg/s,588.0,1314.808,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68902,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,male,154 days to 84 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,5901,mmHg/s,507.0,1133.6865,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68904,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,male,154 days to 84 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,7570,mmHg/s,476.0,1064.3684,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68906,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,female,154 days to 84 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,7503,mmHg/s,375.0,838.5255,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68908,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,female,154 days to 84 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,6612,mmHg/s,308.0,688.7089,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68910,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,female,154 days to 84 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,6589,mmHg/s,296.0,661.8761,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68912,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,male,154 days to 84 days,5,,CMO:0001747,time constant of left ventricular pressure decay,,"time constant of left ventricular pressure decay",,18.6,ms,0.74,1.6547,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68914,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,male,154 days to 84 days,5,,CMO:0001747,time constant of left ventricular pressure decay,,,,13.3,ms,0.27,0.6037,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68916,sham surgical control condition,,,,,,, 1122,"Strecker TE, et al., Genetics 2005 Jan 31;.",pituitary gland mass,,RS:0000032,ACI/SegHsd,male,147 days,6,,CMO:0000853,pituitary gland wet weight,,,,0.0077,g,4.0E-4,9.0E-4,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition,69100,sham surgical control condition,,,,,,, 1122,"Strecker TE, et al., Genetics 2005 Jan 31;.",pituitary gland mass,,RS:0000185,COP/CrCrl,male,147 days,6,,CMO:0000853,pituitary gland wet weight,,,,0.0076,g,4.0E-4,0.001,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition,69102,sham surgical control condition,,,,,,, 1122,"Strecker TE, et al., Genetics 2005 Jan 31;.",pituitary gland mass,,RS:0000032,ACI/SegHsd,male,147 days,7,,CMO:0000853,pituitary gland wet weight,,,,0.0081,g,4.0E-4,0.0011,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition,69104,sham surgical control condition,,,,,,, 1122,"Strecker TE, et al., Genetics 2005 Jan 31;.",pituitary gland mass,,RS:0000185,COP/CrCrl,male,147 days,8,,CMO:0000853,pituitary gland wet weight,,,,0.0095,g,0.001,0.0027,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition,69106,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,female,154 days to 84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,0.22,mmHg,0.25,0.559,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68859,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,male,154 days to 84 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,"rate of maximum positive change in left ventricular blood pressure" mmHg/s,,9876,mmHg/s,495.0,1106.8536,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68890,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,male,154 days to 84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,1.32,mmHg,0.3,0.6708,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68802,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,male,154 days to 84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,0.23,mmHg,0.46,1.0286,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68804,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,male,154 days to 84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,0.52,mmHg,0.27,0.6037,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68806,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,female,154 days to 84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,1.66,mmHg,0.62,1.3864,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68808,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,male,154 days to 84 days,5,,CMO:0001747,time constant of left ventricular pressure decay,,,,7.5,ms,0.6,1.3416,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68918,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001068,WKY/Cfd,female,154 days to 84 days,5,,CMO:0001747,time constant of left ventricular pressure decay,,,,11.1,ms,0.5,1.118,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68920,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001023,WKHA/Cfd,female,154 days to 84 days,5,,CMO:0001747,time constant of left ventricular pressure decay,,,,13.5,ms,1.8,4.0249,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68922,sham surgical control condition,,,,,,, 1014,"Souzeau E, et al., Hypertension. 2006 Jan;47(1):128-33. Epub 2005 Dec 12.",heart left ventricular blood pressure trait,,RS:0001600,WKY.WKHA-(D5Rat45-D5Rat245)/Cfd,female,154 days to 84 days,5,,CMO:0001747,time constant of left ventricular pressure decay,,,,7.5,ms,0.9,2.0125,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,68924,sham surgical control condition,,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0000012,body weight,,,,291,g,10.0,24.4949,MMO:0000016,body weighing method,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours),98756,sham surgical control condition (for 6 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0000012,body weight,,,,271,g,6.0,14.6969,MMO:0000016,body weighing method,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours),98772,sham surgical control condition (for 12 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0000012,body weight,,,,282,g,16.0,39.1918,MMO:0000016,body weighing method,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days),98774,sham surgical control condition (for 2 days),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0000012,body weight,,,,284,g,4.0,9.798,MMO:0000016,body weighing method,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours),98776,sham surgical control condition (between 120 and 12 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart mass,,RS:0000681,SD,male,0 days,6,,CMO:0000074,heart weight to body weight ratio,g/g*103,,,3.3,g/kg,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours),98778,sham surgical control condition (for 6 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart mass,,RS:0000681,SD,male,0 days,6,,CMO:0000074,heart weight to body weight ratio,g/g*103,,,3.4,g/kg,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours),98780,sham surgical control condition (for 12 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart mass,,RS:0000681,SD,male,0 days,6,,CMO:0000074,heart weight to body weight ratio,g/g*103,,,3.3,g/kg,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days),98782,sham surgical control condition (for 2 days),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart mass,,RS:0000681,SD,male,0 days,6,,CMO:0000074,heart weight to body weight ratio,g/g*103,,,3.4,g/kg,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours),98784,sham surgical control condition (between 120 and 12 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,5,mmHg,2.0,4.899,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98819,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,2,mmHg,1.0,2.4495,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98821,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,2,mmHg,1.0,2.4495,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98823,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,2,mmHg,1.0,2.4495,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98825,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,3,mmHg,1.0,2.4495,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98827,sham surgical control condition (for 2 days),,,vehicle control condition (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,3,mmHg,1.0,2.4495,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98829,sham surgical control condition (for 2 days),,,metoprolol (100 mg/kg/d) (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000605,left ventricular end-systolic blood pressure,,,,58,mmHg,3.0,7.3485,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98831,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000605,left ventricular end-systolic blood pressure,,,,62,mmHg,2.0,4.899,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98833,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000605,left ventricular end-systolic blood pressure,,,,66,mmHg,3.0,7.3485,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98835,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000605,left ventricular end-systolic blood pressure,,,,58,mmHg,2.0,4.899,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98837,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000605,left ventricular end-systolic blood pressure,,,,64,mmHg,3.0,7.3485,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98839,sham surgical control condition (for 2 days),,,vehicle control condition (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000605,left ventricular end-systolic blood pressure,,,,64,mmHg,3.0,7.3485,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98841,sham surgical control condition (for 2 days),,,metoprolol (100 mg/kg/d) (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.4,,0.4,0.9798,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98867,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.5,,0.5,1.2247,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98869,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.6,,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98871,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.4,,0.4,0.9798,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98873,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle mass,,RS:0000681,SD,male,0 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,g/g*103,,,2.3,mg/g,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then vehicle control condition (for 2 days),98875,sham surgical control condition (for 2 days),,,vehicle control condition (for 2 days),,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle mass,,RS:0000681,SD,male,0 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,g/g*103,,,2.5,mg/g,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days),98877,sham surgical control condition (for 2 days),,,metoprolol succinate (100 mg/kg/d) (for 2 days),,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",cardiac output trait,,RS:0000681,SD,male,0 days,6,,CMO:0000180,ejection fraction,,,,65,%,2.0,4.899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98879,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",cardiac output trait,,RS:0000681,SD,male,0 days,6,,CMO:0000180,ejection fraction,,,,63,%,3.0,7.3485,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98881,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",cardiac output trait,,RS:0000681,SD,male,0 days,6,,CMO:0000180,ejection fraction,,,,65,%,3.0,7.3485,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98883,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",cardiac output trait,,RS:0000681,SD,male,0 days,6,,CMO:0000180,ejection fraction,,,,64,%,3.0,7.3485,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98885,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7.2,mm,0.3,0.7348,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98843,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7.3,mm,0.3,0.7348,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98845,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7.1,mm,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98847,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7.1,mm,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98849,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4.2,mm,0.3,0.7348,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98851,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000983,heart left ventricle end-systolic diameter,,,,3.8,mm,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98853,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4,mm,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98855,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,0 days,6,,CMO:0000983,heart left ventricle end-systolic diameter,,,,3.9,mm,0.3,0.7348,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98857,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle posterior wall thickness,,RS:0000681,SD,male,0 days,6,,CMO:0002597,heart left ventricle end-diastolic posterior wall thickness,,,,1.6,mm,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98859,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle posterior wall thickness,,RS:0000681,SD,male,0 days,6,,CMO:0002597,heart left ventricle end-diastolic posterior wall thickness,,,,1.6,mm,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98861,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle posterior wall thickness,,RS:0000681,SD,male,0 days,6,,CMO:0002597,heart left ventricle end-diastolic posterior wall thickness,,,,1.6,mm,0.2,0.4899,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98863,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle posterior wall thickness,,RS:0000681,SD,male,0 days,6,,CMO:0002597,heart left ventricle end-diastolic posterior wall thickness,,,,1.6,mm,0.1,0.2449,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98865,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,8231,mmHg/s,423.0,1036.1342,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98887,sham surgical control condition (for 2 days),,,vehicle control condition (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,7985,mmHg/s,200.0,489.8979,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98889,sham surgical control condition (for 2 days),,,metoprolol (100 mg/kg/d) (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-7197,mmHg/s,303.0,742.1954,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98891,sham surgical control condition (for 2 days),,,vehicle control condition (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-7212,mmHg/s,416.0,1018.9877,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98893,sham surgical control condition (for 2 days),,,metoprolol succinate (100 mg/kg/d) (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours), 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle mass,,RS:0000681,SD,male,0 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,g/g*103,,,2.2,mg/g,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours),98786,sham surgical control condition (for 6 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle mass,,RS:0000681,SD,male,0 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,g/g*103,,,2.3,mg/g,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours),98788,sham surgical control condition (for 12 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle mass,,RS:0000681,SD,male,0 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,g/g*103,,,2.2,mg/g,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days),98790,sham surgical control condition (for 2 days),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart left ventricle mass,,RS:0000681,SD,male,0 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,g/g*103,,,2.3,mg/g,0.1,0.2449,MMO:0000005,post excision weight measurement,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours),98792,sham surgical control condition (between 120 and 12 hours),,,,,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart pumping trait,,RS:0000681,SD,male,0 days,6,,CMO:0000002,heart rate,,,,385,beats/min,11.0,26.9444,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98794,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart pumping trait,,RS:0000681,SD,male,0 days,6,,CMO:0000002,heart rate,,,,395,beats/min,11.0,26.9444,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98796,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart pumping trait,,RS:0000681,SD,male,0 days,6,,CMO:0000002,heart rate,,,,389,beats/min,9.0,22.0454,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98798,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart pumping trait,,RS:0000681,SD,male,0 days,6,,CMO:0000002,heart rate,,,,365,beats/min,15.0,36.7423,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98800,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart