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Ontology Browser

Term:
negative regulation of pyruvate dehydrogenase activity (GO:1904183)
Annotations: Rat: (5) Mouse: (5) Human: (5) Chinchilla: (0) Bonobo: (0) Dog: (5) Squirrel: (0) Pig: (5)
Parent Terms Term With Siblings Child Terms
negative regulation of cytokinin dehydrogenase activity 
negative regulation of D-amino-acid oxidase activity  
negative regulation of electron transfer activity +   
negative regulation of heme oxygenase activity 
negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity 
negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity 
negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity 
negative regulation of monooxygenase activity +   
negative regulation of NAD(P)H oxidase activity  
negative regulation of peroxidase activity +   
negative regulation of primary amine oxidase activity  
negative regulation of pyruvate dehydrogenase activity  
Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity.
negative regulation of succinate dehydrogenase activity 
negative regulation of superoxide dismutase activity 
positive regulation of pyruvate dehydrogenase activity  

Synonyms
Exact Synonyms: down regulation of pyruvate dehydrogenase activity ;   down regulation of pyruvic acid dehydrogenase activity ;   down regulation of pyruvic dehydrogenase activity ;   downregulation of pyruvate dehydrogenase activity ;   downregulation of pyruvic acid dehydrogenase activity ;   downregulation of pyruvic dehydrogenase activity ;   negative regulation of pyruvic acid dehydrogenase activity ;   negative regulation of pyruvic dehydrogenase activity
Narrow Synonyms: inhibition of pyruvate dehydrogenase activity ;   inhibition of pyruvic acid dehydrogenase activity ;   inhibition of pyruvic dehydrogenase activity
Definition Sources: GO_REF:0000059, GOC:dph, GOC:TermGenie, PMID:25525879

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.