decreased CD4-positive, gamma-delta intraepithelial T cell number +
reduced number of a CD4-positive, gamma-delta T cell of the columnar epithelia such as in the gastrointestinal tract; intraepithelial T cells often have distinct developmental pathways and activation requirements
decreased CD8-positive, gamma-delta intraepithelial T cell number +
increased CD4-positive, gamma-delta intraepithelial T cell number