ADRENERGIC BETA RECEPTOR AGONIST AND BETA-BLOCKER PHARMACODYNAMICS PATHWAY (PW:0000801)

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Description

Norepinephrine and epinephrine, whose synthesis and release are prompted by various but distinct stresses, act as neurotransmitters and hormones that signal via the various adrenergic receptors, G-protein-coupled receptors (GPCR) that couple to distinct G alpha subunits of heterotrimeric G proteins. The beta receptors, for which epinephrine appears to be a favorite agonist, couple to the Gs alpha subunit, leading to activation of adenylyl cyclases, cAMP production, and subsequent triggering of t

Pathway Diagram:

Ariadne Genomics Inc. epinephrine signaling pathway via adrenergic receptor beta beta-blockers beta agonists, long-acting beta agonists, short-acting beta-blockers ---> Adrb1 beta-blockers ---> Adrb2 Adrb1 Adrb2 Adrb2 ---> Heart Failure Adrb1 ---> Heart Failure Adrb2 ---> Asthma beta agonists, long-acting ---> Adrb2 beta agonists, short-acting ---> Adrb2 Heart Failure Asthma
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Genes in Pathway:

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adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc8 ATP binding cassette subfamily C member 8 JBrowse link 1 102,110,708 102,191,287 RGD:10402751
G Abcc9 ATP binding cassette subfamily C member 9 JBrowse link 4 176,806,098 176,928,540 RGD:10402751
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:4140443
RGD:10402751
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:4140443
RGD:4140444
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:10402751
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:10402751
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:10402751
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 JBrowse link 1 81,852,423 81,881,565 RGD:10402751
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 JBrowse link 13 90,605,792 90,642,032 RGD:10402751
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 JBrowse link 13 82,737,161 82,757,681 RGD:10402751
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 JBrowse link 10 56,205,622 56,211,879 RGD:10402751
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 JBrowse link 8 104,190,032 104,221,342 RGD:10402751
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 JBrowse link X 124,631,544 124,652,520 RGD:10402751
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:10402751
G Cacna1c calcium voltage-gated channel subunit alpha1 C JBrowse link 4 150,635,808 151,270,790 RGD:10402751
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:10402751
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:10402751
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 JBrowse link 8 116,154,661 116,285,643 RGD:10402751
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 JBrowse link 10 85,954,138 85,974,764 RGD:10402751
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:10402751
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:10402751
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:10402751
G Fxyd2 FXYD domain-containing ion transport regulator 2 JBrowse link 8 49,710,334 49,717,492 RGD:10402751
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 JBrowse link 8 63,599,907 63,637,327 RGD:10402751
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 JBrowse link 4 140,247,297 140,580,749 RGD:10402751
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:10402751
G Kcnd3 potassium voltage-gated channel subfamily D member 3 JBrowse link 2 207,923,775 208,140,727 RGD:10402751
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:10402751
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 JBrowse link 11 32,434,786 32,447,264 RGD:10402751
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:10402751
G Kcnip2 potassium voltage-gated channel interacting protein 2 JBrowse link 1 265,549,610 265,573,393 RGD:10402751
G Kcnj11 potassium voltage-gated channel subfamily J member 11 JBrowse link 1 102,103,093 102,107,134 RGD:10402751
G Kcnj2 potassium voltage-gated channel subfamily J member 2 JBrowse link 10 99,429,337 99,442,520 RGD:10402751
G Kcnj3 potassium voltage-gated channel subfamily J member 3 JBrowse link 3 41,019,898 41,181,070 RGD:10402751
G Kcnj4 potassium voltage-gated channel subfamily J member 4 JBrowse link 7 120,717,378 120,744,602 RGD:10402751
G Kcnj5 potassium voltage-gated channel subfamily J member 5 JBrowse link 8 33,435,493 33,463,410 RGD:10402751
G Kcnj8 potassium voltage-gated channel subfamily J member 8 JBrowse link 4 176,783,287 176,789,143 RGD:10402751
G Kcnk1 potassium two pore domain channel subfamily K member 1 JBrowse link 19 58,823,836 58,862,926 RGD:10402751
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:10402751
G Mylk myosin light chain kinase JBrowse link 11 69,013,060 69,260,039 RGD:10402751
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:10402751
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:10402751
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:10402751
G Prkar1a protein kinase cAMP-dependent type 1 regulatory subunit alpha JBrowse link 10 97,940,705 97,959,199 RGD:10402751
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:10402751
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:10402751
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:10402751
G Snta1 syntrophin, alpha 1 JBrowse link 3 149,874,023 149,905,980 RGD:10402751
G Sntb1 syntrophin, beta 1 JBrowse link 7 95,395,417 95,670,093 RGD:10402751
G Sntb2 syntrophin, beta 2 JBrowse link 19 39,126,589 39,209,152 RGD:10402751
G Tnnc1 troponin C1, slow skeletal and cardiac type JBrowse link 16 7,292,207 7,295,238 RGD:10402751
G Tnnc2 troponin C2, fast skeletal type JBrowse link 3 161,243,607 161,246,335 RGD:10402751
G Tnni1 troponin I1, slow skeletal type JBrowse link 13 52,624,856 52,637,297 RGD:10402751
G Tnni2 troponin I2, fast skeletal type JBrowse link 1 215,609,110 215,611,652 RGD:10402751
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:10402751
G Tnnt1 troponin T1, slow skeletal type JBrowse link 1 72,889,270 72,899,629 RGD:10402751
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:10402751
G Tnnt3 troponin T3, fast skeletal type JBrowse link 1 215,666,628 215,683,628 RGD:10402751
G Tpm1 tropomyosin 1 JBrowse link 8 72,814,737 72,841,496 RGD:10402751
G Tpm2 tropomyosin 2 JBrowse link 5 59,016,616 59,025,971 RGD:10402751

Additional Elements in Pathway:

(includes Gene Groups, Small Molecules, Other Pathways..etc.)
