insulin biosynthetic pathway - Ontology Browser

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insulin biosynthetic pathway (PW:0001758)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)

Parent Terms

Term With Siblings

Child Terms

peptide and protein hormone metabolic pathway + is-a

insulin biosynthetic pathway

The insulin precursor, preproinsulin is subject to several processing steps in the endoplasmic reticulum and the Golgi apparatus before ending as the mature zinc-insulin hexamer stored in secretory granules. The expression of insulin is confined to the beta cells of the pancreatic islets of Langerhans.

preproglucagon processing pathway +

renin-angiotensin cascade pathway +

somatostatin biosynthetic pathway

thyroglobulin processing pathway +

thyroid-stimulating hormone biosynthetic pathway

thyrotropin-releasing hormone biosynthetic pathway

Synonyms
Related Synonyms:	Insulin processing ; preproinsulin processing pathway
Definition Sources:	GO:0030070, PMID:24843567, Reactome:R-HSA-264876

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