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Ontology Browser

Term:
proton pump inhibitor drug pathway (PW:0000918)
Annotations: Rat: (11) Mouse: (10) Human: (11) Chinchilla: (9) Bonobo: (11) Dog: (10) Squirrel: (11) Pig: (10)
Parent Terms Term With Siblings Child Terms
acetylsalicylic acid drug pathway +   
anti-diabetic drug pathway +     
cimetidine drug pathway +   
diphenoxylate drug pathway +   
famotidine drug pathway +   
nizatidine drug pathway +   
pirenzepine drug pathway +   
prednisolone drug pathway +   
prednisone drug pathway +   
proton pump inhibitor drug pathway +   
The pharmacokinetics and pharmacodynamics of proton pump inhibitor (PPI), a class of compounds that block the acid secretion from parietal cells in the stomach. A representative PPI compound is omeprazole. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.
ranitidine drug pathway +   
roxatidine acetate drug pathway +   

Synonyms
Definition Sources: PharmGKB:http://www.pharmgkb.org/

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.