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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
Abnormal muscle fiber protein expression +   
Abnormal muscle fiber-type distribution +   
Abnormal sarcomere morphology +   
Abnormality of skeletal muscle fiber size +   
Angulated muscle fibers  
Autophagic vacuoles  
Central core regions in muscle fibers  
The presence of disorganized areas called cores in the center of muscle fibers. There is a typical appearance of the biopsy on light microscopy, where the muscle cells have cores that are devoid of mitochondria and specific enzymes. Cores are typically well demarcated and centrally located, but may occasionally be multiple and of eccentric.
Centrally nucleated skeletal muscle fibers  
Deposits immunoreactive to beta-amyloid protein  
Fingerprint bodies 
Hypertrophied muscle fibers  
Increased endomysial connective tissue  
Motheaten muscle fibers  
Muscle fiber atrophy +   
Muscle fiber inclusion bodies +   
Muscle fiber necrosis  
Muscle fiber splitting  
Myelin-like whorls in vacuolated fibers 
Necklace skeletal muscle fibers  
Perifascicular muscle fiber atrophy 
Ragged-red muscle fibers  
Rimmed vacuoles  
Ring fibers 
Skeletal muscle autophagosome accumulation  
Spheroid bodies 

Synonyms
Exact Synonyms: Central core regions in muscle fibres
Xrefs: UMLS:C4022568
Definition Sources: https://orcid.org/0000-0001-9046-3540, PMID:17504518

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