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Ontology Browser
Term:
negative regulation of stem cell population maintenance (GO:1902455)
Annotations: Rat: (8) Mouse: (26) Human: (26) Chinchilla: (7) Bonobo: (7) Dog: (8) Squirrel: (7) Pig: (7) Naked Mole-rat: (7) Green Monkey: (7)
Parent Terms Term With Siblings Child Terms
germ-line stem cell population maintenance +   
maintenance of meristem identity +  
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process  
negative regulation of adiponectin secretion  
negative regulation of adipose tissue development  
negative regulation of age-related resistance 
negative regulation of aggregation involved in sorocarp development 
negative regulation of amyloid-beta clearance  
negative regulation of animal organ morphogenesis +   
negative regulation of anterior head development 
negative regulation of apical ectodermal ridge formation 
negative regulation of apoptotic process involved in development +   
negative regulation of appressorium formation 
negative regulation of basement membrane assembly involved in embryonic body morphogenesis 
negative regulation of behavior +   
negative regulation of biomineral tissue development +   
negative regulation of blood circulation +   
negative regulation of blood microparticle formation +  
negative regulation of blood vessel remodeling +   
negative regulation of bone development  
negative regulation of bone trabecula formation  
negative regulation of branching involved in lung morphogenesis +   
negative regulation of branching involved in ureteric bud morphogenesis  
negative regulation of branching morphogenesis of a nerve  
negative regulation of cardiac chamber formation +   
negative regulation of cardiac chamber morphogenesis 
negative regulation of cardiac endothelial to mesenchymal transition 
negative regulation of cardiac ventricle development +  
negative regulation of cardiocyte differentiation +   
negative regulation of cartilage development +   
negative regulation of cell activation +   
negative regulation of cell differentiation +   
negative regulation of cell differentiation involved in stem cell population maintenance 
negative regulation of chitin-based cuticle tanning +  
negative regulation of coagulation +   
negative regulation of cold-induced thermogenesis  
negative regulation of collecting lymphatic vessel constriction  
negative regulation of conidiophore stalk development 
negative regulation of corticotropin secretion  
negative regulation of cuticle pigmentation +  
negative regulation of cytokine production +   
negative regulation of dendrite development  
negative regulation of dendritic spine development +   
negative regulation of determination of dorsal identity  
negative regulation of developmental growth +   
negative regulation of digestive system process +   
negative regulation of eclosion 
negative regulation of ectoderm development  
negative regulation of embryo sac central cell differentiation 
negative regulation of embryo sac egg cell differentiation 
negative regulation of embryonic camera-type eye development 
negative regulation of embryonic development +   
negative regulation of embryonic pattern specification 
negative regulation of embryonic skeletal joint development 
negative regulation of endosperm development 
negative regulation of endothelial tube morphogenesis  
negative regulation of entry into reproductive diapause 
negative regulation of epidermal growth factor receptor signaling pathway involved in heart process 
negative regulation of epidermis development +   
negative regulation of epithelial cell migration +   
negative regulation of epithelial cell proliferation involved in prostate gland development  
negative regulation of epithelial cell-cell adhesion involved in epithelium migration 
negative regulation of epithelial to mesenchymal transition +   
negative regulation of epithelial tube formation 
negative regulation of fear response +   
negative regulation of female pigmentation 
negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation  
negative regulation of floral organ abscission 
negative regulation of formation of symbiont germ tube hook structure for appressorium development 
negative regulation of fusion cell fate specification 
negative regulation of fusion of sperm to egg plasma membrane 
negative regulation of germ cell proliferation +   
negative regulation of germ tube formation 
negative regulation of germinal center formation  
negative regulation of glomerular filtration +   
negative regulation of gonad development +   
negative regulation of gonadotropin secretion +   
negative regulation of hair cycle  
negative regulation of hair follicle development +   
negative regulation of haustorium mother cell formation 
negative regulation of heart induction 
negative regulation of heat dissipation 
negative regulation of heat generation +   
negative regulation of hemopoiesis +   
negative regulation of hepatocyte differentiation  
negative regulation of hyphopodium formation 
negative regulation of imaginal disc-derived leg joint morphogenesis 
negative regulation of imaginal disc-derived wing vein specification 
negative regulation of infection cushion formation 
negative regulation of inhibin secretion 
negative regulation of intestinal epithelial cell development  
negative regulation of isotype switching +   
negative regulation of juvenile hormone secretion 
negative regulation of keratinocyte differentiation  
negative regulation of kidney development +   
negative regulation of lactation 
negative regulation of lamellipodium morphogenesis  
negative regulation of leaf development 
negative regulation of leaf senescence 
negative regulation of lens epithelial cell proliferation 
negative regulation of lens fiber cell differentiation  
negative regulation of leukotriene production involved in inflammatory response 