pumping trait,,RS:0000681,SD,male,0 days,6,,CMO:0000002,heart rate,,,,380,beats/min,10.0,24.4949,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98802,sham surgical control condition (for 2 days),,,vehicle control condition (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours), 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",heart pumping trait,,RS:0000681,SD,male,0 days,6,,CMO:0000002,heart rate,,,,365,beats/min,7.0,17.1464,MMO:0000107,HP Sonos 5500 echo ultrasound,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then metoprolol succinate (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98805,sham surgical control condition (for 2 days),,,metoprolol succinate (100 mg/kg/d) (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours), 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000009,mean arterial blood pressure,,,,103,mmHg,6.0,14.6969,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,360,min,sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98807,sham surgical control condition (for 6 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000009,mean arterial blood pressure,,,,90,mmHg,5.0,12.2474,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,720,min,sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98809,sham surgical control condition (for 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000009,mean arterial blood pressure,,,,76,mmHg,2.0,4.899,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98811,sham surgical control condition (for 2 days),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) ,,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000009,mean arterial blood pressure,,,,85,mmHg,3.0,7.3485,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,5,days,sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours),98813,sham surgical control condition (between 120 and 12 hours),,,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) (for 0 hours),,, 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000009,mean arterial blood pressure,,,,86,mmHg,4.0,9.798,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then vehicle control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98815,sham surgical control condition (for 2 days),,,vehicle control condition (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2160,"Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000009,mean arterial blood pressure,,,,82,mmHg,3.0,7.3485,MMO:0000014,vascular transducer tipped catheter,,1.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then metoprolol (100 mg/kg/d) (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) ,98817,sham surgical control condition (for 2 days),,,metoprolol (100 mg/kg/d) (for 2 days),,ketamine (80 mg/kg) (for 0 hours),xylazine (10 mg/kg) , 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",cardiac output trait,,RS:0000681,SD,male,72 days,5,,CMO:0000180,ejection fraction,,,,72,%,2.0,4.4721,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99373,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",cardiac output trait,,RS:0000681,SD,male,98 days,7,,CMO:0000180,ejection fraction,,,,66,%,2.0,5.2915,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99375,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",cardiac output trait,,RS:0000681,SD,male,98 days,7,,CMO:0000180,ejection fraction,,,,67,%,2.0,5.2915,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99377,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0003200,left ventricle end-diastolic wall stress,,lved-ws,,4,g/cm2,1.0,2.2361,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99387,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0003200,left ventricle end-diastolic wall stress,,,,6,g/cm2,1.0,2.2361,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99389,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0003200,left ventricle end-diastolic wall stress,,,,4,g/cm2,1.0,2.6458,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99391,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0003200,left ventricle end-diastolic wall stress,,,,4,g/cm2,1.0,2.6458,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99393,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0003201,left ventricle end-systolic wall stress,,lves-ws,,50,g/cm2,3.0,6.7082,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99395,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0003201,left ventricle end-systolic wall stress,,,,49,g/cm2,9.0,20.1246,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99397,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0003201,left ventricle end-systolic wall stress,,,,65,g/cm2,5.0,13.2288,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99399,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0003201,left ventricle end-systolic wall stress,,,,68,g/cm2,8.0,21.166,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99401,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart pumping trait,,RS:0000681,SD,male,98 days,8,,CMO:0000002,heart rate,,,,260,beats/min,12.0,33.9411,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99215,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,175 days,10,,CMO:0003200,left ventricle end-diastolic wall stress,,,,7,g/cm2,1.0,3.1623,MMO:0000337,echocardiography,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99249,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial collagen amount,,RS:0000681,SD,male,72 days,5,,CMO:0003244,ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle,,interstitial collagen,,3.9,%,0.2,0.4472,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99403,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial collagen amount,,RS:0000681,SD,male,72 days,5,,CMO:0003244,ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle,,,,4,%,0.3,0.6708,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99405,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial collagen amount,,RS:0000681,SD,male,98 days,7,,CMO:0003244,ratio of the area occupied by interstitial collagen to the total area of the heart left ventricle,,,,3.5,%,0.1,0.2646,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99407,sham surgical control condition (for 28 days),,,,,,, 2398,"Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74.",body mass,,RS:0001834,Crl:WI(WU),male,91 days,14,,CMO:0000012,body weight,,,,334,g,8.0,29.9333,MMO:0000016,body weighing method,,0.0,,sham surgery,35,days,sham surgical control condition,100005,sham surgical control condition,,,,,,, 2398,"Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74.",arterial blood pressure trait,,RS:0001834,Crl:WI(WU),male,91 days,14,,CMO:0000009,mean arterial blood pressure,,,,105,mmHg,5.0,18.7083,MMO:0000013,vascular fluid filled catheter,,0.0,,sham surgery,35,days,sham surgical control condition,100013,sham surgical control condition,,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,lvedd/pw,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.6,,0.3,0.6708,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99357,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2398,"Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74.",arterial blood pressure trait,,RS:0001834,Crl:WI(WU),male,91 days,14,,CMO:0000009,mean arterial blood pressure,,,,103,mmHg,5.0,18.7083,MMO:0000013,vascular fluid filled catheter,,0.0,,sham surgery,35,days,sham surgical control condition,100021,sham surgical control condition,,,,,,, 2398,"Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74.",angiotensin I-converting enzyme activity,,RS:0001834,Crl:WI(WU),male,91 days,14,,CMO:0000112,plasma angiotensin I converting enzyme activity level,,,,62.2,nmol/min/mL,4.2,15.715,MMO:0000237,radioactivity measurement method,,0.0,,sham surgery,35,days,sham surgical control condition,100029,sham surgical control condition,,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",body mass,,RS:0000681,SD,male,98 days,8,,CMO:0000012,body weight,,,,359,g,20.0,56.5685,MMO:0000217,scale,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99191,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",body mass,,RS:0000681,SD,male,175 days,10,,CMO:0000012,body weight,,,,471,g,10.0,31.6228,MMO:0000217,scale,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99193,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart mass,,RS:0000681,SD,male,98 days,8,,CMO:0000017,heart weight,,,,0.98,g,0.05,0.1414,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99195,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart mass,,RS:0000681,SD,male,175 days,10,,CMO:0000017,heart weight,,,,1.26,g,0.03,0.0949,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99197,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart mass,,RS:0000681,SD,male,98 days,8,,CMO:0000074,heart weight to body weight ratio,,,,2.7,g/kg,0.1,0.2828,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99199,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart mass,,RS:0000681,SD,male,175 days,10,,CMO:0000074,heart weight to body weight ratio,,,,2.7,g/kg,0.1,0.3162,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99201,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle mass,,RS:0000681,SD,male,98 days,8,,CMO:0000530,heart left ventricle weight to body weight ratio,,,,2.1,mg/g,0.1,0.2828,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99203,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle mass,,RS:0000681,SD,male,175 days,10,,CMO:0000530,heart left ventricle weight to body weight ratio,,,,1.9,mg/g,0.1,0.3162,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99205,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart right ventricle mass,,RS:0000681,SD,male,98 days,8,,CMO:0000914,heart right ventricle weight to body weight ratio,,,,0.5,mg/g,0.1,0.2828,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99207,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart right ventricle mass,,RS:0000681,SD,male,175 days,10,,CMO:0000914,heart right ventricle weight to body weight ratio,,,,0.5,mg/g,0.1,0.3162,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99209,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",lung mass,,RS:0000681,SD,male,98 days,8,,CMO:0000096,lung weight,,,,1.46,g,0.09,0.2546,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99211,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",lung mass,,RS:0000681,SD,male,175 days,10,,CMO:0000096,lung weight,,,,1.97,g,0.06,0.1897,MMO:0000005,post excision weight measurement,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99213,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart pumping trait,,RS:0000681,SD,male,175 days,10,,CMO:0000002,heart rate,,,,217,beats/min,12.0,37.9473,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99217,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",arterial blood pressure trait,,RS:0000681,SD,male,98 days,8,,CMO:0000009,mean arterial blood pressure,,,,114,mmHg,4.0,11.3137,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99219,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",arterial blood pressure trait,,RS:0000681,SD,male,175 days,10,,CMO:0000009,mean arterial blood pressure,,,,95,mmHg,4.0,12.6491,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99221,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,8,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,2,mmHg,1.0,2.8284,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99223,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,175 days,10,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,5,mmHg,1.0,3.1623,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99225,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,8,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,8031,mmHg/s,440.0,1244.5079,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99227,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,175 days,10,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,7529,mmHg/s,445.0,1407.2136,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99229,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,8,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-7479,mmHg/s,337.0,953.1799,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99231,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,175 days,10,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-5401,mmHg/s,358.0,1132.0954,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99233,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,8,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7,mm,0.2,0.5657,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99235,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,175 days,10,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,9,mm,0.1,0.3162,MMO:0000337,echocardiography,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99237,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,98 days,8,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4.3,mm,0.3,0.8485,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99239,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,175 days,10,,CMO:0000983,heart left ventricle end-systolic diameter,,,,5.6,mm,0.1,0.3162,MMO:0000337,echocardiography,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99241,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,8,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,lvedd/pw,heart left ventricle end-diastolic dimeter to posterior wall thickness ratio,,4.8,,0.3,0.8485,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99243,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,175 days,10,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,lvedd/pw,heart left ventricle end-diastolic dimeter to posterior wall thickness ratio,,5.9,,0.3,0.9487,MMO:0000337,echocardiography,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99245,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,8,,CMO:0003200,left ventricle end-diastolic wall stress,,,,3,g/cm2,1.0,2.8284,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99247,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,8,,CMO:0003201,left ventricle end-systolic wall stress,,,,67,g/cm2,13.0,36.7696,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99251,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,175 days,10,,CMO:0003201,left ventricle end-systolic wall stress,,,,72,g/cm2,7.0,22.1359,MMO:0000337,echocardiography,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99253,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,8,,CMO:0000985,heart left ventricle fractional shortening,,,,38,%,4.0,11.3137,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99255,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,175 days,10,,CMO:0000985,heart left ventricle fractional shortening,,,,40,%,1.0,3.1623,MMO:0000337,echocardiography,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99257,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial angiotensin II amount,,RS:0000681,SD,male,98 days,8,,CMO:0003482,heart left ventricle interstitial angiotensin II level during a period of time,,heart left ventricle interstitial angiotensin II level during a period of time,,1.5,pg/hr,0.2,0.5657,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99259,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial angiotensin II amount,,RS:0000681,SD,male,175 days,8,,CMO:0003482,heart left ventricle interstitial angiotensin II level during a period of time,,heart left ventricle interstitial angiotensin II level during a period of time,,1.6,pg/hr,0.2,0.5657,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99261,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial bradykinin amount,,RS:0000681,SD,male,98 days,8,,CMO:0003481,heart left ventricle interstitial bradykinin level during a period of time,,heart left ventricle interstitial bradykinin level during a period of time,,6.4,pg/hr,0.4,1.1314,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99263,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial bradykinin amount,,RS:0000681,SD,male,175 days,8,,CMO:0003481,heart left ventricle interstitial bradykinin level during a period of time,,heart left ventricle interstitial bradykinin level during a period of time,,7.4,pg/hr,1.4,3.9598,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99265,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial norepinephrine amount,,RS:0000681,SD,male,98 days,8,,CMO:0003484,heart left ventricle interstitial norepinephrine level during