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Ontology Browser
Term:
negative regulation of low-density lipoprotein receptor activity (GO:1905598)
Annotations: Rat: (7) Mouse: (7) Human: (7) Chinchilla: (7) Bonobo: (7) Dog: (7) Squirrel: (7) Pig: (7)
Parent Terms Term With Siblings Child Terms
modulation by host of RNA binding by virus  
negative regulation of binding +   
negative regulation of catalytic activity +   
negative regulation of clathrin-dependent endocytosis  
negative regulation of DNA-binding transcription factor activity +   
negative regulation of guanyl-nucleotide exchange factor activity +   
negative regulation of low-density lipoprotein receptor activity  
Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.
negative regulation of molecular function in other organism +   
negative regulation of molecular function, epigenetic 
negative regulation of receptor internalization +   
negative regulation of receptor-mediated endocytosis involved in cholesterol transport  
negative regulation of RNA binding transcription factor activity 
negative regulation of signaling receptor activity +   
negative regulation of transporter activity +   
positive regulation of molecular function in other organism +  

Synonyms
Exact Synonyms: down regulation of LDL receptor ;   down regulation of LDLR activity ;   down regulation of low-density lipoprotein receptor activity ;   downregulation of LDL receptor ;   downregulation of LDLR activity ;   downregulation of low-density lipoprotein receptor activity ;   negative regulation of LDL receptor ;   negative regulation of LDLR activity
Narrow Synonyms: inhibition of LDL receptor ;   inhibition of LDLR activity ;   inhibition of low-density lipoprotein receptor activity
Definition Sources: GO_REF:0000059, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:22848640

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