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Ontology Browser

Parent Terms Term With Siblings Child Terms
Neural tube defect +   
A neural tube defect arises when the neural tube, the embryonic precursor of the brain and spinal cord, fails to close during neurulation. The cranial region (anencephaly) or the low spine (open spina bifida; myelomeningocele) are most commonly affected although, in the severe NTD craniorachischisis, almost the entire neural tube remains open, from midbrain to low spine.

Exact Synonyms: Abnormality of neural tube closure
Xrefs: MESH:D009436 ;   SNOMEDCT_US:253098009 ;   UMLS:C0027794
Definition Sources: HPO:probinson, PMID:19808787

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