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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
Generalized bone demineralization  
Osteomalacia  
Osteopenia  
Osteoporosis +   
Patchy reduction of bone mineral density 
Patchy variation in bone mineral density  
Rickets +   
Rickets is divided into two major categories including calcipenic and phosphopenic. Hypophosphatemia is described as a common manifestation of both categories. Hypophosphatemic rickets is the most common type of rickets that is characterized by low levels of serum phosphate, resistance to ultraviolet radiation or vitamin D intake. There are several issues involved in hypophosphatemic rickets such as calcium, vitamin D, phosphorus deficiencies. Moreover, other disorder can be associated with its occurrence such as absorption defects due to pancreatic, intestinal, gastric, and renal disorders and hepatobiliary disease. Symptoms are usually seen in childhood and can be varied in severity. Severe forms may be linked to bowing of the legs, poor bone growth, and short stature as well as joint and bone pain. Hypophosphatemic rickets are associated with renal excretion of phosphate, hypophosphatemia, and mineral defects in bones. The familial type of the disease is the most common type of rickets.

Synonyms
Exact Synonyms: Weak and soft bones
Xrefs: MSH:D012279 ;   SNOMEDCT_US:41345002 ;   UMLS:C0035579
Definition Sources: GARD:0005700

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