abnormal CD4-positive, gamma-delta intraepithelial T cell morphology +
abnormal CD8-positive, gamma-delta intraepithelial T cell morphology +
decreased gamma-delta intraepithelial T cell number +
increased gamma-delta intraepithelial T cell number +
greater number of a gamma-delta T cell present in columnar epithelia such as in the gastrointestinal tract; intraepithelial T cells often have distinct developmental pathways and activation requirements