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Ontology Browser

Term:
glycine N-methyltransferase deficiency pathway (PW:0002299)
Annotations: Rat: (19) Mouse: (19) Human: (19) Chinchilla: (19) Bonobo: (19) Dog: (19) Squirrel: (19) Pig: (19)
Parent Terms Term With Siblings Child Terms
2-aminoadipic 2-oxoadipic aciduria pathway  
3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway  
3-hydroxyisobutyric aciduria pathway  
AGAT deficiency pathway  
alkaptonuria pathway  
aromatic L-amino acid decarboxylase deficiency pathway  
carnosinemia pathway  
dimethylglycine dehydrogenase deficiency pathway  
GABA aminotransferase deficiency pathway  
glutaric aciduria type I pathway  
glutathione synthase deficiency pathway  
glutathionuria disease pathway  
glycine N-methyltransferase deficiency pathway  
A condition due to defects in glycine N-methyltransferase (GNMT). As a component of methionine, homocysteine and folate metabolism among others, the defective enzyme potentially disrupts many metabolic pathways.
hawkinsinuria pathway  
histidinemia pathway  
homocarnosinosis pathway  
hyperhomocysteinemia pathway +   
hyperlysinemia pathway +   
hypermethioninemia pathway  
hypermethioninemia pathway  
hyperprolinemia type I pathway  
hyperprolinemia type II pathway  
inborn error of urea cycle pathway +   
isobutyryl-CoA dehydrogenase deficiency pathway  
isovaleric acidemia pathway  
lysinuric protein intolerance pathway  
maple syrup urine disease pathway  
mercaptolactate-cysteine disulfiduria pathway  
methylmalonate semialdehyde dehydrogenase deficiency pathway  
methylmalonic acidemia pathway +   
multiple carboxylase deficiency pathway +   
nonketotic hyperglycinemia pathway  
ornithine carbamoyltransferase deficiency pathway  
phenylketonuria pathway  
prolidase deficiency pathway  
propionic acidemia pathway  
sarcosinemia pathway  
succinic semialdehyde dehydrogenase deficiency pathway  
sulfite oxidase deficiency pathway  
tyrosinemia pathway +   

Synonyms
Exact Synonyms: hypermethioninemia due to GNMT deficiency pathway ;   hypermethioninemia due to glycine N-methyltransferase deficiency pathway
Related Synonyms: SMP:00222
Definition Sources: OMIM:606664

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