Object TypePathway ObjectPathway Object Description
Small Moleculebeta agonists, short acting
Small Moleculebeta blockers
Small Moleculebeta agonists, long acting
Pathwayepinephrine signaling via adrenergic receptor
DiseaseHeart Failureentry point to the cardiovascular disease portal
DiseaseAsthmaentry point to the respiratory disease portal

Pathway Gene Annotations

Disease Annotations Associated with Genes in the adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway
Disease TermsGene Symbols
2-Aminoadipic 2-Oxoadipic AciduriaHcn4
abdominal aortic aneurysmAgtr1a , Mylk
abdominal obesity-metabolic syndrome 1Atp2a2
Abortion, SpontaneousAgtr1a
AchlorhydriaKcnq1
acrodysostosisPrkar1a
Acrodysostosis 1, with or without Hormone ResistancePrkar1a
acrokeratosis verruciformisAtp2a2
Acute Coronary SyndromeTnni3 , Tnnt2
acute kidney failureAdrb2
Acute Lung InjuryMylk
acute myeloid leukemiaAtp1b1 , Plcb1
acute promyelocytic leukemiaPrkar1a
adenocarcinomaKcnq1
adenomaAtp1a1 , Kcnj5
Adrenal Cortex NeoplasmsPrkar1a
adrenal cortical adenomaAtp1a1 , Prkaca
Adrenal Gland NeoplasmsPrkaca
adult respiratory distress syndromeMylk
AIDS Dementia ComplexAdrb2
AIDS-Associated NephropathyAgtr1a
Allanson Pantzar McLeod SyndromeAgtr1a
allergic hypersensitivity diseaseMylk
alternating hemiplegia of childhoodAtp1a2 , Atp1a3
Alternating Hemiplegia of Childhood 2Atp1a3
Alzheimer's diseaseAgtr1a , Cacna1c , Calm1 , Itpr1 , Plcb1 , Slc8a1
amelogenesis imperfecta type 1GPrkar1a
AnaphylaxisAdrb1
anauxetic dysplasia 1Tpm2
Andersen-Tawil syndromeKcnj2 , Kcnj5
Angina PectorisAdrb1 , Adrb2
anthracosisAtp1a4
anti-basement membrane glomerulonephritisAgtr1a
aortic aneurysmMylk
Aortic Aneurysm, Familial Abdominal 1Mylk
aortic valve stenosisAdrb1
apparent mineralocorticoid excess syndromePrkar1a
arrhythmogenic right ventricular cardiomyopathyAbcc9 , Hcn4 , Kcne1 , Kcnh2 , Pln , Ryr2 , Scn5a , Snta1
arrhythmogenic right ventricular dysplasia 1Ryr2
arrhythmogenic right ventricular dysplasia 2Ryr2
arrhythmogenic right ventricular dysplasia 9Pln , Ryr2
Arsenic PoisoningKcnj2
arteriovenous malformations of the brainCacna1h
ArthrogryposisTnni2 , Tnnt3 , Tpm2
asthmaAdrb2 , Agtr1a , Chrm2 , Itpr1 , Mylk
AtaxiaCacna2d2 , Itpr1
atrial fibrillationAbcc9 , Agtr1a , Hcn4 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnj2 , Kcnj5 , Kcnq1 , Pln , Scn5a
atrial heart septal defectAbcc8 , Mylk
atrial heart septal defect 1Tpm1
Atrial Myxoma, FamilialPrkar1a
Atrial StandstillScn5a
atrioventricular blockScn5a
autism spectrum disorderKcnj3 , Ryr2
autistic disorderAdrb2 , Atp1b4 , Cacna1c , Cacna1h , Dlg1 , Pln
autosomal recessive distal spinal muscular atrophy 2Tpm2
Becker muscular dystrophySnta1
Beckwith-Wiedemann syndromeKcnq1
benign epilepsy with centrotemporal spikesPlcb1
benign neonatal seizuresAtp1a2
bipolar disorderAtp1a3 , Cacna1c , Chrm2
Birth WeightAdrb1
BradycardiaChrm2
brain edemaAbcc8 , Mylk
Brain HypoxiaItpr1
Brain InjuriesAbcc8 , Chrm2
brain ischemiaPrkaca , Scn5a , Slc8a1
breast cancerAgtr1a
breast ductal carcinomaAbcc9 , Cacna1c , Cacna1h
Breast NeoplasmsAdrb2
bronchiolitisAdrb2
Brugada syndromeAbcc9 , Cacna1c , Hcn4 , Kcnd3 , Kcne1 , Kcnh2 , Kcnj8 , Kcnq1 , Scn5a , Snta1
Brugada syndrome 1Kcna5 , Kcnh2 , Kcnj8 , Ryr2 , Scn5a
Brugada syndrome 3Cacna1c
Brugada syndrome 8Hcn4
Brugada syndrome 9Kcnd3
Bundle-Branch BlockScn5a
Burn-Mckeown SyndromeKcnq1
CachexiaAtp2a2
candidiasisChrm2
cannabis abuseCalm1
CAPOS SyndromeAtp1a3
cardiac arrestAbcc8 , Hcn4 , Itpr1 , Kcnj8 , Pln , Ryr2 , Scn5a
Cardiac ArrhythmiasAgtr1a , Atp1b1 , Cacna1c , Cacna2d2 , Hcn4 , Kcna5 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj2 , Kcnj5 , Kcnj8 , Kcnq1 , Ryr2 , Scn5a , Snta1
Cardiac Complexes, PrematureCacna1c , Hcn4 , Kcne2 , Kcnh2 , Kcnj2 , Kcnq1 , Ryr2 , Scn5a , Snta1
Cardiac Conduction DefectRyr2
Cardiac Conduction Defect, NonprogressiveScn5a
Cardiac Conduction Defect, NonspecificScn5a
CardiomegalyAgtr1a , Atp1a2 , Atp2a2 , Kcnd3 , Slc8a1 , Tnnt2
cardiomyopathyAbcc9 , Adrb2 , Chrm2 , Pln , Ryr2 , Scn5a , Tnnc1 , Tnni3 , Tnnt1 , Tnnt2 , Tpm1
Cardiomyopathy, Familial Restrictive, 1Tnni3
Cardiomyopathy, Familial Restrictive, 3Tnnt2
cardiovascular system diseaseAdrb1 , Adrb2 , Tnnt2
Carney complexPrkar1a
carotid artery diseaseAgtr1a
carotid artery dissectionMylk
Carotid Artery Dissection, InternalMylk
Carotid Artery InjuriesAgtr1a
carotid artery occlusionMylk
catecholaminergic polymorphic ventricular tachycardiaCalm1 , Kcnh2 , Ryr2 , Scn5a , Tpm1
catecholaminergic polymorphic ventricular tachycardia 1Calm1 , Kcnh2 , Ryr2 , Scn5a , Tpm1
catecholaminergic polymorphic ventricular tachycardia 2Ryr2
catecholaminergic polymorphic ventricular tachycardia 4Calm1