a period of time,,heart left ventricle interstitial bradykinin level during a period of time,,6.2,pg/hr,1.0,2.8284,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99267,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial norepinephrine amount,,RS:0000681,SD,male,175 days,8,,CMO:0003484,heart left ventricle interstitial norepinephrine level during a period of time,,heart left ventricle interstitial bradykinin level during a period of time,,5.9,pg/hr,0.4,1.1314,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99269,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial epinephrine amount,,RS:0000681,SD,male,98 days,8,,CMO:0003483,heart left ventricle interstitial epinephrine level during a period of time,,heart left ventricle interstitial epinephrine level during a period of time,,3.5,pg/hr,0.3,0.8485,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99271,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle interstitial epinephrine amount,,RS:0000681,SD,male,175 days,8,,CMO:0003483,heart left ventricle interstitial epinephrine level during a period of time,,heart left ventricle interstitial epinephrine level during a period of time,,3.5,pg/hr,0.4,1.1314,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99273,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood angiotensin II amount,,RS:0000681,SD,male,98 days,8,,CMO:0000572,plasma angiotensin II level,,,,29,pg/ml,3.0,8.4853,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99275,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood angiotensin II amount,,RS:0000681,SD,male,175 days,8,,CMO:0000572,plasma angiotensin II level,,,,34,pg/ml,4.0,11.3137,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99277,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood bradykinin amount,,RS:0000681,SD,male,98 days,8,,CMO:0003207,plasma bradykinin level,,pl bk,,10,pg/ml,1.0,2.8284,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99279,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood bradykinin amount,,RS:0000681,SD,male,175 days,8,,CMO:0003207,plasma bradykinin level,,,,17,pg/ml,2.0,5.6569,MMO:0000073,radioimmunoassay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99281,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood norepinephrine amount,,RS:0000681,SD,male,98 days,8,,CMO:0001010,plasma norepinephrine level,,pl bk,,93,pg/ml,12.0,33.9411,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99283,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood norepinephrine amount,,RS:0000681,SD,male,175 days,8,,CMO:0001010,plasma norepinephrine level,,,,102,pg/ml,16.0,45.2548,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99285,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood epinephrine amount,,RS:0000681,SD,male,98 days,8,,CMO:0001008,plasma epinephrine level,,,,83,pg/ml,12.0,33.9411,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99287,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",blood epinephrine amount,,RS:0000681,SD,male,175 days,8,,CMO:0001008,plasma epinephrine level,,,,75,pg/ml,6.0,16.9706,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,sham ACF,105,days,sham surgical control condition (for 105 days),99289,sham surgical control condition (for 105 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart pumping trait,,RS:0000681,SD,male,72 days,5,,CMO:0000002,heart rate,,,,359,beats/min,6.0,13.4164,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99291,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart pumping trait,,RS:0000681,SD,male,72 days,5,,CMO:0000002,heart rate,,,,371,beats/min,4.0,8.9443,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99293,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart pumping trait,,RS:0000681,SD,male,98 days,7,,CMO:0000002,heart rate,,,,321,beats/min,7.0,18.5203,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99295,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart pumping trait,,RS:0000681,SD,male,98 days,7,,CMO:0000002,heart rate,,,,312,beats/min,5.0,13.2288,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99297,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",arterial blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0000009,mean arterial blood pressure,,,,100,mmHg,2.0,4.4721,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99299,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",arterial blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0000009,mean arterial blood pressure,,,,106,mmHg,1.0,2.2361,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99301,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",arterial blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0000009,mean arterial blood pressure,,,,107,mmHg,3.0,7.9373,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99303,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",arterial blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0000009,mean arterial blood pressure,,,,106,mmHg,5.0,13.2288,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99305,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,6,mmHg,1.0,2.2361,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99307,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,5,mmHg,1.0,2.2361,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99309,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,4.2,mmHg,0.0,0.0,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99311,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,4,mmHg,1.0,2.6458,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99313,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,55,mmHg,3.0,6.7082,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99315,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,,,,58,mmHg,2.0,4.4721,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99317,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0000605,left ventricular end-systolic blood pressure,,,,85,mmHg,3.0,7.9373,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99319,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0000605,left ventricular end-systolic blood pressure,,,,86,mmHg,5.0,13.2288,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99321,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,8767,mmHg/s,391.0,874.3026,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99323,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,8301,mmHg/s,442.0,988.342,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99325,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,8505,mmHg/s,450.0,1190.5881,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99327,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,7931,mmHg/s,415.0,1097.9868,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99329,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-7474,mmHg/s,152.0,339.8823,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99331,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,72 days,5,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-8474,mmHg/s,123.0,275.0364,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99333,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-7379,mmHg/s,445.0,1177.3593,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99335,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricular blood pressure trait,,RS:0000681,SD,male,98 days,7,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,-7422,mmHg/s,236.0,624.3973,MMO:0000014,vascular transducer tipped catheter,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99336,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,6.9,mm,0.2,0.4472,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99339,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7,mm,0.1,0.2236,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99341,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,7,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7.7,mm,0.2,0.5292,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99343,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,7,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7.6,mm,0.1,0.2646,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99345,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4,mm,0.2,0.4472,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99347,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4.1,mm,0.2,0.4472,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99349,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,98 days,7,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4.7,mm,0.2,0.5292,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99351,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-systolic diameter,,RS:0000681,SD,male,98 days,7,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4.7,mm,0.2,0.5292,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99353,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,lvedd/pw,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.6,,0.2,0.4472,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99355,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,7,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,lvedd/pw,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.2,,0.2,0.5292,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99359,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,7,,CMO:0003471,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,lvedd/pw,heart left ventricle end-diastolic diameter to posterior wall thickness ratio,,4.5,,0.4,1.0583,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days),99361,sham surgical control condition (for 28 days),,,Aprotinin (12000 kIU) (for 28 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0000985,heart left ventricle fractional shortening,,ledd/pw,,41,%,2.0,4.4721,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99363,sham surgical control condition (for 2 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,72 days,5,,CMO:0000985,heart left ventricle fractional shortening,,,,43,%,2.0,4.4721,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days),99365,sham surgical control condition (for 2 days),,,Aprotinin (12000 kIU) (for 2 days),,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",heart left ventricle end-diastolic diameter,,RS:0000681,SD,male,98 days,7,,CMO:0000985,heart left ventricle fractional shortening,,,,38,%,2.0,5.2915,MMO:0000337,echocardiography,,0.0,,sham ACF,28,days,sham surgical control condition (for 28 days),99367,sham surgical control condition (for 28 days),,,,,,, 2278,"Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29.",cardiac output trait,,RS:0000681,SD,male,72 days,5,,CMO:0000180,ejection fraction,,,,66,%,3.0,6.7082,MMO:0000337,echocardiography,,0.0,,sham ACF,2,days,sham surgical control condition (for 2 days),99371,sham surgical control condition (for 2 days),,,,,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000004,systolic blood pressure,undefined,,,123,mmHg,5.0,11.1803,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101347,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000004,systolic blood pressure,undefined,,,129,mmHg,6.0,13.4164,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101349,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000004,systolic blood pressure,undefined,,,130,mmHg,2.0,4.4721,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101351,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000004,systolic blood pressure,undefined,,,151,mmHg,5.0,11.1803,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,2,days,controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days),101355,controlled losartan content drinking water (10 mg/kg/d) (for 3 days),,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000004,systolic blood pressure,undefined,,,150,mmHg,4.0,9.798,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,2,days,vehicle control condition then sham surgical control condition (for 2 days),101357,vehicle control condition,,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000004,systolic blood pressure,undefined,,,143,mmHg,5.0,12.2474,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101359,controlled losartan content drinking water (10 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000004,systolic blood pressure,undefined,,,160,mmHg,4.0,8.9443,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101361,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000004,systolic blood pressure,undefined,,,130,mmHg,3.0,7.3485,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101363,controlled losartan content drinking water (10 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000004,systolic blood pressure,undefined,,,165,mmHg,7.0,15.6525,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101365,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000002,heart rate,,,,366,beats/min,14.0,31.305,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101367,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000002,heart rate,,,,406,beats/min,22.0,49.1935,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101369,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000002,heart rate,,,,402,beats/min,31.0,69.3181,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101371,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000002,heart rate,,,,358,beats/min,12.0,26.8328,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101373,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000776,heart left ventricle weight,,,,0.208,g,0.006,0.0147,MMO:0000005,post excision weight measurement,,0.0,,sham acf,2,days,controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days),101399,controlled losartan content drinking water (10 mg/kg/d) (for 3 days),,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000776,heart left ventricle weight,,,,0.211,g,0.004,0.0098,MMO:0000005,post excision weight measurement,,0.0,,sham acf,2,days,vehicle control condition then sham surgical control condition (for 2 days),101401,vehicle control condition,,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000776,heart left ventricle weight,,,,0.206,g,0.005,0.0122,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101403,controlled losartan content drinking water (10 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000776,heart left ventricle weight,,,,0.214,g,0.004,0.0089,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101405,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000776,heart left ventricle weight,,,,0.195,g,0.005,0.0122,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101407,controlled losartan content drinking water (10 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000776,heart left ventricle weight,,,,0.196,g,0.004,0.0098,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101409,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",adrenal gland mass,,RS:0000681,SD,male,0 days,6,,CMO:0000143,adrenal gland weight,,,,46,mg,0.8165,2.0,MMO:0000005,post excision weight measurement,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101599,sham surgical control condition (for 28 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",kidney glomerulus integrity trait,,RS:0000681,SD,male,0 days,6,,CMO:0001269,kidney sclerotic glomeruli count to total glomeruli count ratio,,,,1.9,%,0.4899,1.2,MMO:0000561,ex vivo light microscopy with histochemistry,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101603,sham surgical control condition (for 28 days),,,,,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000002,heart rate,,,,382,beats/min,8.0,17.8885,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101388,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000776,heart left ventricle weight,,,,0.194,g,0.005,0.0112,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101389,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",body mass,,RS:0001481,SS/JrHsd,female,112 days,6,,CMO:0000012,body weight,,,,281.5,g,4.1,10.0429,MMO:0000016,body weighing method,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102340,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",kidney mass,,RS:0001481,SS/JrHsd,female,112 days,6,,CMO:0000085,both kidneys wet weight,,,,1.77,g,0.04,0.098,MMO:0000005,post excision weight measurement,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102346,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",kidney mass,,RS:0001454,SR/JrHsd,female,112 days,6,,CMO:0000085,both kidneys wet weight,,,,1.57,g,0.04,0.098,MMO:0000005,post excision weight measurement,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102349,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",uterus mass,,RS:0001481,SS/JrHsd,female,112 days,6,,CMO:0002416,uterus weight,,,,0.44,g,0.02,0.049,MMO:0000005,post excision weight measurement,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102352,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",uterus mass,,RS:0001454,SR/JrHsd,female,112 days,6,,CMO:0002416,uterus weight,,,,0.41,g,0.02,0.049,MMO:0000005,post excision weight measurement,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102355,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",body mass,,RS:0001454,SR/JrHsd,female,112 days,6,,CMO:0000012,body weight,,,,253.5,g,4.9,12.0025,MMO:0000016,body weighing method,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102343,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000002,heart rate,,,,366,beats/min,12.0,26.8328,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101383,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000002,heart rate,,,,407,beats/min,16.0,39.1918,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,7,days,controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101385,controlled losartan content drinking water (10 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",blood estradiol amount,,RS:0001481,SS/JrHsd,female,112 days,6,,CMO:0000563,plasma estradiol level,,,,15.7,pg/ml,1.7,4.1641,MMO:0000073,radioimmunoassay,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102358,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2686,"Esqueda ME, et al., Hypertension. 2007 Oct;50(4):768-72. Epub 2007 Aug 13.",blood estradiol amount,,RS:0001454,SR/JrHsd,female,112 days,6,,CMO:0000563,plasma estradiol level,,,,17.1,pg/ml,4.6,11.2677,MMO:0000073,radioimmunoassay,,0.0,,sham ovx,63,days,controlled sodium content diet (0.1 %) (for 112 days) then sham surgical control condition (between 56 and 63 days),102361,controlled sodium content diet (0.1 %) (for 112 days),,,sham surgical control condition (between 56 and 63 days),,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",kidney mass,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000082,right kidney wet weight,,,,1.378,g,0.0706,0.2446,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100371,sham surgical control condition (for 196 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",body mass,,RS:0001833,Crl:WI(Han),female,87 days,6,,CMO:0000012,body weight,,,,292,g,13.0,31.8434,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition (for 24 days),102930,sham surgical control condition (for 24 days),,,,,,, 2561,"Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000.",renin activity,,RS:0000592,MW,male,0 days,7,,CMO:0000116,plasma renin activity level,,,,9.1,ng/ml/h,0.5,1.3229,MMO:0000073,radioimmunoassay,,0.0,,sham surgery,28,days,sham surgical control condition (for 28 days),101043,sham surgical control condition (for 28 days),,,,,,, 2561,"Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000.",urine sodium amount,,RS:0000592,MW,male,0 days,7,,CMO:0000760,urine sodium excretion rate,,,,1.28,mEq/d,0.07,0.1852,MMO:0000729,flame photometry,,0.0,,sham surgery,28,days,sham surgical control condition (for 28 days),101047,sham surgical control condition (for 28 days),,,,,,, 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood sodium amount,,RS:0000785,SR/Hsd,male,119 days to 91 days,6,,CMO:0000060,plasma sodium level,,,,140.8,mmol/l,1.6,3.9192,MMO:0000039,flame atomic emission spectrometry,,0.0,,,,,controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102249,controlled sodium content diet (0.4 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood sodium amount,,RS:0000785,SR/Hsd,male,119 days to 91 days,6,,CMO:0000060,plasma sodium level,,,,139.8,mmol/l,0.7,1.7146,MMO:0000039,flame atomic emission spectrometry,,0.0,,,,,controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102251,controlled sodium content diet (8 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood sodium amount,,RS:0000922,SS/Hsd,male,119 days to 91 days,6,,CMO:0000060,plasma sodium level,,,,140.3,mmol/l,1.3,3.1843,MMO:0000039,flame atomic emission spectrometry,,0.0,,,,,controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102253,controlled sodium content diet (0.4 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood sodium amount,,RS:0000922,SS/Hsd,male,119 days to 91 days,6,,CMO:0000060,plasma sodium level,,,,138.9,mmol/l,1.2,2.9394,MMO:0000039,flame atomic emission spectrometry,,0.0,,,,,controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102255,controlled sodium content diet (8 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood molecular composition trait,,RS:0000785,SR/Hsd,male,119 days to 91 days,6,,CMO:0002923,plasma osmolality,,p osmolality mosm/kg,,298.6,umol/g,3.8,9.3081,MMO:0000170,osmometry,,0.0,,,,,controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102257,controlled sodium content diet (0.4 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood molecular composition trait,,RS:0000785,SR/Hsd,male,119 days to 91 days,6,,CMO:0002923,plasma osmolality,,p osmolality mosm/kg,,298.7,umol/g,3.2,7.8384,MMO:0000170,osmometry,,0.0,,,,,controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102259,controlled sodium content diet (8 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood molecular composition trait,,RS:0000922,SS/Hsd,male,119 days to 91 days,6,,CMO:0002923,plasma osmolality,,p osmolality mosm/kg,,301.4,umol/g,4.2,10.2879,MMO:0000170,osmometry,,0.0,,,,,controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102261,controlled sodium content diet (0.4 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2682,"Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13.",blood molecular composition trait,,RS:0000922,SS/Hsd,male,119 days to 91 days,6,,CMO:0002923,plasma osmolality,,p osmolality mosm/kg,,299.4,umol/g,3.8,9.3081,MMO:0000170,osmometry,,0.0,,,,,controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days),102263,controlled sodium content diet (8 %) (for 21 days),,,intracerebroventricular cannula implantation,,scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days),,sham surgical control condition (for 21 days) 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0000012,body weight,,,,336,g,6.532,16.0,MMO:0000016,body weighing method,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101535,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0002045,change in body weight,,change from surgery weight,,84,g,4.899,12.0,MMO:0000016,body weighing method,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101539,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",kidney mass,,RS:0000681,SD,male,0 days,6,,CMO:0000083,left kidney wet weight,,remnant kidney,,1.11,g,0.0245,0.06,MMO:0000005,post excision weight measurement,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101543,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000004,systolic blood pressure,undefined,,,118,mmHg,3.6742,9.0,MMO:0000031,tail cuff plethysmography,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101547,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",total urine protein amount,,RS:0000681,SD,male,0 days,6,,CMO:0000756,urine total protein excretion rate,,,,10,mg/d,0.8165,2.0,MMO:0000334,urine protein analysis,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101551,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",blood aldosterone amount,,RS:0000681,SD,male,0 days,6,,CMO:0000551,plasma aldosterone level,,,,50,pg/ml,4.899,12.0,MMO:0000313,plasma aldosterone analysis,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101555,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",adrenal gland mass,,RS:0000681,SD,male,0 days,6,,CMO:0000143,adrenal gland weight,,,,51,mg,1.633,4.0,MMO:0000005,post excision weight measurement,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101559,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",renin activity,,RS:0000681,SD,male,0 days,6,,CMO:0000116,plasma renin activity level,,,,3.1,ng/ml/h,0.2858,0.7,MMO:0000073,radioimmunoassay,,0.0,,sham unx,13,days,sham surgical control condition (between 12 and 14 days),101563,sham surgical control condition (between 12 and 14 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0000012,body weight,,,,347,g,7.3485,18.0,MMO:0000016,body weighing method,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101571,sham surgical control condition (for 28 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",body mass,,RS:0000681,SD,male,0 days,6,,CMO:0002045,change in body weight,,change from surgery weight,,99,g,6.532,16.0,MMO:0000016,body weighing method,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101575,sham surgical control condition (for 28 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",kidney mass,,RS:0000681,SD,male,0 days,6,,CMO:0000083,left kidney wet weight,,remnant kidney,,1.19,g,0.0327,0.08,MMO:0000005,post excision weight measurement,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101579,sham surgical control condition (for 28 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",arterial blood pressure trait,,RS:0000681,SD,male,0 days,6,,CMO:0000004,systolic blood pressure,undefined,,,118,mmHg,4.0825,10.0,MMO:0000031,tail cuff plethysmography,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101583,sham surgical control condition (for 28 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",heart mass,,RS:0000681,SD,male,0 days,6,,CMO:0000069,heart wet weight,,,,1.03,g,0.0204,0.05,MMO:0000005,post excision weight measurement,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101587,sham surgical control condition (for 28 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",total urine protein amount,,RS:0000681,SD,male,0 days,6,,CMO:0000756,urine total protein excretion rate,,,,19,mg/d,2.4495,6.0,MMO:0000334,urine protein analysis,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101591,sham surgical control condition (for 28 days),,,,,,, 2602,"Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8.",blood potassium amount,,RS:0000681,SD,male,0 days,6,,CMO:0000061,plasma potassium level,,,,5,mmol/l,0.2449,0.6,MMO:0000030,ex vivo blood analysis,,0.0,,sham unx,28,days,sham surgical control condition (for 28 days),101595,sham surgical control condition (for 28 days),,,,,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000776,heart left ventricle weight,,,,0.22,g,0.007,0.0157,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101391,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000776,heart left ventricle weight,,,,0.204,g,0.002,0.0045,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101393,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart left ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000776,heart left ventricle weight,,,,0.214,g,0.006,0.0134,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101395,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",urine output,,RS:0000742,WKY,male,252 days to 238 days,7,,CMO:0000260,timed urine volume,,,,13.9,ml/d,1.6,4.2332,MMO:0000357,urine volume measurement method,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100374,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",blood creatinine amount,,RS:0000742,WKY,male,252 days to 238 days,6,,CMO:0000537,plasma creatinine level,,,,0.41,mg/dl,0.03,0.0735,MMO:0000306,plasma creatinine analysis,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100377,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",kidney integrity trait,,RS:0000742,WKY,male,252 days to 238 days,11,,CMO:0001258,kidney fibrotic lesion area to total kidney area ratio,,,,0.91,%,0.03,0.0995,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100383,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",kidney blood vessel morphology trait,,RS:0000742,WKY,male,252 days to 238 days,11,,CMO:0002790,artery tunica media width to artery inner diameter ratio,,,,1.89,,0.12,0.398,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100386,sham surgical control condition (for 196 days),,,,,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000777,heart right ventricle weight,,,,0.059,g,0.004,0.0089,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101411,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000776,heart left ventricle weight,,,,0.061,g,0.001,0.0022,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101413,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000777,heart right ventricle weight,,,,0.06,g,0.002,0.0045,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101415,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000777,heart right ventricle weight,,,,0.061,g,0.001,0.0022,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101417,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000777,heart right ventricle weight,,,,0.054,g,0.002,0.0049,MMO:0000005,post excision weight measurement,,0.0,,sham acf,2,days,controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days),101421,controlled losartan content drinking water (10 mg/kg/d) (for 3 days),,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000777,heart right ventricle weight,,,,0.054,g,0.002,0.0049,MMO:0000005,post excision weight measurement,,0.0,,sham acf,2,days,vehicle control condition then sham surgical control condition (for 2 days),101423,vehicle control condition,,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000777,heart right ventricle weight,,,,0.053,g,0.001,0.0024,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101425,controlled losartan content drinking water (10 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000777,heart right ventricle weight,,,,0.048,g,0.001,0.0022,MMO:0000005,post excision weight measurement,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101427,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000777,heart right ventricle weight,,,,0.046,g,0.001,0.0024,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101429,controlled losartan content drinking water (10 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart right ventricle mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000777,heart right ventricle weight,,,,0.048,g,0.002,0.0049,MMO:0000005,post excision weight measurement,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101431,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",body mass,,RS:0000681,SD,male,77 days,6,,CMO:0000012,body weight,,,,378.1,g,12.1,29.6388,MMO:0000016,body weighing method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101076,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",body mass,,RS:0000681,SD,male,189 days,6,,CMO:0000012,body weight,,,,532.2,g,20.4,49.9696,MMO:0000016,body weighing method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101078,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart mass,,RS:0000681,SD,male,77 days,6,,CMO:0000017,heart weight,,,,1.13,g,0.03,0.0735,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101080,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart mass,,RS:0000681,SD,male,189 days,6,,CMO:0000017,heart weight,,,,1.41,g,0.06,0.147,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101082,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart mass,,RS:0000681,SD,male,77 days,6,,CMO:0000074,heart weight to body weight ratio,,,,2.92,g/kg,0.04,0.098,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101084,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart mass,,RS:0000681,SD,male,189 days,6,,CMO:0000074,heart weight to body weight ratio,,,,2.66,g/kg,0.04,0.098,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101086,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",arterial blood pressure trait,,RS:0000681,SD,male,77 days,6,,CMO:0000004,systolic blood pressure,undefined,,,134,mmHg,2.0,4.899,MMO:0000031,tail cuff plethysmography,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101088,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",arterial blood pressure trait,,RS:0000681,SD,male,189 days,6,,CMO:0000004,systolic blood pressure,undefined,,,144,mmHg,2.0,4.899,MMO:0000031,tail cuff plethysmography,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101090,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left ventricle mass,,RS:0000681,SD,male,77 days,6,,CMO:0000776,heart left ventricle