Study ID,Study,Experiment Name,Experiment Notes,Strain Ont ID,Strain,Sex,Age,# of Animals,Sample Notes,Clinical Measurement Ont ID,Phenotype,Formula,Clinical Measurement Notes,Average Type,Value,Units,SEM,SD,Method Ont ID,Method,Method Site,Method Duration,Method Notes,Post Insult Type,Post Insult Time Value,Post Insult Time Unit,Conditions,Record ID,Condition 1a,Condition 1b,Condition 2a,Condition 2b,Condition 3a,Condition 3b 482,PhysGen Renal B data,urine sodium amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,6,,CMO:0000760,urine sodium excretion rate,,,,23.1445,mEq/d,3.4391,8.4241,MMO:0000039,flame atomic emission spectrometry,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52788,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,urine sodium amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,7,,CMO:0000760,urine sodium excretion rate,,,,30.4837,mEq/d,3.7038,9.7993,MMO:0000039,flame atomic emission spectrometry,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52804,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,renin activity,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,5,,CMO:0000116,plasma renin activity level,,,,4.346,ng/ml/h,1.3243,2.9613,MMO:0000073,radioimmunoassay,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52886,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,renin activity,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,7,,CMO:0000116,plasma renin activity level,,,,2.1886,ng/ml/h,0.6927,1.8327,MMO:0000073,radioimmunoassay,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52902,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,total urine protein amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,6,,CMO:0000756,urine total protein excretion rate,,,,120.2125,mg/d,42.954,105.2155,MMO:0000359,automated urine total protein analysis,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52102,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,total urine protein amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,8,,CMO:0000756,urine total protein excretion rate,,,,260.8312,mg/d,72.1097,203.9571,MMO:0000359,automated urine total protein analysis,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52118,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,blood creatinine amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,4,,CMO:0000537,plasma creatinine level,,,,0.4888,mg/dl,0.0457,0.0914,MMO:0000073,radioimmunoassay,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52251,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,blood creatinine amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,8,,CMO:0000537,plasma creatinine level,,,,0.43,mg/dl,0.0221,0.0624,MMO:0000073,radioimmunoassay,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52267,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,urine potassium amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,6,,CMO:0000761,urine potassium excretion rate,,,,1.9985,mEq/d,0.3067,0.7512,MMO:0000039,flame atomic emission spectrometry,,,urine potassium analysis,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52300,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,urine potassium amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,8,,CMO:0000761,urine potassium excretion rate,,,,2.6739,mEq/d,0.7857,2.2224,MMO:0000039,flame atomic emission spectrometry,,,urine potassium analysis,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52316,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,glomerular filtration trait,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,4,,CMO:0000765,creatinine clearance,,,,1.0908,ml/min,0.1041,0.2082,MMO:0000275,urine creatinine analysis,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52347,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,glomerular filtration trait,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,8,,CMO:0000765,creatinine clearance,,,,1.5531,ml/min,0.1604,0.4538,MMO:0000275,urine creatinine analysis,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52363,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,urine albumin amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,6,,CMO:0000757,urine albumin excretion rate,,,,66.4865,mg/d,34.2178,83.816,MMO:0000073,radioimmunoassay,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52394,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,urine albumin amount,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,8,,CMO:0000757,urine albumin excretion rate,,,,139.1481,mg/d,34.3411,97.1314,MMO:0000073,radioimmunoassay,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52410,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,heart pumping trait,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,6,,CMO:0000002,heart rate,,,,424.872,beats/min,7.2372,17.7274,MMO:0000013,vascular fluid filled catheter,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52492,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,heart pumping trait,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,8,,CMO:0000002,heart rate,,,,405.6248,beats/min,14.938,42.251,MMO:0000013,vascular fluid filled catheter,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52508,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,arterial blood pressure trait,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,female,99 days to 80 days,6,,CMO:0000009,mean arterial blood pressure,,,,156.0315,mmHg,5.1123,12.5226,MMO:0000013,vascular fluid filled