Cell Transformation, NeoplasticKcnh2
central core myopathyRyr2
centronuclear myopathyPln
cerebrovascular diseaseAgtr1a
Chagas diseaseChrm2
Charcot-Marie-Tooth Disease, Axonal, Type 2DDAtp1a1
Chemical and Drug Induced Liver InjuryItpr1
childhood absence epilepsyCacna1h , Cacna2d2
Childhood SchizophreniaRyr2
cholangiocarcinomaAdrb2 , Prkaca
choreatic diseaseCacna2d2
chronic kidney diseaseAgtr1a
chronic obstructive pulmonary diseaseAdrb1 , Adrb2 , Tnnt2
Ciliary Motility DisordersTnni3 , Tnnt1
cleft palateDlg1
Cocaine-Related DisordersCalm1
Colonic NeoplasmsKcnh2 , Plcb1
Colorectal NeoplasmsAbcc8
congenital adrenal hyperplasiaPrkar1a
congenital fiber-type disproportionTpm2
congenital heart diseaseRyr2
Congenital HyperinsulinismAbcc8 , Kcnj11
Congenital Limb DeformitiesCacna1c
congenital myasthenic syndromeCacna1c
congenital myasthenic syndrome 10Cacna1c
congenital structural myopathyTpm2
congestive heart failureAdrb1 , Adrb2 , Agtr1a , Atp1a3 , Atp2a2 , Kcne1 , Pln , Prkaca , Ryr2 , Scn5a , Slc8a1 , Tnnt2
connective tissue diseaseMylk
corneal neovascularizationAgtr1a
coronary artery diseaseAbcc9 , Agtr1a , Kcnj8 , Tnni3
Coronary DiseaseAdrb2 , Agtr1a , Kcnj8
Costello syndromeTnnt2
Cushing syndromePrkar1a
cystic fibrosisAdrb1 , Adrb2
Danon diseaseAtp1b4
Darier Disease, Acral Hemorrhagic TypeAtp2a2
Darier Disease, SegmentalAtp2a2
DeafnessKcnk1 , Kcnq1
DeathScn5a
dermatitisAdrb2
Developmental Delay, Epilepsy, and Neonatal DiabetesKcnj11
Developmental DisabilitiesAtp1a3
Diabetes ComplicationsPln
diabetes mellitusAbcc8 , Adrb1 , Itpr1 , Kcnj11
Diabetes Mellitus, Experimental Abcc9 , Adrb1 , Atp2a2 , Chrm2 , Kcna5 , Kcne2 , Kcnj11 , Ryr2 , Slc8a1
Diabetic CardiomyopathiesAtp2a2 , Pln , Ryr2 , Slc8a1
Diabetic NephropathiesAgtr1a
diabetic neuropathyChrm2
diabetic retinopathyAgtr1a
Diaphragmatic HerniaAgtr1a
Diastolic DysfunctionRyr2
dilated cardiomyopathyAbcc9 , Adrb1 , Adrb2 , Agtr1a , Cacna1c , Chrm2 , Hcn4 , Itpr1 , Kcne2 , Kcnh2 , Pln , Ryr2 , Scn5a , Slc8a1 , Tnnc1 , Tnni3 , Tnnt1 , Tnnt2 , Tpm1
dilated cardiomyopathy 1AARyr2
dilated cardiomyopathy 1BBTnnt2
dilated cardiomyopathy 1DTnnt2
dilated cardiomyopathy 1DDTnnt2
dilated cardiomyopathy 1EScn5a
dilated cardiomyopathy 1FFTnni3
dilated cardiomyopathy 1OAbcc9
dilated cardiomyopathy 1PPln
dilated cardiomyopathy 1STnnc1 , Tnnt2
dilated cardiomyopathy 1YTpm1
dilated cardiomyopathy 1ZTnnc1
dilated cardiomyopathy 2ATnni3
Dilated Cardiomyopathy with Left Ventricular NoncompactionRyr2 , Scn5a , Tnnt2 , Tpm1
disease of cellular proliferationKcnh2
disease of metabolismAdrb2
distal arthrogryposisTnni2 , Tnnt3 , Tpm2
Distal Arthrogryposis Multiplex Congenita, Type 1Tpm2
Distal Arthrogryposis Type 2BTnni2 , Tnnt3 , Tpm2
Distal Arthrogryposis, Type 1ATpm2
Drug-Related Side Effects and Adverse ReactionsCacna1h
Duchenne muscular dystrophySnta1
Ductal CarcinomaAgtr1a
dystoniaAtp1a3
dystonia 12Atp1a3
early infantile epileptic encephalopathyCacna2d2
early infantile epileptic encephalopathy 1Plcb1
early infantile epileptic encephalopathy 12Plcb1
EAST syndromeAtp1a2
Ebstein anomalyPln
Ehlers-Danlos Syndrome Type 6Tnnt2
end stage renal failureAdrb2
Endometrial NeoplasmsAbcc9
endometriosisAbcc9
endomyocardial fibrosisAdrb1
EndotoxemiaAbcc8
epilepsyAtp1a3 , Cacna1c , Cacna2d2 , Chrm2 , Itpr1
Esophageal NeoplasmsTpm1
essential hypertensionAgtr1a , Atp1b1 , Atp2a2
euthyroid sick syndromeAtp2a2
Experimental Autoimmune MyocarditisKcna5
Experimental Liver CirrhosisAdrb1 , Adrb2 , Agtr1a , Fxyd2 , Kcnj8 , Tpm1
familial atrial fibrillationAbcc9 , Kcna5 , Kcne2 , Kcnj2 , Kcnq1 , Scn5a
Familial Atrial Fibrillation 10Scn5a
Familial Atrial Fibrillation 12Abcc9
Familial Atrial Fibrillation 3Kcnq1
Familial Atrial Fibrillation 4Kcne2
Familial Atrial Fibrillation 7Kcna5
Familial Atrial Fibrillation 9Kcnj2
Familial Basilar MigraineAtp1a2
familial hemiplegic migraineAtp1a2
Familial Hemiplegic Migraine, Type 2Atp1a2
Familial HyperaldosteronismKcnj5
Familial Hyperaldosteronism, Type IIIKcnj5
Familial Hyperaldosteronism, Type IVCacna1h
familial hyperinsulinemic hypoglycemia 1Abcc8
familial hyperinsulinemic hypoglycemia 2Abcc8 , Kcnj11
familial hyperlipidemiaAdrb2
familial hypertrophic cardiomyopathyAbcc9 , Kcne2 , Pln , Ryr2 , Scn5a , Tnni3 , Tnnt1 , Tnnt2 , Tpm1
familial periodic paralysisKcnj2
Familial Thoracic Aortic Aneurysm 1Mylk
Familial Thoracic Aortic Aneurysm 6Mylk
Familial Thoracic Aortic Aneurysm 7Mylk
Familial Ventricular TachycardiaRyr2
fatty liver diseaseAdrb2
Female InfertilityCacna2d2
Fetal Growth RetardationAgtr1a
FibrosisAdrb2 , Agtr1a
focal epilepsyCacna1h
focal segmental glomerulosclerosisAgtr1a
follicular thyroid carcinomaPrkar1a
Gastroenteritis, Transmissible, of SwineAtp1a1