weight,,,,0.6,g,0.02,0.049,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101092,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left ventricle mass,,RS:0000681,SD,male,189 days,6,,CMO:0000776,heart left ventricle weight,,,,0.76,g,0.03,0.0735,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101094,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left ventricle mass,,RS:0000681,SD,male,77 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,,,,1.56,mg/g,0.03,0.0735,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101096,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left ventricle mass,,RS:0000681,SD,male,189 days,6,,CMO:0000530,heart left ventricle weight to body weight ratio,,,,1.44,mg/g,0.02,0.049,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101098,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right ventricle mass,,RS:0000681,SD,male,77 days,6,,CMO:0000777,heart right ventricle weight,,,,0.23,g,0.01,0.0245,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101100,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right ventricle mass,,RS:0000681,SD,male,189 days,6,,CMO:0000777,heart right ventricle weight,,,,0.27,g,0.01,0.0245,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101102,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right ventricle mass,,RS:0000681,SD,male,77 days,6,,CMO:0000914,heart right ventricle weight to body weight ratio,,,,0.59,mg/g,0.01,0.0245,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101104,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right ventricle mass,,RS:0000681,SD,male,189 days,6,,CMO:0000914,heart right ventricle weight to body weight ratio,,,,0.51,mg/g,0.01,0.0245,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101106,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left atrium mass,,RS:0000681,SD,male,77 days,6,,CMO:0000335,left atrium weight,,,,0.03,g,0.001,0.0024,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101108,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left atrium mass,,RS:0000681,SD,male,189 days,6,,CMO:0000335,left atrium weight,,,,0.04,g,0.003,0.0073,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101110,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left atrium mass,,RS:0000681,SD,male,77 days,6,,CMO:0002950,heart left atrium weight to body weight ratio,,law/bw,,0.07,mg/g,0.003,0.0073,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101112,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart left atrium mass,,RS:0000681,SD,male,189 days,6,,CMO:0002950,heart left atrium weight to body weight ratio,,law/bw,,0.08,mg/g,0.005,0.0122,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101114,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right atrium mass,,RS:0000681,SD,male,77 days,6,,CMO:0000336,right atrium weight,,,,0.04,g,0.002,0.0049,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101116,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right atrium mass,,RS:0000681,SD,male,189 days,6,,CMO:0000336,right atrium weight,,,,0.04,g,0.003,0.0073,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101118,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right atrium mass,,RS:0000681,SD,male,77 days,6,,CMO:0002952,heart right atrium weight to body weight ratio,,raw/bw,,0.1,mg/g,0.003,0.0073,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101120,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart right atrium mass,,RS:0000681,SD,male,189 days,6,,CMO:0002952,heart right atrium weight to body weight ratio,,raw/bw,,0.08,mg/g,0.005,0.0122,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101122,sham surgical control condition (for 140 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart septum morphology trait,,RS:0000681,SD,male,77 days,6,,CMO:0002953,heart septum weight,,septum,,0.23,g,0.01,0.0245,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,28,days,sham surgical control condition (for 28 days),101124,sham surgical control condition (for 28 days),,,,,,, 2564,"Lax CJ, et al., Clin Exp Pharmacol Physiol. 2004 Aug;31(8):512-7.",heart septum morphology trait,,RS:0000681,SD,male,189 days,6,,CMO:0002953,heart septum weight,,septum,,0.29,g,0.02,0.049,MMO:0000027,ex vivo method,,0.0,,sham lad occlusion,140,days,sham surgical control condition (for 140 days),101126,sham surgical control condition (for 140 days),,,,,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000012,body weight,,,,193,g,3.0,6.7082,MMO:0000016,body weighing method,,0.0,,sham acf,4,days,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101301,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000012,body weight,,,,188,g,1.0,2.2361,MMO:0000016,body weighing method,,0.0,,,4,days,vehicle control condition then sham surgical control condition (for 4 days),101303,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000012,body weight,,,,186,g,1.0,2.2361,MMO:0000016,body weighing method,,0.0,,sham acf,7,days,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101305,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000012,body weight,,,,180,g,2.0,4.4721,MMO:0000016,body weighing method,,0.0,,,7,days,vehicle control condition then sham surgical control condition (for 7 days),101307,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000012,body weight,,,,190,g,5.0,12.2474,MMO:0000016,body weighing method,,0.0,,sham acf,2,days,controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days),101311,controlled losartan content drinking water (10 mg/kg/d) (for 3 days),,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000012,body weight,,,,200,g,2.0,4.899,MMO:0000016,body weighing method,,0.0,,,2,days,vehicle control condition then sham surgical control condition (for 2 days),101313,vehicle control condition,,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000012,body weight,,,,184,g,2.0,4.899,MMO:0000016,body weighing method,,0.0,,sham acf,4,days,controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101315,controlled losartan content drinking water (10 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000012,body weight,,,,192,g,3.0,6.7082,MMO:0000016,body weighing method,,0.0,,,4,days,vehicle control condition then sham surgical control condition (for 4 days),101317,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000012,body weight,,,,204,g,2.0,4.899,MMO:0000016,body weighing method,,0.0,,sham acf,7,days,controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101319,controlled losartan content drinking water (10 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000012,body weight,,,,201,g,3.0,7.3485,MMO:0000016,body weighing method,,0.0,,,7,days,vehicle control condition then sham surgical control condition (for 7 days),101321,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000420,body weight gain,,change from surgery weight,,20,g,2.0,4.4721,MMO:0000016,body weighing method,,0.0,,sham acf,4,days,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101323,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000420,body weight gain,,change from surgery weight,,18,g,1.0,2.2361,MMO:0000016,body weighing method,,0.0,,,4,days,vehicle control condition then sham surgical control condition (for 4 days),101325,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000420,body weight gain,,change from surgery weight,,30,g,2.0,4.4721,MMO:0000016,body weighing method,,0.0,,sham acf,7,days,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101327,controlled ramipril content drinking water (3 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000420,body weight gain,,change from surgery weight,,34,g,2.0,4.4721,MMO:0000016,body weighing method,,0.0,,,7,days,vehicle control condition then sham surgical control condition (for 7 days),101329,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000420,body weight gain,,change from surgery weight,,-5,g,2.0,4.899,MMO:0000016,body weighing method,,0.0,,sham acf,2,days,controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days),101333,controlled losartan content drinking water (10 mg/kg/d) (for 3 days),,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000420,body weight gain,,change from surgery weight,,-6,g,1.0,2.4495,MMO:0000016,body weighing method,,0.0,,sham acf,2,days,vehicle control condition then sham surgical control condition (for 2 days),101335,vehicle control condition,,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000420,body weight gain,,change from surgery weight,,-1,g,1.0,2.4495,MMO:0000016,body weighing method,,0.0,,sham acf,4,days,controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101337,controlled losartan content drinking water (10 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000420,body weight gain,,change from surgery weight,,6,g,1.0,2.2361,MMO:0000016,body weighing method,,0.0,,sham acf,4,days,vehicle control condition then sham surgical control condition (for 4 days),101339,vehicle control condition,,,sham surgical control condition (for 4 days),,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle end-diastolic diameter,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000985,heart left ventricle fractional shortening,,,,51.5,%,1.7,3.8013,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100303,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle end-diastolic diameter,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,7.9,mm,0.2,0.4472,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100306,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle end-systolic diameter,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000983,heart left ventricle end-systolic diameter,,,,3.8,mm,0.3,0.6708,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100309,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart pumping trait,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000002,heart rate,,,,398,beats/min,37.0,82.7345,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100312,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",arterial blood pressure trait,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000004,systolic blood pressure,10 min mean,,continuous mean,97.8,mmHg,6.3,14.0872,MMO:0000014,vascular transducer tipped catheter,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) ,100315,sham surgical control condition (for 224 days),,,ketamine (80 mg/kg) ,,xylazine (10 mg/kg) ,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",arterial blood pressure trait,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000005,diastolic blood pressure,10 min mean,,continuous mean,63.3,mmHg,6.9,15.4289,MMO:0000014,vascular transducer tipped catheter,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) ,100318,sham surgical control condition (for 224 days),,,ketamine (80 mg/kg) ,,xylazine (10 mg/kg) ,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricular blood pressure trait,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000605,left ventricular end-systolic blood pressure,10 min mean,,continuous mean,93,mmHg,5.8,12.9692,MMO:0000014,vascular transducer tipped catheter,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) ,100321,sham surgical control condition (for 224 days),,,ketamine (80 mg/kg) ,,xylazine (10 mg/kg) ,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricular blood pressure trait,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,10 min mean,,continuous mean,5.5,mmHg,2.4,5.3666,MMO:0000014,vascular transducer tipped catheter,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) ,100324,sham surgical control condition (for 224 days),,,ketamine (80 mg/kg) ,,xylazine (10 mg/kg) ,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricular blood pressure trait,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,10 min mean,,continuous mean,4225,mmHg/s,525.0,1173.9357,MMO:0000014,vascular transducer tipped catheter,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days) then ketamine (80 mg/kg) then xylazine (10 mg/kg) ,100327,sham surgical control condition (for 224 days),,,ketamine (80 mg/kg) ,,xylazine (10 mg/kg) ,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",blood sodium amount,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000500,serum sodium level,,,,157.7,mmol/l,6.4,14.3108,MMO:0000142,automated serum sodium test,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100330,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",blood potassium amount,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000495,serum potassium level,,,,5.3,mmol/l,0.37,0.8273,MMO:0000141,automated serum potassium test,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100333,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle wall thickness,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000987,heart ventricle septal wall thickness,,,,0.14,cm,0.01,0.0346,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100336,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle end-diastolic diameter,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000982,heart left ventricle end-diastolic diameter,,,,8.3,mm,0.2,0.6928,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100339,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle end-systolic diameter,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000983,heart left ventricle end-systolic diameter,,,,4.9,mm,0.3,1.0392,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100342,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle posterior wall thickness,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000238,heart posterior wall thickness,,,,0.17,cm,0.01,0.0346,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100345,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle end-diastolic diameter,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000985,heart left ventricle fractional shortening,,,,41.1,%,3.0,10.3923,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100348,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",cardiac output trait,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000180,ejection fraction,,,,75.8,%,3.9,13.51,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100351,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",blood flow trait,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0002789,E/A wave ratio,,e/a wave,,1.39,,0.15,0.5196,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100354,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",kidney mass,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000082,right kidney wet weight,,,,1.378,g,0.0706,0.2446,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100357,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",urine output,,RS:0000742,WKY,male,252 days to 238 days,7,,CMO:0000260,timed urine volume,,,,13.9,ml/d,1.6,4.2332,MMO:0000357,urine volume measurement method,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100360,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",blood creatinine amount,,RS:0000742,WKY,male,252 days to 238 days,6,,CMO:0000537,plasma creatinine level,,,,0.41,mg/dl,0.03,0.0735,MMO:0000306,plasma creatinine analysis,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100363,sham surgical control condition (for 196 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",body mass,,RS:0001299,GK,female,87 days,6,,CMO:0000012,body weight,,,,229,g,5.0,12.2474,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition (for 24 days),103755,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood glucose amount,,RS:0001833,Crl:WI(Han),female,87 days,6,,CMO:0000046,blood glucose level,,,,105,mg/dl,3.0,7.3485,MMO:0000190,machine read blood glucose test strip,,0.0,,,,,sham surgical control condition (for 24 days) then fasting (for 12 hours),103757,sham surgical control condition (for 24 days),,,fasting (for 12 hours),,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood glucose amount,,RS:0001299,GK,female,87 days,6,,CMO:0000046,blood glucose level,,,,172,mg/dl,9.0,22.0454,MMO:0000190,machine read blood glucose test strip,,0.0,,,,,sham surgical control condition (for 24 days) then fasting (for 12 hours),103759,sham surgical control condition (for 24 days),,,fasting (for 12 hours),,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood insulin amount,,RS:0001833,Crl:WI(Han),female,87 days,6,,CMO:0000342,plasma insulin level,,,,221,mU/l,44.2,108.2674,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 24 days),103761,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood insulin amount,,RS:0001299,GK,female,87 