abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell number +
absent T cells
decreased activated T cell number
decreased alpha-beta T cell number +
decreased double-negative T cell number +
decreased double-positive T cell number
decreased gamma-delta T cell number +
decreased memory T cell number +
decreased NK T cell number +
decreased regulatory T cell number +
reduced number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity