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Ontology Browser

Parent Terms Term With Siblings Child Terms
Bronchiolitis obliterans  
Bronchiolitis obliterans organizing pneumonia  
Congenital pulmonary airway malformation +   
Desquamative interstitial pneumonitis  
Eosinophilic pneumonia 
Fibrocystic lung disease  
Glycogen accumulation in pulmonary interstitial cells 
Honeycomb lung  
Honeycombing represents destroyed and fibrotic lung tissue containing numerous cystic airspaces with thick fibrous walls, representing the late stage of various lung diseases, with complete loss of acinar architecture. The cysts range in size from a few millimeters to several centimeters in diameter, have variable wall thickness, and are lined by metaplastic bronchiolar epithelium. On chest radiographs, honeycombing appears as closely approximated ring shadows, typically 3-10 mm in diameter with walls 1-3 mm in thickness, that resemble a honeycomb; the finding implies end-stage lung disease. On CT scans, the appearance is of clustered cystic air spaces, typically of comparable diameters on the order of 3-10 mm but occasionally as large as 2.5 cm. Honeycombing is usually subpleural and is characterized by well-defined walls. It is a CT feature of established pulmonary fibrosis. Because honeycombing is often considered specific for pulmonary fibrosis and is an important criterion in the diagnosis of usual interstitial pneumonia, the term should be used with care, as it may directly impact patient care.
Hypersensitivity pneumonitis  
Interstitial pneumonitis +   
Intralobular interstitial thickening 
Lipoid pneumonia +   
Multiple pulmonary interstitial hyalinized nodules 
Peribronchovascular interstitial thickening  
Pleural cobblestoning 
Pulmonary amyloidosis 
Pulmonary fibrosis +   
Pulmonary granulomatosis +  
Pulmonary interstitial high-resolution computed tomography abnormality +   
Pulmonary interstitial lymphocyte infiltration +   
Pulmonary Langerhans cell histiocytosis 
Pulmonary necrosis 
Usual interstitial pneumonia  

Exact Synonyms: Honeycomb cysts ;   Honeycombing
Definition Sources: PMID:18195376

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