Fatty replacement of ventricular myocardial tissue
Focal necrosis of right ventricular muscle cells
Increased myocardial glycogen content
Increased myocardial pyrophosphate uptake
Left ventricular rupture
Myocardial fibrosis +
Myocardial fibrosis is characterized by dysregulated collagen turnover (increased synthesis predominates over unchanged or decreased degradation) and excessive diffuse collagen accumulation in the interstitial and perivascular spaces as well as by phenotypically transformed fibroblasts, termed myofibroblasts.