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Ontology Browser

Term:
phosphorylation of RNA polymerase II C-terminal domain serine 2 residues (GO:0071619)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1)
Parent Terms Term With Siblings Child Terms
negative regulation of phosphorylation of RNA polymerase II C-terminal domain +  
phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex 
phosphorylation of RNA polymerase II C-terminal domain serine 2 residues +   
The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.
phosphorylation of RNA polymerase II C-terminal domain serine 5 residues +  
positive regulation of phosphorylation of RNA polymerase II C-terminal domain +   
regulation of phosphorylation of RNA polymerase II C-terminal domain +   

Synonyms
Definition Sources: GOC:krc, PMID:17079683

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