days,6,,CMO:0000342,plasma insulin level,,,,26,mU/l,2.6,6.3687,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 24 days),103763,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood cholesterol amount,,RS:0001833,Crl:WI(Han),female,87 days,6,,CMO:0000585,plasma total cholesterol level,,,,2.49,mg/dl,0.17,0.4164,MMO:0000284,plasma total cholesterol measurement test,,0.0,automated plasma total cholesterol analysis,,,,sham surgical control condition (for 24 days),103765,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood cholesterol amount,,RS:0001299,GK,female,87 days,6,,CMO:0000585,plasma total cholesterol level,,,,2.53,mg/dl,0.14,0.3429,MMO:0000284,plasma total cholesterol measurement test,,0.0,automated plasma total cholesterol analysis,,,,sham surgical control condition (for 24 days),103767,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood LDL cholesterol amount,,RS:0001833,Crl:WI(Han),female,87 days,6,,CMO:0000647,plasma low density lipoprotein cholesterol level,,,,0.21,mg/dl,0.01,0.0245,MMO:0000283,plasma low-density lipoprotein-cholesterol measurement test,,0.0,automated plasma low-density lipoprotein-cholesterol analysis,,,,sham surgical control condition (for 24 days),103769,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood LDL cholesterol amount,,RS:0001299,GK,female,87 days,6,,CMO:0000647,plasma low density lipoprotein cholesterol level,,,,0.23,mg/dl,0.02,0.049,MMO:0000283,plasma low-density lipoprotein-cholesterol measurement test,,0.0,automated plasma low-density lipoprotein-cholesterol analysis,,,,sham surgical control condition (for 24 days),103771,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood estradiol amount,,RS:0001833,Crl:WI(Han),female,87 days,6,,CMO:0000563,plasma estradiol level,,,,48.6,pg/ml,9.2,22.5353,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 24 days),103773,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",blood estradiol amount,,RS:0001299,GK,female,87 days,6,,CMO:0000563,plasma estradiol level,,,,49.6,pg/ml,3.7,9.0631,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 24 days),103775,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",heart mass,,RS:0001833,Crl:WI(Han),female,87 days,6,,CMO:0000074,heart weight to body weight ratio,,,,3.2,g/kg,0.1,0.2449,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition (for 24 days),103777,sham surgical control condition (for 24 days),,,,,,, 2782,"Apaijai N, et al., Biosci Rep. 2017 Oct 17;37(5). pii: BSR20170886. doi: 10.1042/BSR20170886. Print 2017 Oct 31.",heart mass,,RS:0001299,GK,female,87 days,6,,CMO:0000074,heart weight to body weight ratio,,,,4,g/kg,0.3,0.7348,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition (for 24 days),103779,sham surgical control condition (for 24 days),,,,,,, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",body mass,,RS:0001454,SR/JrHsd,female,0 days,N/A,,CMO:0000012,body weight,,,,226,g,4.7,,MMO:0000016,body weighing method,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102183,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",body mass,,RS:0001454,SR/JrHsd,female,0 days,N/A,,CMO:0000012,body weight,,,,232,g,4.1,,MMO:0000016,body weighing method,,0.0,,,,,controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102184,controlled sodium chloride content diet (4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",body mass,,RS:0001481,SS/JrHsd,female,0 days,N/A,,CMO:0000012,body weight,,,,252,g,3.8,,MMO:0000016,body weighing method,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102189,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",body mass,,RS:0001481,SS/JrHsd,female,0 days,N/A,,CMO:0000012,body weight,,,,235,g,13.0,,MMO:0000016,body weighing method,,0.0,,,,,controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102190,controlled sodium chloride content diet (4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",kidney mass,,RS:0001454,SR/JrHsd,female,0 days,N/A,,CMO:0000084,single kidney wet weight,,,,0.86,g,0.02,,MMO:0000005,post excision weight measurement,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102195,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",kidney mass,,RS:0001454,SR/JrHsd,female,0 days,N/A,,CMO:0000084,single kidney wet weight,,,,1.05,g,0.03,,MMO:0000005,post excision weight measurement,,0.0,,,,,controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102196,controlled sodium chloride content diet (4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",kidney mass,,RS:0001481,SS/JrHsd,female,0 days,N/A,,CMO:0000084,single kidney wet weight,,,,0.87,g,0.02,,MMO:0000005,post excision weight measurement,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102201,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",kidney mass,,RS:0001481,SS/JrHsd,female,0 days,N/A,,CMO:0000084,single kidney wet weight,,,,1.26,g,0.09,,MMO:0000005,post excision weight measurement,,0.0,,,,,controlled sodium chloride content diet (4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102202,controlled sodium chloride content diet (4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",arterial blood pressure trait,,RS:0001454,SR/JrHsd,female,0 days,N/A,,CMO:0000009,mean arterial blood pressure,,,,122,mmHg,4.0,,MMO:0000013,vascular fluid filled catheter,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102207,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",arterial blood pressure trait,,RS:0001481,SS/JrHsd,female,0 days,N/A,,CMO:0000009,mean arterial blood pressure,,,,129,mmHg,5.0,,MMO:0000013,vascular fluid filled catheter,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102210,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",glomerular filtration trait,,RS:0001454,SR/JrHsd,female,0 days,N/A,,CMO:0002944,glomerular filtration rate to kidney weight ratio,,,,2.2,ml/min/g,0.31,,MMO:0000634,inulin analysis by liquid phase colorimetry,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102213,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2681,"Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1.",glomerular filtration trait,,RS:0001481,SS/JrHsd,female,0 days,N/A,,CMO:0002944,glomerular filtration rate to kidney weight ratio,,,,2.46,ml/min/g,0.06,,MMO:0000634,inulin analysis by liquid phase colorimetry,,0.0,,,,,controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days),102216,controlled sodium chloride content diet (0.4 %) (for 14 days),,,sham surgical control condition,,peanut oil (0.2 ml) (for 14 days),, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",body mass,,RS:0000742,WKY,male,56 days to 42 days,12,,CMO:0000012,body weight,,,,223,g,1.4,4.8497,MMO:0000016,body weighing method,,0.0,,lad occlusion,0,days,sham surgical control condition,100267,sham surgical control condition,,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",body mass,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000012,body weight,,,,566,g,17.0,58.8897,MMO:0000016,body weighing method,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100270,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",body mass,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000012,body weight,,,,562,g,22.0,49.1935,MMO:0000016,body weighing method,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100273,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart mass,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000017,heart weight,,,,1.187,g,0.037,0.1282,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100276,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart mass,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000017,heart weight,,,,1.266,g,0.07,0.1565,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100279,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart mass,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0001198,heart weight to tibia length ratio,,,,0.278,g/cm,0.007,0.0157,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100282,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",tibia length,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000450,tibia length,,,,4.3,cm,0.12,0.2683,MMO:0000276,post excision length measurement,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100285,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle mass,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000776,heart left ventricle weight,,,,0.847,g,0.027,0.0935,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100288,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle mass,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000776,heart left ventricle weight,,,,0.84,g,0.022,0.0492,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100291,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",heart left ventricle mass,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0002787,heart left ventricle weight to tibia length ratio,,lv/tl,,0.194,g/cm,0.005,0.0112,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100294,sham surgical control condition (for 224 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",lung mass,,RS:0000742,WKY,male,252 days to 238 days,12,,CMO:0000097,lung wet weight,,,,1.779,g,0.047,0.1628,MMO:0000005,post excision weight measurement,,0.0,,lad occlusion sham,196,days,sham surgical control condition (for 196 days),100297,sham surgical control condition (for 196 days),,,,,,, 2460,"Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29.",cardiac output trait,,RS:0000742,WKY,male,280 days to 266 days,5,,CMO:0000180,ejection fraction,,,,86.8,%,1.5,3.3541,MMO:0000337,echocardiography,,0.0,,lad occlusion sham,210,days,sham surgical control condition (for 224 days),100300,sham surgical control condition (for 224 days),,,,,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000420,body weight gain,,change from surgery weight,,8,g,2.0,4.899,MMO:0000016,body weighing method,,0.0,,sham acf,7,days,controlled losartan content drinking water (10 mg/kg/d) (for 8 days) then sham surgical control condition (for 7 days),101341,controlled losartan content drinking water (10 mg/kg/d) (for 8 days),,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",body mass,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000420,body weight gain,,change from surgery weight,,23,g,3.0,6.7082,MMO:0000016,body weighing method,,0.0,,sham acf,7,days,vehicle control condition then sham surgical control condition (for 7 days),101343,vehicle control condition,,,sham surgical control condition (for 7 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",arterial blood pressure trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000004,systolic blood pressure,undefined,,,106,mmHg,4.0,8.9443,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101345,controlled ramipril content drinking water (3 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,5,,CMO:0000002,heart rate,,,,424,beats/min,10.0,22.3607,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,2,days,controlled losartan content drinking water (10 mg/kg/d) (for 3 days) then sham surgical control condition (for 2 days),101377,controlled losartan content drinking water (10 mg/kg/d) (for 3 days),,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000002,heart rate,,,,377,beats/min,11.0,26.9444,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,2,days,vehicle control condition then sham surgical control condition (for 2 days),101379,vehicle control condition,,,sham surgical control condition (for 2 days),,,, 2585,"Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54.",heart pumping trait,,RS:0001006,WF/Mol,male,0 days,6,,CMO:0000002,heart rate,,,,410,beats/min,8.0,19.5959,MMO:0000031,tail cuff plethysmography,,0.0,,sham acf,4,days,controlled losartan content drinking water (10 mg/kg/d) (for 5 days) then sham surgical control condition (for 4 days),101381,controlled losartan content drinking water (10 mg/kg/d) (for 5 days),,,sham surgical control condition (for 4 days),,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart pumping trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000002,heart rate,,,,331,beats/min,14.0,44.2719,MMO:0000011,vascular indwelling catheter method,heart,0.0,,,,,sham surgical control condition,108838,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart pumping trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000002,heart rate,,,,364,beats/min,28.0,84.0,MMO:0000011,vascular indwelling catheter method,heart,0.0,,,,,sham surgical control condition,108840,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000009,mean arterial blood pressure,,,,94,mmHg,3.0,9.4868,MMO:0000011,vascular indwelling catheter method,aorta,0.0,,,,,sham surgical control condition,108842,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000009,mean arterial blood pressure,,,,107,mmHg,4.0,12.0,MMO:0000011,vascular indwelling catheter method,aorta,0.0,,,,,sham surgical control condition,108844,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood protein amount,,RS:0000593,MWF/Hsd,male,133 days,5,,CMO:0003868,blood B-type natriuretic peptide level,,blood B-type natriuretic peptide level (CMO:0003868),,0.3,ng/ml,0.4,0.8944,MMO:0000713,enzyme immunoassay,,0.0,,,,,sham surgical control condition,108883,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood protein amount,,RS:0004793,HsdCpb:WU,male,133 days,5,,CMO:0003868,blood B-type natriuretic peptide level,,blood B-type natriuretic peptide level (CMO:0003868),,0.6,ng/ml,0.4,0.8944,MMO:0000713,enzyme immunoassay,,0.0,,,,,sham surgical control condition,108885,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",aorta morphology trait,,RS:0004793,HsdCpb:WU,male,168 days,10,,CMO:0002790,artery tunica media width to artery inner diameter ratio,,,,0.23,,0.03,0.0949,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,aorta wall,0.0,,,,,sham surgical control condition,108886,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",aorta morphology trait,,RS:0000593,MWF/Hsd,male,168 days,9,,CMO:0002790,artery tunica media width to artery inner diameter ratio,,,,0.25,,0.2,0.6,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,aorta wall,0.0,,,,,sham surgical control condition,108888,sham surgical control condition,,,,,,, 3116,"Schulz A, etal., Physiol Genomics. 2010 Jun.",urine albumin amount,,RS:0000596,MWF/FubRkb,male,168 days,10,,CMO:0000757,urine albumin excretion rate,,,,108.7,mg/d,12.3,38.896,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition,108124,sham surgical control condition,,,,,,, 3116,"Schulz A, etal., Physiol Genomics. 2010 Jun.",urine albumin amount,,RS:0000744,SHR/FubRkb,male,84 days,10,,CMO:0000757,urine albumin excretion rate,,,,0.4,mg/d,0.1,0.3162,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition,108125,sham surgical control condition,,,,,,, 3116,"Schulz A, etal., Physiol Genomics. 2010 Jun.",urine albumin amount,,RS:0002404,SHR-Chr 6MWF/Rkb,male,84 days,10,,CMO:0000757,urine albumin excretion rate,,,,1.3,mg/d,0.3,0.9487,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition,108126,sham surgical control condition,,,,,,, 3080,"Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19.",brain oxygen amount,,RS:0002538,SHRSP/A3NCrl,male,84 days,8,,CMO:0003626,partial pressure of brain white matter oxygen,,partial pressure of brain white matter oxygen (CMO:0003626),,41.8,mmHg,2.5,7.0711,MMO:0000711,electron paramagnetic resonance oximetry,white matter,40.0,5 scans x 40 seconds,,,,sham surgical control condition then standard diet,107319,sham surgical control condition,,,standard diet,,,, 3080,"Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19.",brain oxygen amount,,RS:0002538,SHRSP/A3NCrl,male,91 days,8,,CMO:0003626,partial pressure of brain white matter oxygen,,partial pressure of brain white matter oxygen (CMO:0003626),,19.7,mmHg,3.4,9.6167,MMO:0000711,electron paramagnetic resonance oximetry,white matter,40.0,5 scans x 40 seconds,,,,sham surgical control condition then standard diet,107320,sham surgical control condition,,,standard diet,,,, 3080,"Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19.",brain oxygen amount,,RS:0002538,SHRSP/A3NCrl,male,98 days,8,,CMO:0003626,partial pressure of brain white matter oxygen,,partial pressure of brain white matter oxygen (CMO:0003626),,18,mmHg,3.4,9.6167,MMO:0000711,electron paramagnetic resonance oximetry,white matter,40.0,5 scans x 40 seconds,,,,sham surgical control condition then standard diet,107322,sham surgical control condition,,,standard diet,,,, 3080,"Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19.",brain oxygen amount,,RS:0002538,SHRSP/A3NCrl,male,105 days,8,,CMO:0003626,partial pressure of brain white matter oxygen,,partial pressure of brain white matter oxygen (CMO:0003626),,16.8,mmHg,3.7,10.4652,MMO:0000711,electron paramagnetic resonance oximetry,white matter,40.0,5 scans x 40 seconds,,,,sham surgical control condition then standard diet,107323,sham surgical control condition,,,standard diet,,,, 3080,"Weaver J, etal., J Cereb Blood Flow Metab. 