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Term:
Parent Terms Term With Siblings Child Terms
Cholangitis +     
Granulomatous cholangitis 
Cholangitis characterized by the accumulation of granulomas. Granulomas are aggregates of modified macrophages (epithelioid cells) and other inflammatory cells that accumulate after chronic exposure to antigens. The underlying trigger may be exposure to noxious agents that cannot be biochemically degraded or to immune dysfunction. The ultimate result is a release of a variety cytokines that stimulate mononuclear cells that fuse to form multinucleated giant cells with a surrounding rim of lymphocytes and fibroblasts.
Lymphoid cholangitis 
Pleomorphic cholangitis 
Sclerosing cholangitis  
Suppurative cholangitis 

Synonyms
Definition Sources: PMID:22333006

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