VASOPRESSIN SIGNALING PATHWAY VIA RECEPTOR TYPE 2 (PW:0000713)

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Description

Vasopressin (Avp) acts as an antidiuretic hormone and as a neuromodulator and neurotransmitter. Avp exerts its actions by binding to two receptor types, G-protein coupled receptors coupling to particular G alpha subunits of heterotrimeric G proteins. An important and probably the best characterized role of Avp is in the regulation of water homeostasis by signaling via receptor type 2. Water homeostasis is maintained through the regulation of intravascular blood volume and osmolality; the

Pathway Diagram:

Ariadne Genomics Inc. Aqp2 Gnas Adcy6 Gnas --+> Adcy6 cAMP water Aqp2 ---- Sipa1 Sipa1 Rab11a water reabsorption Akap7 ---- protein kinase A (PKA) signaling pathway Akap7 ---- Pde4d protein kinase A (PKA) signaling pathway --+> Aqp2 protein kinase A (PKA) signaling pathway --+> Aqp2 water ---> water reabsorption protein kinase A (PKA) signaling pathway --+> Pde4d Avpr2 ---- Gnas ATP ATP ---> cAMP cAMP --+> protein kinase A (PKA) signaling pathway Avp ---- Avpr2 Rab11a ---- Rab11fip2 Myo5b ---- Rab11a Myo5b ---- Rab11fip2 Pde4d ---| cAMP Pde4d Akap7 Rab11fip2 Snap23 Vamp2 Myo5b protein kinase A (PKA) signaling pathway G protein mediated signaling pathway via Galphas family Avp Avpr2
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Genes in Pathway:

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vasopressin signaling pathway via receptor type 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy2 adenylate cyclase 2 JBrowse link 1 37,043,071 37,698,390 RGD:10402751
G Adcy3 adenylate cyclase 3 JBrowse link 6 28,570,941 28,648,848 RGD:6907045
G Adcy6 adenylate cyclase 6 JBrowse link 7 140,270,678 140,291,722 RGD:2312656
RGD:6907045
RGD:2312654
RGD:2313211
G Adcy9 adenylate cyclase 9 JBrowse link 10 11,392,698 11,515,406 RGD:6907045
G Akap7 A-kinase anchoring protein 7 JBrowse link 1 21,129,213 21,263,850 RGD:2312656
RGD:1303982
G Aqp2 aquaporin 2 JBrowse link 7 141,237,802 141,242,837 RGD:2312656
RGD:6907045
RGD:1303982
RGD:2312654
RGD:2313211
G Aqp3 aquaporin 3 JBrowse link 5 57,423,735 57,429,252 RGD:6907045
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:6907045
G Arhgdia Rho GDP dissociation inhibitor alpha JBrowse link 10 109,754,012 109,757,506 RGD:6907045
G Arhgdib Rho GDP dissociation inhibitor beta JBrowse link 4 170,913,920 170,932,789 RGD:6907045
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:2312656
RGD:6907045
RGD:1579891
G Avpr2 arginine vasopressin receptor 2 JBrowse link X 156,889,006 156,892,707 RGD:2312656
RGD:10402751
RGD:6907045
RGD:2312654
RGD:1579891
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6907045
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:6907045
G Creb3l2 cAMP responsive element binding protein 3-like 2 JBrowse link 4 64,869,285 64,981,519 RGD:6907045