negative regulation of lipoprotein particle clearance +   
negative regulation of lung alveolus development 
negative regulation of lung ciliated cell differentiation  
negative regulation of lung goblet cell differentiation  
negative regulation of lymphangiogenesis  
negative regulation of male germ-line stem cell asymmetric division 
negative regulation of male pigmentation 
negative regulation of mammary gland epithelial cell proliferation  
negative regulation of mammary stem cell proliferation 
negative regulation of maternal process involved in parturition 
negative regulation of mating type switching 
negative regulation of mesenchymal cell proliferation involved in lung development  
negative regulation of mesenchymal cell proliferation involved in ureter development  
negative regulation of mesoderm development +   
negative regulation of metanephric comma-shaped body morphogenesis  
negative regulation of metanephric S-shaped body morphogenesis  
negative regulation of metanephric ureteric bud development 
negative regulation of mitochondrial fission  
negative regulation of mitochondrial fusion  
negative regulation of morphogenesis of an epithelium +   
negative regulation of mucus secretion  
negative regulation of multicellular organism growth  
negative regulation of muscle adaptation +   
negative regulation of muscle contraction +   
negative regulation of muscle hypertrophy +   
negative regulation of muscle organ development +   
negative regulation of muscle tissue development +   
negative regulation of nematode male tail tip morphogenesis 
negative regulation of nervous system development +   
negative regulation of nervous system process +   
negative regulation of neural crest cell differentiation +  
negative regulation of neuron projection arborization  
negative regulation of neuron projection regeneration +   
negative regulation of neurotrophin production +   
negative regulation of oogenesis 
negative regulation of optic nerve formation 
negative regulation of organ growth +   
negative regulation of ossification +   
negative regulation of ovarian follicle development  
negative regulation of ovulation  
negative regulation of pancreatic A cell differentiation  
negative regulation of parathyroid hormone secretion 
negative regulation of penile erection  
negative regulation of photoreceptor cell differentiation +   
negative regulation of placenta blood vessel development  
negative regulation of plant organ morphogenesis 
negative regulation of plasma lipoprotein oxidation  
negative regulation of post-embryonic development +  
negative regulation of pre-B cell receptor expression  
negative regulation of pronephric nephron tubule development 
negative regulation of relaxation of muscle +   
negative regulation of renal albumin absorption  
negative regulation of renal amino acid absorption 
negative regulation of renal phosphate excretion  
negative regulation of renal sodium excretion +   
negative regulation of renal water transport 
negative regulation of respiratory burst involved in inflammatory response  
negative regulation of respiratory gaseous exchange  
negative regulation of retina development in camera-type eye +  
negative regulation of retinal cell programmed cell death +   
negative regulation of salivary gland boundary specification +  
negative regulation of sclerotium development 
negative regulation of seed dormancy process 
negative regulation of seed maturation 
negative regulation of shoot apical meristem development 
negative regulation of somatic muscle development +  
negative regulation of sperm capacitation  
negative regulation of spermatid nuclear differentiation 
negative regulation of spore germination +  
negative regulation of spore-bearing organ development +  
negative regulation of sporulation +  
negative regulation of stem cell population maintenance +   
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.
negative regulation of steroid hormone secretion +   
negative regulation of synapse maturation  
negative regulation of synaptic vesicle lumen acidification 
negative regulation of syncytium formation by plasma membrane fusion +   
negative regulation of synergid differentiation 
negative regulation of terminal cell fate specification, open tracheal system 
negative regulation of thyroid gland epithelial cell proliferation  
negative regulation of tissue remodeling +   
negative regulation of tolerance induction +   
negative regulation of transcytosis 
negative regulation of transport across blood-brain barrier +   
negative regulation of trichome patterning 
negative regulation of trophoblast cell migration  
negative regulation of tube lumen cavitation 
negative regulation of type B pancreatic cell development  
negative regulation of ureter smooth muscle cell differentiation  
negative regulation of vascular associated smooth muscle cell dedifferentiation  
negative regulation of vasculature development +   
negative regulation of vasoconstriction +   
negative regulation of very-low-density lipoprotein particle remodeling  
negative regulation of vitellogenesis 
negative regulation of Wnt signaling pathway involved in heart development  
neuronal stem cell population maintenance  
positive regulation of stem cell population maintenance +   
regulation of somatic stem cell population maintenance +   
regulation of stem cell population maintenance +   
somatic stem cell population maintenance +   

Synonyms
Exact Synonyms: down regulation of stem cell maintenance ;   downregulation of stem cell maintenance
Narrow Synonyms: inhibition of stem cell maintenance
Related Synonyms: down regulation of maintenance of pluripotency ;   downregulation of maintenance of pluripotency ;   inhibition of maintenance of pluripotency ;   negative regulation of maintenance of pluripotency
Definition Sources: GOC:hjd, GOC:TermGenie, PMID:22969033

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