Abnormal placental adhesion into the uterine wall +
Abnormal placental size +
Calcified placenta
Chorangioma
Choriocarcinoma
A malignant, trophoblastic and aggressive cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs and belongs to the far end of the spectrum of gestational trophoblastic disease (GTD), a subset of germ cell tumors.