G Creb3l3 cAMP responsive element binding protein 3-like 3 JBrowse link 7 11,490,852 11,499,287 RGD:6907045
G Creb3l4 cAMP responsive element binding protein 3-like 4 JBrowse link 2 189,596,657 189,602,243 RGD:6907045
G Dctn1 dynactin subunit 1 JBrowse link 4 114,876,770 114,896,567 RGD:6907045
G Dctn2 dynactin subunit 2 JBrowse link 7 70,555,953 70,571,433 RGD:6907045
G Dctn4 dynactin subunit 4 JBrowse link 18 55,797,188 55,824,195 RGD:6907045
G Dctn5 dynactin subunit 5 JBrowse link 1 192,088,709 192,105,421 RGD:6907045
G Dctn6 dynactin subunit 6 JBrowse link 16 61,795,544 61,814,734 RGD:6907045
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 JBrowse link 6 134,958,854 135,085,769 RGD:6907045
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 JBrowse link 4 30,807,755 31,121,097 RGD:6907045
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 JBrowse link 3 57,817,677 57,868,854 RGD:6907045
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:6907045
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 JBrowse link 19 740,007 762,897 RGD:6907045
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 8 5,217,054 5,436,969 RGD:6907045
G Dync2li1 dynein cytoplasmic 2 light intermediate chain 1 JBrowse link 6 7,900,962 7,933,795 RGD:6907045
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:6907045
G Dynll2 dynein light chain LC8-type 2 JBrowse link 10 75,262,536 75,281,302 RGD:6907045
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:10402751
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:2312656
RGD:10402751
RGD:6907045
RGD:2312654
RGD:2313211
RGD:1579891
G Gnb1 G protein subunit beta 1 JBrowse link 5 172,914,025 172,981,403 RGD:10402751
G Gng12 G protein subunit gamma 12 JBrowse link 4 97,634,925 97,763,478 RGD:10402751
G Myo5b myosin Vb JBrowse link 18 70,426,865 70,729,985 RGD:2312656
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase JBrowse link 10 91,879,608 91,986,242 RGD:6907045
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:2312656
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:6907045
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:6907045
RGD:10402751
G Prkx protein kinase, X-linked JBrowse link X 45,080,963 45,125,095 RGD:6907045
G Rab11a RAB11a, member RAS oncogene family JBrowse link 8 70,192,975 70,215,719 RGD:2312656
RGD:6907045
G Rab11b RAB11B, member RAS oncogene family JBrowse link 7 18,598,991 18,612,132 RGD:6907045
G Rab11fip2 RAB11 family interacting protein 2 JBrowse link 1 281,065,346 281,101,163 RGD:2312656
G Rab5a RAB5A, member RAS oncogene family JBrowse link 9 5,910 6,065 RGD:6907045
G Rab5b RAB5B, member RAS oncogene family JBrowse link 7 3,104,530 3,123,384 RGD:6907045
G Rab5c RAB5C, member RAS oncogene family JBrowse link 10 88,621,924 88,645,364 RGD:6907045
G Sipa1 signal-induced proliferation-associated 1 JBrowse link 1 221,006,305 221,018,820 RGD:2312656
G Snap23 synaptosome associated protein 23 JBrowse link 3 112,333,972 112,362,960 RGD:2312656
