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Pathways
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Term:
ubiquitin-dependent glycoprotein ERAD pathway (GO:0097466)
Annotations: Rat: (2) Mouse: (3) Human: (4) Chinchilla: (1) Bonobo: (1) Dog: (3) Squirrel: (1) Pig: (3) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
cellular response to glycoprotein +   
elastin catabolic process +   
maintenance of unfolded protein involved in ERAD pathway 
mannoprotein catabolic process  
negative regulation of ERAD pathway  
O-sialoglycoprotein catabolic process 
positive regulation of ERAD pathway  
protein deglycosylation involved in glycoprotein catabolic process +   
proteoglycan catabolic process +   
regulation of ERAD pathway +   
response to Thyroid stimulating hormone +   
retrograde protein transport, ER to cytosol +   
ubiquitin-dependent glycoprotein ERAD pathway +   
An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.

Synonyms
Exact Synonyms: ER-associated glycoprotein degradation ;   glycoprotein ERAD ;   gpERAD
Broad Synonyms: misfolded or incompletely synthesized glycoprotein catabolic process
Definition Sources: GOC:al, GOC:bf, PMID:16079177

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