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Pathways
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Ontology Browser
Term:
leptin system pathway (PW:0000363)
1 pathway diagrams for this term and its child terms. (View Interactive Pathway Diagram)     Standard Pathway Browser
Parent Terms Term With Siblings Child Terms
adenosine monophosphate-activated protein kinase (AMPK) signaling pathway  
altered energy homeostasis pathway +  
altered peptide and protein hormone signaling pathway +  
angiotensin signaling pathway +  
citric acid cycle pathway  
corticotropin-releasing hormone signaling pathway  
glucagon signaling pathway  
insulin signaling pathway +   
leptin system pathway  
Leptin acts on two populations of hypothalamic neurons that express orexigenic (feeding inducing) and anorexigenic genes, respectively. Leptin reduces the expression of genes from the former and enhances the expression of genes from the latter neurons. The leptin mediated response acts primarily via Jak-dependent activation of STAT.
View Interactive Diagram
melanocortin system pathway  
mTOR signaling pathway  
parathyroid hormone family signaling pathway +  
vasopressin signaling pathway +   

Synonyms
Related Synonyms: Signaling by Leptin ;   leptin-mediated signaling pathway
Definition Sources: GO:0033210, PMID:11239410, PMID:12079865, Reactome:R-HSA-2586552

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