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:6907045
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:2312656
RGD:6907045

Pathway Gene Annotations

Disease Annotations Associated with Genes in the vasopressin signaling pathway via receptor type 2
Disease TermsGene Symbols
46 XX gonadal dysgenesisFshr
Abnormal Cortical GyrationDync1h1
acrodysostosisPde4d
Acrodysostosis 2, with or without Hormone ResistancePde4d
acromegalyGnas
ACTH-Independent Macronodular Adrenal Hyperplasia 1Gnas
ACTH-secreting pituitary adenomaGnas
Acute Coronary SyndromeArhgdib
acute kidney failureAvp
acute lymphocytic leukemiaGnb1
adrenal carcinomaGnas
adrenal cortical adenomaPrkaca
Adrenal Gland NeoplasmsGnas , Prkaca
adrenocortical carcinomaGnas
Albright's hereditary osteodystrophyGnas
Alpers syndromeAqp4
Alzheimer's diseaseAqp4 , Dync1h1 , Gnas
amenorrheaFshr
amnestic disorderAvp
amphetamine abuseMyo5b , Pde4d
amyotrophic lateral sclerosisAqp4 , Dctn1
amyotrophic lateral sclerosis type 1Dctn1
Angina PectorisAvp
Animal Disease ModelsAqp4
anxiety disorderGnb1
asphyxiating thoracic dystrophyDync2h1 , Dync2li1
asphyxiating thoracic dystrophy 3Dync2h1
asthmaAdcy2 , Pde4d
autistic disorderAqp4 , Avp
autosomal dominant non-syndromic intellectual disability 13Dync1h1
autosomal dominant non-syndromic intellectual disability 18Creb3l4
autosomal dominant non-syndromic intellectual disability 42Gnb1
B-Cell Chronic Lymphocytic LeukemiaGnas
Beemer-Langer syndromeDync2h1
biliary tract benign neoplasmPrkacb
blindnessAqp4
brachydactylyGnas
brain edemaAqp4
Brain InjuriesAqp4 , Pde4d
brain ischemiaAqp3 , Aqp4 , Creb1 , Dynll1 , Prkaca , Prkacb
branched-chain keto acid dehydrogenase kinase deficiencyStx4
breast cancerGnas
Breast Cancer, FamilialDctn5
Breast NeoplasmsArhgdia , Dync2h1 , Gnas
Cafe-au-Lait SpotsGnas
cancerGnas
cardiac arrestDynll1
Cardiac ArrhythmiasAvp
cardiomyopathyAqp2 , Avp , Avpr2
central pontine myelinolysisAqp4
cerebellar ataxiaDync1h1
Cerebellar HypoplasiaDync1h1
cerebral amyloid angiopathyAqp4
Cerebral HemorrhageAqp4
cerebral malariaAqp4
Charcot-Marie-Tooth diseaseDctn1 , Dctn2 , Dync1h1
Charcot-Marie-Tooth disease axonal type 2ODync1h1
Charcot-Marie-Tooth disease type 2Dync1h1
ChloracneRab11a
cholangiocarcinomaGnas , Prkaca , Prkacb
chronic myeloid leukemiaSipa1
cleft palateGnb1
Cocaine-Related DisordersCreb1
Cognitive DysfunctionGnas
Colorectal NeoplasmsGnas
complex cortical dysplasia with other brain malformationsDync1h1
congenital adrenal hyperplasiaAvpr2
congestive heart failureAvp , Avpr2 , Dynll1 , Prkaca
CoughDync2h1
Cushing syndromeGnas
cystic fibrosisDctn4
DeafnessAqp4
DehydrationAvp
Delayed PubertyDync1h1
Developmental DisabilitiesCreb3l1 , Dync1h1 , Gnb1
diabetes insipidusAvp
diabetes mellitusAqp4
Diabetes Mellitus, Experimental Aqp2 , Aqp4 , Avp
diabetic angiopathyAdcy3
diabetic ketoacidosisAqp2
Diabetic NephropathiesAqp2 , Creb1
diabetic retinopathyAqp4
Diamond-Blackfan anemiaVamp2
diarrheaMyo5b
