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Term:
Parent Terms Term With Siblings Child Terms
Abnormal aortic valve morphology +   
Abnormal atrioventricular valve morphology +   
Abnormal pulmonary valve morphology +   
Cardiac valve calcification +   
Cardiac valve vegetations 
Endocarditis infection occurs along the edges of the heart valves. Damage to the cardiac endothelium followed by platelet and fibrin deposition results in a sterile lesion known as nonbacterial thrombotic endocarditis (NBTE) or vegetation. Microbes entering the bloodstream via routine or invasive procedures adhere to the vegetation and are engulfed in an outer meshwork of fibrin and platelets. Subsequent rapid microbial multiplication in a protected area of impaired host defense leads to vegetation growth and continuous bacteremia.

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Definition Sources: PMID:17678415

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