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Ontology Browser

Term:
mitochondrial outer membrane permeabilization (GO:0097345)
Annotations: Rat: (33) Mouse: (32) Human: (60) Chinchilla: (28) Bonobo: (31) Dog: (31) Squirrel: (32) Pig: (31)
Parent Terms Term With Siblings Child Terms
apoptosome assembly +  
extrinsic apoptotic signaling pathway +   
granzyme-mediated apoptotic signaling pathway  
hormone-mediated apoptotic signaling pathway  
intrinsic apoptotic signaling pathway +   
mitochondrial outer membrane permeabilization +   
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.
negative regulation of apoptotic signaling pathway +   
positive regulation of apoptotic signaling pathway +   
regulation of apoptotic signaling pathway +   
release of cytochrome c from mitochondria +   

Synonyms
Exact Synonyms: MOMP ;   mitochondrion outer membrane permeabilization
Broad Synonyms: mitochondrial outer membrane permeabilization during apoptotic cell death
Definition Sources: GOC:BHF, GOC:mtg_apoptosis, GOC:pg, PMID:21041309

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