dilated cardiomyopathyCreb1
disease of cellular proliferationGnas
Distal Hereditary Motor Neuronopathy, Type VIIBDctn1
Distal Hereditary Motor Neuropathy, Type IDctn1
Drug OverdoseAvp
DysmenorrheaAvp
dystoniaDctn1 , Gnb1
Encephalopathy, Neonatal Severe, due to Mecp2 MutationsAvpr2
endocrine system diseaseGnas
epilepsyGnb1
Esophageal NeoplasmsAqp3
Experimental Autoimmune EncephalomyelitisAqp4
Experimental Liver CirrhosisArhgdib , Snap23
Failure to ThriveGnb1
familial nephrotic syndromeArhgdia
fatty liver diseaseCreb1
Fetal Growth RetardationDync2h1
GallstonesGnas
gastric adenocarcinomaGnas
Gastrointestinal HemorrhageAvp
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 9Stx4
genetic diseaseAvpr2 , Dync1h1 , Dync2h1 , Gnas , Gnb1 , Pde4d
granulosa cell tumorFshr
Growth DisordersAvpr2
growth hormone secreting pituitary adenomaGnas
head and neck squamous cell carcinomaGnas
hemorrhagic diseaseGnas
hepatocellular carcinomaGnas
Hereditary Neoplastic SyndromesDctn4
Herpes Simplex EncephalitisAqp4
Hirschsprung Disease 1Dync2h1
Histiocytoma, Angiomatoid FibrousCreb1
holoprosencephalyCreb1
human immunodeficiency virus infectious diseaseArhgdia , Arhgdib , Rab11b
Huntington's diseaseCreb1
hydrocephalusAqp4
hydronephrosisAqp2
HyperalgesiaAqp4 , Avp
hyperglycemiaAvp
hypertensionAqp2 , Aqp4 , Arhgdia , Avp , Avpr2 , Dynll1 , Gnas
hypertrophic cardiomyopathyPrkaca
HypoalgesiaAqp4
HypocalcemiaGnas
Hypoglossal Nerve InjuriesPrkaca , Prkacb
hypoglycemiaCreb1
HyponatremiaAvp
HypotensionAvp
Hypotension, OrthostaticGnas
hypothyroidismAqp3 , Gnb1
HypoventilationDctn1
HypoxiaGnas
idiopathic generalized epilepsyGnb1
impotenceDynll1
inappropriate ADH syndromeAvp
inherited metabolic disorderMyo5b
Insulin ResistanceGnas
intellectual disabilityAqp4 , Dync1h1 , Gnas , Gnb1
intestinal diseaseMyo5b
ischemiaAvp
KeloidArhgdia
Language Development DisordersGnb1
Lethal Congenital Contracture Syndrome 8Adcy6
lissencephalyDync1h1
liver benign neoplasmMyo5b
liver cancerGnas
lung adenocarcinomaGnas
lung small cell carcinomaAvp
Lymphatic MetastasisAqp3
malariaAqp4
Malformations of Cortical Development, Group IIDync1h1
McCune Albright syndromeGnas
melanomaGnas , Sipa1
Memory DisordersAvp , Creb1
Meniere's diseaseAqp4
mental depressionGnb1 , Pde4d
Metabolic Bone DiseasesGnas
microcephalyDync1h1
MicrognathismDync2h1
microvillus inclusion diseaseMyo5b
middle cerebral artery infarctionAqp4 , Dynll1
mood disorderAdcy9 , Dctn1
morbid obesityAdcy3
morphine dependenceCreb1
motor peripheral neuropathyDync1h1
Multiple AbnormalitiesDync1h1 , Gnas , Gnb1
Muscle HypotoniaDync1h1 , Gnb1
Muscle WeaknessDync1h1
muscular diseaseDync1h1
myelodysplastic syndromeGnb1
myocardial infarctionCreb1
Myocardial IschemiaRab5a , Snap23
myopathyDync1h1
nemaline myopathy 6Rab11a
Neoplasm MetastasisArhgdia
Neoplasm Recurrence, LocalCreb3l4
nephrogenic diabetes insipidusAqp2 , Aqp3 , Avpr2
Nephrogenic Syndrome of Inappropriate AntidiuresisAvpr2
nephrotic syndromeArhgdia