2014 May;34(5):890-6. doi: 10.1038/jcbfm.2014.35. Epub 2014 Feb 19.",brain oxygen amount,,RS:0002538,SHRSP/A3NCrl,male,112 days,8,,CMO:0003626,partial pressure of brain white matter oxygen,,partial pressure of brain white matter oxygen (CMO:0003626),,15.4,mmHg,3.8,10.748,MMO:0000711,electron paramagnetic resonance oximetry,white matter,40.0,5 scans x 40 seconds,,,,sham surgical control condition then standard diet,107324,sham surgical control condition,,,standard diet,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0004793,HsdCpb:WU,male,84 days,5,,CMO:0000007,left ventricular systolic blood pressure,,,,117,mmHg,5.0,11.1803,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108774,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0004793,HsdCpb:WU,male,84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,5.3,mmHg,2.4,5.3666,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108776,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0000593,MWF/Hsd,male,84 days,5,,CMO:0000606,left ventricular end-diastolic blood pressure,,,,6.2,mmHg,1.9,4.2485,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108777,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart pumping trait,,RS:0004793,HsdCpb:WU,male,84 days,5,,CMO:0000002,heart rate,,,,359,beats/min,18.0,40.2492,MMO:0000011,vascular indwelling catheter method,heart,0.0,,,,,sham surgical control condition,108778,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",venous blood pressure trait,,RS:0004793,HsdCpb:WU,male,84 days,5,,CMO:0003657,central venous pressure,,,,1.2,mmHg,1.9,4.2485,MMO:0000011,vascular indwelling catheter method,vena cava,0.0,,,,,sham surgical control condition,108780,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",venous blood pressure trait,,RS:0000593,MWF/Hsd,male,84 days,5,,CMO:0003657,central venous pressure,,,,2.1,mmHg,1.7,3.8013,MMO:0000011,vascular indwelling catheter method,vena cava,0.0,,,,,sham surgical control condition,108781,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0000593,MWF/Hsd,male,84 days,5,,CMO:0000007,left ventricular systolic blood pressure,,,,131,mmHg,3.0,6.7082,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108775,sham surgical control condition,,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",body mass,,RS:0000744,SHR/FubRkb,male,168 days,9,,CMO:0000012,body weight,,,,329.2,g,8.2,24.6,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition (for 126 days),109549,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",body mass,,RS:0003207,SHR-Chr 8MWF/Rkb,male,168 days,9,,CMO:0000012,body weight,,,,345,g,7.8,23.4,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition (for 126 days),109551,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",kidney mass,,RS:0000744,SHR/FubRkb,male,168 days,9,,CMO:0000082,right kidney wet weight,,,,1.07,g,0.05,0.15,MMO:0000005,post excision weight measurement,kidney,0.0,,,,,sham surgical control condition (for 126 days),109553,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",kidney mass,,RS:0003207,SHR-Chr 8MWF/Rkb,male,168 days,9,,CMO:0000082,right kidney wet weight,,,,1.16,g,0.04,0.12,MMO:0000005,post excision weight measurement,kidney,0.0,,,,,sham surgical control condition (for 126 days),109554,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",kidney mass,,RS:0000744,SHR/FubRkb,male,168 days,9,,CMO:0001953,right kidney wet weight to body weight ratio,,,,3.25,mg/g,0.09,0.27,MMO:0000005,post excision weight measurement,kidney,0.0,,,,,sham surgical control condition (for 126 days),109557,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",kidney mass,,RS:0003207,SHR-Chr 8MWF/Rkb,male,168 days,9,,CMO:0001953,right kidney wet weight to body weight ratio,,,,3.36,mg/g,0.08,0.24,MMO:0000005,post excision weight measurement,kidney,0.0,,,,,sham surgical control condition (for 126 days),109558,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",urine albumin amount,,RS:0000744,SHR/FubRkb,male,168 days,9,,CMO:0000757,urine albumin excretion rate,,,,1.3,mg/d,0.3,0.9,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 42 days),109561,sham surgical control condition (for 42 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",urine albumin amount,,RS:0000744,SHR/FubRkb,male,84 days,9,,CMO:0000757,urine albumin excretion rate,,,,0.4,mg/d,0.1,0.3,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 42 days),109562,sham surgical control condition (for 42 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",urine albumin amount,,RS:0003207,SHR-Chr 8MWF/Rkb,male,168 days,9,,CMO:0000757,urine albumin excretion rate,,,,10.8,mg/d,2.1,6.3,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 126 days),109563,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",urine albumin amount,,RS:0003207,SHR-Chr 8MWF/Rkb,male,84 days,9,,CMO:0000757,urine albumin excretion rate,,,,1.3,mg/d,0.2,0.6,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 42 days),109564,sham surgical control condition (for 42 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",blood cystatin C amount,,RS:0000744,SHR/FubRkb,male,168 days,9,,CMO:0002778,plasma cystatin C level,,,,0.05,mg/l,0.003,0.009,MMO:0000352,automated plasma protein analysis,,0.0,,,,,sham surgical control condition (for 126 days),109566,sham surgical control condition (for 126 days),,,,,,, 3148,"Schulz A, etal., Physiol Genomics. 2012 Jan 18;44(1):110-6. Epub 2011 Nov 22.",blood cystatin C amount,,RS:0003207,SHR-Chr 8MWF/Rkb,male,168 days,9,,CMO:0002778,plasma cystatin C level,,,,0.05,mg/l,0.002,0.006,MMO:0000352,automated plasma protein analysis,,0.0,,,,,sham surgical control condition (for 126 days),109568,sham surgical control condition (for 126 days),,,,,,, 3116,"Schulz A, etal., Physiol Genomics. 2010 Jun.",urine albumin amount,,RS:0000596,MWF/FubRkb,male,84 days,10,,CMO:0000757,urine albumin excretion rate,,,,22.8,mg/d,2.1,6.6408,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition,108123,sham surgical control condition,,,,,,, 3116,"Schulz A, etal., Physiol Genomics. 2010 Jun.",urine albumin amount,,RS:0002404,SHR-Chr 6MWF/Rkb,male,168 days,10,,CMO:0000757,urine albumin excretion rate,,,,0.5,mg/d,0.2,0.6325,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition,108127,sham surgical control condition,,,,,,, 3119,"Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2.",liver integrity trait,,RS:0002249,WAG/RijCrl,male,87 days,10,,CMO:0003611,number of small metastatic liver tumors,,metastatic liver tumor count by size,,1.7,,0.9,2.846,MMO:0000514,ex vivo caliper method,,0.0,,S4MH injection,21,days,S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days),108152,S4MH cells (250 X 10E3) (for 21 days),,,sham surgical control condition (for 11 days),,,, 3119,"Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2.",liver integrity trait,,RS:0002249,WAG/RijCrl,male,87 days,10,,CMO:0003612,number of medium-sized metastatic liver tumors,,metastatic liver tumor count by size,,4.3,,1.1,3.4785,MMO:0000514,ex vivo caliper method,,0.0,,S4MH injection,21,days,S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days),108153,S4MH cells (250 X 10E3) (for 21 days),,,sham surgical control condition (for 11 days),,,, 3119,"Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2.",liver integrity trait,,RS:0002249,WAG/RijCrl,male,87 days,10,,CMO:0003613,number of large metastatic liver tumors,,metastatic liver tumor count by size,,3.3,,1.5,4.7434,MMO:0000514,ex vivo caliper method,,0.0,,S4MH injection,21,days,S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days),108154,S4MH cells (250 X 10E3) (for 21 days),,,sham surgical control condition (for 11 days),,,, 3119,"Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2.",liver integrity trait,,RS:0002249,WAG/RijCrl,male,87 days,10,,CMO:0003610,metastatic liver tumor number,,metastatic liver tumor count by size,,9.3,,2.5,7.9057,MMO:0000514,ex vivo caliper method,,0.0,,S4MH injection,21,days,S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days),108155,S4MH cells (250 X 10E3) (for 21 days),,,sham surgical control condition (for 11 days),,,, 3119,"Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2.",lung mass,,RS:0002249,WAG/RijCrl,male,87 days,10,,CMO:0000097,lung wet weight,,,,1.4,g,0.08,0.253,MMO:0000005,post excision weight measurement,,0.0,,S4MH injection,21,days,S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days),108160,S4MH cells (250 X 10E3) (for 21 days),,,sham surgical control condition (for 11 days),,,, 3119,"Garc?a-Alonso I, et al., J Surg Res. 2008 Aug;148(2):185-90. doi: 10.1016/j.jss.2007.06.026. Epub 2007 Aug 2.",lung integrity trait,,RS:0002249,WAG/RijCrl,male,87 days,10,,CMO:0003434,metastatic lung tumor number,,,,28.5,,7.68,24.2863,MMO:0000162,ex vivo visual assessment,,0.0,,S4MH injection,21,days,S4MH cells (250 X 10E3) (for 21 days) then sham surgical control condition (for 11 days),108162,S4MH cells (250 X 10E3) (for 21 days),,,sham surgical control condition (for 11 days),,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",body mass,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000012,body weight,,,,482,g,11.0,34.7851,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition,108787,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",body mass,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000012,body weight,,,,340,g,9.0,27.0,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition,108788,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",eating behavior trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000427,food intake rate,,,,11,g/d,2.0,6.3246,MMO:0000620,food intake measuring method,,0.0,,,,,sham surgical control condition,108790,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",eating behavior trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000427,food intake rate,,,,13,g/d,1.0,3.0,MMO:0000620,food intake measuring method,,0.0,,,,,sham surgical control condition,108792,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",drinking behavior trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000741,water drink intake rate,,,,21,ml/d,1.0,3.1623,MMO:0000697,metabolic cage water drinking measurement method,,0.0,,,,,sham surgical control condition,108794,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",drinking behavior trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000741,water drink intake rate,,,,22,ml/d,1.0,3.0,MMO:0000697,metabolic cage water drinking measurement method,,0.0,,,,,sham surgical control condition,108795,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",urine output,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000260,timed urine volume,,,,15,ml/d,2.0,6.3246,MMO:0000511,metabolic cage urine volume measurement method,,0.0,,,,,sham surgical control condition,108798,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",urine output,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000260,timed urine volume,,,,13,ml/d,1.0,3.0,MMO:0000511,metabolic cage urine volume measurement method,,0.0,,,,,sham surgical control condition,108800,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",erythrocyte quantity,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000037,hematocrit,,,,47.8,%,0.6,1.8974,MMO:0000214,hematocrit analysis,,0.0,,,,,sham surgical control condition,108802,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart pumping trait,,RS:0000593,MWF/Hsd,male,84 days,5,,CMO:0000002,heart rate,,,,364,beats/min,14.0,31.305,MMO:0000011,vascular indwelling catheter method,heart,0.0,,,,,sham surgical control condition,108779,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",erythrocyte quantity,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000037,hematocrit,,,,45,%,0.8,2.4,MMO:0000214,hematocrit analysis,,0.0,,,,,sham surgical control condition,108804,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood sodium amount,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000060,plasma sodium level,,,,137,mmol/l,1.0,3.1623,MMO:0000037,automated blood electrolyte analysis,,0.0,,,,,sham surgical control condition,108806,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood sodium amount,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000060,plasma sodium level,,,,137,mmol/l,0.0,0.0,MMO:0000037,automated blood electrolyte analysis,,0.0,,,,,sham surgical control condition,108808,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood potassium amount,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000061,plasma potassium level,,,,4.4,mmol/l,0.2,0.6325,MMO:0000037,automated blood electrolyte analysis,,0.0,,,,,sham surgical control condition,108810,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood potassium amount,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000061,plasma potassium level,,,,4.5,mmol/l,0.1,0.3,MMO:0000037,automated blood electrolyte analysis,,0.0,,,,,sham surgical control condition,108812,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood chloride amount,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000059,plasma chloride level,,,,102,mmol/l,1.0,3.1623,MMO:0000037,automated blood electrolyte analysis,,0.0,,,,,sham surgical control condition,108814,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",blood chloride amount,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000059,plasma chloride level,,,,105,mmol/l,1.0,3.0,MMO:0000037,automated blood electrolyte analysis,,0.0,,,,,sham surgical control condition,108816,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",urine sodium amount,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000129,urine sodium level,,,,92,mmol/l,17.0,53.7587,MMO:0000456,automated urine sodium analysis,,0.0,,,,,sham surgical control condition,108818,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",urine sodium amount,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000129,urine sodium level,,,,147,mmol/l,11.0,33.0,MMO:0000456,automated urine sodium analysis,,0.0,,,,,sham surgical control condition,108820,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",urine potassium amount,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000128,urine potassium level,,,,115,mmol/l,15.0,47.4342,MMO:0000435,urine potassium analysis,,0.0,,,,,sham surgical control condition,108822,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",urine potassium amount,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000128,urine potassium level,,,,153,mmol/l,9.0,27.0,MMO:0000435,urine potassium analysis,,0.0,,,,,sham surgical control condition,108824,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",kidney mass,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0001953,right kidney wet weight to body weight ratio,,,,3.7,mg/g,0.1,0.3162,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition,108830,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",kidney mass,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0001953,right kidney wet weight to body weight ratio,,,,3.3,mg/g,0.1,0.3,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition,108832,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0000007,left ventricular systolic blood pressure,,,,128,mmHg,4.0,12.6491,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108846,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0000007,left ventricular systolic blood pressure,,,,134,mmHg,3.0,9.0,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108848,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,9091,mmHg/s,299.0,945.521,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108850,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0001745,maximum rate of positive change in left ventricular blood pressure,,,,8993,mmHg/s,318.0,954.0,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108852,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,7463,mmHg/s,375.0,1185.8541,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108854,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",heart left ventricular blood pressure trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0001746,maximum