Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
blood brain barrier (UBERON:0000120)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
cell layer +    
nervous system +    
arthropod sensillum +  
basal cell layer of urothelium 
blood brain barrier +  
Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions.
blood nerve barrier +  
blood-air barrier 
blood-cerebrospinal fluid barrier 
central nervous system +  
chemosensory organ +  
ciliary marginal zone 
cuticle of hair 
dentate gyrus subgranular zone 
developing neuroepithelium +  
egg cylinder 
floor plate +  
ganglion +  
ganglionic eminence +  
glymphatic system 
granulosa cell layer +  
haemolymphatic fluid-testis barrier +  
insect adult nervous system +  
insect embryonic/larval nervous system +  
lateral ventricle subependymal layer 
layer of hippocampal field +  
mesangium +  
muscle spindle +  
myelin 
nerve plexus +  
nervous system cell part layer +  
neural system +  
neural tissue 
neuroendocrine gland +  
neuron projection bundle +  
perineural vascular plexus 
peripheral nervous system +  
photoreceptor array +  
primary nerve cord +  
regional part of nervous system +  
roof plate +  
segmental subdivision of nervous system +  
septum pellucidum +  
sheath of Schwann 
spongiotrophoblast layer 
stratum intermedium of tooth 
theca cell layer +  
ventral midline 
ventricle of nervous system +  
visual processing part of nervous system +  

Synonyms
Related Synonyms: BBB
Xrefs: MESH:D001812 ;   NCI:C13194 ;   UMLS:C0005854 ;   Wikipedia:Blood-brain_barrier ;   http://uri.neuinfo.org/nif/nifstd/nlx_subcell_100205
Definition Sources: DOI:10.1002/glia.20642, Wikipedia:Blood-brain_barrier

paths to the root