Nephrotic Syndrome, Type 1Arhgdia
Nephrotic Syndrome, Type 8Arhgdia
neuroblastomaGnas
neurodegenerative diseaseDctn1
NEURODEVELOPMENTAL DISORDER WITH ATAXIC GAIT, ABSENT SPEECH, AND DECREASED CORTICAL WHITE MATTERRab11b
neurohypophyseal diabetes insipidusAvp
neuromyelitis opticaAqp4
nonalcoholic fatty liver diseasePrkaca
obesityAdcy3 , Gnas
ocular hypertensionAqp4
OliguriaAvpr2
Optic Nerve InjuriesAqp4
optic neuritisAqp4
Opticospinal Multiple SclerosisAqp4
Ossification, HeterotopicGnas
osteogenesis imperfecta type 16Creb3l1
Ovarian DysgenesisFshr
Ovarian Dysgenesis 1Fshr
ovarian hyperstimulation syndromeFshr
Ovarian NeoplasmsAqp3 , Fshr
PainAvp
pancreatic adenocarcinomaGnas
pancreatic cancerGnas
Parasitic Liver DiseasesGnas
Parkinsonian DisordersAqp4 , Dctn1
Partial Agenesis of Corpus CallosumDync1h1
pathologic nystagmusGnb1
peripheral nervous system diseaseDync1i1
Perry syndromeDctn1
Pick's diseaseCreb1
Pigmented Nodular Adrenocortical Disease, Primary, 4Prkaca
PITUITARY ADENOMA 3, MULTIPLE TYPESGnas
Pituitary NeoplasmsGnas
pituitary-dependent Cushing's diseaseGnas
pleomorphic xanthoastrocytomaCreb3l2 , Dync1i1
Pneumococcal MeningitisAqp4
polycystic ovary syndromeFshr , Gnas
PolymicrogyriaDync1h1
PolyuriaAvp
portal hypertensionAvp
Precocious PubertyGnas
precursor lymphoblastic lymphoma/leukemiaGnb1
PresbycusisAqp4
primary biliary cirrhosisAqp4
primary hyperaldosteronismGnas
primary pigmented nodular adrenocortical diseasePrkaca
Progressive Osseous HeteroplasiaGnas
Prolonged Bleeding Time, Brachydactyly, and Mental RetardationGnas
prostate adenocarcinomaCreb3l4
prostate carcinoma in situCreb3l4
Prostatic NeoplasmsCreb3l4 , Pde4d , Prkacb , Stx4
pseudohypoaldosteronismGnas
pseudohypoparathyroidismGnas
Pseudohypoparathyroidism Type 1CGnas
pseudohypoparathyroidism type IBGnas
Pseudomonas InfectionsDctn4
pseudopseudohypoparathyroidismGnas
psychotic disorderAvp
Reperfusion InjuryAqp4
Respiration DisordersGnas
retinal diseaseAqp4
retinal vein occlusionAqp4
Rubinstein-Taybi syndromeAdcy9
Saldino-Noonan syndromeDync2h1
schizophreniaAvp , Creb1 , Gnas
sciatic neuropathyCreb1
Seizures, FebrileAvp
sex cord-gonadal stromal tumorGnas
ShockAvp
Short-Rib Thoracic Dysplasia 15 with PolydactylyDync2li1
short-rib thoracic dysplasia 6 with or without polydactylyDync2h1
Shy-Drager SyndromeAvp
sitosterolemiaDync2li1
Skin NeoplasmsAqp3
Smith-Magenis syndromeArhgdia , Dynll2 , Nsf , Rab5c
Spinal Cord InjuriesAqp4
spinal muscular atrophyDync1h1
Spinal Muscular Atrophy, Childhood, Proximal, Autosomal DominantDync1h1
Spinocerebellar AtaxiasDync1h1
squamous cell carcinomaAqp3
status epilepticusAqp4
strabismusGnb1
StrokeAvp , Pde4d
substance-related disorderAkap7
survival motor neuron spinal muscular atrophyDync1h1
synucleinopathyDctn1 , Dctn2
TachycardiaGnas
Talipes CavusDync1h1
temporal lobe epilepsyAqp4 , Avp , Nsf
TetanyGnas
thymomaAqp4
Tongue NeoplasmsAqp3
transient cerebral ischemiaAqp4 , Creb1 , Pde4d
