Neurofibrillary tangles - Ontology Browser

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Neurofibrillary tangles (HP:0002185)
Annotations: Rat: (0) Mouse: (0) Human: (22) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)

Parent Terms

Term With Siblings

Child Terms

Cerebral inclusion bodies + is-a

Argyrophilic inclusion bodies

Cerebral hyaline bodies

Hirano bodies

Lafora bodies

Lewy bodies

Neurofibrillary tangles

Pathological protein aggregates formed by hyperphosphorylation of a microtubule-associated protein known as tau, causing it to aggregate in an insoluble form.

Rosenthal fibers

Ubiquitin-positive cerebral inclusion bodies

Synonyms
Exact Synonyms:	Neurofibrillary tangles composed of disordered microtubules in neurons ; Paired helical filaments
Alternate IDs:	HP:0003132 ; HP:0007070
Xrefs:	MESH:D016874 ; SNOMEDCT_US:85775002 ; UMLS:C0085400
Definition Sources:	HPO:sdoelken

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