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Ontology Browser

Muscle fiber splitting (HP:0003555)
Annotations: Rat: (0) Mouse: (0) Human: (15) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
Abnormal muscle fiber protein expression +   
Abnormal muscle fiber-type distribution +   
Abnormal muscle glycogen content +   
Abnormal sarcomere morphology +   
Abnormality of skeletal muscle fiber size +   
Angulated muscle fibers  
Autophagic vacuoles  
Central core regions in muscle fibers  
Centrally nucleated skeletal muscle fibers  
Deposits immunoreactive to beta-amyloid protein  
Increased endomysial connective tissue  
Increased muscle lipid content +   
Motheaten muscle fibers 
Muscle fiber atrophy +   
Muscle fiber hypertrophy  
Muscle fiber inclusion bodies +   
Muscle fiber necrosis  
Muscle fiber splitting  
Fiber splitting or branching is a common finding in human and rat skeletal muscle pathology. Fiber splitting refers to longitudinal halving of the complete fiber, while branching originates from a regenerating end of a necrotic fiber as invaginations of the sarcolemma. In fiber branching, one end of the fiber remains intact as a single entity, while the other end has several branches.
Myelin-like whorls in vacuolated fibers 
Necklace skeletal muscle fibers  
Perifascicular muscle fiber atrophy 
Ragged-red muscle fibers  
Reduced muscle carnitine level  
Rimmed vacuoles  
Ring fibers 
Skeletal muscle autophagosome accumulation  

Exact Synonyms: Fiber splitting ;   Fibre splitting ;   Muscle fibre splitting
Xrefs: UMLS:C1836057
Definition Sources: PMID:6123177

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