Transverse MyelitisAqp4
type 2 diabetes mellitusAvp
ureteral obstructionAdcy6 , Avpr2
urinary bladder cancerAqp3
Uterine Cervical NeoplasmsGnas
uveitisAqp4
VACTERL associationDync2h1
vascular dementiaAvp
visual epilepsyCreb3l1 , Dync1h1 , Gnb1
Walker-Warburg syndromeAqp4
Weight GainDync1li2
West syndromeDync1h1
withdrawal disorderAvp , Creb1 , Gnas
X-linked monogenic diseaseAvpr2
Pathway Annotations Associated with Genes in the vasopressin signaling pathway via receptor type 2
Pathway TermsGene Symbols
acebutolol pharmacodynamics pathwayPrkaca
adenine phoshoribosyltransferase deficiency pathwayPde4d
adenosine monophosphate deaminase deficiency pathwayPde4d
adenosine signaling pathwayAdcy2 , Creb1 , Gnas , Gnb1 , Gng12 , Prkacb
adenylosuccinate lyase deficiency pathwayPde4d
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathwayPrkaca
AICA-ribosuria pathwayPde4d
amiloride pharmacodynamics pathwayAqp2 , Aqp3
amiodarone pharmacodynamics pathwayPrkaca
amlodipine pharmacodynamics pathwayPrkaca
amyotrophic lateral sclerosis pathwayRab5a
antigen processing and presentation pathwayCreb1
apoptotic cell death pathwayPrkaca , Prkacb , Prkx
atenolol pharmacodynamics pathwayPrkaca
autophagy pathwayRab11a , Rab5a
azathioprine pharmacodynamics pathwayPde4d
bendroflumethiazide pharmacodynamics pathwayAqp2 , Aqp3
betaxolol pharmacodynamics pathwayPrkaca
bile acid transport pathwayAdcy2 , Adcy3 , Adcy6 , Adcy9 , Aqp4 , Gnas , Prkaca , Prkacb , Prkx
bisoprolol pharmacodynamics pathwayPrkaca
bumetanide pharmacodynamics pathwayAqp2 , Aqp3
bupranolol drug pathwayPrkaca
bupranolol pharmacodynamics pathwayPrkaca
calcium/calcium-mediated signaling pathwayAdcy2 , Adcy3 , Adcy9 , Gnas , Prkaca , Prkacb , Prkx
carvedilol pharmacodynamics pathwayPrkaca
Chagas disease pathwayGnas
chemokine mediated signaling pathwayAdcy2 , Adcy3 , Adcy6 , Adcy9 , Gnb1 , Gng12 , Prkaca , Prkacb , Prkx
chlorothiazide pharmacodynamics pathwayAqp2 , Aqp3
chlorthalidone pharmacodynamics pathwayAqp2 , Aqp3
cilostazol pharmacodynamics pathwayPde4d
corticotropin-releasing hormone signaling pathwayGnas
cystinuria pathwayAqp2 , Aqp3
dilated cardiomyopathy pathwayAdcy2 , Adcy3 , Adcy6 , Adcy9 , Gnas , Prkaca , Prkacb , Prkx
diltiazem pharmacodynamics pathwayPrkaca
dipyridamole pharmacodyamics pathwayPde4d
disopyramide pharmacodynamics pathwayPrkaca
dobutamine pharmacodynamics pathwayPrkaca
dopamine signaling pathwayPrkaca , Prkacb
dopamine signaling pathway via D1 family of receptorsAdcy2 , Gnas , Gnb1 , Gng12 , Prkacb
E-cadherin signaling pathwayAqp3 , Stx4
eicosanoid signaling pathwayGnb1 , Prkaca , Rab11a
endocytosis pathwayRab11a , Rab11b , Rab11fip2 , Rab5a , Rab5b , Rab5c
endoplasmic reticulum stress - the unfolded protein response pathwayCreb3l1 , Creb3l2 , Creb3l3 , Creb3l4
endothelin signaling pathwayAdcy2 , Adcy3 , Adcy6
Entamoebiasis pathwayGnas , Prkaca , Prkacb , Prkx , Rab5a , Rab5b , Rab5c
epinephrine signaling pathway via adrenergic receptor betaGnas