Gastrointestinal DiseasesMylk
generalized dystoniaAtp1a3
Generalized EpilepsyAtp1a2
genetic diseaseAbcc9 , Atp1a2 , Atp1a3 , Cacna1c , Cacna1g , Hcn4 , Itpr1 , Kcnd3 , Kcnh2 , Ryr2 , Scn5a , Tnnt1 , Tnnt3 , Tpm2
Genetic Predisposition to DiseaseKcnj8
Gilles de la Tourette syndromeHcn4
Gillespie SyndromeItpr1
glaucomaMylk
glomerulosclerosisAgtr1a
glucose intoleranceAgtr1a
glycogen storage disease IITnnt2
glycogen storage disease IIIPln
Gonadal Dysgenesis, XX Type, with DeafnessPln
Graves' diseaseAdrb2
head and neck squamous cell carcinomaSntb1
Hearing LossCacna2d2
Hearing Loss, Noise-InducedKcne1 , Kcnq1
Heart BlockKcnj5
heart diseaseAtp2a2 , Kcna5 , Pln , Ryr2 , Tnni3 , Tnnt2
Heart InjuriesTnnt2
hemiplegiaScn5a
Hereditary Neoplastic SyndromesAdrb2 , Prkar1a
hereditary spastic paraplegia 7Scn5a , Tnni3
heroin dependenceChrm2
HirsutismCacna1g
human immunodeficiency virus infectious diseaseAdrb2
Huntington's diseaseAgtr1a , Itpr1
hydrocephalusAtp1a3
HyperalgesiaAdrb1 , Cacna1h , Itpr1
HypercholesterolemiaMylk
hyperekplexiaKcnq1
hyperekplexia 1Kcnq1
HyperemiaAdrb1
hyperglycemiaAdrb1
hyperhomocysteinemiaAtp1a1 , Atp1a2
hyperinsulinemic hypoglycemiaAbcc8 , Kcnj11
hyperinsulinismAbcc8 , Agtr1a , Kcnj11
Hyperlipoproteinemia Type IIAdrb2
Hyperphosphatasia with Mental Retardation Syndrome 2Tpm2
HyperplasiaAbcc8 , Kcnk1
hypertensionAbcc8 , Abcc9 , Adrb1 , Adrb2 , Agtr1a , Atp1a1 , Atp1a2 , Cacna1c , Fxyd2 , Kcna5 , Kcnj11 , Kcnj8 , Kcnq1 , Slc8a1 , Tpm1
Hypertensive NephropathyAgtr1a
hypertrichosisKcnj11
hypertrichotic osteochondrodysplasia Cantu typeAbcc9 , Kcnj8
HypertriglyceridemiaAdrb2
hypertrophic cardiomyopathyHcn4 , Kcne1 , Kcnh2 , Kcnj5 , Pln , Prkaca , Ryr2 , Scn5a , Tnnc1 , Tnni3 , Tnnt1 , Tnnt2 , Tpm1
hypertrophic cardiomyopathy 1Cacna1c , Tnni3 , Tnnt2 , Tpm1
hypertrophic cardiomyopathy 13Tnnc1
hypertrophic cardiomyopathy 18Pln
hypertrophic cardiomyopathy 2Tnnt2
hypertrophic cardiomyopathy 25Tnni3
hypertrophic cardiomyopathy 3Tpm1
hypertrophic cardiomyopathy 4Ryr2
hypertrophic cardiomyopathy 7Tnni3
Hypoglossal Nerve InjuriesPrkaca
hypoglycemiaAbcc8 , Cacna1c , Kcnj11
Hypoglycemia, Leucine-InducedAbcc8
hypokalemiaAdrb2
Hypomagnesemia, Seizures, and Mental Retardation 2Atp1a1
hypomyelinating leukodystrophy 7 with or without oligodontia and-or hypogonadotropic hypogonadismMylk
hypothyroidismAdrb2 , Atp2a2
HypoxiaItpr1
idiopathic generalized epilepsyCacna1h , Cacna2d2
IgA glomerulonephritisAgtr1a
Infant DeathRyr2 , Scn5a
InflammationAgtr1a
Insulin ResistanceAdrb2 , Atp1a2 , Kcnj11
intellectual disabilityCacna1g , Pln
intermediate coronary syndromeAgtr1a
interstitial cystitisAdrb2
Intestinal NeoplasmsKcnq1
intestinal pseudo-obstructionMylk
invasive ductal carcinomaDlg1
invasive lobular carcinomaAgtr1a
Iron OverloadAtp2a2
Jervell And Lange-Nielsen Syndrome 2Kcne1
Jervell-Lange Nielsen syndromeKcne1 , Kcnq1
Joubert syndrome 9Pln
juvenile myoclonic epilepsyCacna1g
KeloidTpm1
keratosis follicularisAtp2a2
kidney diseaseAdrb2 , Agtr1a
Kidney Reperfusion InjuryKcnj11
Language Development DisordersPln
Left Ventricular HypertrophyAdrb1 , Adrb2 , Agtr1a , Cacna1g , Hcn4 , Kcnj11 , Tnnt2
left ventricular noncompactionHcn4 , Ryr2 , Tpm1
Limb IschemiaAgtr1a
Liver InjuryAdrb2
Loeys-Dietz syndromeMylk
long QT syndromeAbcc9 , Cacna1c , Kcne1 , Kcne2 , Kcnh2 , Kcnj2 , Kcnj5 , Kcnq1 , Ryr2 , Scn5a , Snta1
long QT syndrome 1Kcnh2 , Kcnq1 , Scn5a
Long QT Syndrome 1/2Kcnh2 , Kcnq1
long QT syndrome 12Snta1
long QT syndrome 13Kcnj5
long QT syndrome 14Calm1
long QT syndrome 2Kcne1 , Kcnh2 , Kcnq1 , Scn5a , Snta1
Long QT Syndrome 2/3Kcnh2
Long QT Syndrome 2/5Kcne1 , Kcnh2
long QT syndrome 3Kcne2 , Kcnh2 , Scn5a
long QT syndrome 5Kcne1
long QT syndrome 6Kcne1 , Kcne2
long QT syndrome 9Kcnh2
low tension glaucomaAdrb1
lung diseaseAdrb2 , Agtr1a
Macular Dystrophy, Concentric AnnularRyr2
major depressive disorderChrm2
malignant gliomaAtp1b2 , Mylk
malignant mesotheliomaRyr2
Mammary Neoplasms, ExperimentalAgtr1a
Marfan syndromeKcnq1 , Mylk
maturity-onset diabetes of the youngAbcc8 , Kcnj11
maturity-onset diabetes of the young type 13Kcnj11
maturity-onset diabetes of the young type 2Kcnj11
medulloblastomaPrkar1a
megacolonSlc8a1
melanomaAbcc9 , Atp1a2 , Atp1b1 , Cacna1c , Kcnh2 , Mylk , Ryr2 , Scn5a
mental depressionChrm2
Metabolic SyndromeAdrb2 , Agtr1a
MetaplasiaKcnq1
methylmalonic aciduria and homocystinuria type cblCRyr2
methylmalonic aciduria due to methylmalonyl-CoA mutase deficiencyKcnh2 , Scn5a
microcephalyPln
middle cerebral artery infarctionAbcc8
migraineScn5a
migraine with auraAtp1a2
MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 1Scn5a
movement diseaseItpr1
Multiple AbnormalitiesAtp1a3 , Cacna1c , Cacna1g , Itpr1
