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Term:
Impaired lymphocyte transformation with phytohemagglutinin (HP:0003347)
Annotations: Rat: (0) Mouse: (0) Human: (14) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
Abnormal B cell morphology +   
Abnormal lymphocyte count +   
Abnormal natural killer cell morphology +   
Abnormal T cell morphology +   
Absent microvilli on the surface of peripheral blood lymphocytes  
Impaired lymphocyte transformation with phytohemagglutinin  
Normal peripheral blood lymphocytes, when stimulated by phytohemagglutinin (PHA) are cytotoxic for homologous and heterologous cells but not for autologous cells in monolayer culture. The cytotoxic effect is thought to be indicative of the immunological competence of the lymphocytes.
Plasmacytosis 
Vacuolated lymphocytes +   

Synonyms
Xrefs: UMLS:C4025625
Definition Sources: https://orcid.org/0000-0002-0736-9199

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