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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
germ ring +    
protuberance +    
1st arch mandibular component +  
1st arch maxillary component +  
anal membrane 
animal cap +  
animal cap inner layer 
animal cap outer layer 
anterior neural tube +  
anterior visceral endoderm 
aortic sac +  
apical ectodermal ridge +  
archenteron +  
archenteron floor 
archenteron roof 
atrioventricular canal +  
axial mesoderm +  
bilaminar disc +  
blastocoel roof 
blastocyst +  
blastoderm +  
blastodisc +  
blastodisc derived epiblast 
blastopore +  
blastopore lip +  
Brachet's cleft 
bulbo-ventricular groove 
bulbus cordis +  
carapacial ridge +  
cardiogenic plate +  
cardiopharyngeal field +  
caudal ganglionic eminence 
caudal part of nephrogenic cord +  
chordal neural plate +  
chordamesoderm +  
chorionic villus +  
cloacal membrane +  
common atrial chamber +  
common cardinal vein +  
conotruncus 
copula linguae 
cytotrophoblast 
deep cell layer (gastrulation) 
definitive endoderm 
dorsal lateral ganglionic eminence 
dorsal meso-duodenum 
dorsal meso-oesophagus 
early proximal tubule 
ectodermal placode +  
ectoplacental cone +  
egg yolk 
embryoid body 
embryonic facial prominence +  
embryonic post-anal tail +  
embryonic tissue +  
embryonic urethral groove +  
endocardial cushion +  
epiblast (generic) +  
extravillous trophoblast 
facial bone primordium 
facio-acoustic VII-VIII preganglion complex +  
first pancreatic bud 
forehead protuberance 
ganglionic eminence +  
germ layer / neural crest +  
germ ring +  
glomeral mesenchyme +  
glossopharyngeal IX preganglion 
glossopharyngeal-vagus IX-X preganglion complex +  
gonadal ridge +  
hair follicle bulge 
head somite +  
hemisphere of embryo +  
hypoblast (generic) +  
hypopharyngeal eminence 
immature macula +  
infundibular recess of 3rd ventricle +  
inner cell mass +  
insect abdominal histoblast anlage +  
insect abdominal histoblast primordium +  
insect adult clypeo-labral anlage +  
insect anlage in statu nascendi 
insect Bolwig organ primordium +  
insect clypeo-labral anlage +  
insect clypeo-labral primordium +  
insect dorsal epidermis primordium +  
insect embryonic imaginal precursor +  
insect histoblast +  
insect lymph gland primordium +  
insect mesoderm anlage +  
insect neurogenic region 
insect presumptive embryonic/larval system +  
insect tracheal primordium +  
insect trunk ectoderm +  
insect trunk mesoderm anlage +  
insect ventral ectoderm +  
insect ventral epidermis primordium +  
insect visceral mesoderm +  
insect visual anlage +  
insect visual primordium +  
intermediate mesoderm +  
interrenal primordium +  
intersubcardinal venous anastomosis 
intraembryonic coelom +  
kidney rudiment +  
Koller's sickle 
Kupffer's vesicle 
lateral ganglionic eminence +  
lateral lingual swelling +  
lateral plate mesoderm +  
left horn of sinus venosus 
lingual swellings +  
marginal zone of embryo +  
maxillary prominence +  
medial ganglionic eminence 
median lingual swelling +  
mediastinum testis +  
mesocardium +  
metanephric cap 
Mullerian tubercle 
nephric ridge +  
nephrogenic cord +  
neural fold +  
neural fold hinge point 
neural groove +  
neural plate proneural cluster 
neural tube alar plate +  
notochordal plate +  
paired limb/fin field +  
pericardio-peritoneal canal +  
perioptic mesenchyme 
pharyngeal arch +  
pharyngeal membrane +  
pharyngeal pouch +  
pleuropericardial canals 
pleuropericardial folds 
pleuroperitoneal membrane 
polster 
post-anal gut 
posterior neural tube +  
prechordal mesoderm +  
prechordal plate +  
preputial swelling +  
presumptive cephalic mesoderm 
presumptive intervening zone +  
presumptive neuron neural tube 
presumptive structure +  
primary heart field +  
primitive groove 
primitive knot +  
Organizer for gastrulation in vertebrates. The primitive knot starts as a regional knot of cells that forms on the blastodisc immediately anterior to where the outer layer of cells will begin to migrate inwards - an area known as the primitive streak. Posterior to the node is the primitive pit, where the cells of the epiblast (the upper layer of embryonic cells) initially begin to invaginate. This invagination expands posteriorly into the primitive groove as the cells layers continue to move into the space between the embryonic cells and the yolk. This differentiates the embryo into the germ layers - endoderm, mesoderm, and ectoderm. The primitive knot migrates posteriorly as gastrulation proceeds, eventually being absorbed into the tail bud.[WP]. the regional thickening of cells at the rostral tip of the vertebrate primitive streak through which gastrulating cells migrate anteriorally to form tissues in the future head and neck; this region organizes the formation of the three embryonic layers and establishes the longitudinal axis and the polarity of the embryo[MP].
primitive pit 
primitive urogenital sinus +  
right horn of sinus venosus +  
rostral part of nephrogenic cord +  
secondary heart field +  
shelled egg +  
sinoatrial valve 
sinovaginal bulb +  
sinus of von Szily 
somatic layer of lateral plate mesoderm +  
somatopleure +  
splanchnic layer of lateral plate mesoderm +  
splanchnopleure +  
spleen primordium +  
syncytiotrophoblast +  
tectal plate +  
tracheal diverticulum 
tracheoesophageal fold +  
trophoblast +  
truncus arteriosus +  
trunk and cervical myotome group +  
tunica vasculosa lentis 
undifferentiated genital tubercle +  
urogenital membrane 
vaginal plate 
vasa hyaloidea propria 
venous vitelline plexus 
ventral ectodermal ridge 
ventral mesentery +  
ventral midline 
vitelline venous plexus 
yolk +  
yolk syncytial layer +  

Synonyms
Exact Synonyms: Hensen node ;   Hensen's node ;   Spemann Mangold organizer ;   Spemann's organizer ;   embryo organizer ;   embryonic organizer ;   embryonic shield ;   organizer ;   primitive node ;   shield
Broad Synonyms: node
Related Synonyms: DMZ ;   Henson's node ;   dorsal marginal zone ;   nodus primitivus
Alternate IDs: UBERON:0004018
Xrefs: AAO:0000346 ;   BILA:0000053 ;   BTO:0003395 ;   EHDAA2:0001272 ;   EHDAA:549 ;   EMAPA:16075 ;   FMA:293116 ;   GAID:1312 ;   MESH:A16.254.650 ;   NCIT:C34266 ;   SCTID:361464001 ;   TAO:0000071 ;   UMLS:C1283999 ;   VHOG:0000598 ;   Wikipedia:Regional_specification#Dorsal.2Fventral_axis_.26_organizer ;   XAO:0000072 ;   ZFA:0000071
Definition Sources: MP:0004066, Wikipedia:Primitive_knot, Wikipedia:Regional_specification#Dorsal.2Fventral_axis_.26_organizer

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