muscular atrophyKcnh2
muscular diseaseTnni2
Muscular Dystrophy-Dystroglycanopathy (congenital with brain and eye anomalies), Type A, 11Snta1
myasthenia gravisAdrb2
myelodysplastic syndromePlcb1
myocardial infarctionAbcc9 , Adrb1 , Adrb2 , Agtr1a , Atp1a1 , Kcnj2 , Plcb1 , Pln , Tnni3 , Tnnt2
Myocardial IschemiaAdrb1 , Adrb2 , Atp1a1 , Cacna2d2 , Kcnj11 , Kcnj8 , Ryr2 , Slc8a1 , Tnnt2
Myocardial Reperfusion InjuryAbcc8 , Adrb1 , Adrb2 , Agtr1a , Atp1a1 , Atp2a2 , Kcnj11 , Kcnj8 , Pln , Slc8a1
myocardial stunningAtp2a2 , Pln
myocarditisAdrb2
MyxomaPrkar1a
Nasal PolypsAdrb2
NecrosisAbcc8 , Tnnt2
nemaline myopathyTnni3 , Tnnt1 , Tpm2
nemaline myopathy 4Tpm2
nemaline myopathy 5Tnnt1
NeointimaAtp2a2
neonatal diabetes mellitusAbcc8 , Kcnj11
Neoplasm InvasivenessMylk
Neoplasm MetastasisAgtr1a , Mylk
nephritisAgtr1a
nephrosclerosisAdrb1
Nerve DegenerationKcnj4
nervous system diseaseAdrb2
NesidioblastosisAbcc8 , Kcnj11
neurodegenerative diseaseItpr1
Neurodevelopmental DisordersItpr1
neurogenic bladderChrm2
newborn respiratory distress syndromeTnnt2
Niemann-Pick disease type AItpr1
nonalcoholic fatty liver diseasePrkaca
Nonprogressive Heart BlockScn5a
obesityAdrb1 , Adrb2 , Atp1a2 , Kcnh2
obstructive sleep apneaAdrb1
Oculootofacial DysplasiaKcnq1
open-angle glaucomaAdrb2
osteoarthritisAtp1a3
PainPlcb1
pancreatic ductal carcinomaAgtr1a
Pancreatitis, Experimental, Acute Atp2a2
Parkinson's diseaseAgtr1a , Dlg1 , Kcnj4
Parkinsonian DisordersAbcc8 , Abcc9 , Atp1a3 , Kcnj11 , Kcnj8
Paroxysmal DyspneaAdrb2
Paroxysmal Ventricular FibrillationCacna1c , Kcnh2 , Ryr2 , Scn5a , Snta1
patent ductus arteriosusAgtr1a
periodontitisAdrb1
peripheral nervous system diseaseCacna1h
permanent neonatal diabetes mellitusAbcc8 , Kcnj11
Permanent Neonatal Diabetes Mellitus, with Neurologic FeaturesAbcc8 , Kcnj11
phencyclidine abuseCalm1
Pituitary NeoplasmsAgtr1a
placental insufficiencyAgtr1a
pleomorphic xanthoastrocytomaChrm2
pneumoniaAdrb2 , Mylk
polycystic ovary syndromeAdrb2
polyhydramniosKcnq1
PolymicrogyriaAtp1a2
Postoperative Cognitive DysfunctionAgtr1a
prediabetes syndromeKcnj11
PrehypertensionPln
primary ciliary dyskinesiaTnni3 , Tnnt1
primary ciliary dyskinesia 2Tnni3
primary coenzyme Q10 deficiency 7Scn5a
primary hyperaldosteronismAtp1a1 , Cacna1h , Kcnj5
primary hypomagnesemiaFxyd2
primary immunodeficiency diseaseCacna1c
primary open angle glaucomaAdrb2
primary pigmented nodular adrenocortical diseasePrkaca , Prkar1a
Primary Pigmented Nodular Adrenocortical Disease, 1Prkar1a
Primary Pigmented Nodular Adrenocortical Disease, 4Prkaca
primary pulmonary hypertensionKcna5
Prinzmetal anginaKcnj8
progressive familial heart blockScn5a
Progressive Familial Heart Block Type IScn5a
progressive familial heart block type IAScn5a
Progressive Myoclonic Epilepsy 6Scn5a
prostate cancerAtp1a1 , Kcnj4 , Mylk
Prostatic NeoplasmsAdrb2 , Itpr1
proteinuriaAgtr1a
psoriasisAdrb2
psychotic disorderAtp1a3
Pulmonary Atresia with Intact Ventricular SeptumTpm1
pulmonary edemaAdrb2
pulmonary fibrosisAgtr1a
pulmonary hypertensionAgtr1a , Atp2a2 , Kcna5 , Slc8a1
Radiation Injuries, ExperimentalAgtr1a
renal cell carcinomaAgtr1a
renal hypertensionAgtr1a
renal hypomagnesemia 2Fxyd2
Renal Tubular DysgenesisAgtr1a
renovascular hypertensionAdrb1 , Agtr1a
Reperfusion InjuryAdrb1 , Adrb2 , Kcnj8 , Slc8a1
restrictive cardiomyopathyCacna1c , Tnni3 , Tnnt1 , Tnnt2
RetrognathiaAbcc8
Romano-Ward SyndromeKcne1 , Kcne2 , Kcnh2 , Kcnj5 , Kcnq1 , Scn5a , Snta1
sarcoidosisAgtr1a
schizophreniaAtp1a3 , Cacna1c , Cacna1h , Chrm2 , Dlg1 , Hcn4 , Kcnj5 , Plcb1
sciatic neuropathyAbcc8 , Abcc9 , Adrb2 , Kcnj11 , Kcnj8
seminomaKcne1 , Kcnq1
sensorineural hearing lossAtp1a1 , Atp1b1
SepsisAdrb2 , Mylk
short QT syndromeCacna1c , Kcnh2 , Kcnj2 , Kcnq1
Short QT Syndrome 1Kcnh2
Short QT Syndrome 2Kcnq1
Short QT Syndrome 3Kcnj2
sick sinus syndromeHcn4 , Kcnj5 , Scn5a , Snta1
Sick Sinus Syndrome 1, Autosomal RecessiveScn5a
Sick Sinus Syndrome 2, Autosomal DominantHcn4
skin diseaseKcnj2
Spastic Paraplegia Type 7Scn5a , Tnni3
Spinal Cord InjuriesAbcc8 , Atp2a2
Spinocerebellar Ataxia 42Cacna1g
Spinocerebellar Ataxia 42, Early-Onset, Severe, with Neurodevelopmental DeficitsCacna1g
spinocerebellar ataxia type 15Itpr1
spinocerebellar ataxia type 19/22Kcnd3
spinocerebellar ataxia type 29Itpr1
Spinocerebellar AtaxiasCacna1g , Itpr1
status epilepticusAbcc8 , Atp2a2 , Kcnj11 , Slc8a1 , Snta1
stomach cancerKcna5
Stomach NeoplasmsAdrb1 , Adrb2
StrokeAbcc8 , Mylk , Tnni3
Subarachnoid HemorrhageAbcc8
Subarachnoid Hemorrhage, TraumaticAbcc8
substance-related disorderAtp1b1 , Chrm2
Sudden DeathKcne1 , Kcnh2 , Ryr2 , Scn5a
Sudden Death, CardiacCacna1c , Hcn4 , Kcnh2 , Pln , Ryr2 , Scn5a , Tnnt2 , Tpm1
