Study ID,Study,Experiment Name,Experiment Notes,Strain Ont ID,Strain,Sex,Age,# of Animals,Sample Notes,Clinical Measurement Ont ID,Phenotype,Formula,Clinical Measurement Notes,Average Type,Value,Units,SEM,SD,Method Ont ID,Method,Method Site,Method Duration,Method Notes,Post Insult Type,Post Insult Time Value,Post Insult Time Unit,Conditions,Record ID,Condition 1a,Condition 1b,Condition 2a,Condition 2b,Condition 3a,Condition 3b,Condition 4,Condition 5,Condition 6 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,17,,CMO:0000727,logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-8.2469,,0.1703,0.7023,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),55701,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000727,logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-8.9057,,0.0516,0.1933,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),55702,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,16,,CMO:0000727,logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-7.5445,,0.0647,0.2589,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),55246,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,16,,CMO:0000727,logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-7.4933,,0.0539,0.2155,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),55247,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,16,,CMO:0000728,maximum contractile force per wet weight of aorta,,,,1.3663,g/mg,0.2309,0.9235,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours),57114,controlled sodium content diet (4 %) (for 21 days),,potassium ion (80 mmol/l) (for 0.2 hours),phenylephrine (10 umol/l) (for 0.2 hours),,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,18,,CMO:0000728,maximum contractile force per wet weight of aorta,,,,1.3911,g/mg,0.1519,0.6446,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours),57115,controlled sodium content diet (4 %) (for 21 days),,potassium ion (80 mmol/l) (for 0.2 hours),phenylephrine (10 umol/l) (for 0.2 hours),,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,20,,CMO:0000728,maximum contractile force per wet weight of aorta,,,,0.9487,g/mg,0.0932,0.4166,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours),56066,potassium ion (80 mmol/l) (for 0.2 hours),phenylephrine (10 umol/l) (for 0.2 hours),,,,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,23,,CMO:0000728,maximum contractile force per wet weight of aorta,,,,1.0109,g/mg,0.0539,0.2586,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours),56067,potassium ion (80 mmol/l) (for 0.2 hours),phenylephrine (10 umol/l) (for 0.2 hours),,,,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,14,,CMO:0000724,concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,1.2875,E-7mole,0.1927,0.721,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56725,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,19,,CMO:0000724,concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,0.8343,E-7mole,0.1735,0.7564,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56726,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,10,,CMO:0000724,concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,2.9675,E-7mole,0.7065,2.2343,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56211,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000724,concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,1.6961,E-7mole,0.6149,2.3008,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56212,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,14,,CMO:0000722,logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50),,EC50 value is moles/liter,,-7.211,,0.1132,0.4237,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),57305,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,19,,CMO:0000722,logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50),,EC50 value is moles/liter,,-6.9574,,0.1068,0.4654,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),57306,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,13,,CMO:0000722,logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50),,EC50 value is moles/liter,,-7.3343,,0.1065,0.3838,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),56491,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000722,logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50),,EC50 value is moles/liter,,-7.4916,,0.0852,0.3189,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),56492,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,14,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,82.2857,%,3.5183,13.1642,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56806,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,19,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,84.6316,%,3.6724,16.0077,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56807,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,10,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,69,%,6.6933,21.166,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),55730,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000731,acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,85.5,%,4.8593,18.1818,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),55731,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,10,,CMO:0000725,logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-6.6198,,0.0909,0.2874,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),57193,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000725,logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-6.9777,,0.1061,0.3969,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),57194,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,14,,CMO:0000725,logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-6.9543,,0.0659,0.2466,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56225,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,19,,CMO:0000725,logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50),,,,-7.1897,,0.0681,0.2966,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours),56226,phenylephrine (1 umol/l) (for 0.2 hours),,acetylcholine (0-30 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,15,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,65.4847,%,5.8461,22.6417,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours),56782,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours) 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,13,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,61.1708,%,5.7829,20.8506,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours),56783,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours) 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,15,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,46.276,%,5.648,21.8744,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),56886,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours), 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,13,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,48.4046,%,6.9847,25.1838,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),56887,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours), 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,12,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,63.0575,%,7.2913,25.2578,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours),56760,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),,controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours), 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,12,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,63.3517,%,6.5336,22.6331,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours),56761,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),,controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),controlled oxygen content physiological salt solution perfusate (0 %) (for 0.3 hours), 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,12,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,50.1675,%,9.8883,34.254,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),56256,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),,controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,12,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,57.7583,%,6.6078,22.8901,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours) then controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),56257,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),,controlled oxygen content physiological salt solution perfusate (5 %) (for 0.3 hours),, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,15,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,36.5173,%,3.8654,14.9707,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),54635,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,13,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,40.7069,%,5.2121,18.7925,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),54636,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,12,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,47.26,%,9.3165,32.2732,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),55007,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,12,,CMO:0000733,hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,50.1325,%,5.5788,19.3254,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) then controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours) then controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),55008,phenylephrine (1 umol/l) ,,controlled oxygen content physiological salt solution perfusate (95 %) (for 0.2 hours),,controlled oxygen content physiological salt solution perfusate (10 %) (for 0.3 hours),,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,17,,CMO:0000732,sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,99.4706,%,0.4211,1.7363,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),57293,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000732,sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,99.7857,%,0.1547,0.5789,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),57294,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,16,,CMO:0000732,sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,100,%,0.0,0.0,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),57447,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,16,,CMO:0000732,sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel,,,,99.625,%,0.1797,0.7188,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),57448,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,17,,CMO:0000726,concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,0.1728,10E-7mol/l,0.0535,0.2206,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),56013,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000726,concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,0.0135,10E-7mol/l,0.0018,0.0066,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),56014,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,,,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,16,,CMO:0000726,concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,0.3333,10E-7mol/l,0.0477,0.1907,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),55502,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasodilation trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,16,,CMO:0000726,concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50),,,,0.366,10E-7mol/l,0.0566,0.2264,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours),55503,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (1 umol/l) (for 0.2 hours),,sodium nitroprusside (0-3 umol/l) ,drug dose time series (for 1 hours),,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,14,,CMO:0000721,concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50),,,,0.0932,umol/l,0.0226,0.0846,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),56835,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,19,,CMO:0000721,concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50),,,,0.2491,umol/l,0.1275,0.5556,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),56836,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,male,84 days to 70 days,13,,CMO:0000721,concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50),,,,0.0641,umol/l,0.015,0.0541,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),57195,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,, 522,PhysGen Vascular data,vasoconstriction trait,"Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan",RS:0000698,Hsd:SD,female,84 days to 70 days,14,,CMO:0000721,concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50),,,,0.0406,umol/l,0.0076,0.0283,MMO:0000208,wire myography using a Digi-Med tissue force analysis system with force transducer,,,,,,,controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours),57196,controlled sodium content diet (4 %) (for 21 days),,phenylephrine (0-300 umol/l) ,drug dose time series (for 1.2 hours),,,,,