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Ontology Browser

Term:
negative regulation of pyruvate kinase activity (GO:1903303)
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Parent Terms Term With Siblings Child Terms
negative regulation of alpha-(1->3)-fucosyltransferase activity 
negative regulation of ATP citrate synthase activity  
negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity 
negative regulation of choline O-acetyltransferase activity 
negative regulation of CoA-transferase activity 
negative regulation of DNA nucleotidylexotransferase activity 
negative regulation of DNA primase activity 
negative regulation of DNA-directed DNA polymerase activity 
negative regulation of glucuronosyltransferase activity  
negative regulation of glycogen (starch) synthase activity  
negative regulation of glycogen synthase activity, transferring glucose-1-phosphate  
negative regulation of glycolytic process through fructose-6-phosphate  
negative regulation of kinase activity +   
negative regulation of NAD+ ADP-ribosyltransferase activity 
negative regulation of polynucleotide adenylyltransferase activity  
negative regulation of protein-glutamine gamma-glutamyltransferase activity 
negative regulation of pyruvate kinase activity 
Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.
negative regulation of RNA polymerase III activity 
negative regulation of RNA-directed 5'-3' RNA polymerase activity  
negative regulation of serine C-palmitoyltransferase activity  
negative regulation of SUMO transferase activity 
negative regulation of telomerase activity +   
negative regulation of ubiquitin-protein transferase activity +   
positive regulation of pyruvate kinase activity 

Synonyms
Exact Synonyms: down regulation of ATP:pyruvate 2-O-phosphotransferase activity ;   down regulation of phosphoenol transphosphorylase activity ;   down regulation of phosphoenolpyruvate kinase activity ;   down regulation of pyruvate kinase activity ;   downregulation of ATP:pyruvate 2-O-phosphotransferase activity ;   downregulation of phosphoenol transphosphorylase activity ;   downregulation of phosphoenolpyruvate kinase activity ;   downregulation of pyruvate kinase activity ;   negative regulation of ATP:pyruvate 2-O-phosphotransferase activity ;   negative regulation of phosphoenol transphosphorylase activity ;   negative regulation of phosphoenolpyruvate kinase activity
Narrow Synonyms: inhibition of ATP:pyruvate 2-O-phosphotransferase activity ;   inhibition of phosphoenol transphosphorylase activity ;   inhibition of phosphoenolpyruvate kinase activity ;   inhibition of pyruvate kinase activity
Definition Sources: GO_REF:0000059, GOC:mr, GOC:TermGenie, PMID:15804508

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.