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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
CENP-A eviction from euchromatin 
chromatin remodeling at centromere +   
DNA repair-dependent chromatin remodeling  
epigenetic regulation of gene expression +   
nucleosome organization +   
R-loop processing  
A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.
transcription elongation-coupled chromatin remodeling  

Synonyms
Exact Synonyms: R-loop disassembly
Definition Sources: PMID:27252122, PMID:28790157, PMID:33986538

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