rate of negative change in left ventricular blood pressure,,,,6199,mmHg/s,513.0,1539.0,MMO:0000011,vascular indwelling catheter method,heart left ventricle,0.0,,,,,sham surgical control condition,108856,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0001955,renal blood flow rate to kidney weight ratio,,,,7.1,ml/min/g,0.8,2.5298,MMO:0000317,flowmetry,renal artery,0.0,,,,,sham surgical control condition,108858,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0001955,renal blood flow rate to kidney weight ratio,,,,2.8,ml/min/g,0.7,2.1,MMO:0000317,flowmetry,renal artery,0.0,,,,,sham surgical control condition,108860,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0004793,HsdCpb:WU,male,168 days,10,,CMO:0000220,systemic vascular resistance,,,,0.71,mmHg/ml/min,0.07,0.2214,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,108890,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0000593,MWF/Hsd,male,168 days,9,,CMO:0000220,systemic vascular resistance,,,,0.81,mmHg/ml/min,0.07,0.21,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,108892,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0004793,HsdCpb:WU,male,175 days,10,,CMO:0001898,renal vascular resistance,,,,13.2,mmHg/ml/min,1.9,6.0083,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,108894,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0000593,MWF/Hsd,male,175 days,9,,CMO:0001898,renal vascular resistance,,,,52.8,mmHg/ml/min,13.1,39.3,MMO:0000011,vascular indwelling catheter method,,0.0,,,,,sham surgical control condition,108895,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",cardiomyocyte morphology trait,,RS:0000593,MWF/Hsd,male,84 days,5,,CMO:0003840,cardiac myocyte cross-sectional area,,cardiac myocyte cross-sectional area (CMO:0003840),,535,um2,71.0,158.7608,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,heart left ventricle,0.0,,,,,sham surgical control condition,108900,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",cardiomyocyte morphology trait,,RS:0004793,HsdCpb:WU,male,84 days,5,,CMO:0003840,cardiac myocyte cross-sectional area,,cardiac myocyte cross-sectional area (CMO:0003840),,414,um2,48.0,107.3313,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,heart left ventricle,0.0,,,,,sham surgical control condition,108901,sham surgical control condition,,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",kidney glomerulus quantity,,RS:0000596,MWF/FubRkb,not specified,84 days,8,,CMO:0003674,kidney glomerular density,,,,7.3,/mm3,1.6,4.5255,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,,,,sham surgical control condition (for 84 days),109643,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",kidney glomerulus quantity,,RS:0004793,HsdCpb:WU,not specified,84 days,8,,CMO:0003674,kidney glomerular density,,,,12.1,/mm3,3.1,8.7681,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,,,,sham surgical control condition (for 84 days),109644,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",glomerular filtration trait,,RS:0004793,HsdCpb:WU,not specified,84 days,15,,CMO:0000765,creatinine clearance,,,,2.76,ml/min,0.17,0.6584,MMO:0000275,urine creatinine analysis,,0.0,,,,,sham surgical control condition (for 84 days),109645,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",glomerular filtration trait,,RS:0000596,MWF/FubRkb,not specified,84 days,15,,CMO:0000765,creatinine clearance,,,,2.36,ml/min,0.14,0.5422,MMO:0000275,urine creatinine analysis,,0.0,,,,,sham surgical control condition (for 84 days),109646,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",total urine protein amount,,RS:0004793,HsdCpb:WU,not specified,84 days,15,,CMO:0000756,urine total protein excretion rate,,,,8,mg/d,7.0,27.1109,MMO:0000335,urine total protein analysis,,0.0,,,,,sham surgical control condition (for 84 days),109651,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",total urine protein amount,,RS:0000596,MWF/FubRkb,not specified,84 days,15,,CMO:0000756,urine total protein excretion rate,,,,79.1,mg/d,9.5,36.7933,MMO:0000335,urine total protein analysis,,0.0,,,,,sham surgical control condition (for 84 days),109652,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",urine albumin amount,,RS:0004793,HsdCpb:WU,not specified,84 days,15,,CMO:0000757,urine albumin excretion rate,,,,0.2,mg/d,0.0,0.0,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 84 days),109658,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",urine albumin amount,,RS:0000596,MWF/FubRkb,not specified,84 days,15,,CMO:0000757,urine albumin excretion rate,,,,58.1,mg/d,5.8,22.4633,MMO:0000075,enzyme linked immunosorbent assay,,0.0,,,,,sham surgical control condition (for 84 days),109659,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",heart left ventricle integrity trait,,RS:0004793,HsdCpb:WU,not specified,86 days,15,,CMO:0003745,heart left ventricle interstitial fibrotic lesion area to total heart left ventricule area ratio,,,,3.6,%,0.6,2.3238,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,heart left ventricle,0.0,,,,,sham surgical control condition (for 84 days),109664,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",heart left ventricle integrity trait,,RS:0000596,MWF/FubRkb,not specified,86 days,15,,CMO:0003745,heart left ventricle interstitial fibrotic lesion area to total heart left ventricule area ratio,,,,1.6,%,0.2,0.7746,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,heart left ventricle,0.0,,,,,sham surgical control condition (for 84 days),109665,sham surgical control condition (for 84 days),,,,,,, 3035,"Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.",body mass,,RS:0000679,SBN/Ygl,male,16 days,8,,CMO:0000012,body weight,,n=8-15,,328,g,5.4,15.2735,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days),106640,sham surgical control condition (for 56 days),water (for 56 days),standard rat chow (for 56 days),,,,, 3035,"Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.",body mass,,RS:0000677,SBH/Ygl,male,16 days,8,,CMO:0000012,body weight,,n=8-15,,359,g,3.1,8.7681,MMO:0000016,body weighing method,,0.0,,,,,sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days),106643,sham surgical control condition (for 56 days),water (for 56 days),standard rat chow (for 56 days),,,,, 3035,"Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.",kidney mass,,RS:0000679,SBN/Ygl,male,16 days,8,,CMO:0000340,both kidneys wet weight to body weight ratio,,n=8-15,,2.4,g/kg,0.03,0.0849,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days),106646,sham surgical control condition (for 56 days),water (for 56 days),standard rat chow (for 56 days),,,,, 3035,"Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x.",kidney mass,,RS:0000677,SBH/Ygl,male,16 days,8,,CMO:0000340,both kidneys wet weight to body weight ratio,,n=8-15,,2.6,g/kg,0.07,0.198,MMO:0000005,post excision weight measurement,,0.0,,,,,sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days),106649,sham surgical control condition (for 56 days),water (for 56 days),standard rat chow (for 56 days),,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0004793,HsdCpb:WU,male,84 days,5,,CMO:0000009,mean arterial blood pressure,,,,89,mmHg,4.0,8.9443,MMO:0000011,vascular indwelling catheter method,aorta,0.0,,,,,sham surgical control condition,108772,sham surgical control condition,,,,,,, 3130,"Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19.",arterial blood pressure trait,,RS:0000593,MWF/Hsd,male,84 days,5,,CMO:0000009,mean arterial blood pressure,,,,102,mmHg,3.0,6.7082,MMO:0000011,vascular indwelling catheter method,aorta,0.0,,,,,sham surgical control condition,108773,sham surgical control condition,,,,,,, 3191,"Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7.",liver integrity trait,,RS:0001792,BDIX/OrlCrl,male,0 days,12,,CMO:0003757,increase in liver tumorous lesion volume between two points in time,,sham surgical group POD17,,0.56,cm3,0.13,0.4503,MMO:0000019,magnetic resonance imaging,liver,0.0,17-24 days after tumor cell injection,,,,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 17 days),110992,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days),DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days),,sham surgical control condition (0 %) (for 17 days),,,, 3183,"Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22.",blood glucose amount,,RS:0001317,GK/MolTac,male,252 days,9,,CMO:0003519,serum amylase activity level,,,,2164,U/l,29.0,87.0,MMO:0000554,automated serum analysis,,0.0,,,91,days,sham surgical control condition (for 126 days) then pantoprazole (100 umol/kg) (for 112 days) and sodium bicarbonate (8.5 %) (for 112 days),110761,sham surgical control condition (for 126 days),,,pantoprazole (100 umol/kg) (for 112 days),sodium bicarbonate (8.5 %) (for 112 days),,, 3183,"Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22.",blood glucose amount,,RS:0001317,GK/MolTac,male,252 days,9,,CMO:0003519,serum amylase activity level,,,,2265,U/l,40.0,120.0,MMO:0000554,automated serum analysis,,0.0,,,105,days,sham surgical control condition (for 126 days) then sodium bicarbonate (8.4 %) (for 112 days),110763,sham surgical control condition (for 126 days),,,sodium bicarbonate (8.4 %) (for 112 days),,,, 3191,"Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7.",liver integrity trait,,RS:0001792,BDIX/OrlCrl,male,0 days,12,,CMO:0003757,increase in liver tumorous lesion volume between two points in time,,sham surgical group POD24,,2.3,cm3,0.74,2.5634,MMO:0000019,magnetic resonance imaging,liver,0.0,17-31 days after tumor cell injection,,,,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (between 17 and 31 days),110996,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days),DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days),,sham surgical control condition (0 %) (between 17 and 31 days),,,, 3191,"Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7.",liver integrity trait,,RS:0001792,BDIX/OrlCrl,male,0 days,12,,CMO:0003758,subsequent liver tumorous lesion volume to precedent liver tumorous lesion volume ratio,,sham surgical group POD17,,518,%,117.0,405.2999,MMO:0000019,magnetic resonance imaging,liver,0.0,17-24 days after tumor cell injection,,,,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 17 days),111000,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days),DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days),,sham surgical control condition (0 %) (for 17 days),,,, 3191,"Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7.",liver integrity trait,,RS:0001792,BDIX/OrlCrl,male,0 days,12,,CMO:0003758,subsequent liver tumorous lesion volume to precedent liver tumorous lesion volume ratio,,sham surgical group POD24,,2112,%,618.0,2140.8148,MMO:0000019,magnetic resonance imaging,liver,0.0,17-31 days after tumor cell injection,,,,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 31 days),111001,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days),DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days),,sham surgical control condition (0 %) (for 31 days),,,, 3191,"Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7.",liver integrity trait,,RS:0001792,BDIX/OrlCrl,male,0 days,12,,CMO:0001080,calculated liver tumorous lesion volume measurement,,sham surgical group POD17,,0.67,cm3,0.13,0.4503,MMO:0000019,magnetic resonance imaging,liver,0.0,sham surgical group POD17,,24,days,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 17 days),110823,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days),DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days),,sham surgical control condition (0 %) (for 17 days),,,, 3191,"Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7.",liver integrity trait,,RS:0001792,BDIX/OrlCrl,male,0 days,12,,CMO:0001421,ratio of proliferating cell nuclear antigen-positive cells to total liver tumorous lesion cells,,sham surgical group POD30,,56.5,%,7.2,24.9415,MMO:0000538,ex vivo light microscopy with immunohistochemistry,liver,0.0,sham surgical group POD30,,37,days,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (for 30 days),110819,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days),DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days),,sham surgical control condition (0 %) (for 30 days),,,, 3183,"Grong E, et al., J Endocrinol Invest. 2018 Jun;41(6):691-701. doi: 10.1007/s40618-017-0793-9. Epub 2017 Nov 22.",blood glucose amount,,RS:0001317,GK/MolTac,male,224 days,9,,CMO:0002786,blood hemoglobin A1c level,,,,5.5,%,0.3,0.9,MMO:0000295,blood hemoglobin analysis,,0.0,,sham surgery,105,days,sham surgical control condition (for 126 days) then sodium bicarbonate (8.4 %) (for 112 days),110760,sham surgical control condition (for 126 days),,,sodium bicarbonate (8.4 %) (for 112 days),,,, 3191,"Schwarz L, etal., HPB (Oxford). 2020 Oct;22(10):1480-1489. doi: 10.1016/j.hpb.2020.02.008. Epub 2020 Mar 7.",liver integrity trait,,RS:0001792,BDIX/OrlCrl,male,0 days,12,,CMO:0001080,calculated liver tumorous lesion volume measurement,,sham surgical group POD24,,2.41,cm3,0.74,2.5634,MMO:0000019,magnetic resonance imaging,liver,0.0,sham surgical group POD24,,31,days,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days) and DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days) then sham surgical control condition (0 %) (between 17 and 31 days),110988,DHD/K12/TRb cells (1.5 x 10E6 cells) (for 7 days),DHD/K12/TRb cells (1 x 10E6 cells) (for 7 days),,sham surgical control condition (0 %) (between 17 and 31 days),,,, 3107,"Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252.",iliac artery morphology trait,,RS:0000155,BN/SsNHsd,male,133 days to 119 days,11,,CMO:0003646,circular vessel area,,,,0.2828,mm2,0.0299,0.0992,MMO:0000220,ex vivo light microscopy with digital image analysis,,0.0,,,,,sham surgical control condition,110495,sham surgical control condition,,,,,,, 3107,"Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252.",iliac artery morphology trait,,RS:0000155,BN/SsNHsd,male,133 days to 119 days,11,,CMO:0003646,circular vessel area,,,,0.282,mm2,0.0298,0.0988,MMO:0000220,ex vivo light microscopy with digital image analysis,,0.0,,,,,sham surgical control condition,110497,sham surgical control condition,,,,,,, 3107,"Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252.",iliac artery morphology trait,,RS:0000754,SHR/NHsd,male,133 days to 119 days,12,,CMO:0003646,circular vessel area,,,,0.3443,mm2,0.0227,0.0786,MMO:0000220,ex vivo light microscopy with digital image analysis,,0.0,,,,,sham surgical control condition,110498,sham surgical control condition,,,,,,, 3107,"Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252.",iliac artery morphology trait,,RS:0000754,SHR/NHsd,male,133 days to 119 days,12,,CMO:0001409,artery lumen area,,,,0.3443,mm2,0.225,0.7794,MMO:0000220,ex vivo light microscopy with digital image analysis,,0.0,,,,,sham surgical control condition,110500,sham surgical control condition,,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",heart left ventricle integrity trait,,RS:0004793,HsdCpb:WU,not specified,86 days,15,,CMO:0003746,heart left ventricle perivascular fibrotic lesion area to total heart left ventricule area ratio,,,,10,%,1.2,4.6476,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,heart left ventricle,0.0,,,,,sham surgical control condition (for 84 days),109670,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",heart left ventricle integrity trait,,RS:0000596,MWF/FubRkb,not specified,86 days,15,,CMO:0003746,heart left ventricle perivascular fibrotic lesion area to total heart left ventricule area ratio,,,,4.5,%,0.3,1.1619,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,heart left ventricle,0.0,,,,,sham surgical control condition (for 84 days),109671,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",kidney integrity trait,,RS:0004793,HsdCpb:WU,not specified,86 days,15,,CMO:0003747,kidney interstitial fibrotic lesion area to total kidney area ratio,,,,4.2,%,0.1,0.3873,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,,,,sham surgical control condition (for 84 days),109676,sham surgical control condition (for 84 days),,,,,,, 3149,"Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23.",kidney integrity trait,,RS:0000596,MWF/FubRkb,not specified,86 days,15,,CMO:0003747,kidney interstitial fibrotic lesion area to total kidney area ratio,,,,5,%,0.4,1.5492,MMO:0000560,ex vivo light microscopy with histochemistry and digital image analysis,,0.0,,,,,sham surgical control condition (for 84 days),109677,sham surgical control condition (for 84 days),,,,,,,