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Ontology Browser

Term:
negative regulation of leucine-tRNA ligase activity (GO:1903634)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
negative regulation of DNA ligase activity 
negative regulation of glutamate-cysteine ligase activity 
negative regulation of leucine-tRNA ligase activity  
Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity.
negative regulation of proton-transporting ATP synthase activity, rotational mechanism 
positive regulation of isoleucine-tRNA ligase activity  
positive regulation of methionine-tRNA ligase activity  
positive regulation of threonine-tRNA ligase activity  

Synonyms
Exact Synonyms: down regulation of L-leucine:tRNALeu ligase (AMP-forming) ;   down regulation of leucine translase activity ;   down regulation of leucine-tRNA ligase activity ;   down regulation of leucine-tRNA synthetase activity ;   down regulation of leucyl-tRNA synthetase activity ;   down regulation of leucyl-transfer RNA synthetase activity ;   down regulation of leucyl-transfer ribonucleate synthetase activity ;   down regulation of leucyl-transfer ribonucleic acid synthetase activity ;   downregulation of L-leucine:tRNALeu ligase (AMP-forming) ;   downregulation of leucine translase activity ;   downregulation of leucine-tRNA ligase activity ;   downregulation of leucine-tRNA synthetase activity ;   downregulation of leucyl-tRNA synthetase activity ;   downregulation of leucyl-transfer RNA synthetase activity ;   downregulation of leucyl-transfer ribonucleate synthetase activity ;   downregulation of leucyl-transfer ribonucleic acid synthetase activity ;   negative regulation of L-leucine:tRNALeu ligase (AMP-forming) ;   negative regulation of leucine translase activity ;   negative regulation of leucine-tRNA synthetase activity ;   negative regulation of leucyl-tRNA synthetase activity ;   negative regulation of leucyl-transfer RNA synthetase activity ;   negative regulation of leucyl-transfer ribonucleate synthetase activity ;   negative regulation of leucyl-transfer ribonucleic acid synthetase activity
Narrow Synonyms: inhibition of L-leucine:tRNALeu ligase (AMP-forming) ;   inhibition of leucine translase activity ;   inhibition of leucine-tRNA ligase activity ;   inhibition of leucine-tRNA synthetase activity ;   inhibition of leucyl-tRNA synthetase activity ;   inhibition of leucyl-transfer RNA synthetase activity ;   inhibition of leucyl-transfer ribonucleate synthetase activity ;   inhibition of leucyl-transfer ribonucleic acid synthetase activity
Definition Sources: GO_REF:0000059, GOC:TermGenie, PMID:2280766

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