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Ontology Browser
Term:
telomere maintenance via telomere trimming (GO:0090737)
Annotations: Rat: (8) Mouse: (8) Human: (17) Chinchilla: (8) Bonobo: (8) Dog: (8) Squirrel: (8) Pig: (9) Naked Mole-rat: (8) Green Monkey: (8)
Parent Terms Term With Siblings Child Terms
telomere maintenance +     
negative regulation of telomere maintenance +   
positive regulation of telomere maintenance +   
regulation of telomere maintenance +   
telomere capping +   
telomere maintenance in response to DNA damage +   
telomere maintenance via recombination +   
telomere maintenance via semi-conservative replication +   
telomere maintenance via telomere lengthening +   
telomere maintenance via telomere trimming +   
A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication.
telomeric loop disassembly +   
telomeric loop formation +   
 t-circle formation +   

Synonyms
Definition Sources: GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:27918544

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