catheter,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52539,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 482,PhysGen Renal B data,arterial blood pressure trait,"Moms were fed Teklad, pups used in studies were fed Dyets",RS:0000323,FHH-Chr 14BN/Mcwi,male,99 days to 80 days,8,,CMO:0000009,mean arterial blood pressure,,,,164.5386,mmHg,7.8591,22.2289,MMO:0000013,vascular fluid filled catheter,,,,,,,controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),52555,controlled sodium content diet (8 %) (between 19 and 22 days),controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days),,,, 522,PhysGen Vascular data,vasodilation trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,female,84 days to 70 days,10,,CMO:0000724,concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,1.7558,E-7mole,0.3735,1.1812,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56497,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours) 522,PhysGen Vascular data,vasodilation trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,male,84 days to 70 days,9,,CMO:0000724,concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,1.7357,E-7mole,0.6585,1.9756,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56513,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours) 522,PhysGen Vascular data,vasodilation trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,female,84 days to 70 days,10,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,78,%,13.3242,42.1347,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),54757,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours) 522,PhysGen Vascular data,vasodilation trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,male,84 days to 70 days,9,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,81.7778,%,4.355,13.065,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),54773,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours) 522,PhysGen Vascular data,vasoconstriction trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,female,84 days to 70 days,10,,CMO:0000728,maximum contractile force per wet weight of aorta,,,,1,g/mg,0.155,0.4902,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours),57311,controlled sodium content diet (4 %) (for 21 days),,potassium ion (80 mmol/l) (for 0.2 hours),phenylephrine (10 umol/l) (for 0.2 hours),, 522,PhysGen Vascular data,vasoconstriction trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,male,84 days to 70 days,10,,CMO:0000728,maximum contractile force per wet weight of aorta,,,,1.175,g/mg,0.1238,0.3915,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours),57327,controlled sodium content diet (4 %) (for 21 days),,potassium ion (80 mmol/l) (for 0.2 hours),phenylephrine (10 umol/l) (for 0.2 hours),, 522,PhysGen Vascular data,vasoconstriction trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,female,84 days to 70 days,10,,CMO:0000721,concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50),,,,0.0139,umol/l,0.0029,0.0092,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),54883,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),, 522,PhysGen Vascular data,vasodilation trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,female,84 days to 70 days,10,,CMO:0000725,logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-6.834,,0.0865,0.2735,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56892,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours) 522,PhysGen Vascular data,vasodilation trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,male,84 days to 70 days,9,,CMO:0000725,logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-6.9232,,0.1317,0.3952,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56908,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours) 522,PhysGen Vascular data,vasoconstriction trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,male,84 days to 70 days,9,,CMO:0000721,concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50),,,,0.0207,umol/l,0.0033,0.01,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),54899,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),, 522,PhysGen Vascular data,vasoconstriction trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,female,84 days to 70 days,10,,CMO:0000722,logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50),,EC50 value is moles/liter,,-7.9883,,0.1288,0.4074,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),56082,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),, 522,PhysGen Vascular data,vasoconstriction trait,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,male,84 days to 70 days,9,,CMO:0000722,logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50),,EC50 value is moles/liter,,-7.7181,,0.0585,0.1756,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),56098,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),, 522,PhysGen Vascular data,body mass,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,female,84 days to 70 days,10,,CMO:0000012,body weight,,,,144.4,g,7.2,22.7,MMO:0000017,whole body digital scale,,,,,,,controlled sodium content diet (4 %) (for 21 days),55162,controlled sodium content diet (4 %) (for 21 days),,,,, 522,PhysGen Vascular data,body mass,Moms and pups used in studies were fed Teklad,RS:0000323,FHH-Chr 14BN/Mcwi,male,84 days to 70 days,10,,CMO:0000012,body weight,,,,168.7,g,5.4,17.2,MMO:0000017,whole body digital scale,,,,,,,controlled sodium content diet (4 %) (for 21 days),55176,controlled sodium content diet (4 %) (for 21 days),,,,,