sudden infant death syndromeKcnh2 , Kcnj8 , Kcnq1 , Scn5a , Snta1
SyncopeScn5a
TachycardiaKcna5 , Ryr2
Tachycardia, SupraventricularKcnj2
tetralogy of FallotTpm1
thoracic aortic aneurysmMylk
Timothy syndromeCacna1c
Torsades de PointesKcne1 , Kcnh2 , Kcnq1 , Scn5a
toxic shock syndromeAdrb2
transient cerebral ischemiaItpr1
transient neonatal diabetes mellitusAbcc8 , Kcnj11
Transient Neonatal Diabetes Mellitus, 2Abcc8
Transient Neonatal Diabetes Mellitus, 3Kcnj11
TremorAdrb2 , Pln
trichorhinophalangeal syndrome type ISntb1
type 1 diabetes mellitusAbcc8 , Adrb1 , Chrm2 , Kcnj11
type 2 diabetes mellitusAbcc8 , Adrb2 , Atp2a2 , Calm1 , Kcnj11 , Kcnq1 , Pln
ulcerative colitisAdrb2
urticariaAdrb2
Usher syndrome type 2APln
vascular diseaseMylk
Vascular System InjuriesAgtr1a
Ventilator-Induced Lung InjuryAtp1a2
Ventricular DysfunctionAdrb1
Ventricular Dysfunction, LeftAdrb2 , Atp1a3 , Atp2a2 , Pln , Tnnt2
Ventricular Dysfunction, RightMylk
Ventricular FibrillationAbcc9 , Kcne2 , Kcnj2 , Kcnj8 , Ryr2 , Scn5a , Snta1
Ventricular Fibrillation, Paroxysmal Familial, 1Cacna1c , Kcnh2 , Ryr2 , Scn5a , Snta1
Ventricular RemodelingAgtr1a
Ventricular TachycardiaAbcc9 , Atp2a2 , Cacna1c , Hcn4 , Kcnh2 , Kcnj2 , Ryr2 , Scn5a , Tnnt2 , Tpm1
VentriculomegalyAtp1a3
vesicoureteral refluxAgtr1a
vestibular diseaseAtp1a1
Vestibulocochlear Nerve InjuriesAdrb2
viral encephalitisAdrb2
visual epilepsyAbcc8 , Atp1a3 , Kcnj11 , Plcb1 , Slc8a1
Weight GainCalm1
Weissenbacher-Zweymuller syndromeTnnt3
West syndromePlcb1
Wolff-Parkinson-White syndromeAbcc9 , Cacna1c , Kcnh2 , Kcnj2 , Kcnq1 , Ryr2 , Scn5a , Snta1 , Tnnt2
X-linked dilated cardiomyopathySnta1
Pathway Annotations Associated with Genes in the adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway
Pathway TermsGene Symbols
acebutolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein familyChrm2
adenosine monophosphate-activated protein kinase (AMPK) signaling pathwayCalm1
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Adrb2 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
aldosterone signaling pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
alfentanil pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
altered insulin secretion pathwayAbcc8 , Kcnj11
Alzheimer's disease pathwayAtp2a2 , Cacna1c , Calm1 , Itpr1 , Plcb1
amiloride pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
amiodarone pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
amlodipine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
angiotensin II signaling pathwayAgtr1a
angiotensin II signaling pathway via AT1 receptorAgtr1a
angiotensin III signaling pathwayAgtr1a
angiotensin III signaling pathway via AT1 receptorAgtr1a
apoptotic cell death pathwayPrkaca , Prkar1a
arrhythmogenic right ventricular cardiomyopathy pathwayAtp2a2 , Cacna1c , Cacna2d2 , Cacnb1 , Ryr2 , Slc8a1
atenolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
benazepril pharmacodynamics pathwayAgtr1a
bendroflumethiazide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
betaxolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
bile acid transport pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2 , Prkaca
bisoprolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
bumetanide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
bupivacaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
bupranolol drug pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
bupranolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
buprenorphine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
calcium transport pathwayAtp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacnb1 , Itpr1 , Ryr2 , Slc8a1
calcium/calcium-mediated signaling pathwayAdrb1 , Adrb2 , Agtr1a , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacnb1 , Calm1 , Chrm2 , Itpr1 , Kcnip2 , Mylk , Plcb1 , Pln , Prkaca , Ryr2 , Slc8a1 , Tnnc1 , Tnnc2
calcium/calmodulin dependent kinase 2 signaling pathwayCacna1c , Calm1 , Dlg1 , Pln , Ryr2 , Scn5a
candesartan pharmacodynamics pathwayAgtr1a
captopril pharmacodynamics pathwayAgtr1a
carvedilol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
Chagas disease pathwayPlcb1
chemokine mediated signaling pathwayPlcb1 , Prkaca
chloroprocaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
chlorothiazide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
chlorthalidone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
cilazapril pharmacodynamics pathwayAgtr1a
citalopram pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
cocaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
codeine and morphine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
