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Ontology Browser

Term:
neurofibrillary tangle (GO:0097418)
Annotations: Rat: (5) Mouse: (5) Human: (5) Chinchilla: (5) Bonobo: (5) Dog: (5) Squirrel: (5) Pig: (5)
Parent Terms Term With Siblings Child Terms
inclusion body +     
aggresome  
Bunina body 
fibrillary inclusion 
glial cytoplasmic inclusion  
hyaline inclusion 
laminated body +  
Lewy body +   
Lewy body-like hyaline inclusion 
nematosome 
neurofibrillary tangle  
Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.
nuclear inclusion body +   
PHA granule 
Pick body 
skein-like inclusion 

Synonyms
Narrow Synonyms: flame-shaped neurofibrillary tangle ;   star-shaped neurofibrillary tangle
Xrefs: NIF_Subcellular:nlx_subcell_20090201 ;   NIF_Subcellular:nlx_subcell_20090202 ;   NIF_Subcellular:sao2409833926
Only In Taxon: NCBITaxon:33208 ! Metazoa
Definition Sources: NIF_Subcellular:nlx_subcell_20090201, NIF_Subcellular:nlx_subcell_20090202, NIF_Subcellular:sao2409833926

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