eplerenone pharmacodynamics pathwayAqp2 , Aqp3
esmolol pharmacodynamics pathwayPrkaca
etacrynic acid pharmacodynamics pathwayAqp2 , Aqp3
flecainde pharmacodynamics pathwayPrkaca
follicle-stimulating hormone signaling pathwayAdcy2 , Creb1 , Fshr , Gnas , Gnb1 , Gng12 , Prkacb
forkhead class A signaling pathwayCreb1
fosphenytoin pharmacodynamics pathwayPrkaca
furosemide pharmacodynamics pathwayAqp2 , Aqp3
G protein mediated signaling pathway via Galpha12/Galpha13 familyGnb1
G protein mediated signaling pathway via Galphas familyAdcy2 , Adcy3 , Adcy6 , Adcy9 , Avpr2 , Gnas
glucagon signaling pathwayAdcy6 , Gnas
glutamate signaling pathwayAdcy2 , Adcy3 , Adcy6 , Adcy9 , Gnas , Gnb1 , Gng12 , Prkaca , Prkacb , Prkx
gonadotropin-releasing hormone signaling pathwayAdcy2 , Adcy3 , Adcy6 , Adcy9 , Gnas , Prkaca , Prkacb , Prkx
granulocyte-macrophage colony-stimulating factor signaling pathwayPrkaca , Prkacb
Hartnup disease pathwayAqp2 , Aqp3
Hedgehog signaling pathwayGnb1 , Prkaca , Prkacb , Prkx
histamine signaling pathway, immunologicalAdcy2 , Creb1 , Gnas , Gnb1 , Gng12 , Prkacb
Huntington's disease pathwayCreb1 , Creb3l1 , Creb3l2 , Creb3l3 , Creb3l4 , Dctn1 , Dctn2 , Dctn4
hydrochlorothiazide pharmacodynamics pathwayAqp2 , Aqp3
hydroflumethiazide pharmacodynamics pathwayAqp2 , Aqp3
hypoxia inducible factor pathwayCreb1
ibutilide pharmacodynamics pathwayPrkaca
iminoglycinuria pathwayAqp2 , Aqp3
insulin responsive facilitative sugar transporter mediated glucose transport pathwayMyo5b , Rab11a , Rab5a , Snap23 , Stx4 , Vamp2
insulin secretion pathwayVamp2
insulin signaling pathwayPrkaca , Prkacb , Prkx
interleukin-3 signaling pathwayPrkaca , Prkacb
isoprenaline pharmacodynamics pathwayPrkaca
isradipine pharmacodynamics pathwayPrkaca
Kelley-Seegmiller syndrome pathwayPde4d
Lesch-Nyhan syndrome pathwayPde4d
levobunolol pharmacodynamics pathwayPrkaca
lidocaine pharmacodynamics pathwayPrkaca
long term depressionGnas
long term potentiationPrkaca , Prkacb , Prkx
luteinizing hormone signaling pathwayAdcy2 , Creb1 , Gnas , Gnb1 , Gng12 , Prkacb
lysinuric protein intolerance pathwayAqp2 , Aqp3
melanocortin system pathwayAdcy2 , Gnas , Gnb1 , Gng12 , Prkacb
mercaptopurine pharmacodynamics pathwayPde4d
metolazone pharmacodynamics pathwayAqp2 , Aqp3
metoprolol pharmacodynamics pathwayPrkaca
mexiletine pharmacodynamics pathwayPrkaca
mitochondria transport pathwayDctn1 , Dctn2 , Dctn4 , Dctn5 , Dctn6 , Dync1h1 , Dync1i1 , Dync1i2 , Dync1li1 , Dync1li2 , Dynll1 , Dynll2
mitogen activated protein kinase signaling pathwayGng12 , Prkaca , Prkacb , Prkx
molybdenum cofactor deficiency pathwayPde4d
N-cadherin signaling pathwayDctn1
nadolol pharmacodynamics pathwayPrkaca
nebivolol pharmacodynamics pathwayPrkaca
neurotrophic factor signaling pathwayArhgdia , Arhgdib
nifedipine pharmacodynamics pathwayPrkaca
nimodipine pharmacodynamics pathwayPrkaca
nisoldipine pharmacodynamics pathwayPrkaca