cystinuria pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
desipramine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
diabetes mellitus pathwayAbcc8
dilated cardiomyopathy pathwayAdrb1 , Atp2a2 , Cacna1c , Cacna2d2 , Cacnb1 , Pln , Prkaca , Ryr2 , Slc8a1 , Tnnc1 , Tnni3 , Tnnt2 , Tpm1 , Tpm2
diltiazem pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
diphenoxylate pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
disopyramide pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
dobutamine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
dopamine signaling pathwayPrkaca
E-cadherin signaling pathwayDlg1
eicosanoid signaling pathwayPrkaca
enalapril pharmacodynamics pathwayAgtr1a
endocytosis pathwayAdrb1 , Adrb2
endothelin signaling pathwayPlcb1
Entamoebiasis pathwayPlcb1 , Prkaca
epinephrine signaling pathway via adrenergic receptor betaAdrb1 , Adrb2
eplerenone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
eprosartan pharmacodynamics pathwayAgtr1a
escitalopram pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
esmolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
etacrynic acid pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
ethylmorphine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
excitatory synaptic transmission pathwayKcnd3
felodipine pharmacokinetics pathwayCacna1c , Cacna2d2 , Cacnb1
fentanyl pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
flecainde pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
fluoxetine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
forasartsn pharmacodynamics pathwayAgtr1a
forkhead class A signaling pathwayAbcc8 , Kcnj11
fosinopril pharmacodynamics pathwayAgtr1a
fosphenytoin pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
fosphenytoin pharmacokinetics pathwayScn5a , Snta1 , Sntb1 , Sntb2
furosemide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
G protein mediated signaling pathway via Galpha12/Galpha13 familyAgtr1a
G protein mediated signaling pathway via Galphai familyAdrb2 , Chrm2
G protein mediated signaling pathway via Galphaq familyAgtr1a , Plcb1
G protein mediated signaling pathway via Galphas familyAdrb1 , Adrb2
gliclazide pharmacodynamics pathwayAbcc8 , Cacna2d2 , Cacnb1
glioma pathwayCalm1
glutamate signaling pathwayCacna1c , Itpr1 , Kcnj3 , Plcb1 , Prkaca
glyburide pharmacodynamics pathwayAbcc8 , Cacna2d2 , Cacnb1
glycogen degradation pathwayCalm1
gonadotropin-releasing hormone signaling pathwayCacna1c , Calm1 , Itpr1 , Plcb1 , Prkaca
granulocyte-macrophage colony-stimulating factor signaling pathwayPrkaca
Hartnup disease pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
Hedgehog signaling pathwayPrkaca
heroin pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
Huntington's disease pathwayItpr1 , Plcb1
hydrochlorothiazide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
hydrocodone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
hydroflumethiazide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
hydromorphone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
hypertrophic cardiomyopathy pathwayAtp2a2 , Cacna1c , Cacna2d2 , Cacnb1 , Ryr2 , Slc8a1 , Tnnc1 , Tnni3 , Tnnt2 , Tpm1 , Tpm2
ibutilide pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
iminoglycinuria pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
imipramine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
inositol phosphate metabolic pathwayPlcb1
insulin responsive facilitative sugar transporter mediated glucose transport pathwayCalm1
insulin secretion pathwayAbcc8 , Cacna1c , Kcnj11
insulin signaling pathwayCalm1 , Prkaca , Prkar1a
interleukin-3 signaling pathwayPrkaca
irbesartan pharmacodynamics pathwayAgtr1a
isoprenaline pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
isradipine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
lactose degradation pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
levacetylmethadol pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
levobunolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
levobupivacaine phgarmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
levorphanol pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
lidocaine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
lisinopril pharmacodynamics pathwayAgtr1a
long term depressionItpr1 , Plcb1
long term potentiationCacna1c , Calm1 , Itpr1 , Kcnd3 , Plcb1 , Prkaca
losartan pharmacodynamics pathwayAgtr1a
lysinuric protein intolerance pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
mepivacaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
methadone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
metolazone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
metoprolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
mexiletine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
mitogen activated protein kinase signaling pathwayCacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Prkaca
moexipril pharmacodynamics pathwayAgtr1a
N-cadherin signaling pathwayCalm1
nadolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
nalbuphine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
naloxone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
naltrexone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
nebivolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
neuron-to-neuron signaling pathway via the chemical synapseKcnj2 , Kcnj4
neurotrophic factor signaling pathwayCalm1
nicotine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
nifedipine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
nimodipine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
nisoldipine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
nitrendipine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
olmesartan pharmacodynamics pathwayAgtr1a
oxybuprocaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
oxycodone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
oxymorphone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
p38 MAPK signaling pathwayCalm1
penbutolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
pentazocine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
perindopril pharmacodynamics pathwayAgtr1a
phenytoin pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
phosphatidylinositol 3-kinase signaling pathwayCalm1 , Itpr1 , Plcb1
phosphatidylinositol 3-kinase-Akt signaling pathwayPrkaca
phosphoinositide metabolic pathwayPlcb1
pindolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
potassium channel inhibitors pharmacodynamics pathwayAbcc8 , Cacna2d2 , Cacnb1
prilocaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
prion disease pathwayPrkaca
procainamide pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
procaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
propranolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
prostaglandin I2 signaling pathwayMylk
protein kinase A (PKA) signaling pathwayPrkaca , Prkar1a
protein kinase C (PKC) signaling pathwayPlcb1
quinapril pharmacodynamics pathwayAgtr1a
quinidine pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
ramipril pharmacodynamics pathwayAgtr1a
remifentanil pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
renin-angiotensin cascade pathwayAgtr1a
Rho/Rac/Cdc42 mediated signaling pathwayAdrb1
ropivacaine pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
sleeping sickness pathwayPlcb1
sotalol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
spirapril pharmacodynamics pathwayAgtr1a
spironolactone pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
syndecan signaling pathwayPrkaca
T cell receptor signaling pathwayDlg1
telmisartan pharmacodynamics pathwayAgtr1a
timolol pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
torasemide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
tramadol pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Cacna2d2 , Cacnb1 , Fxyd2 , Kcnip2
trandolapril pharmacodynamics pathwayAgtr1a
trehalose degradation pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
triamterene pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
trichlormethiazide pharmacodynamics pathwayAtp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Fxyd2
tuberculosis pathwayCalm1
type 2 diabetes mellitus pathwayAbcc8 , Cacna1c , Cacna1g , Kcnj11
type II interferon signaling pathwayCalm1
valsartan pharmacodynamics pathwayAgtr1a
vascular endothelial growth factor signaling pathwayCalm1 , Prkaca
vasopressin signaling pathway via receptor type 2Prkaca
verapamil pharmacodynamics pathwayAbcc8 , Abcc9 , Adrb1 , Agtr1a , Atp1a1 , Atp1a2 , Atp1a3 , Atp1a4 , Atp1b1 , Atp1b2 , Atp1b3 , Atp1b4 , Atp2a2 , Cacna1c , Cacna1g , Cacna1h , Cacna2d2 , Cacnb1 , Calm1 , Chrm2 , Dlg1 , Fxyd2 , Hcn4 , Itpr1 , Kcna5 , Kcnd3 , Kcne1 , Kcne2 , Kcnh2 , Kcnip2 , Kcnj11 , Kcnj2 , Kcnj3 , Kcnj4 , Kcnj5 , Kcnj8 , Kcnk1 , Kcnq1 , Mylk , Plcb1 , Pln , Prkaca , Prkar1a , Ryr2 , Scn5a , Slc8a1 , Snta1 , Sntb1 , Sntb2 , Tnnc1 , Tnnc2 , Tnni1 , Tnni2 , Tnni3 , Tnnt1 , Tnnt2 , Tnnt3 , Tpm1 , Tpm2
visual phototransduction pathwayCalm1
Wnt signaling pathwayPlcb1 , Prkaca
Phenotype Annotations Associated with Genes in the adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway

References Associated with the adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway:

Ontology Path Diagram:

paths to the root

Import into Pathway Studio: