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Pathways
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Term:
radical SAM enzyme mediated metabolic pathway (PW:0001767)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
altered metabolic pathway of cofactors, vitamins, nutrients +    
ascorbic acid metabolic pathway 
biotin metabolic pathway  
cobalamin metabolic pathway +  
DNA modification pathway +    
fat-soluble vitamin metabolic pathway +    
folate metabolic pathway +    
glutathione metabolic pathway +   
histone modification pathway +    
homocysteine metabolic pathway +     
iron-sulfur cluster protein biogenesis pathway +    
lipoic acid metabolic pathway  
methionine cycle/metabolic pathway +    
molybdenum cofactor biosynthetic pathway +   
niacin metabolic pathway  
nicotinamide adenine dinucleotide metabolic pathway +     
pantothenic acid metabolic pathway +   
polyamine metabolic pathway +    
porphyrin and chlorophyll metabolic pathway +    
pyridine nucleotide biosynthetic pathway 
radical SAM enzyme mediated metabolic pathway +  
The radical SAM enzymes use their iron-sulfur (Fe/S) cluster(s) generate a radical using the S-adenosylmethionine (SAM) as the substrate. The intermediate radical allows these enzymes to mediate a vast range of chemical transformations important for co-factor and lipid metabolism, peptide and RNA modification.
riboflavin metabolic pathway  
tetrahydrobiopterin metabolic pathway 
thiamine metabolic pathway  
ubiquinone biosynthetic pathway  
vitamin B6 metabolic pathway  

Synonyms
Definition Sources: PMID:25477525

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