altered metabolic pathway of cofactors, vitamins, nutrients +
ascorbic acid metabolic pathway
biotin metabolic pathway +
cobalamin metabolic pathway +
fat-soluble vitamin metabolic pathway +
folate metabolic pathway +
glutathione metabolic pathway +
iron-sulfur cluster protein biogenesis pathway +
lipoic acid metabolic pathway
The metabolic reactions involving lipoic acid, a compound derived from octanoic acid that contains two sulfur centers. Lipoic acid is a co-factor for the pyruvate dehydrogenase complex responsible for the irreversible decarboxylation of pyruvate to acetyl-CoA.