nitrendipine pharmacodynamics pathwayPrkaca
Notch signaling pathwayRab11a
penbutolol pharmacodynamics pathwayPrkaca
phagocytosis pathwayDync1h1 , Dync1i1 , Dync1i2 , Dync1li1 , Dync1li2 , Dync2h1 , Rab5a , Rab5b , Rab5c
phenytoin pharmacodynamics pathwayPrkaca
phosphatidylinositol 3-kinase-Akt signaling pathwayPrkaca
pindolol pharmacodynamics pathwayPrkaca
platelet-derived growth factor signaling pathwayArhgdia , Sipa1
prion disease pathwayPrkaca , Prkacb , Prkx
procainamide pharmacodynamics pathwayPrkaca
propranolol pharmacodynamics pathwayPrkaca
prostaglandin D2 signaling pathwayAdcy2 , Gnas , Gnb1 , Gng12 , Prkacb
prostaglandin I2 signaling pathwayAdcy2 , Gnas , Gnb1 , Gng12 , Prkacb
prostate cancer pathwayCreb1 , Creb3l1 , Creb3l2 , Creb3l3 , Creb3l4
protein kinase A (PKA) signaling pathwayAdcy2 , Adcy3 , Adcy6 , Adcy9 , Akap7 , Pde4d , Prkaca , Prkacb
purine metabolic pathwayAdcy2 , Adcy3 , Adcy6 , Adcy9 , Pde4d
purine nucleoside phosphorylase deficiency pathwayPde4d
quinidine pharmacodynamics pathwayPrkaca
Rab family mediated signaling pathwayRab11a , Rab5a
serotonin signaling pathway via receptors engaging G alphas protein familyAdcy2 , Creb1 , Gnas , Gnb1 , Gng12 , Prkacb
sotalol pharmacodynamics pathwayPrkaca
spironolactone pharmacodynamics pathwayAqp2 , Aqp3
syndecan signaling pathwayPrkaca
timolol pharmacodynamics pathwayPrkaca
tioguanine pharmacodynamics pathwayPde4d
torasemide pharmacodynamics pathwayAqp2 , Aqp3
transforming growth factor-beta Smad dependent signaling pathwayCreb1
triamterene pharmacodynamics pathwayAqp2 , Aqp3
trichlormethiazide pharmacodynamics pathwayAqp2 , Aqp3
tuberculosis pathwayCreb1 , Rab5a , Rab5b , Rab5c
vascular endothelial growth factor signaling pathwayPrkaca
vasopressin signaling pathwayAdcy6 , Akap7 , Aqp2 , Avp , Avpr2 , Gnas , Myo5b , Pde4d , Rab11a , Rab11fip2 , Sipa1 , Snap23 , Vamp2
vasopressin signaling pathway via receptor type 1Avp
vasopressin signaling pathway via receptor type 2Adcy2 , Adcy3 , Adcy6 , Adcy9 , Akap7 , Aqp2 , Aqp3 , Aqp4 , Arhgdia , Arhgdib , Avp , Avpr2 , Creb1 , Creb3l1 , Creb3l2 , Creb3l3 , Creb3l4 , Dctn1 , Dctn2 , Dctn4 , Dctn5 , Dctn6 , Dync1h1 , Dync1i1 , Dync1i2 , Dync1li1 , Dync1li2 , Dync2h1 , Dync2li1 , Dynll1 , Dynll2 , Fshr , Gnas , Gnb1 , Gng12 , Myo5b , Nsf , Pde4d , Prkaca , Prkacb , Prkx , Rab11a , Rab11b , Rab11fip2 , Rab5a , Rab5b , Rab5c , Sipa1 , Snap23 , Stx4 , Vamp2
verapamil pharmacodynamics pathwayPrkaca
visual phototransduction pathwayGnb1
water transport pathwayAqp2 , Aqp3 , Aqp4
Wnt signaling pathwayPrkaca , Prkacb , Prkx
xanthinuria type I pathwayPde4d
xanthinuria pathwayPde4d
xanthinuria type II pathwayPde4d
Phenotype Annotations Associated with Genes in the vasopressin signaling pathway via receptor type 2
Phenotype TermsGene Symbols
abnormal olfactionAdcy3

References Associated with the vasopressin signaling pathway via receptor type 2:

Ontology Path Diagram:

paths to the root

Import into Pathway Studio: